"Monosan": mirayiridzo kushandiswa, dzomuzana chaiwo

Sei uye chii chipimo chemushonga ushandiswe mushonga "Monosan"? Mirayiridzo Kushandisa vasodilator zvinodhaka inorondedzerwa zvakadzama zvinhu ino. Uyewo Rine medicament analogs, ayo akafanana, pharmacological zvinokonzerwa, contraindications, marwadzo, uye zvichingodaro. D.

The chimiro, kavha, akafanana

Ndezvipi zvinhu zviri chikamu zvinodhaka "Monosan"? Instruction inoti kuti mamiriro vanzwe kwezvinodhaka izvi isosorbide-5-mononitrate. Uyewo, kuti medicament unotora munhu sezvamunoita uye adjuvants akadai: talc granulated lactose, magnesium stearate, microcrystalline cellulose uye chibage starch.

In ipi vagadziri kubereka zvinodhaka "Monosan"? Mirayiridzo dzokushandisa rinoti kuti mushonga inogona kutengwa chete dziri mahwendefa. Vane chena uye kumativi ari chimiro. Kune rimwe divi hwendefa pane mukana.

The mushonga ari mumapepa mu Maronda akasiyana, izvo dziri mune wemagazini makadhibhokisi.

pharmacological zvinhu

Sei mushonga "Monosan"? Mirayiridzo yokushandisa kunoratidza kuti mushonga uri peripheral vasodilator, izvo anoita achinyanya pamusoro venous midziyo.

The medicament anokwanisa zvinowedzera kugadzirwa vascular endothelium endothelial vakazorora chinhu chakadai senitrogen oxide. Somugumisiro akadaro anokonzerwa ndiyo activation pamusoro soluble guanylate cyclase (intracellular enzayemu) kuti roga kunowedzera vasodilating murevereri - cyclic guanosine monophosphate.

Mushure kutora mushonga mukati masero kunoderedza myocardial okisijeni kudiwa. Izvi imhaka vasanyanye kuita uye post-preload.

Uyewo, vanachiremba havana vakanyorwa raidudzwa zvazviri koronarorasshiryayuschee mishonga a.

zvinodhaka migumisiro

Ndezvipi zvimwe zvinodhaka ane ehupfumi "Monosan"? Kushandisa zvinodhaka izvi zvinogona kuderedza ropa riyerere kurudyi atrium, izvo yekudyidzana kunoderedza kumanikidzwa iri pulmonary riparadzirwe uye akazoita kwokuomerwa akaipa zviratidzo pulmonary edema.

Zvinofanira kucherechedzwa kuti pasi pokudzora "Monosana" munzvimbo dzine murombo kuparadzirwa pane redistribution ropa kuyerera coronary

On pakanyorwa mushonga muvanhu vane angina uye ischemic mwoyo chirwere, yekudyidzana kunowedzera kuramba chero kurovedza muviri. Uyezve, nyaya mumiririri anokwanisa achideredza TX parameters Thrombocyte usage uye tunodzivisa platelet aggregation.

pharmacokinetic ehupfumi

Umo wefodya, akagovera uye rinoita zvinodhaka "Monosan"? Mirayiridzo application rinoti Zvakaitwa zvinodhaka fuma asi nokukurumidza uye zvakazara woga kubva zvomudumbu turakiti. Pashure pokugamuchira Mahwendefa antianginal chaizvoizvo akanga aona pashure anenge 30-45 maminitsi uye inotarisirwa kwemaawa 10.

Maererano nezvokurara, zvinodhaka "Monosan" ane kumbonyanya yakakwirira mwero bioavailability (dzinenge 99-100%). Izvi imhaka kusavapo wokutanga vanopfuura zvinodhaka kuburikidza hepatic hurongwa.

The hafu upenyu zvinodhaka ndiko maminitsi 60. Wevasungwa zvinodhaka muropa dzinosiyana zvishoma, kuchitsamira pamunhu.

Muviri kwezvinodhaka vanoshingaira fuma iri chiropa. Somugumisiro metabolic pezvakaitwa vari kuumbwa zvitatu zvinoti: isosorbide glucuronide uye vaviri isosorbide-5-mononitrate.

nguva hafu-upenyu maawa 4-5. Apo 2.2% iri yabudiswa nomukombiyuta renal maitiro uye 97,8% - sezvo glucuronic metabolites.

zvairatidza

Under chii ezvinhu zviri basa "Monosan"? Kushandiswa mishonga iyi zvinonyatsoshanda zvinotevera nyaya:

• pulmonary neBP, pulmonary mwoyo;
• chisingaperi siyana congestive mwoyo kutadza;
• Kudzivirira stenokardicheskie kuti pfari vari vanhu vane coronary tsinga chirwere.

Contraindications

Under chii zvinhu hazvigoni kushandiswa "Monosan"? Analogs akati zvinoreva pacharo chinorambidzwa kutorwa kana:

• vascular dhirika;
• ezvinhu nehana;
• arterial hypovolemia uye hypotension;
• cardiac tamponade ;
• vakasiya ventricular kutadza uye pasi indices rimwe diastolic BP;
• chepfu pulmonary edema;
• chenjera chokutambudzika myocardial infarction (pamwe raidudzwa hypotension);
• chimiro-kuvhara yemaziso;
• achiyamwa;
• zvirwere kuti kutsamwisa kuwedzera intracranial kumanikidzwa;
• nomumwe hypersensitivity;
• muvana uye kuyaruka (kusvika zera ruzhinji).

Zvinofanira kucherechedzwa kuti nhau zvinoreva kune hama contraindications. Zvinotevera ezvinhu zvinoshanda kwavari:

• mitral stenosis ;
• constrictive pericarditis;
• kukwegura;
• vascular zvinetso orthostatic murau;
• renal insufficiency hurongwa;
• hypertrophic cardiomyopathy;
• hyperthyroidism;
• hepatic kukundikana ;
• kutsemuka stenosis;
• zvakakomba kupererwa neropa mukati.

Drug "Monosan": mirayiridzo kushandiswa

INN (International Nonproprietary Name) mishonga iyi unorira "isosorbide mononitrate." mushonga uyu chinotarisirwa nomuromo chete. Maererano mirayiridzo, zvinofanira chimedzwe rose akashamba pasi nemvura.

Mahwendefa vanofanira kugadza mumwe chiremba. Panguva iyoyowo anosungwa rokuongorora kwokuomerwa runotikurudzira chirwere murwere wake.

"Monosanom" Treatment rinotanga kugamuchirwa kunoreva 10-20 MG 1-3 kanomwe pazuva. With mazuva 3-4 yokurapa zvinhu zvinofanira kuitwa dosing zvaiitwa. Kana zvakakodzera, uwandu zvinodhaka yakawedzera kusvika 20-40 MG uye nokutora kaviri pazuva.

Zviratidzo ovhadhozi

Ndezvipi zviratidzo ovhadhozi kunogona kuitika kana murwere kugamuchira isiri mishonga "Monosan"? Mirayiridzo kushandiswa anoratidza zvinotevera zviratidzo: kuparara, kufenda, manyoka chirwere, dzungu, hyperpnoea, akatsvuka ganda, vacheche, dyspnea, tachycardia Reflex mavambo, nomusoro, pyrexia, lethargy, utera, ikawanda intracranial kumanikidzwa, ziso nenyonganiso, nezvipusha, muviri, kuda kurutsa, pakoma, vangadikitira, kurutsa.

Mukurapa zvirwere zvakadai anoshandiswa dzokuparira gastric lavage uye varayire enterosorbiruyuschee zvinoreva.

nemishonga

Anoita rwakashata zvinodhaka maitiro "Monosan"? Mirayiridzo yokushandisa (analogs ose medicament vanoonekwa pazasi) inopa kuti yakadaro zvinodhaka kungaita nezve muzvizhinji parutivi-anokonzerwa. We taura vamwe vavo;

• kurutsa;
• kutsva manzwiro pamusoro rurimi;
• muromo yakaoma;
• svoto;
• kupiswa;
• tachycardia;
• nitrate nomusoro;
• Flushing ganda ;
• dzungu;
• nemuumbi zvinoderedza BP;
• stenokardicheskie wakawedzera kakawanda pfari;
• Orthostatic hypotension ;
• hypersomnia;
• mupfungwa retardation uye motokari mhinduro;
• kuomarara;
• madzerere;
• nokuvumba shiviriro;
• dzakananga ganda rashes;
• exfoliative dermatitis.

Analogs zvinodhaka uye mutengo wayo

Izvo zvinoreva unogona kutsiva mishonga «Monosan"? Analogues mishonga iyi inowanika ose chezvinodhaka. Pakati inonyatsobudirira zvinokwanisika govera "Monocinque raitongwa", "Izoket", "Kardiket", "Efoksa", "Pektrol".

Kana mutengo chinodhaka, hazvina yakakwirira chaizvo. Wana mushonga mumaguta Russian anogona chete 100s (Mahwendefa 30).

Testimonials

tiri kufunga mushonga une zvizhinji nyaya dzinovaka. Varwere vanoti kuti haazvibati somunhu inobudirira chaizvo mumiririri kuti pulmonary neBP uye chisingaperi mwoyo kukundikana chimiro. Zvisinei, zvinofanira kucherechedzwa kuti chokuwana dzakakwirira kuchirapa mugumisiro mumwe mushonga yakadaro inofanira kubatanidzwa nemamwe zvinodhaka. Kuti aite izvi, iva nechokwadi kuti kubvunza kuti kuenda kwachiremba.

Ini ndingadawo kuona varwere vakawanda kunofadza mutengo vakabvuma ne zvinodhaka. Sezvataurwa pamusoro apa, mapiritsi 30 unofanira kubhadhara rubles Russian 100 chete.

Hatigoni kutaura kuti pamusoro zvinodhaka uye kazhinji kusiya kunaka dzinovaka. Kazhinji, izvo chokuita nezve muzvizhinji parutivi-anokonzerwa. Panzira, kana zvaitika kubva ingestion anofanira kusiyiwa uye ne akachengeteka zvikuru rinoreva. Chii chaizvo, uchakwanisa kuudza chete ane ruzivo nyanzvi.