NSAIDs - zvanzi zvinodhaka? NSAIDs: inopangidza. Chizvarwa chitsva NSAIDs

Chidimbu NSAIDs - zvinoita kuti ndikuudzei chinhu? Kana kwete, isu anoratidza vashoma kudzamisisa horizons angu uye kudzidza kuti zvinomiririra asinganzwisisiki tsamba idzi ina. Verenga nyaya - uye zvose zvichava pachena zvakakwana. Tinovimba kuti haasi mashoko chete, asiwo mafaro!

NSAIDs - inopangidza

Hatidi kuva refu kuti modokunetsa vaverengi vedu murima. NSAID anomirira vasiri steroidal Anti-anogumbura zvinodhaka - zvinodhaka munguva yedu dzakakurumbira chaizvo uye yakakurumbira, kuti vanokwanisa panguva kubvisa marwadzo uye kuderedza kuzvimba nenzira dzakasiyana-nhengo dzomuviri ... Kana kusvikira zvino hauna kumbobvira kuzomukazve mumwe kudiwa NSAID mushonga - ichi inogona kunzi rinenge chishamiso. Iwe - mumwe zvisingawanzoitiki luckies, chaizvoizvo, utano hwako unogona shanje!

Mberi anotevera mubvunzo uye pakarepo akatiudza pamusoro kududzirwa kweshoko "dzisiri steroidal". Izvi zvinoreva kuti zvinodhaka izvi hormone, kureva, It harina ayo maumbirwo chero mahormone. Uye zvakanaka kwazvo, nokuti isu tose tinoziva zvakawanda sei zvinogona nezvimwewo uye ngozi mahormone.

Zvikuru dzakakurumbira NSAIDs

Kana uchifunga kuti NSAIDs - mushonga mazita kashoma akataurwa muupenyu hwezuva nezuva, ipapo muri zvakaipa. Vanhu vakawanda havana kunyange kuziva kakawanda sei tichifanira kushandisa vasiri steroidal Anti-anogumbura zvinodhaka nokuda Mabatirwo siyana zvirwere pematanho vanhu kubvira kudzingwa Adhamu naEvha kubva paradhiso Kusch. Check out mazita mari yakadaro, zvechokwadi vamwe vavo vari venyu kumba mushonga cabinet. Saka, kune NSAIDs zvinosanganisira mishonga yakadai se:

• "Asipurini".
• "Amidopyrine".
• "Analgin".
• "Piroxicam".
• "Bystrumgel".
• "Diclofenac".
• "Ketoprofen".
• "Indomethacin".
• "Ketorol".
• "Naproxen".
• "Ketorolac".
• "Flurbiprofen".
• "Voltarengel".
• "Nimesil".
• "Diclofenac".
• "Ibuprofen".
• "Indopan".
• "Ipren".
• "Upsarin UPSA".
• "Ketanov".
• "Mesulid".
• "Movalis".
• "Hanayakanari".
• "Nurofen".
• "Ortofen".
• "Thrombotic ACC".
• "Ultrafen".
• "Fastum".
• "Finalgel".

Hongu, kuti zvose NSAID zvinodhaka. Zvawanyora akatendeuka akabuda, kunyange guru, asi, Chokwadi, iri kure wakakwana. Asi vachiri zvinopa pfungwa dzakasiyana-siyana ano vasiri steroidal Anti-anogumbura zvinodhaka.

A zvishoma chokwadi chenhau dzine

The tanga NSAID mishonga ave achizivikanwa vanhu kubva kare. Somuenzaniso, muIjipiti yekare, kubvisa kupisa uye kurwadziwa chaishandiswa chaizvo the willow omuti - munhu wechisikigo tsime salicylates uye mumwe wokutanga vasiri steroidal Anti-anogumbura zvinodhaka. Uye mumazuva iwayo vanachiremba kubatwa kwavo varwere vanenge vagari nemarwadzo uye fivha, decoction pamusoro pemiti uye ndimu nebharisami - ivo dzinewo salicylic acid.

Pakati pezana remakore rechi19 vakatanga kuva kemisitiri, izvo zvakasimbisa kukura pharmacology. Ipapo ongororo dzakati kuti dzakaitwa yokutanga zvinodhaka nziyo zvinobva muriwo mbishi zvinhu. Net salicin kubva the willow omuti akanga synthesized muna 1828 - raiva danho rekutanga pakusika yaizivikanwa kwatiri zvose "asipurini".

Asi richava zvizhinji makore tsvakurudzo pamberi mushonga achaberekwa. chiitiko Grand chakaitika muna 1899. Doctors uye varwere vavo vakakurumidza vaikoshesa zvikomborero mushonga. Muna 1925, apo Europe vakadonha zvinotyisa kupararira yokuSpain, "asipurini" akava muponesi guru vanhu vazhinji. Muna 1950, asiri steroidal Anti-anogumbura zvinodhaka waiva Guinness Book of Records sezvo rufimbi nepfungwa Vhoriyamu rokutengesa. Zvakanaka, zvino vemishonga zvakasikwa uye zvimwe nonsteroidal Anti-anogumbura zvinodhaka (NSAIDs).

In chii zvirwere Anti-anogumbura non-steroidal zvinodhaka anoshandiswa

Kuwanda chikumbiro rakafara chaizvo NSAIDs. Vane chaizvo panguva bata zvose chakasimba uye chisingaperi zvirwere achiperekedzwa marwadzo uye kuzvimba. Mazuva ava chipatapata kuti kutsvakurudza kudzidza efficacy zvinodhaka izvi pakurapa mwoyo uye vascular zvirwere. Uye chokwadi kuti vanogona kushandiswa kurwadziwa nomuzongoza, anozivikanwa nhasi anenge zvose (NSAIDs osteochondrosis vari ruponeso chaiwo).

Pano pasi chirwere mamiriro, ari chiitiko chinoratidza kushandiswa NSAIDs dzakasiyana:

• Fivhiri.
• Nomusoro, kutemwa nemusoro.
• Renal colic.
• Dzinonzi rheumatoid arthritis.
• Gout.
• Arthrosis.
• Osteoarthritis.
• Dysmenorrhea.
• Anogumbura arthropathies (psoriatic chearthritis, ankylosing spondylitis, Reiter kuti urwere).
• Postoperative marwadzo syndrome.
• Marwadzo chirwere nyoro kune mwero kunotevera uye siyana anogumbura kuchinja.

The kupatsanura pakati NSAIDs maererano nemakemikari mamiriro

Nokuverenga nyaya ino, iwe kare kuona kuti mishonga vasiri steroidal Anti-anogumbura zvakawanda. Kufamba pakati kanenge nani zvishoma, ngatiende kuwana kupatsanura izvi zvinhu. Kutanga, ivo inogona kupatsanurwa sezvinotevera: Group - boka asidhi uye NSAIDs - non-asidhi nomukaka.

Aimbova dzinosanganisira:

- salicylates (anogona pakarepo kuyeuka "asipurini").

- phenylacetic asidhi nomukaka ( "Aceclofenac," "Diclofenac" and said.).

- pyrazolidine (metamizole yavaibvisa, aizivikanwa vakawanda vedu se "Analgin" "phenylbutazone, etc.).

- oxicams ( "tenoxicam," "Meloxicam", "piroxicam" "tenoxicam").

- The nomukaka zviri indole acetic asidhi ( "Sulindac", "Indomethacin", etc.).

- rinobva iine acid propionic ( "Ibuprofen", etc ...).

Boka rechipiri - izvi:

- rinobva sulfonamide ( "Celecoxib", "Nimesulide", "Rofecoxib").

- alkanones ( "nabumetone").

Kupatsanura vasiri steroidal Anti-anogumbura zvinodhaka nokuda kubudirira kwavo

Kushandiswa NSAIDs apo kurapa osteochondrosis nezvimwe vadyi zvirwere vaikwanisa chaizvoizvo kushanda zvishamiso. Asi zvinosuwisa kwete mishonga vose vakaenzana zvinobudirira yavo. Vatungamiri Mhedziso anogona kunzi pakati pavo:

• "Diclofenac".
• "Ketoprofen".
• "Indomethacin".
• "Flurbiprofen".
• "Ibuprofen" uye dzimwe zvinodhaka.

Mishonga dzakanyorwa anogona kutaurwa chawo; t. e. kwakavakirwa pavo anogona kukudziridzwa uye kupinda chemishonga pomumbure NSAIDs itsva, asi pasi yakasiyana zita, uye akashandura kazhinji nomutengo kwirirei. Kuti varege kutambisa mari yako pasina, kudzidza kuva chitsauko chinotevera. Mashoko ari mairi, zvichakubatsira kuti kururama nechisarudzo.

Chii kutsvaka pakusarudza mishonga

NSAIDs - ichi, kazhinji kacho, mishonga yakanaka ano, asi, unouya chemishonga, zviri nani kuziva zvimwe nuances. Chii? Asi kuverenga!

Somuenzaniso, sarudzo kuti zviri nani kutenga "diclofenac", "Ortofen" kana "Voltaren". Uye iwe edza kubvunza kubva mishonga, izvo zvinodhaka izvi ndizvo zvakanakisisa. Ungangove, iwe uchava zano iyo anodhura. Asi chokwadi chokuti Zvinoumba zvinodhaka ava anenge zvakafanana. A musiyano mazita nokuti anogadzirwa pachishandiswa zvakasiyana yemakambani, yemadzibaba uye trademarks vakasiyana mumwe. The chete zvinogona kutaurwa Somuenzaniso, "indomethacin" uye "indomethacin" kana "ibuprofen" uye "Brufene" uye zvichingodaro. D.

Kuti tinzwisise kuvhiringidzika, nguva dzose nyatsotarira kavha, nekuti anofanira kupiwa huru vanoshingaira zvinodhaka fuma imomo. Chete zvakanyorwa kuti ingangova tsamba duku.

Asi kwete ndizvozvo zvose. Chaizvoizvo, kwete nyore! NSAID-analogue kuti kujairana mishonga ine unogona pakarepo kukonzera ane sema maitiro kana nemishonga kuti asati kuchengetwa. Chii chanetsa? The chikonzero anogona vavete mamwe yokuvirisa, izvo, chokwadi, iri kavha hapana yakanyorwa. Saka, tinofanira kudzidza zvakawanda uye mirayiridzo.

Kumwezve chikonzero dzakasiyana migumisiro analoginen zvinodhaka - musiyano iri chipimo chemushonga. Vasingazivi vanhu vasingawanzotauri kubhadhara chero kuteerera izvozvo, asi pasina. Handiti, mupfupi tabletochki ingasanganisira "bhiza" dose yezviri fuma. Asiwo, mapiritsi kana capsules huru chinoitika panofanira fillers nokuda zvakawanda 90 muzana.

Dzimwe nguva nevasori anowanikwa mune fomu retardirovannoy, t. E. Apo mishonga kumwezve (mazhinji) chiito. Chinokosha mishonga yakadaro ndiyo kukwanisa nyura zvishoma nezvishoma, zvokuti avo zvinogona kugara zuva rose. imwe gadziriro kwakadaro haafaniri kunwa 3 kana 4 kanomwe pazuva, zvakakwana kuva chete dose. Ichi chinowanikwa zvinodhaka zvinofanira sezvinoratidzwa pamusoro kavha kana iri rokuremekedza. Somuenzaniso, "Voltaren" iri chakakanganisika muchimiro inonzi "Voltaren kutadzisa."

List pamusoro analogues ose anozivikanwa zvinodhaka

Ratinoparidza ichi munyengeri papepa zvishoma tariro kuti richakubatsira nani kufamba nechikepe dzakawanda dzakanaka chemishonga package. Ngatitii iwe pakarepo zvinoda vanobudirira NSAIDs mu chemajoini kuti uderedze marwadzo. Akatora munyengeri jira verenga zvinotevera zvawanyora:

- analoginen "Diclofenac", tisingaverengi kare inotaurwa "Voltaren" uye "ortofen" ndiwo "Diklofen", "Dikloran", "Diklonak", "Rapten", "Diklobene", "Artrozan", "Naklofen".

- "Indomethacin" kutengeswa pasi pezvitsiga akadai "Indomin", "Indotard", "indomethacin", "Revmatin", "Indobene", "Inteban".

- analogues "Feldene" "Erazon", "pyroxene", "Roksik", "pyroxene".

- analogues "Ketoprofen", "Flexi", "Profenid", "Ketonal", "Artrozilen", "Knavon".

- A dzakakurumbira uye chipa "Ibuprofen" inowanika sechikamu zvinodhaka akadai "Nurofen", "Reumafen" "Brufen", "Bolinet".

rules NSAID

NSAIDs anogona chokuita zvinoverengeka nemishonga, saka inokurudzirwa kana raitongwa kuchengeta mitemo zvinotevera:

1. Verenga mirayiridzo kutevera kunenge kuti rine - zvinodiwa!

2. capsules Kana achiita kana mahwendefa tora navo girazi remvura - ichi achadzivirira dumbu rako. mutemo uyu anofanira kutevedzerwa kunyange kana kunwa zvinodhaka kupfuura ano (izvo vanoonekwa njodzi) nokuti mamwe renyevero haana unotema;

3. Rega pasi pashure pokutora mishonga inenge hafu yeawa. Chokwadi kuti simba regiravhiti achabatsira kuti ndima Kamudzira pasi yegurokuro nani;

4. Kubva doro anofanira kusiyiwa, semakasungwa pamwe NSAIDs uye doro - kongiri ngozi chinogona kukonzera siyana dumbu zvirwere.

5. Mumwe zuva, haufaniri kutora mbiri dzakasiyana non-steroidal zvinodhaka - nayo havazowandi yakanaka mugumisiro, asi muchidimbu nemishonga.

6. Kana mishonga asingadi kubatsira, bvunza chiremba wako, pamwe uri dose duku akumbirwa.

Marwadzo uye non-steroidal gastropathy

Zvino uchaona kuti ari NSAID gastropathy. Zvinosuruvarisa NSAIDs zvose kuratidza wandei nemishonga. Ivo kunyanya kunambwa pamusoro nemudumbu. Varwere vanogona kanganisa kuratidzwa akadai

• Svoto (dzimwe nguva yakasimba kwazvo).
• Chirungurira.
• Kurutsa.
• Dyspepsia.
• Ropa gastrointestinal.
• Manyoka.
• Duodenal urikanwi uye mudumbu.

Vose kumusoro dambudziko ndiro NSAID gastropathy. Somugumisiro, vanachiremba kakawanda aisirwe varwere vavo kuedza yakadereresa zvaibvira dose pamusoro chaiwo vasiri steroidal Anti-anogumbura zvinodhaka. Kurerutsa zvinokonzerwa pamusoro dumbu uye ura, Zvinokurudzirwa kuti haana kutora zvinodhaka izvi usina chawadya, uye kuita izvozvo chete pashure rinorema kudya.

Asi nezvinetso zvomudumbu zvomukati - hazvisi zvose parutivi zvinokonzerwa kuti vanokwanisa kubereka vamwe NSAIDs. Vamwe zvinodhaka anogona zvakaipa kukanganisa mwoyo uye neitsvo. Dzimwe nguva achitora kwavari angaperekedzwa nomusoro uye dzungu. Chimwe muchinetso chakakura - vane zvaparadza intra-articular shwashwa (Chokwadi, chete kushandiswa kwenguva refu). Sezvineiwo, kutengeswa chizvarwa chitsva NSAIDs, izvo kazhinji asingachaiti zvainovhiringidzawo izvi.

Nonsteroidal Anti-anogumbura zvinodhaka ari chizvarwa chitsva

Mumakore makumi maviri adarika, vakawanda nemakambani anogadzira mishonga ndashandisa kuva itsva NSAIDs ano, iyo, pamwe inobudirira utariri kurwadziwa uye kuzvimba, vaizova marwadzo sezvinobvira. Vemishonga takawana korona ubudirire - wose boka chizvarwa chitsva zvinodhaka yambokurukurwa, rinonzi haangotongi.

Fungidzira - zvinodhaka izvi pasi zvokurapa achitarisirwa inogona wakanwa refu chaizvo mapoka. Uye nguva kuyerwa kwete chete kwevhiki uye mwedzi uye kunyange kwemakore. Nemishonga boka iri havana avhiringidza pamusoro articular shwashwa, kurutivi Marwadzo ndoda uye vanopa zvinhu regai kukonzera matambudziko.

chizvarwa chitsva NSAIDs - zviri mishonga yakadai se:

• "Movalis".
• "Hanayakanari" (aka - "nimulid").
• "Arcoxia."
• "Celebrex".

Zvimwe zvakanakira isu ichatsanangura muenzaniso "Movalis". Inowanika somunhu kwakajairika piritsi (7.5 MG uye 15) uye suppositories 15 MG, uye girazi ampules kuti intramuscular Kutarisirwa (uyewo 15 MG). It anoshanda mushonga kwazvo nyoro, asi panguva imwe chete vakarongeka chaizvo: zuva rose riri zvakakwana chete piritsi. Kana varwere akaratidza kurapwa kwenguva refu kuti chearthritis ari muhudyu kana ibvi majoini, "Movalis" ndechokungoti irreplaceable.

Zvakasiyana siyana umo NSAIDs dziripo

nonsteroidal Anti-anogumbura zvinodhaka Most mukurumbira anogona kutengwa uye kushandiswa kwete chete ari muchimiro mahwendefa uye capsules nokuda nemumuromo kutarisira asiwo okuzora, gels, makenduru negadziriso jekiseni uye. Uye zvechokwadi yakanaka kwazvo, nokuti kusiyana-siyana ichi zvinoita dzimwe nguva kudzivisa kukuvadza panguva kurapwa pamwe mawa kugadzirwa zvakawanda nokukurumidza kuchirapa kushanda.

Saka, rudzi rutsva NSAIDs mu chemajoini kushandiswa jekiseni, ndoda simba pamusoro gastro-intestinal turakiti. Asi pane pafiripi divi kuti mari iyi: kana raitongwa intramuscularly, anenge zvose zvinodhaka non-steroidal anogona kubereka yematambudziko - necrosis kuti tsandanyama tishu. Ndokusaka NSAIDs jekiseni kumbobvira kwaiitwa kwenguva refu.

Kazhinji, majekiseni vanogadzwa ane exacerbation kuti anogumbura uye chinopedza zvirwere mapfundo nomuzongoza, achiperekedzwa kurwadziwa sabvumika. Pashure murwere nemamiriro inovandudzika, zvinovawo zvinobvira kuchinja kuti mapiritsi dzokunze nzira dziri kwamafuta.

Vanachiremba kazhinji sangana zvakasiyana chipimo chemushonga siyana, kusarudza chii uye kana zvinogona kuunza kubatsira zvikuru kumurwere. Mhedziso yakajeka: Kana usingadi kuti kukuvadza pachavo kuzvidzora Mabatirwo zvakafanana zvirwere zvakadai yakaderera musana kurwadziwa kana osteoarthritis, kumbira rubatsiro kupfungwa yokurapa, kuti ndipo uchakwanisa kubatsira.

Ndinogona kushandisa NSAIDs panguva pamuviri

Doctors vanokurudzira zvakasimba achitora NSAIDs kuvakadzi vane mimba (kunyanya yokurambidzwa nokuda wechitatu trimester), uye mums avo breastfeed. Zvinofungidzirwa kuti boka iri zvinodhaka zvinogona kukanganisa fetus gestation uye aite malformations siyana.

Maererano nemamwe mabhuku, ndiko chisingakuvadzi mushonga, runoonekwa nevakawanda sezvo "asipurini", unogona kuwedzera ngozi yokubva pamuviri yakakura mukutanga pamuviri. Asi dzimwe nguva vanachiremba zvinoratidza nachiremba vakadzi vanoshingaira zvinodhaka (zvakawanda mwero uye usingashandi mishonga). In nechimwe chiitiko, chisarudzo chinofanira kuitwa chiremba anokwanisa.

In pamuviri, kazhinji vakadzi vane dambudziko shure uye panodikanwa kugadzirisa dambudziko iri kushandisa zvinodhaka nonsteroidal antiinflammatory sechinhu vakarongeka chaizvo uye kutsanya. Panyaya iyi, akabvumira kushandiswa "Voltaren gel." Asi - zvakare - hwokuzvimirira kushandiswa kwayo zvinogoneka chete wokutanga uye chechipiri trimester, mu akazotevera pamuviri kushandisa ichi simba zvinodhaka anobvumirwa chete pasi yachiremba cherechedzo.

mhedziso

We ndakuudzai chii vaiziva pamusoro pachavo NSAIDs. Achiongorora zvaive abbreviations, kupatsanura pakati somushonga zvigadzirwa, mitemo kuteerera kwavo, mashoko pamusoro nemishonga - kunogona kubatsira muupenyu. Asi tinoda kuona kudiwa mishonga akasimuka kubva vaverengi vedu sezvo shoma sezvinobvira. Naizvozvo, panguva rokuonekana, tinoda imi zvakanaka simba utano!