"Alfacalcidol": mirayiridzo kushandiswa, kusunungurwa chimiro, ongororo, mapikicha, chipimo chemushonga, analogs

Kushaikwa vhitamini D3 kukonzera matambudziko akakomba. Nokuti vana dhefisiti ichi hwakazara pokumuka kusimba, nepo mune vakuru kungava kusava chikonzero osteoporosis uye matambudziko zvakafanana.

The ano musika of Medicine anopa vatengi ayo zvakawanda mishonga wokubvisa kusakwana vhitamini ichi. Imwe mishonga yakadaro "Alfacalcidol." Mirayiridzo kushandiswa ndozvavava ive inobudirira zvinoreva normalize ari vhitamini-chicherwa mwero.

pharmacodynamics

medicament Iri vhitamini D3 kushingaira chimiro. Murau waJehovha kupanana inokosha chicherwa yeimwe, akadai phosphorus uye calcium, uyewo chinokosha mushonga "Alfacalcidol." Kushandisa zvinodhaka riri abudirire mutange mapfupa inotungamirwa. In yayo yakananga kubatanidzwa zvakawedzera Absorção de Água calcium phosphorus iri ura uye itsvo. Uyezve, mushonga uyu anowedzera pfupa chicherwa arambe achirema uye panguva imwecheteyo kunoderedza padanho tigutsikane muropa PTH. Somugumisiro, "Alfacalcidol" rine antirahitichnoe matambudziko uye kunobatsira kuderedza uwandu mitswe.

Kana mushonga kutora kosi, ipapo pasi pesvedzero yake nani kufambisa, akaderedza pfupa uye tsandanyama marwadzo (inova mhedzisiro rwakavhunika calcium-phosphorus muviri).

Mune zvimwe zviitiko, akaruramiswa kushandisa zvinodhaka?

"Alfakltsidol" mirayiridzo kushandiswa uye kutungamirirwa nenyanzvi dzokurapa akakurudzira taurira muzviitiko apo nhoroondo mashoko osteodystrophy, chisingaperi renal kukundikana rwakazara. Uyezve, rinoshandiswa mune hypoparathyroidism. Chikonzero ndiro chinangwa kusimba, osteomalacia (rwakapetwa rutapudzo remafupa rinenge) uye mapfupa kunyoroveswa, hunhu izvo zvingave zvakasiyana chaizvo. Osteoporosis - a steroid, penga nokuda kokuchembera, postmenopausal - uyewo vakabudirira kubatwa "Alfacalcidol" zvinoreva.

Tsika agadza mushonga ari zviitiko apo murwere kutambura kubva renal acidosis, kana nhoroondo ine Fanconi syndrome (kunzwisisa chirwere, kusanganisira renal acidosis, akatakura nhaka, nephrocalcinosis, kusimba uye zvichida hypophyseal urwere).

Nezvinetso zvose izvi, "Alfacalcidol" kubatsira kunobudirira.

Kana haafaniri kugamuchira?

The mazita contraindications kuti mushonga rine "Alfacalcidol" mirayiridzo Chinyorwa. Reviews nenyanzvi rambidza achitora mushonga ane nhoroondo mashoko hypercalcemia, hyperphosphatemia (kunze kana kukura hyperparathyroidism), gipermagnemii. Usashandisa zvinodhaka izvi kana kudhaka ane muviri chokuita kunyanya zviri vhitamini D3. Hazvina kunaka kuti ndipe "Alfacalcidol" ukoti mums.

Eya, sezviri pachena haukwanise kutora mishonga vanhu vane nomumwe hypersensitivity kuti zvinodhaka zvinoriumba.

Mafomu uye chipimo chemushonga

Mashoko akawanda zvakakwana sei kushandisa uye rine dosing nokuda zvinodhaka "Alfacalcidol" mirayiridzo Chinyorwa. Product chimiro (capsules pakati 0.25 MG kana 1), asi dose uye paanowedzera kuchirapa kosi chiremba vakasarudzwa nomumwe zvichienderana kwokuomerwa murwere ezvinhu uye yezvakaita chirwere.

Somuenzaniso, mukuru varwere kusimba, kukonzerwa kushayikwa vhitamini D3, nezvinetso nemudumbu, vanofanira kugamuchira kuti zuva iri dose yakawanda 1 kusvika 3 MG. A yakanaka mugumisiro pamwe kurapa nokuda hypoparathyroidism pasi kubva 2 kusvika 4 MG zvinodhaka pazuva. Daily vhoriyamu panguva kukundikana uye renal osteodystrophy basa haafaniri kupfuudza uwandu medicament 2 microgram. Fanconi chirwere uye renal acidosis zvinobudirira pasi aibatwa "alfacalcidol" murefu kugamuchira zuva dose ari Vhoriyamu 2.6 micrograms. In pamberi varwere hypophosphatemic kusimba uye osteomalacia inoshanda daily chipimo chemushonga mari ingabva 4 20 micrograms.

Doctors dzinorumbidza kutanga kurapwa pamwe yakadereresa dose, zvakananga mumwe chaiyo chirwere. Marapirwo inofanira kuongororwa mukati muplasma zvinhu zvakadai calcium phosphorus (kanenge 1 nguva muvhiki). Chipimo chemushonga "alfacalcidol" bvumidzwa kuwedzera hakuna zvinopfuura 0.5 micrograms pazuva. Kana shoma inobudirira chipimo chemushonga akawanikwa, zviri calcium muropa kunofanira haidereri kuzvidzora pane zvose 3-5 mavhiki.

sadikanwa migumisiro

Kufanana mishonga ipi, pane ndandanda nemishonga uye rinoreva "Alfacalcidol." Mirayiridzo yokushandisa (zvakafanana, sezvinei, vanewo zvimwechetezvo) rinopa pfungwa varwere kuti mushonga anogona sei kune zvomudumbu hurongwa. Kazhinji, kuda kurutsa, kurutsa, epigastric kurwadziwa, kupatirwa kana manyoka, chirungurira, kunzwa kuoma kwezvinhu mucous membranes pamuromo. Anogona kuonekwa neanorexia.

CNS nemishonga zvingaitika vakawanda simba uye Hope, kurukutika, nomusoro uye dzungu. Dzimwe nguva varwere vanoti pamusoro kukura tachycardia (nokukurumidza kwemwoyo) uye kuwedzera BP. Dermatologic siyana anogona kuitika sezvo kuvaviwa uye rashes paganda, kwete nyanyisa chaizvo kukura pfupa, tsandanyama uye vadyi nokurwadziwa. Dzingasiyana zvishoma rabhoritari netsika kune zvakawanda mukuru arambe achirema lipoproteins. Pane mukana hypercalcemia, hyperphosphatemia (avo achitambura abnormalities vari kushanda itsvo).

Kunwisa mishonga

A nhamba yakaipa mananara chichachengetwa muna chiitiko kuti vakapfuura bvumidzwa kuti zvinodhaka "Alfacalcidol" chipimo chemushonga. Mirayiridzo dzokushandisa zvokungwarira varwere pamusoro pangozi yokuita hypervitaminosis D. Early ovhadhozi zviratidzo zvinokonzerwa hypercalcemia. Kubva chakajeka kunoratidzei chero zvinoita gastrointestinal siyana, tsandanyama marwadzo, mumwe esimbi kuravira mumuromo, kuneta.

In chisingaperi kudhaka varwere dzinoshuma hope uye musoro zvingaitika muutera, kushatirwa, kushaya hope, ndangariro vanotaura, uye zvishoma kuwedzera BP. In murwiyo ropa dzimwe nguva ine residual yakawanda senitrogen uye creatinine. Pane mukana conjunctival hyperemia, calcification kuti itsvo, bapu, nyoro zvinyama uye ropa nemidziyo, inotungamirwa pamusoro concretions mu neitsvo. Pane aigona kuva nematambudziko nenzwi (hoarseness).

Kubvisa migumisiro ovhadhozi pamusoro mishonga inofanira ubviswe, dumbu kuwacha, kuronga, zvichienderana zviratidzo loop diuretics, bisfofonaty, hemodialysis kushandisa pasi pfungwa mhinduro calcium.

Kuitwa mushonga

Kune vakawanda zvirwere umo zvakafanira kutarisira "Alfacalcidol." Mirayiridzo dzokushandisa vari akakurudzira kunyatsoongorora kurapa mamiriro avo utano varwere vanenge atherosclerosis, sarcoidosis (kana mumwe mhando granulomatosis), pulmonary tibhii (active Danho), mwoyo nokukundikana uye renal insufficiency basa (chirwere fomu). Chenjerera ratidzai "Alfacalcidol" kana murwere nefrourolitiaza zviratidzo. Children uye varwere vakwegura uyewo vari pangozi (ekupedzisira chinodhaka aigona kupa zvakasimbisa kukura atherosclerosis).

Pregnancy uye lactation

Kana vakadzi vane pamuviri uye ekukurerai, ari "Alfacalcidol" mirayiridzo kunoita kushandisa chete zviitiko apo akatarisirwa nemigumisiro yakanaka nokuti mai kudarika pakaoma kuti utano nomwana uye kubudirira.

Hypercalcemia muna amai vanepamuviri, kushatiriswa-refu kushandiswa "alfacalcidol," anogona kupa achapesana kukudziri- nhamba matambudziko ari mudumbu. Pakati zvakakura nezvirwere mwana asati aberekwa anogona kunzi hypersensitivity kuti vhitamini D, kudzvinyirirwa kushanda parathyroid shwanu, kutsemuka stenosis, retardation mupfungwa, chaiyo elfopodobnoy panze syndrome.

Uyezve, "Alfacalcidol" mu bhuku duku anokwanisa panguva lactation yabudiswa muna mukaka. Kuti tidzivise ngozi hypercalcemia zviratidzo ari mwana, zvakakosha kuti zvakanyatsorongwa kutora mishonga nokungwarira.

Kudyidzana nevamwe zvinhu

"Alfacalcidol" User Application yakarumbidza haana kugamuchira kufanana anticonvulsant (barbiturates, phenytoin, uye zvichingodaro. D.) Tichifunga kuwedzera ayo ( "alfacalcidol") muviri. Nevakomana simba FIs. Pokushandisa medicament pachiimbwa vamiririri ane Digitalis, kungakonzera kugadzira arrhythmias.

Sezvineiwo zvinoderedza Absorção de Água "alfacalcidol" iri zvakafanana kuti kubvuma wayo sealbumin, antacids, mafuta chicherwa, colestipol, colestyramine, sucralfate.

Tikafunga magnesium tubhokisi laxatives kana antacids, anowedzera mukana wokuti gipermagniemii kana giperalyuminemii. In nokushandisa "alfacalcidol" ne mishonga, kuva kwayo sezvamunoita vhitamini D kana nomukaka ayo, kunowedzera mukana hypercalcemia.

Chepfu migumisiro "alfacalcidol" iri zvinooneka wakaderedzwa mu kufanana nayo kushandisa tocopherol, ascorbic asidhi uye pantothenic acid, thiamin, riboflavin, vhitamini A. The mugumisiro dzokuteerera "alfacalcidol" iduku raidudzwa pamberi nomukaka uye etindronoy pamidronic acid, glucocorticoids, kaltsitona. Uyezve, zvinodhaka izvi zvinoita Absorção de Água kuti phosphorus tubhokisi zvinhu, izvo kunowedzera ngozi yokuva hyperphosphatemia.

zvinodhaka zvakafanana

yainyanya kuwanika nokuti zvinodhaka "Alfacalcidol" analogues iri mishonga pamusika munyika. Mirayiridzo kushandiswa chine ruzivo pamusoro inonyatsobudirira vaya. Izvi zvinosanganisira mishonga "Etalfa", "Alpha-D3 din email", "Ca-Alfadol", "Alfa-Wang", "Oksidevit", "Tevabon".

Izvi zvinodhaka vagadziri kupa vatengi vari zvakasiyana-siyana: mahwendefa uye gelatin capsules, anosiya uye upfu, negadziriso intravenous aizomupa.

Reviews kugadzirira "Alfacalcidol"

Chero mushonga une vatsigiri uye vavengi, sezvo ndozvazvakaita pamwe nekugadzirira "Alfacalcidol." Mirayiridzo yokushandisa, mapikicha varwere vari kugutsikana simba anokonzerwa pamusoro muviri, pachena vatengi kuti mushonga anogona yekudyidzana kuvandudza kunaka kwoupenyu hwomunhu ane nhamba zvirwere chokuita kushayikwa kwemavhitaminzi uye zvicherwa, kuti karusiyamu-phosphorus muviri. Uyezve, "Alfacalcidol" anogona kungoita kuvandudza mamiriro bvudzi uye zvipikiri, izvo kunokoshawo.

Vamwe varwere vari kugutsikana chokwadi kuti "Alfacalcidol" Hahugoni kutengwa pamusoro pamusika rakavhurika, sezvo kunoda mushonga kubva chiremba. Zvisinei, nyanzvi utano muri pfungwa kuti kugadzirira chakakura kudaro, uye havafaniri kuva nyore wose.