Alkaline phosphatase: ndozvakajairwa vakadzi, varume uye vana. Alkaline phosphatase muropa; ndozvakajairwa uye kutsauka

Alkaline phosphatase chiri enzayemu dzakananga, raiva boka hydrolases. enzayemu Izvi zvinogona kuonekwa munzvimbo dzose dzemuviri.

Kunyanya kuparadzirwa enzayemu kushingaira osteoblasts, intestinal mucosa goko, muna mammary shwanu, placenta, bile ducts pamadziro.

Mhando alkaline phosphatase

Phosphatase rakakamurwa marudzi akawanda:
- placental;
- itsvo;
- chiropa;
- E .;
- pfupa.

Alkaline phosphatase, uyewo makemikari ose akafanana nawo, tinofanira zvakaitika zvakasiyana nemakemikari mukati mumuviri womunhu. Zvaida Minimum uwandu alkaline phosphatase kuita zvavaifunga izvi. Uye kana muviri ane kutyorwa, zvinogona kureva kuti alkaline phosphatase wakawedzera. Zvikonzero zvibereko enzayemu ichi ingava yakasiyana.

Sei alkaline phosphatase

enzayemu ichi anoita kuita defosfolirovaniya. Izvi zvakaitwa ine iri cleavage pamusoro phosphate kubva Organic zvinhu musi wacho samolecular chechetere. Alkaline phosphatase muropa ane chenguva vamwe yevasungwa. The enzayemu anokwanisa tama phosphorus kuburikidza muchitokisi membrane. Uyezve, phosphatase - mumwe nechiyero dzemunharaunda calcium-phosphorus muviri. Basa mikuru enzayemu anoratidzwa mune ph svikiro siyana 8,6-10,1. Saka zita - riri alkaline.

Alkaline phosphatase muropa

Kuwanda zvairatidza dzose ropa kwevari alkaline phosphatase nokururamisira paupamhi. Kuverengwa dzinosiyana 44 Iu / L kusvika 147 Iu / L. Haafaniri pakarepo tidzikame kana alkaline phosphatase kwakawedzera. Zvikonzero zvingava zvachose chisingakuvadzi. Somuenzaniso, mwero pakati pavakadzi pamuviri Kazhinji rudo vanokosha zvishoma. Naiyewo dzakanaka uye kuyaruka, uyo akazarura padariro pakuyaruka. Zvose izvi imhaka kukura placenta uye pfupa, uye hazviratidzi zvakasiyana siyana abnormalities mumuviri womunhu. Uyewo kufunga phosphatase anoenderana nezera uye kurara kuti munhu.
Panguva iyoyo hapana kwezvipimo nzira, saka kusiyana parameters Norm kunobva reagents zvinoshandiswa murabhoritari yokutsvakurudza.

Alkaline phosphatase. wokuyera

Imwe nzira nokuti kusarudza abnormalities mu muviri alkaline phosphatase. Ndozvakajairwa vakadzi, varume uye vana zvishoma zvakasiyana, zvinofanira kucherechedzwa. Padanho enzayemu ichi pamuviri vari vakadzi zvishoma kuvatumwa mwero vanhu. Apo vana chokukomborerwa padanho enzayemu iri kupfuura nedzevakuru.

The zvazvingava zvakajairika kuti alkaline phosphatase iri pakati plasma mwana iri:

- in vacheche: 245-255 Iu / L;
- mune vana vane makore 1 kusvika 9 makore: 345-355 U / L;
- mune vana vane makore 10 kusvika makore 15: 275-285 U / L;
- kuyaruka, zera 16 kusvika 19 makore: 145-155 U / L.

Ndozvakajairwa vanhu:

makore makore 21 kusvika 30 -: 100-110 U / L;
- pakati pemakore 30 kusvika 45 makore: 110-120 U / L;
- pakati pemakore 46 kusvika 54 makore: 120-130 U / L;
- pakati pemakore 55 kusvika 70 makore: 135-145 U / L;
- makore '71: 180-190 U / L.

In vakuru, zvichienderana pasi, zvishoma yakasiyana alkaline phosphatase.

Ndozvakajairwa madzimai ndiwo:

makore makore 21 kusvika 30 -: 80-90 U / L;
- pakati pemakore 30 kusvika 45 makore: 90-100 U / L;
- pakati pemakore 46 kusvika 54 makore: 105-115 U / L;
- pakati pemakore 55 kusvika 70 makore: 125-135 U / L;
- makore '71: 155 -165ed / L;

Zvinogona vakagumisa kuti vanhu panyaya dzevakadzi nenhamba, zvishoma yakakwirira alkaline phosphatase. Ndozvakajairwa vakadzi idukusa mwero vanhu vanenge 20 U / L.

Zvikonzero kwakawedzera dziine alkaline phosphatase

Zvakanzi, iro zvinoenderana ari alkaline phosphatase. Norma rwuchiwanzwa, uye izvi varege kuva nengozi kuti utano. Asi zvinoitika ndiEzekieri, kana Zvakawanikwa indekisi ndiye wokutanga uye yakarurama nyevero mumuviri murwere zvinochengetwa zvinokosha kutyorwa.

On kuwedzera nhau yacho enzayemu kunogona kukanganisa:

Pamusoro chikamu biliary turakiti uye chiropa:

- bundu of bile mutsinga dzinofamba nemukaka;
- jaundice, izvo zvinogona kukonzera mhingaidzo pamusoro bile ducts;
- kenza chiropa;
- scarring of bile ducts, kushatiriswa maoparesheni;
- matombo ari bile ducts;
- kenza mudumbu kana rwatata;
- cirrhosis;
- Zvirwere mononucleosis;
- chero mavambo chiropa. In chirwere ichi mu-peta 3 kwakawedzera pamusoro alkaline phosphatase.

Zvikonzero kudivi njodzi mapfupa:

- Paget chirwere. chirwere ichi kunoratidzwa zvemamiriro mapfupa kukura, uyewo nokuvhiringidzirwa mune dzimwe nzvimbo mafupa mamiriro. In chirwere ichi, pane yakakwirira chaizvo kwevari enzayemu pasi kukurukurwa;
- pfupa mota;
- osteosarcoma, inova akaipa nebundu pamusoro pfupa;
- osteomalacia kushatiriswa karusiyamu kushaikwa (osteomalacia).

Other zvikonzero:

- myocardial infarction;
- hyperparathyroidism, inova hormone chirwere, kana vakachengeta ive nekumwisa parathyroid kemikari, parathyroid aumba. Nokuda chii zviri leaching calcium kubva mapfupa;
- intestinal perforation (kuburikidza-kukuvadza);
- maronda colitis.

Zvikonzero yakaderera kwevari alkaline phosphatase

Hakusi ndichingoti yakatsauka rakakwirira alkaline phosphatase. Ndozvakajairwa madzimai nevarume vanogona vanowanzotevedzera diverge uye pasi.

Kudonha phosphatase yomuropa zvingaita:

- ropa ropa huru mishonga;
- kupererwa neropa kwazvo;
- hypothyroidism (yakaderera thyroid shanda);
- gipofostataziya (vachiberekwa chisingawanzowaniki chirwere kuti kunokonzera kuti kunyoroveswa mapfupa);
- kukwana yakawanda zingi uye magnesium mumuviri;
- kukundikana placenta (vakadzi vane pamuviri).

Chii inokanganisa magumisiro

Kuwedzera:

- Panguva pamuviri, asi placenta rine alkaline phosphatase. Ndozvakajairwa madzimai iyi haisi kuonekwa kwazvo;
- pashure mitswe anotiwo yakawedzerwa mwero alkaline phosphatase;
- sezvo vana uye kuyaruka kwave akurumidze kukura mapfupa, mwero wacho enzayemu yakawedzera padanho kukurukurwa;
- kuwedzera padanho phosphatase muropa kunogona, uye zvimwe zvinodhaka, zvakadai se "paracetamol", "asipurini", "Allopurinol", nemishonga siyana, uye zvakasiyana-siyana zvimwe zvinodhaka;
- date enzayemu defosfolirovaniya anotoita inogona kuchengetwa, pashure kutonhora, wakatorwa panguva bvunzo ropa.

On achideredza pamusoro padanho enzayemu ichi kunogona kukanganisa nemumuromo pamuviri.

Analysis nokuti alkaline phosphatase

Panguva achitora kuongorora alkaline phosphatase muropa kuti anyatsoronga wacho serum kuwedzera chaizvo reagents kuti vakaitei kuna phosphatase. Zvadaro, achishandisa chaiyo nzira, wevasungwa chezvinhu vakawana kunoyerwa. In nomumwe zvinyama, ingava ura, chitaka kana placenta, rine pamusoro alkaline phosphatase imwe mhando. Munguva Kuongorora chakayerwa wevasungwa nezvevamwe enzayemu.

Kuti mumaoko pamusoro kuongorora ropa yokuenzanisira kuna enzayemu, murwere achada maminitsi mashoma. Mune zvimwe zviitiko, vanhu vane dumbu pashure kudya zvakanyanya yakabereka alkaline phosphatase. Panyaya iyi, kuti ongororo zvabuda zvinogona kukanganiswa. Naizvozvo, murwere anogona kutora zvokudya kana kunwa mvura pamberi hurukuro yacho kuongorora.

Nemhaka ano rabhoritari nzira, pakuongororwa takagadzirira pashure pemaawa mashomanana.

Zvichienderana ose data, tinogona kugumisa kuti shoma alkaline phosphatase muropa - vasingambooni chakaipa nazvo. Kuwedzera padanho enzayemu ichi zvingaita sezvo nyevero ipi zvarakasiya kana kutyorwa, uye zvachose pasina chikonzero chokushushikana. Chero zvazvingava, ichi hachisi rokupedzisira chinoratidza kuchinja dzemuviri.