"Domidon": mirayiridzo kushandiswa, uye chii kuti

With dzichipfekeka kusagadzikana pakati zvomudumbu turakiti akatarisana vose. Kakawanda, kusagadzikana mune epigastric munharaunda inomuka nokuti murombo uye kukodzera muviri. Kuti uvandudze kugaya uye mhanyisa gastric Kuburitswa mu, gastroenterologists dzinorumbidza kutora chaiwo nzira. Mumwe wavo nezve mishonga "Domidon". Mirayiridzo kushandiswa, inofambiswa uye zvairatidza zvinodhaka ichi dzinoturwa pazasi.

Form, akafanana, zvinodhaka kavha

Medicament "Domidon" mirayiridzo inochengetwa kavha chakagadzirwa makadhibhokisi, kugadzirwa piritsi fomu. Vose vanoumba nyika domperidone, uye zvinhu zvakadai lactose monohydrate, povidone, chibage starch, microcrystalline cellulose, titanium dioxide, pregelatinized starch, magnesium stearate, yavaibvisa lauryl sulfate, polyethylene glycol 4000, hydroxypropyl methylcellulose kana sepifilm 752 Blanc.

In kutengeswa chivako ichi anoenda gandiwa masero.

pharmacology

Chii mushonga ichi se "Domidon" (Mahwendefa)? Mirayiridzo Use rinoti iri rinodhaka GI motility. Pfungwa dzacho kushanda rinotsanagurwa kukwanisa adzikatidza D2-dopamine receptors. Somugumisiro izvi kunowedzera ya peristaltic kufamba muna 12 tiperstnoj ura uye gastric antral nzvimbo. Uyewo Inowedzera kuti Kuburitswa mu pakati akati nhengo uye anowedzera mataurire yegurokuro (rezasi sphincter).

mishonga iyi haina kumbochinja gastric secretion. Its Anti-emetic mugumisiro nokuda mubatanidzwa gastrokinetic zvazviri, uye daka kuti dopamine receptors vari chemoreceptor rukungiso nharaunda, izvo dziri kunze ropa-uropi nokuidzivirira. Uyezve, mushonga uyu anobvisa hiccups uye svoto.

kinetic unhu

Chii chakanangana kinetics zvinodhaka "Domidon"? Mirayiridzo dzokushandisa inoshuma kuti chokushandisa ichi nokukurumidza uye zvakazara woga kubva ura. It rinoita muna chiropa nemudumbu masvingo, kwamakadarika ane pasi bioavailability (kumativi 15%).

Neb gastric acidity muto uye kudya yekudyidzana sipidhi uye kuderedza Absorção de Água kuti domperidone. Parainge yeplasma wevasungwa yakawana awa rimwe pashure ingestion.

Kukurukurirana zvinodhaka kuti mapuroteni eplasma iri vanenge 91-94%. Zviri havaratidzi chinopinda kuburikidza BBB, asi anoita zvakanaka ari amai mukaka (padanho iri pamusoro 1/4 of zvachose wevasungwa muropa).

The zvipenyu Kushandurwa kugadzirira riri kuitwa N-dealkylation uye hydroxylation.

Nguva zvinodhaka hafu-upenyu maawa 7-10. In renal kukundikana (kwazvo), nhamba iyi ichiwedzera.

Rinobva mushonga kubva muviri pamwe mutsvina yadzo weti uye.

Zvairatidza kuti rubvumo

Mune zvimwe zviitiko, vakuru kunan'anura "Domidon" piritsi? Kushandiswa kwezvinodhaka ichi unoratidzwa kurutsa uye svoto uyewo kurwadziwa rokumusoro mudumbu, kunzwa zvizere uye chirungurira.

Sezvo vana, ivo vanoti kuti chivako ichi chete svoto uye kurutsa.

Contraindications

Kana kwete kushandisa mushonga "Domidon" (mirayiridzo kushandiswa uye nokuda akadini - zvose kuudzwa munyaya ino)? Contraindications venyika chokushandisa ichi ndiwo:

• gastrointestinal ropa;
• hypersensitivity;
• perforation of ura / mudumbu ;
• zvemaziso intestinal mhingaidzo;
• hypophysis bundu (prolactin-secreting);
• akabatana zvokuudzwa siyana "Erythromycin", "ketoconazole" kana zvimwe FIs kuti CYP 3A4, uyewo nevasori izvo kuwedzera penguva Q-T.

Drug "Domidon": mirayiridzo kushandiswa

Vaiona mapiritsi vanofanira chete kutorwa mukati pamberi zvokudya. Kana kugamuchira mushonga pashure kudya Absorção de Água kwavo zvishoma nomumugwagwa kwaitora nguva.

Vana makore 12 uye vakuru, mishonga iyi ushandiswe 10-20 MG katatu pazuva. Kufadza daily dose zvinodhaka rakanga 80 MG.

Ya chikuru kurapa - 4 mavhiki. Kana zvakakodzera, mamwe kushandiswa zvinodhaka riri kubvunza chiremba wako.

With kukura renal kukundikana vanofanira kuderedza multiplicity zvinodhaka. Panyaya chiropa kutadza, muchiitiko ichi, hazvina haungopiwi.

nemishonga

Ko kuonekwa nenjodzi mushonga "Domidon"? Mirayiridzo dzokushandisa akashuma kuti vakadaro nemigumisiro yei kuitika:

• kuwedzera prolactin mumatunhu;
• anaphylaxis ;
• kutya, kutambudza,
• edema, nezvishoma kuti chinguva Q-T, palpitations, dysrhythmia uye kwemwoyo;
• muromo yakaoma, extrapyramidal wenyonganyonga, nomusoro, nyota, kushaya hope, kushatirwa, dzungu, hope, lethargy, nokugwinha;
• gastrointestinal zvirwere;
• gynecomastia, galactorrhea, amenorrhea;
• kuvaviwa, dysuria;
• kuita weti kakawanda, ganda mapundu;
• stomatitis, conjunctivitis;
• asthenia, marwadzo makumbo;
• kuwedzera AST, alt uye remafuta akawandisa.

chaizvo kurumbidza

Chii chinofanira zvapinda murwere, usati kurongera mushonga "Domidon"? Mirayiridzo Use inotaura kuti chokushandisa ichi hazvigoni pamwe antisecretory uye antacid mishonga.

Nokuti kurapa vana pasi makore 12 ane uremu muviri makirogiramu asingasviki 35 vanoshandisa mishonga iyi hazvifaniri kuva.

Panguva mushonga chete zvinodhaka ichi haafaniri mugwagwa zvakanaka uye kushanda pamwe michina ngozi.

mutengi wongororo

Zvino kuti munoziva zvinhu zviri chakanangana zvinodhaka "Domidon". Mirayiridzo dzokushandisa uye nokuda chii, hatina kuudzwa apa.

Vatengi Most kushandisa chivako ichi akashuma kuti zvinobudirira anobvisa chirungurira, hiccups uye svoto. Uyewo, kuti zvinodhaka zvinoita kuti nokukurumidza Kuburitswa mu mudumbu, kuderedza kunzwa waziya uye kusagadzikana kushoma.

The chete zvakaipira zvinodhaka uyu vakawandisa nemishonga.