Drug "Armadin": mirayiridzo kushandiswa (majekiseni)

Kusvika panguva zvinodhaka "Armadin" iri kuramba kuwanikwa ano okurapa. Mirayiridzo dzokushandisa (majekiseni - isu vaiona chimiro) ari chokushandisa rakanyatsojeka kunzwisisa kuti kukura, maererano nako vakawanda vanosarudza kutsvaka yakawanda mashoko.

Next tikatarisa kuti chokushandisa, chii ayo zvakanakira nekuipira, uyewo sei kurishandisa nemazvo.

pharmacodynamics

"Armadin" ari specialized inhibitor chokuzvisarudzira-okunyanyisa urongwa, ndiko Kamudzira aidzivirira. Mukuita yokugamuchira zvinoreva riri nootropic, antihypoxic, stressoprotektornoe uye anxiolytic zvinokonzerwa, mumwe mushonga uyewo yekudyidzana anowedzera kuramba kufurirwa siyana kukuvadza zvinoita kislorodzavisimym uye pathological inoti.

By zvinodhaka "Armadin" mirayiridzo kushandiswa (majekiseni) inodaro chokwadi kuti kurishandisa kunonatsiridza ropa kuyerera chepfungwa uye chepfungwa muviri, akaderedza aggregation trombotsiotov, kuvandudza ropa rheology uye rayo microcirculation. Panguva iyoyowo vanachiremba kazhinji nopindirana achishingaira Pamazita pakuti nzira basa nokuda Kudzikamiswa rimwe Kamudzira zvivako ropa sero hemolysis apo, pane mabiko wayo sezvo kudzikira endogenous enzymatic kudhaka uye toxemia pana rikwanise pfungwa nomuviri zvemwana asati.

Ungazviita sei?

Enough rinotsanangura rinoreva "Armadin" mashandiro chiito kudzidziswa Chinyorwa (majekiseni), contraindications, uye dzimwe pfungwa. Operation izvi zvinoreva zviri kunokonzerwa membranoprotektornym uye antioxidant nemigumisiro. Mukuita kwekugamuchira yakawedzera basa superoxide dismutase hwakaipa lipid peroxidation ichiwedzerwa reshiyo "lipid-mapuroteni", uye zvinoderedza kuti viscosity ari Kamudzira, nokudaro vachiwedzera fluidity kwayo. Mukuwedzera, negashiro zvinodhaka anogona modulate nezvebasa makemikari akasiyana-siyana uye Kamudzira-akasungwa Kanotokonya yakaoma, ine kunobatsirawo nokugona kwavo kusunga kune ligands uye anochengeta STRUCTURAL uye dzichipfekeka sangano zvoutachiona membranes.

Special kutarisirwa inofanira kubhadharwa kuti chokwadi kuti kune mushonga "Armadin" mirayiridzo Chinyorwa (majekiseni) rinotsanangura chikuru zviri huchishanda uye Rinoratidzawo normalization pakati metabolic pezvakaitwa ari ischemic myocardium, ungaderedza necrosis, zvinoderedza uye haizopereri kuvandudzika pakati zvemagetsi basa uye contractility pamusoro myocardium, uye aivawo nouchapupu kuwedzera coronary ropa riyerere munzvimbo ischemic munharaunda. Kugamuchira izvi zvinoreva hunoita kuti kwenguva refu ndichengetedze retinal ganglion masero uye optic tsinga fibers pakuparwa mberi neuropathy, izvo zvingaita kuti chisingaperi hypoxia uye ischemia.

Zvimwewo Marwadzo kuvandudzika kunyanya kuona ari kushanda basa iri optic etsinga uye the retina, izvo anowedzera kutarisana acuity munhu.

Pharmacokinetics

By intramuscular kwokubatsira mushonga kunotemwa pachishandiswa ari plasma kwemaawa anopfuura mana. The zvachose nguva kusvika C _Max riri pakati anenge 0.45 kusvika 0.5 awa.

Zvinokosha kucherechedza ndechokuti mushonga ari kukurumidza kutanga kufamba kubva muropa kupinda munyama siyana uye nhengo, uye ipapo zvachose muviri. Izvi zvinoitika muna weti, kazhinji zvakanaka glyukuronkonyugirovannoy chimiro uye zviduku zvakawanda, uye ari kuchinja chimiro. Hazvina kunyanya vari vakaratidza gadziriro ino "Armadin" (majekiseni). The Zvinoumba chokushandisa ichi zvinosanganisira emoxypine kuti akakurumidza kunakidzwa nemudumbu.

Emoxypine mumuviri womunhu unotanga metabolize chaizvo kuzviita ane mberi rutapudzo kwaro glyukuronokonyugata. Kazhinji zvinobatsira pamusoro vanenge 12 maawa weti goho anenge 0.3% kuchinja zvinodhaka, apo 50% - rokuti glyukuronokonyugata.

The kunonyanyisa kuchinyanya eilmetilgidroksipiridina succinate pamwe glyukuronokonyugatom ake yabudiswa panguva maawa mana pashure kushandisa zvinodhaka ichi pakutanga. Kazhinji, senzira "Armadin" (kwepfuti) vanachiremba wongororo zvinosanganisira mashoko kuti excretion iri weti parameters ari chinhu uye ayo metabolites siyana yakawanda nomumwe variability.

Kana rakundwa?

Sezvo chikazozikamwa, kuti chokushandisa inowanika maviri siyana - mureza majekiseni uye mahwendefa. Yega rinoshandiswa nenzira dzakasiyana-siyana nguva saka unofanira kunzwisisa zvakanaka apo uye rudzii zvakanakisisa kusarudza. Kazhinji vanachiremba zvinobetsera ndishandise ari mudziyo, chimiro vakazvimiririra anoratidza mutambo wayo.

majekiseni

By zvinodhaka "Armadin" (kwepfuti) Mashoko aya kuti nenzira iyi kushandiswa kwayo unoratidzwa zvinotevera nyaya:

• kuvapo chakasimba kusagadzikana chepfungwa akaparadzirwa munyika;
• migumisiro siyana kukuvara dzechimwe pfungwa;
• cardiopsychoneurosis;
• encephalopathy;
• kuvapo chero kufunganya chirwere panguva percolation neurosis uye neurotic inoti;
• kuduku zvishande vanotaura Genesi pamusoro atherosclerosis;
• panowanikwa chikuru rakazaruka angled yemaziso pamusoro mumatanho siyana (kana iri mushonga "Armadin" (majekiseni) kurayirwa kutaura kuti kushandiswa kwayo anoratidzwa sechinhu Integrated vanzwe kurapa);
• Mufananidzo ucharwadziwa zvakadyiwa udhakwa, kana akatonga neurocirculatory uye neurosis-kufanana zvirwere.

mahwendefa

Ichi chimiro zvinodhaka riri zvairatidza siyanei kushandiswa:

• neurosis kana neurotic inoti nezviratidzo siyana mwoyo;
• migumisiro chenjera kusagadzikana chepfungwa akaparadzirwa munyika;
• cardiopsychoneurosis;
• encephalopathy siyana Genesis;
• Light zvishande nepfungwa dzakasiyana Genesis;
• havachanyatsogoni ndangariro, kana pamberi kwepfungwa kushayiwa mune vanhu pakukwegura;
• kuduku Kukuvara mumusoro uye migumisiro yazvo;
• absinentny alcohol syndrome pamberi autonomic neurosis kana vascular zvirwere;
• siyana asthenic ezvinhu kana kuona yokunyanyisa zvinhu;
• kudhaka ezvinhu dzakwidzwa dzakabudirira siyana antipsihotropnymi nzira;
• coronary tsinga chirwere;
• Cardiology yakasanganiswa kurapa;
• dislipoproteinemia atherogenic mhando.

Sei majekiseni?

Saka chiremba wacho waitaura zvinodhaka "Armadin". Majekiseni intramuscularly kana nomutsinga raitongwa anogona kuchadonha kana ndege. Dose neimwe nyaya vanosarudzwa chete kushandisa munhu kusvika, kuti vanofanira vatora navanachiremba vakakodzera.

Kana kushandisa nzira iyi chourongwa of aizomupa gadziriro vanofanira kuramba vari vasiri yavaibvisa chloride mhinduro. Zvinokurudzirwa kutanga kurapwa vakuru vane mishonga kubva 50 kusvika 100 MG, iyo chinotarisirwa munhu katatu pazuva. Naizvozvo Mavhoriyamu inogona hwakawedzera, izvo zvairatidza kuti mushonga "Armadin" (majekiseni) kudzidziswa. The ampoules ane mushonga pacharo, izvo zvinofanira kupiwa zvishoma nezvishoma pamusoro 5-7 maminitsi ndege, ukuwo inodonha "Armadin" hunosumwa panenge kumhanya 40-60 anosiya miniti ose. Maximum zvichibvira zuva nezuva dose kuti medicament ndiyo 800 MG.

Kana paine kutyorwa mu chakasimba chepfungwa kweropa hurongwa zvinodhaka anopiwa mumazuva 2-4 nomutsinga kune vakuru 200-300 MG ose maawa 24 sezvo chikamu kunzwisisa kurapa, pashure pacho rinoshandiswa muchimiro intramuscular majekiseni ari dose 100 MG ose katatu pazuva. Panyaya iyi, ya kunokwanisa kusvika mazuva gumi nemana.

Kana cranial kukuvara kana zvavo siyana zvinokonzerwa, mushonga unoshandiswa kwemazuva 10-15 ne intravenous jekiseni iri vhoriyamu nguva 200 kusvika 500 MG 2-4 rimwe zuva.

Kugadzirira "Armadin" (majekiseni) raitongwa pamwe vascular encephalopathy decompensated apo rinoshandiswa nomutsinga nokuda donhwe jekiseni mune mishonga 100 MG maviri kana katatu pazuva kwemazuva 14, pashure pacho rinoshandiswa intramuscularly kwevhiki mbiri pa 100 MG kaviri pazuva. Mukuwedzera, mushonga rinoshandiswa kwacho uye kudzivirira vascular encephalopathy kosi nedzevakuru kubudikidza intramuscular kwokubatsira 100 MG kaviri pazuva kwenguva kubva 10 kusvika 14 days.

Myocardial infarction

Kana murwere yaitirwa chakasimba myocardial infarction, ipapo zvinodhaka ndiko "Armadin" (majekiseni) intramuscularly kana nomutsinga raitongwa kwemazuva 14 pamwe mureza kurapa kusanganisira siyana thrombolytics, ACE FIs, Symptomatic, antiplatelet uye anticoagulant nevasori, uyewo nitrates. Mumazuva mashanu kushandiswa kwayo kuti vabudirire kufadza zvinoita mugumisiro wokutanga, Zvinokurudzirwa kushandisa mudziyo nomutsinga. Muvhiki mapfumbamwe mazuva kare anotipa intramuscular yaitonga.

Intravenous Kutarisirwa ari kuitwa donhwe aizomupa, uye mushonga uyu anofanira kupiwa zvishoma nezvishoma kuitira kubvisa ngozi nemishonga. The medicament inoshandiswa 0,9% yavaibvisa chloride mhinduro kana 5% dextrose mhinduro iri vhoriyamu anenge 100-150 Rine mamiririta. Musumo rinoitwa kwemaminitsi 30-90. Kana zvakakodzera, mushonga "Armadin" (majekiseni) kutarisirwa kunonoka bolus kwemaminitsi 5.

Agent anofanira kuzviita katatu pazuva ose 8 maawa. The daily kuchirapa dose, muchiitiko ichi anoda kubva 6 kusvika 9 MG chete kilogram nokushivirira muviri uremu, uye chete dose ose, ukuwo, 2.3 MG / makirogiramu muviri uremu. Maximum zvichibvira zuva nezuva dose iri 800 MG, ukuwo mumwe-nguva yakarumbidza chinofanira kutarisirwa hapana MG zvinopfuura 250.

nezvimwe zvirwere

In pamberi alcohol syndrome absinentnogo zvinodhaka chinotarisirwa ari dose pamusoro 100-200 MG intramuscularly maviri kana katatu pazuva, kana anogona kushandiswa intravenous aizomupa 1-2 nguva pazuva kwemazuva 5-7, sezvinoratidzwa pachishandiswa "Armadin" User chikumbiro (majekiseni). Reviews vanachiremba uyewo anoratidza kuti pamberi rikwanise kudhaka antipsychotics zvinodhaka anofanira kuzviita chete nomutsinga panguva mishonga kubvira 50 MG kusvika 300 MG zuva nezuva kwemazuva 7-14.

Kana paine anogumbura chero pezvakaitwa ari abdominal mhango nzira iri tanzi rokutanga zuva rive preoperative, uye ipapo - sezvo postoperative kurapa. Panyaya iyi, kuti chipimo chemushonga achaenderana kwokuomerwa uye nezvimiro kuzomukazve chirwere, chiremba kosi uye muitiro kupararira zvakananga. Zvinofanira kucherechedzwa kuti kana zvakakodzera, bvisa zvinodhaka ichi chinofanira kuitwa zvishoma, uye chete pashure pacho kunokwanisika kwakaenzanirana zvakanaka kurapwa uye mumarabhoritari nemigumisiro.

Apo chenjera edematous pfungwa nomuviri zvemwana asati medicament rinoshandiswa mishonga 100 MG katatu pazuva nomutsinga kana intramuscularly zvichienderana nachiremba wacho kuverenga.

Zvokungwarira

Special kutarisirwa chipiwe kugadzwa mushonga varwere vane sema kare. Mune zvimwe zviitiko, vanhu vane asima pamberi kunyanya aikanganiswa sulphate inogona kuchengetwa kukura zvikuru hypersensitivity siyana. Pashure vapedza achaita parenteral kutarisira kuti tirambe kuti kubudirira zvazvinoita anokurudzirwa kuramba kushandiswa chishandiso mukati dziri mahwendefa.

Pane zvidzidzo hapana zvakanaka raitungamirirwa zvekuchipatara pamusoro kuchengeteka chivako ichi panguva womuchato panguva lactation kana pamuviri haina kuitwa, saka kuti vanachiremba regai kuvakurudzira kurishandisa iyi. Saizvozvowo, ongororo dzakati kuti dzakaitwa pamusoro kuchengeteka zvinodhaka zviri kushandiswa kwayo nokuda kurapwa vana maererano chii kwavari chiri haana varumbidzwa kushandiswa kwayo, kunyange chiitiko abovementioned zvirwere.

Uyezve, zvinokosha kuziva kuti mukufamba kurapwa zvakakodzera kuti kungwarira zvikuru apo kutyaira motokari kana zvigadziriswe siyana, sezvinoratidzwa pachishandiswa "Armadin" mirayiridzo kushandiswa (majekiseni). Analogs zvinodhaka kazhinji zvakasiyana zvakafanana nemishonga. Izvi Somuenzaniso, akadai "Meksidol", "Mexicor", "Meksifin", "Neurox".

Pakati kushandiswa kwenguva yakareba pamusoro zvinorondedzerwa medicament anogona kuratidza imwe nhamba nemishonga, kusanganisira kuneta, bloating kana peripheral edema. Kana achiita nomutsinga (kunyanya chokuita ingi ndege) kuonekwe imwe esimbi kuravira mumuromo, huro nokushatiriswa manzwiro nokupisa munyika muviri, palpitations, tachycardia, Flushing chiso uye zvimwe zvinokonzerwa, iyo chokuita kukwirira nokumhanya pakatanga "Armadin" gadziriro ( majekiseni). Reviews zvinoratidza kuti migumisiro idzi pfupi.