"Formetin": mirayiridzo kushandiswa, zvechokwadi

Pari takawana vanhu vakawanda vane chirwere cheshuga uye matambudziko anoitika kufutisa mhando. mishonga yakawanda dziripo kurapa zvirwere izvi. Mumwe wavo ari mushonga "Formetin". Its salient zvinhu zvichange kutsanangurwa munyaya ino.

mishonga chikamu

"Formetin" mirayiridzo kushandiswa icho kuratidzwa munyaya ino, ndiye biguanide boka zvinodhaka ane hypoglycemic.

Description of nziyo uye kusunungurwa fomu

Mune rimwe piritsi kwayo;

Available mushonga "Formetin" iri Maronda akasiyana 100, 60 kana mahwendefa 30.
Color White mahwendefa uye chipimo chemushonga chimiro kunobva nechigadziko zvinhu. At 500 MG ploskotsilindricheskoy vane raundi chimiro pamwe chiratidzo uye chamfered. Uyewo chipimo chemushonga pamusoro 1000 MG kana 850 MG ane "Formetin". Mahwendefa kana ichi, convex uye denderedzwa. Ndivo chete-mativi ngozi.

pharmacodynamics

Metformin ( "Formetin") DZEMUNHU DZINODZORA gluconeogenesis unoyerera ari chiropa, uye nokudaro pane kuderera glycogen muzvitoro nayo. chokushandisa Izvi zvinobatsira kuti kuoma Absorção de Água kubva intestinal shuga, chiwedzere kubviswa ropa shuga kwevari hurongwa. Izvi zvinowedzera kwaiita munyama kuti jekiseni pasina kukanganisa kugadzirwa kwayo kwemakemikari anobudiswa chikamu rwatata B-masero, pavaigona kutora chikepe chaienda hypoglycemic maitiro, sezvo isina kusashanda kugadzirwa akati fuma.

Drug "Formetin" wongororo iyo kutaura kushanda kwayo, zvinoderedza uwandu ropa iri remafuta akawandisa "zvakaipa" uye triglycerides. Zviri kumusoro arambe achirema lipoproteins ichi chinowedzera 20-30%. Tiine ineffectiveness zvataidya zvinodhaka "Formetin" mirayiridzo kushandiswa inorondedzerwa munyaya ino zvinobatsira kuderedza uye / kana dzikamisa uremu murwere. Izvi zvinoitika nokuda oxidation kuti shuga nokuda okisijeni-vakasununguka uye kuderedza havi. Uyewo zvakanga zvokomara zvinyama plasminogen activation muitiro uchiita ayo inhibitor, sezvamakaropafadzwa hemostatic kwepasi rinooneka.

Pharmacokinetics

Kuitwa metformin kunotanga nemudumbu. The kunonyanyisa kwazvo fuma muropa riri maawa anenge 2,5 pashure chikumbiro pa mwero Absorção de Água chikwata dose - 50-60%. Kubvisa unhu zvinodhaka mumuviri kunokanganisa kubatana pakati yezviri fuma uye puroteni iri plasma. Pamahwandefa "Formetina" hapana kubatana kuti mapuroteni eplasma. It anotaura pamusoro kugona kwaro. Sezvo duku nokusungwa chinhu, mushonga wefodya nani. Deposition ndiye itsvo, chitaka, mune tsandanyama rinenge riri mate mumasero. Mumuviri, metformin anoramba kuzochinja. Zvadaro yabudiswa pedyo neitsvo. Naizvozvo, kana kuti zvaipesana basa ravo riri kuchengetwa kuwanda. Biological hafu-upenyu maawa 1.5-4.5.

ramangwana

Medicine "Formetin" rinoshandiswa kuti kurapwa vamwe Mapato zvirwere. Kureva, pamberi mhando II cheshuga, pamwe kufutisa nyaya pamwe kuoma kana zvokudya asingadi kubatsira kuchengeta ropa shuga yomuropa kuipa, kunyange Rakabatanidzwa pamwe sulfonylurea. Uyewo inobudirira ndiye "Formetin" uremu.

Sei kutora?

The dose of chiremba zvinoreva asarudza, kwakavakirwa uwandu kuti shuga muropa. Oral Kutarisirwa zvinokosha kushandisa pashure kudya, kunwa pamwe yakawanda emura uye achifumura piritsi machine. Sezvambotaurwa pamusoro apa, chipimo chemushonga iri ushandiswe zvichienderana zviri shuga muropa. Kuchitanga risingamboshandisi mari - 0.5 d kana 0,85 g pa zuva. Mazuva maviri pashure kutanga kurapwa pamwe zvinodhaka ichi chave vachiwana zviri metformin muropa. Optionally, zvishoma nezvishoma kuwedzera dose kusvikira vaifanira ukoshi. Zviri yakaenzana 3 magiramu.

Sezvo vakwegura kazhinji vakachengeta kukura lactic acidosis, kwavari huwandu kufadza zuva dose pakati 1 g chitsama zvinodhaka iri kwakaderedza zvaipesana muviri, kuti kudzivirira sema maitiro, izvo kunooneka pacharo muchimiro ganda rashes, uye zvimwe yaivhuvhuta zviitiko zvichibvira, izvo zvichashandiswa wainyatsotaura pazasi.

Contraindications

Panyaya iyi, pane nuances zhinji. Drug "Formetin" mirayiridzo kushandiswa icho kuratidzwa murugwaro urwu, ari contraindicated pamberi:

• Chirwere cheshuga ketoacidosis, precoma, pakoma.
• Zvakakomba vasingadzoreki renal functionality.
• Cardiac uye kufema kukundikana.
• Chenjera chokutambudzika myocardial infarction.
• Kupera mvura mumuviri.
• Chirwere udhakwa uye zvimwe zvirwere zvinogona kukonzera kuratidzwa nekukudziridza lactic acidosis.
• Chenjera sitiroko.
• Pamuviri uye achiyamwa.
• Hypersensitivity kuti srudstvu ichi.
• Kuvhiya Major kana kukuvara, kana jekiseni anogadzwa.
• Zvakakomba zvinotapukira.
• Functional kusagadzikana chiropa.
• Chenjera doro chepfu.
• Lactic acidosis (kusanganisira nhoroondo).
• Hypocaloric kudya (asingasviki 1000 kcal. Per zuva).
• Adioizotopnyh kana radiographic zvidzidzo, kwokubatsira nefuma iodide mhando.

Zvinonzi zvakare haana yakarumbidza kushandisa zvinodhaka "Formetin" vanhu kwemakore matanhatu, kuita muviri yakawandirwa basa. Sezvo iyi, vane mikana yokuita lactic acidosis.

divi kushanda

The panowanikwa zvakadai zvisingafadzi zviratidzo se "esimbi" kuravidza mumuromo, kurutsa, kuda kurutsa, manyoka, flatulence, kushaya havi zvinoda discontinuation wokushandiswa kurapwa uye pakarepo zvivabatsire kune nyanzvi. kushandisa zvinodhaka refu kunokonzera nyonganyonga kana kumira yaunodya vhitamini B _12, iyo inosvitsa kuunganidza mumuviri neyokupedzisira, zvichiita vhitamini pokuperevedza zvakakwana. Mune zvisingawanzoitiki Muzviitiko, dzichiri neizvi - megaloblastic The _12-shoma kupererwa neropa. Kana isina kukodzera raitongwa dose zvichibvira yomuropa. Ungazvidyawo kuona neutachiona akadai ganda nekumhanyirira. Saka, mushonga "Formetin" wongororo iyo iri Kukodzera yayo kushandisa akasiyana, zvinofanira vanogadzwa chete kupinda chiremba.

Zvokungwarira

Chimwe chinhu chinokosha rinotsanangurwa nzira nekuchengeta zvekudya fuma "Formetina" mumuviri uye migumisiro ichi.

Kuti adzivise kuunganidza lactic acidosis uye kudzivirira metformin, zvakafanira kuongorora zviratidzo zviri itsvo nerevane kuti miedzo kuona zviri lactic asidhi mumuviri kanenge 2 nguva pagore. Uyewo, kana uine marwadzo ari tsandanyama anofanira retested.

The mugumisiro vakati zvinodhaka riri kukwanisa kudzinga zvigadziriswe uye kutyaira motokari

Muchiitiko chino, sezvo vamwe nuances. Impact "Formetina 'Kukwanisa michina uye yokufambisa kuchiitika chete kana kushandiswa pachiimbwa zvinodhaka kukanganisa kushanda kwemasayendisiti kuti zvinoda kumhanya mhinduro uye yakawedzera yevasungwa. Zvakakosha kuziva.

Kushandiswa pamuviri uye achiyamwa

Kugadzirira "Formetin", mirayiridzo kushandiswa inorondedzerwa ino, ane migumisiro pamusoro azvarwa muchikwata «B» kubudikidza FDA. Panguva pamuviri anogona kugamuchira mari iyi. Zvisinei, kushandiswa kwayo kunogona chete mune zvimwe zviitiko. Zvinoti - kana kutarisirwa zvawanikwa kubva kurapa ino kusapfuudza Kuwanikwa zvingakanganisa azvarwa. Nyatsotaura nyaya zveBhaibheri kushandisa chombo akadai mushonga "Formetin" chaiitirwa panguva yepamuviri. Panguva kurapwa ngaanyarare achiyamwa. Chero zvazvingava, unofanira kubvunza chiremba anokwanisa.

zvinodhaka kwavatori

Metformin kunowedzera padanho yomuropa. Izvi zvinonyanya kuoneka pamwe mawa negashiro asiri steroidal Anti-anogumbura zvinodhaka, sulfonylurea nomukaka uye clofibrate, monoamine oxidase FIs, acarbose, jekiseni, oxytetracycline, cyclophosphamide, FIs ane angiotensin rokutendeutsa enzayemu blockers uye mhando.

Kana rikashandiswa pamwe kwemakemikari anobudiswa zvinodhaka (nemumuromo nhumbu, corticosteroids, sympathomimetics epinephrine, thyroid shwanu mahormone, glucagon, thiazide uye "loop" diuretics, phenothiazine nomukaka, nicotinic asidhi nomukaka) anogona metformin hypoglycemic braking rikurumidze.

With ibatanidzo chombo akadai mushonga "Formetin" ne "Tsimidinom" "nifedipine" kuwedzera mukana lactic acidosis, metformin zvichivhiringidza ari excretion kubva mumuviri. Kwakadaro akaona basa iri chidhakwa zvigadzirwa, zviri Vol. H. In murwiyo mishonga.

Cationic vamiririri (quinidine, amiloride, digoxin, procainamide, morphine, Quinine, vancomycin, ranitidine, triamterene) yakaumbwa muna tubules, kukwikwidzirana nokuti nezvifambiso zvinosvika uye kurapwa kwenguva refu anogona kuwedzera pamwero zvinodhaka wevasungwa 60%.

ovhadhozi

Ovhadhozi "Formetinom" akacherechedza apo achitora 0,85 magiramu pazuva uye vakandizvidza lactic acidosis. Uyewo, refu zviri metformin nokuda itsvo kutadza.

zviratidzo lactic acidosis Early ndivo neutera muviri wose, bloating, pasi muviri tembiricha, kurwadziwa nomudumbu uye tsandanyama, yakaderera BP, dzepanguva bradyarrhythmia. Mune zvimwe zviitiko, pane kakawanda kuratidzwa kufema zvirwere, dzungu, uye, sezvo zvakaguma pane kukura pakoma.

Kuchangotanga pakati zviratidzo ovhadhozi vanofanira kurega kushandisa zvinodhaka uye chiremba kuzosimbisa chirwere pamusoro lactic acidosis. Nokuti nokubviswa vanoshingaira pafuma pomutumwa uye lactic asidhi kubva muviri kuchaita hemodialysis kufanana symptomatic kurapwa.

"Formetin": dzomuzana

Pane zvakawanda pfuma iyi mhando. Analogues "Formetina" protrude Formulations ane ayo anoumba sechinhu chikuru chezvinonhuwira metformin hydrochloride. Mumwe muenzaniso uri mushonga kuti vaburitsi Russian, "Vero Metformin," "Gliformin", "metformin", "Metformin-Richter", uye mhiri kwemakungwa - "Glucophage", "Glucophage" uye "Glyukofazh Long" (France), "Lanzherin "(Slovakia)" Metfogamma "pamwe kunosiyana dosages pamusoro vanoshingaira zvacho 0,100, 0,500 uye 0,850 d (Germany).

Conditions uye mazwi

Panyaya iyi, pane zvimwe zvinhu. Kugadzirira "Formetin" riri simba, saka anosunungurwa bedzi mushonga uye kunoda okuchengetera pa nzvimbo tembiricha, pasigasvikirwi vana uye chiedza chezuva nzvimbo. Pasherufu upenyu nayo - 2 years.

mari

Avhareji yemari nokuda zvinodhaka "Formetin" zvinoiswa zvichienderana chipimo chemushonga kubva 59 rubles. 0.5 g ari mhoni, 133 rubles. pamusoro 0,85 d uye 232 rubles. pamusoro 1 gore

mhedziso

All zvataurwa chinosanganisira yakawanda anobatsira mashoko. Pashure kuverenga nyaya ino, vose achakwanisa kuwana mhinduro yomubvunzo wokuti sei kutora 'Formetin "uye chii ine zvivako.