Antivirals

Antiviral zvinodhaka - zvinodhaka kuti vaite pamusoro nemavhairasi kuburikidza usachikanganisa hurongwa hwavo kana nyonganyonga chinokosha mabasa.

Parizvino dzakabudirira dzakawanda zvinodhaka zvakadaro zvakakwana. Vose dzinoiswa ne zvechadenga pharmacological zviito uye yakananga zvokurapa zvairatidza. Govera zvinotevera boka kuti antiviral yomuchipatara: kupararira chakarondedzera antiherpethetical, protivotsitomegalovirusnye, yokuSpain, Anti-retroviral. The zvakanakisisa anozivikanwa vamiririri wokutanga mhando zvinodhaka ndivo "ribavirin" uye "Lamivudine". zvinodhaka izvi vane nzira dzakaoma kuita, chokuita rutapudzo pakati nucleic acids nokusunga kuti makemikari ari utachiwana. Sezvo zita munda nokushandisa zvinodhaka izvi rakanyatsojeka paupamhi uye inosanganisira zvakawanda DNA - uye RNA tubhokisi nemavhairasi kuti kuti PC kuti urwere, fivha lasa, hepatitis C, uye AIDS.

zvinodhaka Antiherpethetical vanomirirwa mari mana, izvo avo morphological mamiriro nucleoside analoginen acyclovir, penciclovir, famciclovir, valacyclovir. Okupedzisira maviri chipimo chemushonga siyana vari vakaneta. Muvanhu, vari kutendeukira acyclovir uye penciclovir. Izvi zvinokonzera zvavo pedyo morphological uye histological zvivako.

The mashandiro chiito kuti acyclovir ari kudyidzana pamwe nemavhairasi makemikari, pakwakanga anokudimburira kukura kwavo kutenderera. Zvinoguma kuparadzwa nayo utachiona. kudyidzana uku inopiwa sechivako acyclovir, kuri analoginen dezoksiguanedina (purine nucleoside). Most inonyatsoziva zvinodhaka ndiko herpes simplex utachiwana. Kune utachiona zvigare izvo husingakwanisi zvinodhaka ichi. Izvi zvinogona kutsanangurwa nokushandisa immunosuppressive mishonga. The mashandiro kurwisa ndiwo mutation kweutachiwana enzayemu mugadziriro, kuchinja specificity zvinodhaka. Mune chiitiko ezvinhu akadaro zvinodhaka dzimwe pharmacological mapoka ( "Foscarnet"). Children antivirals zvinosanganisira "Valacyclovir." High bioavailability, inova vanopfuura makumi mashanu kubva muzana ndozvinoitawo zvinokonzera. Izvi zvinoreva kuti zvinoda mishonga duku zvikuru pamusoro zvinodhaka (kana ichienzaniswa "Acyclovir") kuti kuzadzisa sei.

The mashandiro chiito kuti penciclovir iri kushanda hapana chakasiyana kugadzirira veboka. Rinotaurawo anotyora kwetunhu DNKmikroorganizma. Zvisinei, zvakasiyana pakuti zvikuru kunokanganisa Varicella-Zoster utachiona (VZV).

By protivomegalovirusnym zvinodhaka zvinosanganisira "Ganciclovir", "Valganciclovir", "Foscarnet", "Cidofovir", "Fomiversen". Vane panzvimbo yakaoma mashandiro chiito, unosanganisira yemakwikwi chinovhiringidza DNA polymerase yacho microorganism. Mugumisiro nekuita uku ndiko contravention pakati elongation DNA cheni inotungamirira kurufu kwayo. zvinodhaka antiviral Most kuti kubvisa zviratidzo cytomegalovirus chirwere - zvinoreva ichi boka pharmacological. Zvisinei, kushandiswa kurapika pashure mazhinji zvingamuka, iyo yakati zvinoderedza kuwanda kwavo kushandiswa.

zvinodhaka Antiviral kunogona zvakananga nezvainoita immunodeficiency kwevanhu utachiwana. Naizvozvo, dzimwe Pharmaceuticals, iro rine zvakafanana nechiito, vasanganiswa yemaARV boka. Vose vane kunzwisisa mashandiro chiito inobatanidzwa blockage pamusoro enzayemu enyika muviri, ayo kuberekana kukanganisa.