Drug "paracetamol" - sezvamunoita, zviratidzo, contraindications

Kugadzirira "paracetamol» ane sezvamunoita anosarudza mano mushonga kuderedza tembiricha uye kuderedza marwadzo ndiyo inonyanya kufarirwa unonyaradza marwadzo uye antipyretic kungova anilide boka. Form zvinodhaka kusunungurwa ndiyo siyana chaizvo. manyuchi ichi uye suppositories, elixirs uye madonhwe, mahwendefa (pachena, chewable uye effervescent), uyewo negadziriso jekiseni uye kuti munyika yaitonga.

Kugadzirira "paracetamol" vane nzira unotora makemikari mukomboni N- (4-Hydroxyphenyl) acetamide, iri metabolite kuti phenacetin uye ane nzvimbo yakafanana nayo. The chikuru zvakanakira munhu medicament zvingasanganisira pasi toxicity kwayo uye kukwanisa kuumba methemoglobin duku. Chirwere kwokubatsira dzakakwirira mishonga, mushonga anogona kukonzera zvinenge nenjodzi, asi mushonga "paracetamol", rinoumbwa vakachengeteka rwuripowo WHO mazita inonyatsobudirira analgesics varumbidzwa dzokushandisa vana. In mazwi mumuviri zvatariswa, ndiko crystalline upfu ane chena kana ruomba chitsvuku chine roruvara rwakatsvukuruka tinge. Paracetamol iri nyore zvazvichanyungudutswa doro.

Munguva pharmacological zvainoita muviri zvinodhaka kutigumbura ari enzayemu cyclooxygenase simba prostaglandins. Drug "paracetamol" vane sezvamunoita anogona kupesvedzera musimboti marwadzo uye mutemo kupisa kunokanganisa musimboti tsinga. The mushonga wefodya ne zvomudumbu wemuTesitamende pfupi uye anosunga kuti mapuroteni eplasma mu uwandu gumi muzana. Chemical kuchinja yezviri fuma anogadzirwa chiropa. Izvi unoumba paracetamol glucuronide uye sulfate. Yabudiswa zvinhu zvinodhaka yabudiswa kuburikidza neitsvo. Kana kugamuchira mushonga lactating vakadzi chityu mukaka asingasviki chimwe muzana dose zvinodhaka.

Kugadzwa zvinodhaka "paracetamol" vane sezvamunoita runoita kubvisa ari chipatapata uye marwadzo, nokuti kurapwa zvirwere, ari kutapuriranwa yezvakaita kubereka. Vanogona kuva arthralgia uye neuralgia, myalgia, uye migraine algodismenorei uye ndichinzwa zino uye nomusoro. The mushonga hakuna zvainoita kuchiita chirwere uye akaronga kuti symptomatic kushanda uye vambotibatsirwei murwere wacho nemamiriro.

Marwadzo "paracetamol" chinodhaka tsanangudzo anogona kuwanikwa mumirayiridzo kwaigona kuguma kutyora paumbwe nhengo dzakavandika ari mudumbu kana kugamuchira mushonga nemukadzi pamuviri. Somugumisiro kushandisa zvinodhaka zvingava aseptic pyuria, renal colic, kupererwa neropa, anemiyainterstitsialny glomeruonefrit uye neutachiona paganda.

Drug "paracetamol" harigadzwi pasi zvinotevera ezvinhu:

- Munhu aikanganiswa ayo akafanana,

- erosions uye urikanwi pezvakaitwa ari zvomudumbu ino;

- pamwe Árbol asima polyposis mhino uye paranasal sinuses ose kuitazve mu pachikuva;

- kusada acetylsalicylic asidhi;

- mberi itsvo zvirwere unhu;

- anogumbura zvirwere nemudumbu;

- Active chiropa chirwere;

- ropa ari nemudumbu;

- vapore pashure coronary tsinga ndavhiyiwa;

- hyperkalemia.

Akaramba kutora mushonga ari chekupedzisira chemwedzi mitatu yenhumbu, sezvo Haapi mucheche mwedzi upenyu.

With Kunyatsongwarira kushandiswa chigadzirwa pasi zvinotevera zvirwere:

- nemavhairasi chiropa;

- kudhakwa;

- itsvo, chitaka uye mwoyo kutadza;

- cheshuga;

- somatic zvirwere kwazvo;

- peripheral arterial chirwere;

- nechikakananda kujairira;

- cardiac ischemia.