"Nexium": anogarasi shoma, mirayiridzo, maitiro. Nzira yekutora sei "Nexium"?

Munguva yedu, kurwara kwehutachiona hwepamuviri kunosangana kakawanda. Zviratidzo zvekurwara hazvisi kungokonzera kusuruvara uye kurwadziwa, asi zvinogona kutungamirira kumatambudziko akakomba. Murwere ane marwadzo munharaunda yepigastric, kuora mwoyo, kubata, kusagadzikana kwekudya. Kuti ubvise chirwere chacho, unofanirwa kuongorora chekuita uye kutanga utano. Inofungidzirwa kuva mishonga yakakurumbira uye yakakurumbira yekubvisa matambudziko emudumbu, "Nexium". Mirayiridzo yekushandiswa, uchapupu - humwe ruzivo runogona kuwanikwa kubva munyaya yacho.

Mhando yemagazini

Iyo mishonga ndeyeboka reAtPase inhibitors. Yakagadzirwa nenzira yepiritsi mu pink. Chinhu chikuru mumushonga ndeye esomeprazole pamusero we20 uye 40 mg. Zvikamu zvinobatsira ndezvi:

• Crospovidone;
• Glyceryl monostearate;
• Dye iron oxide machungwa uye tsvuku;
• Magnesium stearate;
• Microcrystalline cellulose;
• Macrogol;
• Titanium;
• Talcum powder.

Matafura ari muBlisters eAluminium, 7 zvidimbu chimwe nechimwe. Chigadzirwa chacho chakaiswa mukati mekutakura nemutambo wokutanga wokuvhara 1, 2, 4 blisters mune imwe neimwe. Nzira yekutora "Nexium", chiremba achataura mushure mekutanga kwehutano. Mashoko makuru achapiwawo pasi apa.

Action

Iyo huru yemishonga inonzi inoratidzika seyakakura ye omeprozole, inoderedza kushanda kwehydrochloric acid mukati mudumbu nekudzivisa zvakakwana proton pump mumapareetal masero. Basa guru rechirwere rinotarirwa mumaminitsi makumi matanhatu mushure mekutonga. Kutora mahwendefa kwevhiki paine 20 mg, iwe unogona kuona kuti inowanikwa nhamba ye hydrochloric acid muchivande chetachiva inoderera-mumuromo, kunakidzwa kunowanzoonekwa.

Kurapa kunobatsira kuburikidza nekudzivisa hydrochloric acid mukati me100% yevarwere mushure memwedzi maviri wemwedzi. Uyewo munguva yekurapa nekubvumirana kwemajoini nemishonga inorwisa mabhakitiriya, murwere ane kupedza kubudirira kweHelicobacter pylori wand, iyo inokonzera kusuruvara. Pamberi pekutanga kurapwa, murayiridzo wekushandisa unofanirwa kuidzidzwa kuNexium kugadzirira. Analogs ichava nemigumisiro yakadaro pamuviri.

Pharmacokinetics

Esomeprazole haikwanisi kurwisa mamiriro e-acidic. Nokudaro, mahwendefa aya akafukidzwa nefirimu chaiyo iyo isingazivikanwi nejusi jisi. Mushure mokushandiswa, mushonga wacho unokurumidzira unobatwa kubva mudumbu. Basa rayo guru rinopera mukati maawa maviri. Inenge 100% inobatanidza ne plasma mapuroteni. Kana iwe ukatora pamwe chete nemishonga, iyo nzira yekuita kwayo inoderedza uye inononoka mukati mudumbu. Izvozvo zvakanyanya metabolites zvechirwere hazvina matanho pane kuchengetedzwa kwepancreas.

Muchimiro chemetabolites, chirwere chacho chakanyanyiswa mumuguta, uye chikamu chiduku chete - nemasese. Muvatano vakwegura, metabolism haishandisi pakutora Nexium. Aifananidza anogue - "Esomeprazole" - ine pharmacokinetics yakafanana.

Zviratidzo uye zvinopesana

Mishonga inogona kurongerwa nokuda kwezvikonzero zvinotevera:

• Gastroesophageal reflux chirwere ;
• Kugadziriswa kwezvikonzero zvinokonzera reflux esophagitis;
• Kurapa kunotsigira varwere mushure mekuporeswa kwezvironda kuitira kudzivirira kuwedzera;
• Kurapa kwepaspic ulcers yemudumbu uye duodenum pamwe chete nemimwe mishonga;
• Matanho okudzivirira ekudzoka kwepisponda yakagadziriswa inosanganiswa nebhakitiriya Helikobakter Pilori;
• Yenguva refu yekurapa mushure mushure mekudya kwechingwa;
• Chirwere chinoporesa chinosanganiswa neNSAID administration;
• Pathological hypersecretion.

Contraindications:

• Kuvhiringidzika kune fructose, iyo inhaka;
• Kusakwana kwe sucrose uye glucose;
• Zera kusvika makore gumi nemaviri;
• Vana vezera remakore gumi nemaviri, kunze kwevatano vane chirwere chegastroesophageal reflux;
• Kugamuchirwa kwakaoma pamwe chete ne "Atazanavir" uye "Nelfinavir";
• Kuora kweiyo;
• Hypersensitivity kune chinhu chikuru - esomeprazole.

Asati yatanga kurapwa, zvinokurudzirwa kunyatsodzidza zvose zvinoratidza uye zvinopesana kuti chirongwa chekurapa "Nexium" chine. Analogues Russian zvakare inofanira kushandiswa mushure mekutaurirana nachiremba.

Dosage

Matafura anotorwa nemuromo, pasina kusvina uye kuchenesa nechingwa chemvura. Mushonga unofukidzwa nefirimu chaiyo iyo inopesana ne gastric juice. Bhebheti haigoni kutyorwa. Varwere ivavo vasingakwanisi kumedza mishonga yose, zvakakosha kuipedza hafu yegirazi remvura pasina gasi uye mushure mokunge nguva yekunwa. Kwekushandisa kwenguva refu, mushure mokunge chirwere chinoputika chinenge chichinjwa , 20 mg inorayirwa kuitira chinangwa chekudzivisa kudzoka zvakare. Mushonga unofanirwa kutorwa kamwe pazuva.

Panobata chirwere chegastroesophageal reflux, vanhu vakuru nevana vane uremu hwenyama zvinodarika 30 kg vanorayirwa mushonga pamutengo we 20 mg pazuva. Kana zviratidzo zvisingatongopedzi kwemwedzi, saka kumwe kuongorora kunodiwa. Mushure mekupora, munogona kutora mapiritsi sezvinodiwa kana zviratidzo zvikaitika. Chirwere ichi munyaya iyi chiri 20 mg kamwe pazuva. Varwere ivavo vanotora NSAID uye vari pangozi inobatwa nechironda chepamu, kunze kwokunge vaudza chiremba vanofanira kushandisa mushonga uyu "Nexium". Nhaurirano, kuongororwa - zvose izvi ruzivo rinofanirwa kujekeswa kusati kwatanga kurapwa.

Ne ulcer pathologies inobatanidza nebhakitiriya Helicobacter pylori, mushonga unoshandiswa sechikamu chetano yakaoma ye 20 mg pazuva. Mukuwedzera, amoxicillin (1 g) uye clarithromycin (500 mg) inorayirwa. Chiremba chakakomba chinoitwa kwemazuva gumi.

Nechinangwa cheAidri-suppressing therapy kune varwere vane chirwere chekudya ropa, chirwere chinorayirwa pamutengo we 40 mg pazuva nokuda kwemwedzi umwe.

Kuwirirana nemimwe mishonga

Iyo mishonga haina kukurudzirwa panguva imwechete nemishonga inotevera:

• "Ketoconazole";
• "Digoxin";
• Saxinavir;
• "Phenytoin";
• "Voriconazole";
• Warfarin.

Kana murwere akatora imwe yemishonga iyi, chiremba anofanira kuziviswa pamusoro peizvi asati atanga kushandisa Nexium. Mufananidzo unodhura unenge uine mazano akafanana.

Paunenge uchishandisa mushonga mukurapa kwepamusoro, murwere anogona kukura utera, kuora mwoyo uye zvimwe zviratidzo zvekudhakwa. Ikoko hakuna hutachiona hwemishonga. Naizvozvo, munyaya iyi, chirwere chinoratidzira uye chinotsigira chinorayirwa. Dialysis pano haibatsiri, sezvo chinhu chikuru chechirwere chacho chinoda kusvika 100% chinosanganiswa neropa reprotein.

Kuberekwa uye marariya

Kushandiswa kwe "Nexium" panguva yekuberekwa kwomwana kwakadzidzwa zvishomanana. Inogona kuongororwa mumatambudziko akasiyana, apo avo vanotarisira kubatsiririra amai vakamirira vakuru kudarika ngozi ye fetus. Maererano nemigumisiro yezvidzidzo zvemhuka, pakanga pasina kuipa kwakashata pane embryo, iyo inogona kukuvadza kusagadzikana kana kusagadzikana. Panguva yekuyamwisa zviri nani kurega kushandisa mushonga. Mishonga inopinda mumukaka. Kana pane chido chekurapa, zvinokurudzirwa kuramba lactation.

Kana iwe ukatora mushonga wacho nenzira isina kunaka, zviratidzo zvinotevera zvisingafadzi zvingaitika:

• Izvo zvinokonzerwa nekugadzirisa zvinokonzera, kusvika kuanaphylactic shock;
• Dhizinesi;
• Migraine;
• Pain epigastrium;
• Utsi hwakasimba;
• Kurara kukanganisika;
• Kunyarara;
• Imhaired renal function.

Kana uine mimwe migumisiro, udza chiremba wako. Nzira yekutora "Nexium" kuti urege kunyanya kudarika, chiremba achakwanisa kuudza pakagamuchirwa.

Special instructions

Mushonga unofanirwa kuchengetedzwa kure nevana, pamusana wekushisa kwete kudarika 30 degrees. Isosikiti inosunungurwa pamutemo. Hazvikurudzirwi kupa vana pasi pemakore gumi nemaviri, kunze kwekuda kwerapi ye gastroesophageal reflux chirwere. Kune varwere vane kukundikana kwakanyanya kwechirwere, chirwere chemishonga hachifaniri kudarika 20 mg pazuva.

Mune nzira yekurapa, zviri nani kusaisa motokari nebasa zvine chokuita nekufungisisa. Chizivi chinowanzoitika nekuda kwekutora mapiritsi. Chirevo chekutanga chinofanira kudzidzwa kune "Nexium" chishandiso. Idzodzo dzinoratidza kuti migumisiro yakawanda inowanzoitika mune varwere vanoregeredza mazano.

Anogeredze anogue - the drug "Esomeprazole"

Mishonga iyi ndeyeboka rinopesana, inhibitor yeproton pump. Uyezve, chinhu chinoshanda chinoderedza kuchengetedzwa kwehydrochloric acid. Chiitiko chakanaka chinowanikwa kakangopfuura awa mushure mekutora 20 kana 40 mg yemishonga. Kana iwe ukatora mishonga zuva rega rega kwemazuva mashanu, unogona kuderedza huwandu hwehydrochloric acid ne inenge 80%.

Mushonga wacho hauna kugadzikana kune midzi yechirungu. Nokudaro, granules uye mahwendefa akaputirwa nehupfeko chaihwo inogona kuwirirana nekuvhara gastric. 98% yezvinodhaka zvinosungira ropa reprotein. Izvo zvakaitwa zvinopiwa nemishonga "Nexium". Iyo yakaenzana yakafanana ye "Esomeprazole" inenge isiri yakasiyana pane yakagadzirwa.

Zviratidzo uye zvinopesana

"Esomeprazole" inogona kurongerwa munyaya dzinotevera:

• Kucherechedza kwekuita sophagitis;
• Matanho ekuchengetedza mukati maive atoreswa kurwisa reflux esophagitis;
• Chiratidzo chokurapa GERD ;
• Mukubatana nemishonga inorwisa mabhakitiriya kuuraya bhakitiriya Helicobacter pylori, iyo inokonzera chironda cheponda uye cheodenal ulcer.

Contraindications:

• Hypersensitivity kumushonga;
• Kuberekwa;
• Lactation;
• Nzira yakakomba yeinso kusakundikana;
• Zera kusvika makore gumi nematanhatu.

Ungatora sei mushonga?

"Ezomeprazole" inotungamirirwa nomuromo. Nhamba yakagadzirirwa mumwe nomumwe, ichifungisisa kuoma kwechirwere. Kazhinji, iri 20 kana 40 mg kamwe pazuva. Bhebheti haigone kudzingwa uye kupwanyika. Iyo yakafukidzirwa nehupfeko chaihwo inobatsira chirwere ichi kuti chigone kupinda mudumbu. Kana pasina kukwanisa kumedza mishonga yose, zvino inogona kuputika mugirazi remvura yakadzika kana yakabikwa uye mushure memaminitsi makumi matatu kunwa.

Neine renal pathology, chirwere chacho chinoshandiswa pamwero we 20 mg pazuva. Shanduro yekugashira pairi "Nexium" yakafanana. Analogues dzinodhura kakawanda dzine mazano akafanana.

Zvikanganiso

Kana chigadzirwa chacho chiri kutarisirwa zvisina kukodzera, zviratidzo zvinotevera zvisingafadzi zvingaitika:

• Headache;
• Dhizinesi;
• Nausea;
• Utsi hwakasimba;
• Kurara kukanganisika;
• Allergic reactions;
• Kupopota, nezvimwewo.

Kuongorora nezvekugadzirira "Nexium" uye "Esomeprazol"

Vazhinji varwere vanoda kushandiswa kurapwa vachishandisa madhiragi aya. Mifananidzo yeRussia ine mutengo unodhura, iyo inoda kusvika makumi matatu nemakumi matatu emapuranga. Asi iyo yepakutanga inotanga inotakura ine mari yakakwirira (anenge 800 rubles). Maererano nevarwere, hapana misiyano yakakura mumishonga iyi, saka hapana chikonzero chokubhadhara "Nexium". Mirayiridzo, zvakafanana, mari yavo - iyo yose ruzivo inofadza kudzidza, isati yaenderera kurapwa.

Mishonga yakatsanangurwa inotamiswa zvakanaka, munguva pfupi iwe unogona kubvisa marwadzo, ayo anokonzerwa nehuwandu hwehydrochloric acid muyamu yegastric. Vanobatsirawo kuporesa chirwere uye kwete kukonzera kudzokororazve. Mukubatana nemishonga inorwisa mabhakitiriya, murwere anobvisa helicobacter pylori bhakiteriya, iyo inowanzoita kuti gastric ulcer uye duodenal ulcer.

Chero bedzi nokurapa chiremba iwe unotanga kutanga kurapwa neNexium remedhi. Imwe inoshandiswa yakafanana ye "Esomeprazole" haifaniriwo kushandiswa yoga.

Izvo zvinoshanda zvinokonzera hazvikonzeri kukanganisa uye kubvisa zviratidzo. Matafura anokwanisa kutora. Iine shell, iyo isingakonzeri kushungurudzwa kwemucosa mudumbu uye inobatsira chirwere ichi kuti chikurumidze kupinda. Pahwendefa rimwe nerimwe (mararamiro avo ari pini) kune chiratidzo kubva kune akagadzira, icho chinodzivirira mishonga kubva pakugadzirwa. Vakawanda gastroenterologists mumutambo wavo vanoshandisa "Nexium" uye inoratidzika seanogue - mishonga "Ezekeprazol" - pakurapa zvirwere zvemudumbu zveEtiology yakasiyana. Nyanzvi dzinocherechedza kuti mishonga inotsanangurwa pamusoro apa inoratidza zvechokwadi chibereko chakanaka cherapi.