Benzylpenicillin yavaibvisa munyu: mirayiridzo kushandiswa. chikumbiro mitemo

Munyaya ino tichataura pamusoro pekugadzirira akadai "Benzylpenicillin yavaibvisa munyu". Mirayiridzo yokushandisa, zviratidzo, chipimo chemushonga uye kurumbidza dzokushandisa ichashandwa munyaya. Uyezve, isu funga pharmacological ehupfumi zvinodhaka, zvingakonzerwa nemishonga uye zvinodhaka aiita vamwe mishonga.

kwadzo

The mushonga chinhu inorwisa utachiona mumiririri uye mushonga unorwisa zvaiva penicillin boka. Benzylpenicillin yavaibvisa munyu pacharo, mirayiridzo kushandiswa iyo zvichakurukurwa pazasi ari zvinoberekwa notumwe siyana.

Zvinodhaka muboka iri rinoshandiswa kuti intramuscular kutarisira kubatsira munyama siyana uye nhengo umo ropa anosvitsa shoma penicillin. Kuti mushonga akatanga kuva migumisiro pamusoro uropi uye musana uye meninges, subarachnoid dzakabatwa.

Benzylpenicillin yavaibvisa munyu, mirayiridzo kushandiswa: pharmacologically chiito

The mushonga unoshanda pamusoro giremu-zvakanaka utachiona, izvo zvinosanganisira:

• staphylococci;
• streptococci;
• pneumococci;
• diphtheria ;
• coli nechigwadara;
• Kurovedza (kupukunyuka pasina okisijeni) sporulating tsvimbo.

Uyezve, mushonga rinoshanda pamusoro giremu kunaka cocci (meningococcus, gonococcus), spirochetes, actinomycetes uye mamwe majemusi. Penicillin yavaibvisa munyu iri basa pamusoro nemavhairasi, rickettsiae, notumwe tupukanana majemusi.

Drug nemishonga okuva staphylococci, izvo vanokwanisa kubereka enzayemu penicillinase, kuparara benzylpenicillin. The medicament rinoratidza pasi mubasa pakurapa Pseudomonas aeruginosa, intestinal utachiona uye mamwe majemusi, zvinokwanisa kuita govera uwandu penicillinase zvakasiyana.

Pharmacokinetics

In intramuscular mushonga nokukurumidza anopinda muropa, kubva apo runopiwa muviri zvinwiwa uye munyama. Panyaya cerebrospinal fluid panoparadzana mwoyo kune shoma penicillin. The soro wevasungwa muropa mushure kutarisirwa kwaro intramuscularly kuchengetwa pashure 30-50 min. Kana mushonga raitongwa subcutaneously, mwero Absorção de Água ipfupi uye kufadza uwandu zvinhu muropa chichachengetwa neawa.

maawa matatu pashure jekiseni (subcutaneous kana intramuscular) kuti benzylpenicillin chete zvisaririra kuramba muropa. Naizvozvo, kuti tirambe yakakwirira wevasungwa zvinodhaka mumuviri kwenguva refu, zvakakodzera baya jekiseni kuburikidza maawa mana ose.

Kana achiita nomutsinga, ayo wevasungwa zvinodhaka nokukurumidza rinokundwa. Uye vachitsigira nomuromo benzylpenicillin rinoparadzwa penicillinase (enzayemu) uye gastric muto.

Yabudiswa chinodhaka yabudiswa muna weti.

umboo

Vanofanira kuva vainyatsoongorora pamberi kugadzwa mushonga sezvo kuti penicillin yavaibvisa munyu, mirayiridzo kushandiswa, chipimo chemushonga uye zvairatidza kuti kushandiswa. Ngatitange pamwe chechipiri. Saka, mushonga wacho ushandiswe:

• mu zvirwere mapapu uye kufema turakiti;
• zvakakomba septic zvirwere;
• kwemabhakitiriya endocarditis;
• sepsis;
• noutachiona uye mavanga utachiona kubva nyoro munyama, ganda uye mucous membranes;
• Unopisa;
• kuzvimba musana uye pfungwa, mazgovyh namatehwe;
• purulent pleurisy;
• peritonitis;
• cystitis;
• Pius uye septicemia;
• osteomyelitis;
• diphtheria;
• nezvitsvuku fivhiri;
• mwandabvu;
• erysipelas;
• Zvirwere vachangoberekwa;
• nechigwadara;
• njovhera;
• actinomycosis;
• siyana gynecological inflammations;
• anogumbura zvirwere huro, nzeve uye mhuno.

Terms of Use uye chipimo chemushonga

Zvichienderana mhando nechirwere mishonga kushandisa benzylpenicillin yavaibvisa munyu zvinodhaka anogona kupiwa. Mirayiridzo yokushandisa, nzira chourongwa uye inobvira chipimo chemushonga ichakurukurwa nesu muchikamu chino.

Yawapiwa zvinodhaka hunogara, zvichienderana chirwere, kubvira 4 vhiki kusvika 2 months kana zvakatowanda. The mushonga unogona kupiwa nenzira dzinotevera:

• Intramuscularly chokumusoro rokunze quadrant pamusoro gluteal. Kugadzirira rakasanganiswa pamberi rokutarisira mu kwakadonhera mvura, novocaine kana yavaibvisa chloride mhinduro.
• Intravenous - .. Only pasi zvirwere zvakadai zvikuru, zvakadai yomumuzongoza, kwemabhakitiriya endocarditis, septicemia, etc. The mushonga chinotarisirwa ose 4 awa kana kuramba donhwe - Madonhwe 30 paminiti kwemaawa 6-12.
• Inogonawo kupiwa endolyumbalno benzylpenicillin yavaibvisa munyu. Mirayiridzo dzokushandisa (kushandisa maitiro) inopa nzira nokuda kuzvimba uropi uye musana, kusanganisira meninges. The mushonga ari jekiseni zvishoma nezvishoma - maminitsi 1-2.
• Pane zviitiko apo benzylpenicillin inoshandiswa Kubayiwawo jekiseni racho anogumbura foci. Somuenzaniso, apo actinomycosis, ganda leishmaniasis, chisingaperi pyoderma nezvimwe zvirwere ganda rwarisa.
• With inhalations - nokuti mishonga uye kudzivirira zvirwere mumapapu uye Airways. Nokuti chinangwa ichi, hwakakanyiwa benzylpenicillin yavaibvisa chloride mhinduro kana kwakadonhera mvura. Inhalations hapana anopfuura 2 nguva pazuva. Inogara kurapwa - kubva 10 kusvika 30 maminitsi.
• Zvinonzi zvakare jekiseni kupinda pleural kana peritoneal mhango mu purulent peritonitis kana pleurisy.
• Muchimiro crow, mafuta okuzora, manyoro dressings, lotions uye Nezvakakuyiwa - nokuti kutsva, Maronda ari nyoro zvinyama, uye osteomyelitis unto.
• Uyewo, zvinodhaka mhinduro rakashandiswa pakurapa yokumusoro zvirwere zvokufema uye ophthalmology.

Penicillin inogona kushandiswa kurapa pamwe nemamwe mishonga uye sulfanilamide gadziriro. Pakazoti nzira achawedzera kuti mishonga mugumisiro nemishonga inoshandiswa.

nemishonga

Rinogonawo kuva inokanganisa kuti benzylpenicillin yavaibvisa. Mirayiridzo dzokushandisa anoti vari kunoratidzwa intravenous kwokubatsira mushonga unowanzosangana.

Zvikurukuru, kurutivi migumisiro chokuita neutachiona kuti zvinodhaka. Pakati rwakashata zviratidzo vakacherechedza:

• candidiasis;
• mikoko;
• fivhiri;
• nomusoro;
• chills;
• kurwadza kwemajoini;
• Angioedema;
• eosinophilia;
• -siyana dermatitis;
• fivhiri;
• lymphadenopathy;
• anaphylactic kuvhunduka - mune mashoma chaizvo nyaya.

Contraindications

Havasi varwere vose vanogona kutaura kurapa ane medicament pamusoro benzylpenicillin yavaibvisa munyu. Mirayiridzo yokushandisa uye mitemo chourongwa zvinopa zvinoverengeka contraindications. Pakati pavo:

• sema zvirwere zvakadai urticaria, nouswa, Árbol asima, etc.
• hypersensitivity kuti kuti penicillin nomukaka;
• kujairika mhinduro zvinodhaka;
• chirwere utachiona hwakakura kuramba kuti chikwata dose kuti benzylpenicillin.

Kutanga zvinodhaka endolyumbarnym anokwanisa hazvitenderwi mu netsviyo.

Pregnancy uye lactation

Kugadzwa panguva pamuviri chete kana zvinobatsira kuti kurapwa nevakadzi mukuru kuna zvingakanganisa mwana wake asati aberekwa. Zvikasadaro, mushonga hauna chinotarisirwa. pangozi reshiyo uye kunyatsoshanda iri pakutsvaga kupinda chiremba.

Kana zvakakodzera, kwokubatsira zvinodhaka panguva lactation ngaanyarare achiyamwa.

ehupfumi

Drug fuma benzylpenicillin yavaibvisa munyu ane chimiro chena yakaisvonaka crystalline upfu ane zvinovava kunaka iri nyore soluble iri mvura.

The mushonga ari nyore yakaparadzwa acids, alkalis, oxidizing vamiririri, enzayemu penicillinase, uyewo kudziyisa. Gadzirira zvinodhaka fuma zvinofanira pakarepo asati kutarisira.

matanho okudzivirira

The mushonga chinotarisirwa chete muchipatara nachiremba kuti mushonga uye pasi pokudzora yake. Nokufamba mushonga arangarirwe kuti kukwana dose benzylpenicillin kana mangwanani kugumiswa kurapwa kunogona kuti paumbwe nemishonga utachiona zvigare. Mune chiitiko kurwisa kuti kurapika iri mberi dzimwe inorwisa mabhakitiriya.

Muitiro neutachiona raitongwa pamwe antihistaminic kwezvinodhaka kuri benzylpenicillin yavaibvisa. Mirayiridzo yokushandisa (zviito mushonga wake ushandiswe kunyanya akadzama) anoudza kuti apo pakarepo murwere sema kuratidzwa kurapa amira.

In mamwe mapoka varwere (vakwegura, vacheche, simba chirwere) vangava kuramba benzylpenicillin hunokonzera kukura superinfection.

With kushandiswa nguva refu, kuti mushonga inogona woutsinye kana pamwe yakaparadzwa intestinal microflora, zvichitungamirira kwakaderedza kugadzirwa mavhitamini veboka B. Naizvozvo prophylactically varwere kazhinji ndishandise mavhitaminzi B1, B12, uye vamwe.

Kana, pashure kutanga kurapwa nokuti 3 mazuva haana akacherechedza zvainoita, zvakakodzera kuenda kurapwa kubatanidzwa kana kurongera idzva asingaurayiwi.

Zvokungwarira

Zvokungwarira basa vanhu vane mwoyo nokukundikana uye havachanyatsogoni itsvo mashandiro benzylpenicillin yavaibvisa munyu. Mirayiridzo dzokushandisa rinokurudzira kuti vainyatsotarisirwa chipiwe kune varwere vakaona hypersensitivity kune cephalosporins.

Nokuda mukana fungal superinfection inokurudzirwa kuti taurira Anti-fungal nevamiririri.

Kudyidzana nevamwe zvinodhaka

In kugadzwa nemishonga avo, vane bacteriostatic, bactericidal kuitwa kuti penicillin ipfupi.

Kugadzirira "Probenecid" ane pfuma kuderedza tubular secretion kuti mushonga kuti zvinoguma kuwedzera ropa pamwero yokuteverera, Somugumisiro, kuwedzera nguva achibvisa kubva mumuviri.