The mushonga "Topamax": mhinduro wevarwere uye vanachiremba

Inoshanda kana mushonga kwakadaro, sezvo "Topamax"? Reviews vanachiremba uye varwere zvichakurukurwa pazasi. Uyewo, uchadzidza pane basa zvinodhaka ichi anofanira kushandiswa uye izvo kuchirapa zvivako izvozvo kunoratidzwa.

The sezvamunoita, chimiro

In chii chimiro vari kutengesa zvinodhaka "Topamax"? Testimonials dzinoshuma kuti chokushandisa ichi inogona kutengwa muchimiro gelatin capsules, yakasimba chena.

The kushingaira wemafuta zvinodhaka ndiko topiramate. Uyewo kwayo sezvamunoita inosanganisira zvinotevera ebetsero zvinhu: shuga grits, povidone, uye cellulose acetate.

Kutengeswa zvinodhaka "Topamax" (wongororo vanachiremba nezvazvo vari zvakawanda chaizvo hunhu) anouya epurasitiki hombodo uye packs it kuti makadhibhokisi azvaitwa.

Zvinoitwa zvinodhaka

Ndezvipi capsules "Topamax"? Reviews akashuma kuti ichi antiepileptic zvinodhaka, iyo inesungano fructose. Its uchishandisa chaikosha kukwanisa tunodzivisa yavaibvisa migero, asi zvishoma kuchiita yokudzokorora. chiito potentials mu kwenguva refu depolarization pamusoro dzouropi masvingo.

Kugamuchirwa kusuma zvinoreva anowedzera basa γ-aminobutyric asidhi pamusoro mamwe neGhebha-receptors. Uyezve, vanoshingaira zvinodhaka inokwanisa ichivharira activation kuti kainate kuti glutamate receptors, uye waidzora basa neGhebha-receptors. Kwakadaro kuchirapa Migumisiro vari dose-chokuita zvinodhaka uye akacherechedza kuti kukosha kwayo muropa 1-205 micromolar.

Ndezvipi zvimwe zvivako zviri yo zvinodhaka "Topamax"? Reviews vanoti ayo chikuru chirungiso anokwanisa tunodzivisa basa carbonic anhydrase nhamba isomers. Zvinofanira kucherechedzwa kuti kwokuomerwa ari pharmacological zvivako zvinodhaka chaizvo muduku carbonic anhydrase FIs, kureva acetazolamide. basa rakadaro zvinodhaka hakusi chikuru chezvinonhuwira ayo antiepileptic chiito.

Kinetic zvechadenga gadziriro

Kana mishonga wefodya "Topamax"? Reviews vanoti pashure nokutora ichi kushingaira fuma zvinoreva nokukurumidza woga kubva ura. Saka bioavailability kuti topiramate rinosvika 81%. Kudya zvokudya hakuna kumbochinja chakarurama ichi.

Nokusungwa yezviri zvinoriumba zvinodhaka mapuroteni eplasma rinosvika 13-16%.

Kuti vawane zvakanyatsoenzana mune vanhu kwomuzvarirwo itsvo basa angada anenge 4-8 mazuva. Kushandurwa kaviri vanenge 20% of dose vakapiwa mari. Izvi unoumba metabolites nhanhatu (vakaneta).

Topiramate, uyewo zvose nomukaka yayo pacharo nokuda neitsvo. Zvichakadaro nguva yavo hafu-upenyu maawa 22.

Zvairatidza pakugamuchira somushonga capsules

Mune zvimwe zviitiko, varwere vari ushandiswe mushonga "Topamax"? Reviews ose migraine ndivo chete akanaka. Viewed kugadzirira rinoshandiswa kwete chete nokuda pakurapa akati chetsinga chirwere, asiwo dziviriro zvayo.

Zvinofanira kucherechedzwa kuti chokushandisa ichi kunoratidzwa tsime racho netsviyo. Rinoshandiswa kuti monotherapy vana kubvira pamakore maviri neari vakuru. Uyezve, "Topamax" rinowanzoshandiswa varumbidzwa kutora vanhu vane achangobva chirwere chepfari.

Senzira kunzwisisa mishonga zvinodhaka izvi zvinoratidzwa vana kubva varwere kukwana kana tonic-clonic generalized nezvipusha, uyewo nokuda pakurapa Lennox-Gastaut chirwere makore maviri okuberekwa uye vakura.

Contraindications kugamuchira somushonga capsules

Mune zvimwe zviitiko, haukwanise kutora capsules "Topamax"? Reviews (vana pasi pemakore maviri zvinodhaka izvi contraindicated) rinoti aiona zvinodhaka zvisiri kushandiswa Varwere hypersensitive kune yenhengo dzayo.

Nokungwarira yokunyanyisa inofanira kushandiswa mushonga uyu chiropa kukundikana, nefrourolitiaze, renal kukundikana uye hypercalciuria.

Dosing

Bvuma zvinodhaka "Topamax" anofanira kuzviita nomuromo. The capsules inogona kumedzwa wose, uye zvinokwanisika kuti kusanganisa zviri shoma zvokudya nyoro.

Nokuti kuzvidzora kuti tsviyo pfari kurapa yakarumbidza kutanga pasi kugamuchirwa medicament mishonga, uye ipapo titrated kusvika kwavo nyatsoshanda.

Apo tonic-clonic pfari uye chirwere Lennox-Gastaut zvishoma anobudirira dose zvinodhaka riri 200 MG pazuva. Mune zvimwe zviitiko, varwere kugamuchira vaifanira zuva dose kungaratidzwa akaenzana 1600 MG.

In vana zvavakabvumirana daily dose makore maviri ari 5-9 MG pa makirogiramu kurema muviri.

How kubata zvinodhaka vanofanira kubatwa pfari? Monotherapy vakuru ushandiswe 25 MG kamwe pazuva kwevhiki rimwe. Uyezve, nhamba iyi yakawedzera 25-50 MG pemavhiki 1-2.

Zvavakabvumirana chipimo chemushonga kuti monotherapy kuti nepfari muvana vaduku vanogona siyana vari kuwanda 100-400 MG pazuva.

Nokuti kudzivirira migraine zvinodhaka izvi zvinofanira kutora 50 MG kaviri pazuva. Kana zvakakodzera, kuti dose anogona ngazviwedzerwe (kusvika kutanga kurapwa kushanda).

divi-anokonzerwa hunhu

Viewed mushonga kunogona kukonzera zvakasiyana-siyana divi siyana. Most kazhinji kwakaratidzwa ndeinotevera:

• Hope, utera, dzungu, chakamira pakunodengenyeka zvine, kusakendenga, apraxia, zvemamiriro mafungiro, kukanganwa, havachanyatsogoni kufambisa, dystonia;
• kuvhiringidzika, vachidanidzira, anonoke mafungiro, aone zvinhu zvisipo, kuora mwoyo, ungaderedza libido, yokufara mwoyo, hasha siyana;
• neanorexia, pfungwa nomuviri zvemwana asati, gastritis, flatulence, dyspeptic zviratidzo;
• kurwadza kwacho, chinyamunhari chinorwadza, kuzvimba mapfundo;
• yaitsigira divi noupofu, presbyopia, conjunctival edema, uye vamwe.

Medicament "Topamax": wongororo

Pfari - chirwere chikuru umo zvinodhaka anopiwa nezvawo. Maererano nemashoko vanachiremba vane chirwere mishonga iyi haisi nguva dzose kuratidza zvakakwana kuchirapa efficacy. Uyezve, vatsigiri muzvizhinji kugamuchirwa divi siyana, kusanganisira chikamu tsinga uye psyche.

Kana varwere, ivo vanotaurawo kuvarombo tolerability zvinodhaka. Ndosaka vakawanda vavo kushandisa zvikuru kuwana mari ivo anokurudzira chiremba.

Hatigoni kutaura kuti mushonga mu mubvunzo zvinowanzodavirwa kushandiswa varwere zhinji senzira kuderedza uremu. Zvisinei, vanamazvikokota vanoti kana achitora capsules "Topamax" zvinangwa izvi zvinofanira kufungwa nezvazvo mukuru toxicity kwayo.