Digitalis gadziriro: zvairatidza uye migumisiro mu cardiac zvirwere

Digitalis - genus kuti maruva zvinomera, dzinoshandiswa mushonga zvinetso mwoyo.

About kardiotropnyh ehupfumi kuti ruva iri refu chakazozikamwa. In yokutanga yezana XVIII remakore, zvakatanga kukura Russia muna wezvinonhuhwira mapindu, uye kubva 1775, apo ivo dzakabudiswa mabasa British zvokurapa Uayteringa, Digitalis kugadzirira kunge zvakasimba raitika tsika yokurapa mwoyo zvirwere.

The botanical unhu digitalis

Rhode Foxglove (Digitalis) - Flowering zvirimwa vari perennial mhuri plantaginaceae makuru inflorescences ari thimbles dzakafanana maruva uye akatunhidzwa rakawunyana mashizha. Bloom pakati muzhizha (kuguma June-July), michero - rinopeta mabhokisi zai serin'i pamwe shava mbeu duku. naperstyanok Total akatsanangura nezvemarudzi 36 iyo inoshandiswa mukurapa zvinangwa chete 5: Digitalis lanata (chikuru tsime mbishi zvinhu), nezvishava, ciliated, uye grandiflora ora.

Pakutanga zvinodhaka Digitalis lanata aiva mushoma kubva Mashizha rokutanga uye rechipiri gore. Pari, Pharmaceuticals Digitalis glycosides vakawana kubva zvemuchadenga zvikamu zvinomera, mowed asati maruva.

uturu foxglove All, zvichiratidza kuti vakawanda pakugadzira vanoshingaira zvinhu uye kunoda kungwarira kukurukurwa.

Chemical zvinoriumba uye chikumbiro foxglove

Mishonga Digitalis zvinosanganisira wayo unorapa huru - cardiac glycosides: digitoxin, gitoksin, digoxin, atsetildigoksin nevamwe vazhinji, uyewo Organic acids, saponins, flavonoids.

Most vanoshingaira zvinoriumba vane mavambo hydrolytic chesekondari, i.e. yaunganidzwa enzymatic cleavage pamusoro mamorekuru sezvingatarisirwa kuitika glycosides.

Digitalis mishonga inoshandiswa pakurapa cardiac zvirwere zvakawanda, kunyanya chokuita vanotaura mumoyo uye ropa midziyo:

1. Mwoyo nokukundikana uye siyana Organic maronda mwoyo zvivako (kusanganisira kuzvidzivirira mwero).
2. Zvirwere zvomwoyo mavharuvhu zvichitungamirira decompensation.
3. Atrial fibrillation.
4. Kuzvimba uye degeneration mwoyo tsandanyama.
5. Paroxysmal tachycardia vakadzi vane pamuviri.
6. Kugadzirira cardiac kuvhiyiwa.

Kana kutyorwa kuri cardiac conduction hurongwa (misa) uye bradycardia Digitalis glycosides haana basa.

Sei zvinodhaka Digitalis glycosides

Kure uswa Digitalis glycosides chaizvo zvainoita pomwoyo. Mumoyo kukundikana, mugumisiro digitalis chikumbiro riri sezvinotevera:

• kuderera mumoyo zvazvingava;
• kuwedzera myocardial contractile simba;
• nezvishoma nguva dzokuzorora mwoyo (diastole).

gadziriro Digitalis dzave vakabudirira kushandiswa pakurapa kweropa kukundikana, kana mwoyo haakwanisi kubata kusimudzira nhumbi ropa, iro rakaoma nokuda edema uye trophic zvirwere. Muchiitiko chino, kubudikidza glycosidic zvinodhaka kutarisirwa:

• yakawedzera cardiac goho (uwandu ropa achibuda ventricles por rutapudzo);
• vanobudirira Kuburitswa mu pamusoro ventricles panguva systole;
• kuderera ropa vhoriyamu achiparadzira mumidziyo uye, naizvozvo, achidzikisa bundu;
• normalization nomwoyo exchange tachycardia;
• kumhanyisa ropa riyerere ari vascular pamubhedha;
• kuwedzera vascular matauriro, izvo pamwe zvishoma kuwedzera BP.

Digitalis toxicity anogona kutsamwisa pamamiriro divi anokonzerwa nokuvhiringidzirwa ari nemudumbu, tsinga, kwemwoyo kuchinja. Kunze komutemo Kushandisa zvinodhaka izvi nezvisingabvumwi, marapirwo zvaiitwa chiremba anosarudza chete akapiwa murwere wacho.

Zvinodhaka kubva foxglove woolly

"Tselanid" - cardiac glycoside nokukurumidza chiito anogadzirwa chimiro mahwendefa uye mhinduro kuti intravenous jekiseni. Huru zvairatidza - kweropa kukundikana, tachycardia, atrial fibrillation.

"Digoxin" kunoratidzwa kuwedzera myocardial contractility, hakupesani ari coronary kuparadzirwa uye kunoderedza kuzvimba nokuda diuretic migumisiro. Nomutsinga uye nomuromo. It zvinoratidzwa nokuda kwazvo kweropa zvirwere uye panguva imwe kurwisa paroxysmal tachycardia panjodzi.

Kuchirapa zvazviri rinosvika vaifanira mushure nguva apo basa fuma mumuviri yakasvika imwe pfungwa. Pane tinofanira kugara kushanda (kuwanda) nokuti kuti Digitalis gadziriro kuonekwa zvishoma nezvishoma.