Chii nguva prothrombin, uye chii mitemo yaro?

Prothrombin nguva, mwero icho nevakura 11-15 masekonzi, uye vana - 13-18 masekonzi, inogona hwakawedzera, inova chiratidzo chokuvapo zvemarudzi ose zvirwere. Nhamba iyi ndizvo kuti ini II plasma vakaratidza homeostasis akadana prothrombin yakaoma basa.

Kana prothrombin nguva inotanga kuwedzera, inoratidza tsika hypercoagulability. Izvi zvinogona kuva zvikonzero shoma:

· Kana prothrombin zvakaoma kunzwa kukundikana kukura coagulopathy sezvo gipoprokonvertinemiya uye hypoprothrombinemia.

· Dzimwe nguva, nhamba iyi yakawedzera pamberi amyloidosis, izvo zviri kukonzerwa kushayiwa chinhu X. Muchiitiko chino, zviri yokuita zvinoitwa amyloid. Kana nephrotic chirwere zvikamuka, ipapo kukundikana zvinhu VI uye V.

Sezvo kwetunhu prothrombin kunzwisisa zvinhu rikaitika chiropa, nokuti kunaka kana nhamba yavo ipfupi. Mune mamwe mamiriro ezvinhu, asi prothrombin nguva ndiyo inoratidza vasiri mamiriro muviri.

Kuwedzera indekisi iyi vakachengeta zvakare pamberi chakasimba uye chisingaperi chiropa, cirrhosis, uye akapa kuti subacute hepatic dystrophy nezvimwe maronda chiropa parenchyma. Chokwadi chokuti kuchinja aya chiratidzo zvakaipa uye tinopupura kuti kukura chero chirwere. Kana nechirwere jaundice, prothrombin nguva kungawedzera nokuti kuti chitsama bile kupinda ura ipfupi, iyo inotungamirira malabsorption vhitamini K. ndiye ave achishingaira munyaya kwetunhu prothrombin yakaoma.

Uyewo pakati zvinokonzera kuti anokonzera kuwedzera parameter ichi, anonzi enteropathy uye intestinal dysbacterioses izvo kukonzera chirwere kushayiwa vhitamini K. Kana marapirwo rinoitwa vachishandisa mhandu iri vhitamini, nokuputswa kupedza danho iri kwetunhu mikuru zvikonzero zviri prothrombin zvakaoma. Zvinofungidzirwa kuti kushandiswa coagulants zvinogona mberi kana prothrombin nguva kaviri.

Kune mishonga zvizhinji anogona kuwedzera nguva ino furemu indekisi. Pakati pavo vane laxatives, nemishonga, asipurini (akapa kushandiswa dzakakwirira mishonga) uye Quinine uye anabolic steroids.

Kazhinji, zvirwere chiropa prothrombin nguva indekisi ruchigona kuwedzera. Naizvozvo, kana uine chimwe chirwere mhando, zvakakodzera akuteerere chakarurama ichi.

Dzimwe nguva pane mamiriro ezvinhu umo prothrombin nguva inotanga kutapudzwa. Izvi zvinoratidza kuti pane tsika hypercoagulability. Dzimwe zvakadai inozadziswa kwokutanga nzendo thrombosis yezasi maoko nemakumbo, uye polycythemia. Kakawanda, chikamu inogona kuderedzwa kunonoka pamuviri kana mushure kushandisa zvimwe zvinodhaka, zvakadai acetylsalicylic asidhi (mu mishonga diki) merkaproturina uye kunanzvana pamuviri.

Kana vari kuongororwa kuti nemumuromo coagulation kurapa, iyo prothrombin nguva dzose kuongororwa. Zvisinei, mune zvinhu zvakadaro indekisi kuchinja kunogona kukonzerwa thromboplastin rinoshandiswa, izvo chinodiwa iyi. Nokuti zvinokosha zvikuru kuita tsvakurudzo pashure kushandisa-siyana thromboplastins. It anonzi chimwe chezvinhu zvinokosha mabasa emishonga hunobatsira. A murwere ari pasi pakuongorora, ongororo zvinofanira kuitwa nguva pashure kugadzwa itsva zvinodhaka.