"Moxonidine": mirayiridzo kushandiswa, zvechokwadi

Chii mushonga "Moxonidine"? Mirayiridzo kushandisa nzira iyi, akaongororazve nezvazvo, contraindications, uye analogs vanotsanangurwa zvakadzama munyaya ino. Uyezve, isu vachakuudza pamusoro zvatiri kufunga rinotarisirwa zvinoreva, kana ane chero divi migumisiro uye chimiro umo iri rakapa.

The chimiro uye Kuronga zvinodhaka

zvinogoneka kutenga zvinodhaka "Moxonidine" In ipi? mushonga iyi chete inotengeswa muchimiro mahwendefa. Dzavo kushingaira chaikosha iri fuma yakadai moxonidine. Panyaya okuwedzera zvinoriumba chokuita kwazviri cellulose microcrystalline, mafuta Castor, Aerosil A-380, hydroxypropylcellulose, magnesium stearate uye Tween-80.

Mahwendefa vanotengeswa mune makadhibhokisi pasuru. Mumwe pasuru kungava 98, 60, 56, 42, 40, 30, 28, 20, 14 uye mahwendefa 10.

The pharmacological ehupfumi zvinodhaka

Sei Ndinoda mishonga "Moxonidine" sei? Mirayiridzo dzokushandisa inotaura kuti gadziriro iyi ndiyo antihypertensive zvinodhaka. mashandiro ayo kuita iri ndechokuti basa fuma nzira kunokanganisa musimboti Links BP murau. Nemamwe mashoko, moxonidine - imidazoline Kanotokonya agonist iri (zvikurukuru).

The mushonga kuchititadzisa zvinoitwa pakati vasomotor centre, kuderedza achiburukira tsitsi chaizvo kumwoyo. The kumanikidzwa (diastolic uye systolic) kunoderedza zvishoma nezvishoma.

medicament runoonekwa nesu rakasiyana nemamwe antihypertensive sympatholytic yomuchipatara pakuti ane chete chiduku sungano kuna Arifa-2-adrenoretseptoramm. Izvi anotsanangura yakaderera ndingangokuvara muromo yakaoma uye nyaradzo.

Hatigoni kutaura kuti moxonidine anogona kuwedzera jekiseni wanda indekisi (vanenge 21 muzana) muna vanhu vane kufutisa.

Pharmacokinetics zvinodhaka

Apo mushonga wefodya, "Moxonidine"? User chikumbiro inoti kuti pashure kugamuchira medicament pakarepo uye akapotsa zvachose muzvinhu rokumusoro zvomudumbu turakiti.

Bioavailability (Mhedziso) ari chokushandisa 88 muzana. The kunonyanyisa pfungwa kunoitwa pashure makumi matanhatu nemashanu maminitsi. Panyaya iyi, kudyiwa zvokudya maturo pamusoro pharmacokinetics yezviri chinhu haana.

Kukurukurirana neropa mapuroteni anenge 7,3%. Chikuru metabolite pamusoro Moxonidine Moxonidine anoita tasara tisina mvura, uye guanidine nomukaka.

The hafu-upenyu moxonidine uye ayo metabolites raiva 150 uye 300 maminitsi azvaitwa.

Mushure ingestion kwemaawa makumi maviri nemana zvinodhaka yabudiswa parutivi itsvo ari Vhoriyamu 90%. Uyewo, zvinoshingaira fuma chinobuda uye kubudikidza ura.

Zvairatidza kuti kushandisa zano wezvokurapa

Mune zvimwe zviitiko, prescribers 'Moxonidine "? Kushandiswa kwezvinodhaka ichi kuratidzwa chete kana zvokurwara akadai neBP arterial.

Contraindications kuti kushandisa zano wezvokurapa

Mune zvimwe zviitiko, vanachiremba havana mishonga kuti varwere vavo 'Moxonidine "? Mirayiridzo yokushandisa zvinodhaka ichi chine haisi refu chaizvo mazita contraindications. Funga zvino.

Saka contraindications pakushandisa "Moxonidine" gadziriro vari zvinhu zvinotevera:

• akaratidza AV-chezvakaipa 2 uye 3 madhigirii, SSS;
• bradycardia (anorova asingasviki 50 paminiti);
• kuyaruka uye vana zera (Makore 18);
• chisingaperi uye rikwanise mwoyo kutadza;
• mwana zvokudya kumwedzi;
• Hypersensitivity kuti zvinoshingaira maatomu akafanana.

The mushonga "Moxonidine": mirayiridzo kushandiswa

Testimonials pamusoro medicament ichi zvichakurukurwa panopera nyaya. Zvino ndinoda kukuudza sei kushandisa mushonga zvakanaka pamberi pedu.

Drug "Moxonidine" vari chete mukati. Chipimo chemushonga mukutanga zvinodhaka kurapa kunofanira 200 micrograms kamwe pazuva. Nokufamba kwenguva, unogona kutora 400 micrograms.

Zvinoda Munhu Kugadziridzwa rugwaro uwandu kurapwa zvichienderana tolerability zvinodhaka mishonga. Maererano mirayiridzo, kufadza chipimo chemushonga pamusoro medicament pazuva iri 600 MG (rakakamurwa matanho maviri).

Nokuti varwere renal insufficiency (mwero uye kwazvo), uye vanhu vari hemodialysis, mushonga chinotarisirwa mune imwe mari 200 MG kamwe pazuva. Kana zvakakodzera (nokutsungirira zvakanaka), iyo yakanatsa chipimo chemushonga anogona ngazviwedzerwe kufadza (i.e. 400 MG).

Nemigumisiro pashure pakugamuchira medicament

Ko divi zvinokonzerwa zvinodhaka "Moxonidine"? Testimonials nezvake kuti dzimwe nguva mishonga kunotoita kuti munhu Kuipa utano. Funga Nyora divi anokonzerwa rine mirayiridzo:

• Tsinga (nechepakati): nomusoro, kufenda, dzungu, uye somnolence.
• Zvomudumbu turakiti: kurutsa, yakaoma muromo, manyoka, dyspepsia uye svoto.
• kumwoyo: bradycardia, kwakaratidzwa donhwe BP, orthostatic hypotension.
• Skin uye subcutaneous zvinyama zvirwere: angioneurotic edema, pruritus uye ganda nekumhanyirira.
• Vairwara nepfungwa: kutya uye kushaya hope.
• Labyrinth zvinetso zviri auditory nhengo: achirira munzeve (zvinoitika chaizvo kashoma).
• System zvetsandanyama nemapfupa: marwadzo shure, kurwadziwa pamutsipa.
• Common nemishonga: peripheral edema uye asthenia.

Sezvaunogona kuona, "Moxonidine" mapiritsi anogona kukonzera kuparara murwere ezvinhu. Kana marwadzo vari kutaurwa, ipapo dose kurapwa kunofanira vakarega.

zvinoreva kuti kudyidzana nevamwe zvinodhaka

To zvinodhaka "Moxonidine", "Moxonidine Sandoz" uye dzimwe analogues zvinodhaka akabatsira murwere uye haana kukonzera kuti mimwe kumukuvadza, vanofanira kutorwa chete mushonga. Mushure mawa negashiro chishandiso nevamwe mishonga anogona kukonzera vasingadiwi siyana. Chii chaizvo, tichakurukura ikozvino.

Imwe-nguva kushandiswa zvinodhaka "moxonidine" pamwe chete antihypertensive yomuchipatara zvinogona kukonzera munhu chirungiso kushanda.

Antidepressants (tricyclics) kuderedza kunyatsoshanda mishonga antihypertensive nechepakati chiito. Panyaya iyi, havana varumbidzwa kushandiswa pachiimbwa yakadaro fuma sezvo moxonidine.

Viewed Zivisa medicament kunogona kuwedzera nyore migumisiro zvinodhaka, tricyclic antidepressants, uyewo panyaya iyi, hypnotics uye sedatives.

The kushingaira fuma iri medicament mwero attenuated anovandudza zvishande mabasa vanhu panguva imwe chete vanogamuchira lorazepam.

Nepo kugadzwa "Moxonidine" zvinodhaka uye "benzodiazepine" anogona kusimbisa nyaradzo nomukaka wevakabhuroka.

Nyanzvi dzinoti Moxonidine inotengwa nevanhu tubular secretion. Maererano neizvi hazvifaniri kushandiswa zvinodhaka kuti vanoitwa kusiyaniswa tubular secretion.

Nguva gestation uye lactation (pamuviri uye lactation)

Vanogona nguva gestation kutora mushonga "Moxonidine-LF"? Instructions chinodhaka rine mashoko ari zvachose aidzora uye zvidzidzo zvakakwana pamusoro kuchengeteka mishonga vaiona panguva yepamuviri chaiitirwa. Ndokusaka haisi varumbidzwa kushandisa chikamu ichi varwere.

Hatigoni kutaura kuti zvinodhaka "Moxonidine" harifaniri kushandiswa paanenge achiyamwa. Izvi imhaka yokuti kunoratidzwa naamai vake mukaka. Kana panguva lactation zvinodhaka asi agadzwa, ipapo uchiyamwisa anofanira vakarega.

Mukuita yezvidzidzo (experimental) kwemhuka, kwakaonekwa kuti medicament zvakunoita embryotoxic.

nhungamiro chaiwo pamusoro pokushandiswa mishonga

Maererano zvakabatanidzwa instructions, apo kushandiswa zvinodhaka "Moxonidine" anofanira kunyanya kungwarira. Kunyanya nezvezvitadzo imwevo chikamu wevarwere. Izvo, isu tsanangura ikozvino.

Kunyanya nokungwaririra kana kushandisa "Moxonidine" medicament kuti kuonekwa varwere AV-blockade 1st dhigirii. Izvi imhaka yokuti kwakadaro vanhu pane mukana mukuru bradycardia.

Uyewo kugamuchira mushonga inofanira kuitwa pasi pokudzora chiremba zvakaoma. coronary tsinga chirwere, itsvo kukundikana uye kusagadzikana angina. Izvi imhaka yokuti chiitiko kushandisa zvinodhaka pamwe abnormalities kwakadaro hakusi zvakakwana.

Kana uchida kubvisa mawa kushandisa zvinodhaka "moxonidine" uye Beta-blockers, unofanira kutanga kubvisa chokupedzisira, mazuva mashomanana gare gare - wechipiri.

To musi hapana uchapupu kuti kumisa "Moxonidine" mushonga kunotungamirira vawedzere BP. Zvisinei, pasinei kuti nyanzvi asi dzinokurudzira kuti danho kunze mishonga. The chipimo chemushonga inofanira kuderedzwa mumakore mavhiki maviri.

kana mushonga kunokanganisa kugona kudzinga motokari senga?

Munguva yokurapwa ne "Moxonidine" vanhu kungwarira kunyanya kana kuita mabasa ngozi, uyewo achityaira imotokari. Izvi imhaka yokuti chinodhaka anogona kuvhiringidza kugamuchirwa wevasungwa uye psychomotor zvavaifunga.

Analogs, uye mari zvinodhaka

Kutenga mushonga "Moxonidine" iri chemishonga zvaunogona pasina mushonga. Mari zvinodhaka ichi achiri pasi. Per rongedza, rine mahwendefa 14 Uchazoti kubhadhara anenge 115-135 rubles Russian.

Kana tiri kufunga mushonga urege kuuya, kana iwe chete vasina kuzvinzwisisa panguva chemishonga, pashure zvivabatsire kune nyanzvi, yokupedzisira vanosungirwa varumbidze zvinodhaka analogue. Pakati mishonga izvi ndinoda kuratidza zvinotevera: "Fiziotenz", "Moxonidine-C3", "Moksarel", "Chinyorwa Moxonidine", "Moksoniteks", "Moksogamma", "Tenzotran" uye zvichingodaro.

Tora mari inofanira kuva zvakasimba maererano yachiremba kurumbidzwaka. Uyewo, asati kushandiswa mishonga anofanira kuziva zvakabatanidzwa nemirayiridzo.

The mushonga "Moxonidine": wongororo vanachiremba uye varwere

Maererano nezvokurara, mushonga uyu unoshanda chaizvo kuti BP. pfungwa iyi vaiita nevarwere. Zvisinei, vamwe vavo vakagunun'una kuti pashure aine mahwendefa mushure mechinguva vakaratidza nemishonga yakadai musoro, muromo yakaoma, kutya uye svoto. Muchiitiko chino, vanachiremba vanokurudzira mishonga kudzima uye kutsiva analogue kwayo, izvo zviri nani utano.