Amlodipine gwaro

Medicine "Amlodipine" zvichida yaizivikanwa vakawanda vomuzana ruoko. Zvikurukuru, mushonga uyu ushandiswe varwere angina. Ngatikurukurei zvinodhaka "Amlodipine" ane mirayiridzo ane ruzivo inotevera.

Zvinoumba. Mumwe piritsi (5 MG) yaiva basa fuma amlodipine besylate. Sezvo Excipients inoshandiswa lactose, mbatatisi starch, collidone, microcrystalline cellulose, magnesium stearate.

tsananguro General. "Amlodipine" Mahwendefa chena kana zvinenge chena maviri ane mativi rwakashodoka. Apo neapo chiedza vangave marbling.

Pharmacodynamics. Dihydropyridine rinobva - kutigumbura karusiyamu "anononoka" wechipiri-chizvarwa hova ine gipotezivnoe uye antianginal nemigumisiro. Chokuita dihydropyridine Kanotokonya uye anotakura blockade calcium migero, nokudaro kuderedza transmembrane ndima calcium ions kupinda muchitokisi (kuti mukuru zvakadini mune anotsvedzerera tsandanyama mudziyo masvingo kupfuura cardiac myocytes). Antianginal zvazviri kunokonzerwa rokuwedzera arteries uye arterioles iri arikunze: angina umenshaetsnizhaet kwokuomerwa myocardial ischemia, peripheral tsinga anowedzera, nokudaro achidzikisa zvachose vascular peripheral nemishonga, Kuwedzera kunobatsira kuderedza preload pamwoyo, kunoderedza kudiwa moyo okisijeni. In varwere angina, nezuva dose chete kunowedzera run nguva fiznagruzki, DZEMUNHU DZINODZORA kukura ischemia uye angina, ndinoiitawo zvose akazoita multiplicity kuti angina kurwiswa uye kudikanwa nitroglycerin. Saka, varwere angina inoda "Amlodipine" gwaro uchapupu ichi.

Pharmacokinetics. Pashure zvokuudzwa kwokubatsira mushonga zvishoma nezvishoma woga kubva nemudumbu. Mhedziso avhareji bioavailability ndiyo 64%, kupfuura kuramba muropa serum pashure pemaawa 6-9. Kugadzikana zvakanakanaka ropa kwakacherechedzwa pazuva 7th zuva. Food haadi kukanganisa Absorção de Água kuti amlodipine. In varwere vakwegura (vanopfuura makore 65) ari excretion zvinodhaka riri kunonoka zvichienzaniswa vechiduku, asi musiyano uyu haasi akaora chinokosha.

"Amlodipine" mirayiridzo ine zvose zvakafanira mashoko ane zvinotevera zvairatidza kuti application: kuti chirwere cheBP (akabatana nevamwe kana zvakafanana nzira monotherapy), exertional angina, vasospastic angina (Prinzmetal kuti angina).

Contraindications.

- matunhu aikanganiswa yezviri chirungiso nemamwe dihydropyridine nomukaka;

- hypotension kwazvo chimiro;

- cardiogenic kuvhunduka, kuwa;

- kusagadzikana angina (Kunze - Prinzmetal angina);

- lactation uye pamuviri;

- vanhu pasi pemakore 18 vakachengeteka uye kushanda vasina dzakatangwa.

The chipimo chemushonga uye nzira chikumbiro. Tora "Amlodipine" mirayiridzo anogovera sezvinotevera: mukati, shoma dose 5 MG, kufadza - 10 MG 1 nguva pazuva. Kana neBP dose yokuzvigadzirisa kunogona 5 MG pazuva. Kana shamhu akatorwa kamwe 5-10 MG pazuva. Varwere Mutete, uyewo varwere yakaderera uye varwere havachanyatsogoni chiropa kushanda raitongwa 2.5 MG.

Mirayiridzo Special. Munguva yawapiwa ne "Amlodipine" vanofanira kutevera uremu uye kudyiwa zvakadai zvinokuvadza sezvo yavaibvisa, dzimwe nguva zvinoda chaizvo kudya. Zvakakosha kutevera dzaiita zvokutaurwa utsanana uye meno, shanyira wemazino dzose (kudzivisa marwadzo uye nekudeura ropa mazino). By kuwedzera dose vakwegura zvinoda kungwarira kuongorora. Kubata zvinodhaka riri kukwanisa kutyaira motokari hapana mashoko. Zvisinei, zvinofanira kurangarirwa kuti mune dzimwe vanhu zvinogona kukonzera zvishomanana dzungu uye hope.