"Paglyuferal" Mahwendefa: mirayiridzo kushandiswa, analogs uye wongororo

Vanhu kutambura nepfari inofanira kugara kutora zvinodhaka antiepileptic. Vanobatsira kudzivirira kukura nezvipusha, uyewo kuvandudza zvinonyatsorehwa utano uye ezvinhu omurwere.

Imhandoi zvinodhaka zvinofanira kushandiswa varwere nepfari, vanofanira kusarudza chiremba chete ane ruzivo. zvinodhaka "paglyuferal" rinoreva inonyatsobudirira uye dzakakurumbira anticonvulsants. Mirayiridzo kushandiswa kwezvinodhaka zvichabviswa kurondedzerwa pazasi. Uchadzidzawo pamusoro fomu umo zvinodhaka ruripo sale, zvinobvira kuti vana vavo chii ehupfumi rine, uye zvichingodaro.

Description, kavha, akafanana uye chimiro

Kugadzirira "paglyuferal" mirayiridzo Chinyorwa iyo iri mubhuku omumasherufu mapepa, riri kutengeswa muchimiro mahwendefa jena beveled uye Valium.

The turusi rine unorapa akadai phenobarbital, zvinhu zvine caffeine yavaibvisa benzoate, bromisoval, karusiyamu gluconate uye papaverine hydrochloride. Kana Excipients, ipapo vanosanganisira mbatatisi starch uye calcium yakawanda stearate.

Kutenga mushonga uyu anogona kuve Maronda akasiyana uye packs it guru bepa, ukuwo.

Zvinofanira kuva pakarepo akataura kuti echiShinto ose Pharmacies gadziriro yakadaro inogona kuwanikwa zvinotevera mazita: "paglyuferal-1", "paglyuferal-2" uye "paglyuferal-3 '. Mirayiridzo yokushandisa inoshuma kuti musiyano nzira ari inorwara phenobarbital (25, 35 uye 50 MG, ukuwo).

pharmacology

Chii chinodhaka "paglyuferal"? Mirayiridzo dzokushandisa (mahwendefa anofanira kuzviita chete ruzivo nyanzvi) rinoti riri kukabatanidzwa antiepileptic zvinodhaka.

Maererano unyanzvi, vaikwanisa kuita ne phenobarbital "barbiturate" mugove neGhebha-benzodiazepine Kanotokonya yakaoma. Nokuda kwaizvozvi, vaiona zvinodhaka kunowedzera aikanganiswa ari neGhebha Kanotokonya kuna neGhebha uye anozivisa neuronal migero kuti kutakurwa kuiisa chlorine ions, nokudaro vachiwedzera kupinda kwavo muzvitokisi.

Uyewo phenobarbital akazoita kupararira tsinga nomunhu uye excitability pamusoro Tutsinga tunofambisa mashoko utwu ari tsviyo chinangwa. It rinoratidza daka pamusoro dzinoverengeka excitatory neurotransmitters.

Ndezvipi zvimwe zvivako zviri kuri kune mapiritsi "paglyuferal"? Guide anoshuma kuti vanokwanisa kudzvinyirira kutsinga dzinouya cortex, kuderera gwenya basa, tunodzivisa chepfungwa basa, kusanganisira kufema centre. Uyewo, mushonga uyu lowers mataurire tsandanyama ari zvomudumbu turakiti, ane antispasmodic, kunyaradza, hypnotic uye antispasmodic chiito.

Features mishonga

Mukuwedzera Phenobarbital, iri kushuma rinoreva zvinosanganisira zvimwe unorapa.

Chii basa zvine caffeine ari chigadzirwa "paglyuferal"? Mirayiridzo yokushandisa kunoratidza kuti nefuma mhoswa kuwedzera dzepanguva excitability kuti musana, fadza kuti vasomotor uye kufema nzvimbo kuti inotokonya metabolic pezvakaitwa vari munyama uye nhengo, kusanganisira tsandanyama uye epfungwa.

Papaverine hydrochloride chiri antispasmodic. It ane hypotensive nomugumisiro. chazvo iri rinoumbwa zvinodhaka uye akazoita tonus pakati kumeso tsandanyama relaxes midziyo ropa uye nhengo dzomukati.

Karusiyamu gluconate anokwanisa kudzikamisa kushaya karusiyamu ions, izvo zvinokosha tsinga chikonzero hutachiwana.

Kana bromisoval, ine mwero hypnotic uye kunyaradza kushanda.

kinetic ehupfumi

It wefodya unopinda muropa zvinodhaka "paglyuferal-1"? Mirayiridzo dzokushandisa chinoratidza kuti mumwe kushingaira chezvinonhuwira mushonga ine kinetic zvinhu.

• Phenobarbital wefodya chose, asi zvishoma nezvishoma (1-2 mumaawa). muviri yaro chiropa. The hafu-upenyu chikamu ichi mazuva 2-5. Iye vaziva kubva mumuviri pedyo neitsvo.
• Zvine caffeine wefodya kwazvo kusvikira muura. The kunonyanyisa Kuwanda nefuma kunoitwa pashure maminitsi 50-75. It rinoita muna chiropa uye kupera vachishandisa neitsvo.
• Average bioavailability ndiyo 54% kubva papaverine. Sezvo anosunga kuti mapuroteni eplasma 90%. Muviri kunoitika muna chiropa, uye ndiye goho kuburikidza neitsvo.
• About 1/5 of dose calcium gluconate wefodya mukati ura duku. Inenge 20% of kwemakemikari kuri nomukombiyuta itsvo uye vakasara - pamwe mutsvina yadzo.

umboo

Izvo zvirwere varayire mushonga akadai "paglyuferal-2"? User chikumbiro inoti kuti uyu nokurapa netsviyo.

Contraindications

Ndezvipi contraindications varipo vari zvinodhaka "paglyuferal"? Mirayiridzo kushandiswa (nokuti vachangoberekwa chokushandisa ichi hazvirevi taurira) rinoshuma zvinotevera inorambidza:

• hyperkinesis;
• chakakomba chiropa uye itsvo kutadza;
• myasthenia gravis;
• zvinodhaka vajairira;
• kuora mwoyo;
• zvakakomba kupererwa neropa;
• hyperthyroidism;
• porphyria;
• rinoita kudhakwa;
• chirwere cheshuga;
• pamuviri;
• hypoadrenalism ;
• lactation;
• broncho-obstructive chirwere;
• hypersensitivity.

Antiepileptic mushonga pamahwandefa raitongwa vana kubva pamakore matatu okuberekwa. With kutarisira Zvinokurudzirwa kuti vanhu vane simba vehurumende (general).

Drug "paglyuferal": mirayiridzo kushandiswa

Viewed medicament chinotarisirwa nomuromo pashure kudya. The dose kunobva kusunungurwa fomu.

Zvinodhaka "paglyuferal-1" uye "2-paglyuferal" tora kaviri pazuva ":

• muna 3-4 Makore - 1 piritsi;
• makore mashanu kana matanhatu kune mapiritsi 1,5;
• manomwe makore mapfumbamwe - 2 bv;.
• gumi kusvika gumi nemana - 3 uye 2.5 yori. ukuwo;
• makore gumi nemana - 4 bv.

Medicament "paglyuferal-3" utore kaviri pazuva:

• manomwe makore mapfumbamwe - 1 piritsi kaviri pazuva;
• gumi kusvika gumi nemana - 1.5 mahwendefa;
• makore gumi nemana - 2 bv.

nemishonga

Rubvumo vaiona mushonga anogona kukonzera:

• zvisipo, utera, dzungu, nystagmus, ataxia, dysarthria, hope nenyonganiso, gangaidzo siyana;
• kupatira, kuda kurutsa, manyoka, ichirova chiropa transaminases, kurutsa;
• thrombocytopenia, agranulocytosis, megaloblastic kupererwa neropa;
• tachycardia, kuchinja BP, arrhythmia, fibrillation, AV blockade;
• systemic neutachiona, zvinodhaka nedoro (chirwere yaitonga).

Zviratidzo ovhadhozi

Yepamusoro mishonga ine medicament kunogona kukonzera amplification divi zvavaifunga. Kubvisa zviratidzo izvi anoshanda:

• gastric lavage;
• symptomatically;
• neactivated charcoal nzira.

zvinodhaka kwavatori

Treatment pavarwere kugamuchira valproate uye "Phenytoin" kunowedzera serum kwevari phenobarbital.

"Paglyuferal" anogona tunodzivisa mugumisiro nomumukanwa nhumbu uye salicylates.

Akabatana "reserpine" zvazviri phenobarbital wakawedzera, uye kana zvasangana "Amitriptyline" "Diazepam", "chlordiazepoxide," "nialamide" uye "acetazolamide" - kunodzikira.

The medicament "paglyuferal" GCS kunoderedza ropa uye anticoagulants, "Doxycycline", "griseofulvin" inonzi estrogen uye dzimwe yomuchipatara izvo vanosangana oxidation ari chiropa.

chinodhaka ichi kuchititadzisa kuitwa sulfonamides, antibacterial basa uye antifungal chaizvoizvo "griseofulvin". Kunze kwezvo, potentiates zvinokonzerwa neuroleptics, panyaya iyi, marwadzo analgesics, tsandanyama relaxants, hypnotics uye sedatives.

Reviews uye analogues

Maererano unyanzvi, kuti mushonga mu mubvunzo rakasiyana nemamwe, zvakafanana akafanana. Naizvozvo, kuritsiva nemazita murwere vanofanira kubvunza chiremba ane ruzivo.

Vatengi vanoti kutenga mushonga uyu usina chiremba mushonga zvikasashanda, kunyange zviri zvikuru inokwanisika.

Vanhu vanogara kutora ichi antiepileptic zvinodhaka, akacherechedza ayo zvakwakanakira. Zvisinei, vamwe vavo vachiri vachinyunyuta pamusoro kwaita vakawanda nemishonga.