The mushonga "Bicalutamide": mirayiridzo kushandiswa, description, akafanana uye wongororo

kenza yeprostate inonzi akaipa bundu kuti anova kubva epithelium pamusoro alveolar-cellular zvinoumba kweprostate gland. Ichi ndicho malignancy ari kusimba pabonde. Gore negore, nyika zvinyorwe 400 000 zviitiko kenza. mushonga aiwanzoshandisa kubata nayo se "Bicalutamide". Mirayiridzo yokushandisa, mutengo, ongororo, features, zviratidzo, nemishonga uye contraindications zvinodhaka dzinoturwa pazasi.

Kavha chigadzirwa, ayo chimiro uye Kuronga yokusunungurwa

In Wakadiniko kugadzirwa zvinodhaka "Bicalutamide"? Mirayiridzo yokushandisa, wongororo vanoti chokushandisa ichi rinowanika muchimiro rwakapoteredza biconvex chena film-zvemapuranga uye zvemapuranga mahwendefa. Ndivo basa chirungiso ndiyo bicalutamide. Mukuwedzera, murwiyo rinosanganisira medicament: lactose monohydrate, chibage starch, yavaibvisa stearyl fumarate, yavaibvisa croscarmellose, povidone, Opadry chena, Polyvinyl doro, titanium dioxide, polyethylene glycol uye talc.

In yavakatengesa zvinodhaka anouya mhoni packs it kana hombodo dzemvura murima, zapechatennyh mubhokisi kubva kuvakwa mapepa.

Features zvinodhaka

Chii chinodhaka "Bicalutamide"? Mirayiridzo dzokushandisa kunoratidza kuti anyatsosarudza vasiri steroidal Anti androgen chisingazivi nevamwe mhando kwemakemikari anobudiswa basa.

Viewed medicament inokwanisa tichisunga kuti androgen Kanotokonya uye kwete simba kutaura majini kutitadzise stimulatory mugumisiro androgens. Mugumisiro simba iyi regression neoplasms (nyanyisa) kenza kweprostate.

Vamwe vanhu vanorega kugamuchira bicalutamide kukonzera Anti-androgen kurega syndrome.

Kinetics zvinodhaka

Apo Absorção de Água zvinodhaka "Bicalutamide"? Mirayiridzo yokushandisa inoreva kuti avo vanoshingaira wemafuta pashure kutora mapiritsi zvachose uye nokukurumidza woga kubva ura. Kudya zvokudya hakuna zvainoita Absorção de Água zvinodhaka.

The hafu-upenyu pomutumwa anenge 7 days. Nguva piritsi wevasungwa kuti basa pazvokudya ropa yakawedzera ne10 nguva. Saka, refu hafu-upenyu zvinodhaka zvinoita kuti tikwanise kushandisa kamwe pazuva.

Ukama kuti mapuroteni eplasma iyi unosvikirwa pamatunhu. Zvinonzi nezvo metabolised nokuda chiropa, zvichiguma nokuumbwa basa nomukaka.

umboo

Apo prescribers "Bicalutamide" (Mahwendefa)? Mirayiridzo dzokushandisa mishumo inotevera uchapupu hwake:

• kenza yeprostate kupararira (ikashandiswa pamwe kuvhiya castration kana GnRH analoginen);
• kenza yeprostate munharaunda mberi (muchimiro monotherapy pamwe radiotherapy kana adjuvant kurapa akabatana yakakura prostatectomy);
• non-metastatic kenza yeprostate, munharaunda mberi (apo kuvhiya castration kana zvimwe navanachiremba kupindira hakubvumirwi).

Kurambidzwa kushandiswa mari

Kana kwete taurira mushonga "Bicalutamide"? Mirayiridzo pakushandisa hwokuti mishonga iyi hazvigoni kushandiswa kana hypersensitivity kuti zvayaigadzirwa, concomitantly ne "cisapride", "terfenadine" kana "astemizole," uyewo lactase kushayiwa pauduku, apo lactose kusashivirira, varwere vari hadzi bonde uye shuga-galactose malabsorption.

Zvokungwarira Mahwendefa akadaro pachii havachanyatsogoni chiropa chaitika.

Drug "Bicalutamide": mirayiridzo kushandiswa

Mutengo zvinodhaka izvi akanyorwa pakuguma nyaya. Tora zvinofanira kuva mukati.

mushonga uyu ushandiswe vanhurume mukuru chete, kusanganisira varwere vakwegura.

With kwakapararira kenza yeprostate akabatana castration (zvomusejari) kana GnRH analoginen vanoshingaira medicament dzinokurudzira kutora 50 MG kamwe pazuva.

Mabatirwo muiti ichi zvinofanira akatanga pavanoparidza negashiro GnRH analogue kana castration (zvomusejari).

In kenza yeprostate, munharaunda mberi vaiona zvinodhaka raitongwa pa 150 MG kamwe pazuva. Ya yokurapa pamwe mumiririri uyu anofanira kugara kwemakore anenge maviri.

With kuchiita hosha aine mahwendefa anofanira vakarega.

At vasingadzoreki itsvo nerevane zvemapapu chiropa dysfunction chipimo chemushonga kuchinja kunodiwa. In vanhu vane zvakakomba uye svikiro zvirwere zvakawedzera kuunganidza bicalutamide kunogona kuonekwa mune chiropa.

ipa zviitiko

Pane divi migumisiro yacho "Bicalutamide" chinodhaka? Mirayiridzo yokushandisa kuratidza zvinotevera divi siyana:

• gynecomastia, "Maze" ropa kumeso, zamu unyoro;
• manyoka, cholestasis, kuda kurutsa, jaundice, kufuta, kuvaviwa, alopecia, kurukutika, pabonde dysfunction, ungaderedza zvepabonde nemotokari;
• angioneurotic edema, abdominal marwadzo, mapundu, angina, interstitial zvemapapu chirwere, cardiac arrhythmias, kuora mwoyo, hematuria, dyspepsia;
• kurutsa, chiropa kukundikana, ganda kuoma, thrombocytopenia;
• kupatira, mwoyo kukundikana, kudya dysphagia, muromo yakaoma, flatulence, dyspepsia;
• dzungu, kupfupika mweya, nomusoro, hope, kushaya hope;

• nocturia, kupererwa neropa, Urinary turakiti utachiona, Urinary chengetedzo, dysuria, leukopenia, kuita weti kakawanda, hydronephrosis, polyuria;
• mapundu, hyperglycemia, wakawedzera vangadikitira, vakawedzera basa "chiropa" transaminases, hirsutism;
• marwadzo mudumbu, musana, muchipfuva, pelvic nharaunda, kuzvimba, vakawedzera kana ungaderedza muviri uremu, fivhiri, chirwere cheshuga.

Mari zvinodhaka uye kugadzirira zvakafanana

Price vaiona mushonga zvinogona yakasiyana Pharmacies siyana. Avhareji ukoshi mahwendefa 30 (50 MG) "Bicalutamide" yemakomo 590-830 rubles kuti kavha. Kana iwe kutenga zvakafanana zvinodhaka, asi pane imwe chipimo chemushonga pakati 150 MG wenyu kubhadhara kumativi 1100-1400 rubles.

Panyaya yakafanana Saka ivo zvinosanganisira zvinotevera mishonga: "Bikalan ',' Casodex ',' Bikulid", "Bilumid", "Bikalutera", "Kalumid", "Bicalutamide Canon". Mirayiridzo Kushandisa zvinodhaka izvi zvingave akasiyana "Bicalutamide". Naizvozvo, vanofanira kugadza chete ane ruzivo nyanzvi.

Anodzokorora nyanzvi uye vatengi pamusoro mushonga

Varwere vakawanda kusiya nzvimbo kupa wongororo chete akanaka. Maererano nenyanzvi uye vatengi, vachitora pokukurukura zvinodhaka akatsiga kanganwiro.

Kana zvinhu zvisingafadzi, ipapo anotaura varwere kuvapo vakawanda nemishonga. Kazhinji, negashiro mishonga yakadaro kunowanzokonzera abdominal marwadzo, simba, jaundice uye kuderedzwa hemoglobin. Uyezve, varume vakawanda vanotsutsumwa pamusoro kudhura mahwendefa. Kufungisisa kuti vanofanira kutora makore anenge maviri, mishonga kenza yeprostate zvinodhura chaizvo.