Sei "Ibuprofen" (mapiritsi)? "Ibuprofen" - gel, mafuta, kusimiswa: mirayiridzo yekushandiswa, uchapupu. "Ibuprofen" (sira yevana): mirayiridzo yekushandiswa

Sei Ibuprofen yakanyorerwa varwere? Tichakuudza pamusoro peizvi munyaya yakataurwa. Kubva mauri uchadzidza nezvemaitiro ayo chibereko chacho chinogadzirwa sei, sei uye mumatanho api anofanira kutorwa, nezvimwe zvakadaro.

Kuumbwa, kugovera, tsanangudzo, maitiro emishonga

Ibuprofen akabudiswa mumhando ipi? Mirayiridzo yekushandisa, kuongororwa kwevanyori vanotaura kuti ichi chinodhaka chinogadzirwa nenzira dzakasiyana-siyana.

• Biconvex uye mahwendefa akapoteredza zvinotengeswa mumakadhibhopu mapeji makumi maviri, gumi kana zana. Vane bhenekeri pamusoro uye nemuchena mutsvuku. Nhengo inoshanda yechirwere ichi ibuprofen.
• Mahwendefa-akafukidzwa "Ibuprofen". Kubva pane izvo mahwendefa aya, tichataurira zvishoma. Izvo zvinosanganisira zvishoma zvechikamu chinoshanda, nokudaro kupa chiito chenguva refu.
• Capsules. Iyi fomu ine 300 mg yekubata zvinhu. Vanopera zvishoma nezvishoma.
• Kusimudzirwa kweIbuprofen. A syrup yevana inouya kuzotengeswa muhombodo ine kapu yokuyeresa. Kuvhiringidzika uku kwakafanana nehukuru hwejvara ruvara. Inogona kuva nemaruva uye sitirobi kunhu.
• Suppositories Ibuprofen. Mirayiridzo, maitiro anotaura kuti makenduru akadai anoshandiswa rectally. Zvinotengeswa mumapakiti ezvimedu 10.
• The granules. Iyi fomu inogadzirirwa kugadzirisa mishonga yemishonga yekugadzirisa mumuromo. Chigadzirwa chakapedzwa chine mint flavor, pamwe nekunhuwirira kwakanaka.
• 5% "Ibuprofen" mafuta. Kushandiswa kwechibvumirano ichi kunokubvumira kubvisa marwadzo mumisungo nemasangano. Iyo gel inoshandiswa chete kunze.
• Solution for injection. Iyo inobudiswa muGermany uye inotengeswa mu cardboard packs ye 4 capsules. Pinda mishonga iri mukati.

Zviratidzo zvemishonga yemishonga

Sei Ibuprofen ishandiswa mukurapa? Maererano nemirairo, iyi mishonga isiri-steroidal anti-inflammatory drug. Inokwanisa kuva ne-anti-inflammatory, antipyretic and analgesic effects. Nyanzvi dzinoti chirwere ichi hachigadziri kuvhara COX2 uye COX1.

Nheyo ye ibuprofen ndeyokuderedza kushandiswa kweprogaglandins, kureva, vamiririri vekuputika, kurwadziwa uye hyperthermia.

Pharmacokinetics yezvinodhaka

Ndeapi ma pharmacokinetic mapiritsi anoita mahwendefa eIbuprofen ane? Kushandiswa kwemazwi emumuromo wemishonga inopa huwandu hwepamusoro uye hunokurumidza kubva pamagetsi.

Iyo yakanyanya kukamiswa ye ibuprofen mu plasma inoonekwa pashure pemaminitsi makumi maviri nemakumi mana nemashure mushure mekutonga kwayo. Kubatana kweplasma mapuroteni kunopfuura 90%, uye kupera hafu-hupenyu maawa maviri.

Mushonga we "Ibuprofen" (kusungirirwa uye mahwendefa) zvishoma nezvishoma zvinopinda muzvikamu. Chinhu chacho chinoshandiswa chinowanikwa mu synovial tissue. Izvi zvinopa iyo nekufunganya kwakakura kwezvigadzirwa zvinoshanda.

Mushure mokudya, inenge 60% yekusakosha R maitiro emushonga inochinjwa kuva S-fomu inoshanda.

Ichi chirwere chinoshandiswa. Yakanyanyisa kuburikidza neitsvo (isina kuchinjwa), uye pamwe chete ne bile.

Zviratidzo zvekushandiswa kwemhando ipi zvayo yemishonga

Nei ibuprofen inogona kurairwa kune varwere? Maererano nemirayiridzo, ichi chinodhaka chine zviratidzo zvinotevera zvekushandiswa:

• Zvirwere zvepamusoro uye masangano anopisa (kusanganisira ankylosing spondylitis, arthritis rheumatoid uye gouty, osteoarthritis);
• Febrile syndrome, iyo inopesana nechemberi kwezvirwere zvinotapukira kana catarrha;
• Matambudziko mashoma ematambudziko akasiyana-siyana (kusanganisira misoro, neuralgia, migraine, kurwadziwa kwemashure, mazino, myalgia, algodismenorrhea primary, post-traumatic pain).

Ndezvipi zvimwe zvinangwa Ibuprofen zvinogona kushandiswa? Ko mahwendefa aya anorayirai kuvarwere? Vanachiremba vanoti izvi zvinodhaka zvinoshandiswa zvakashandiswa pakurapa zviratidzo. Zvakanaka uye zvakakurumidza kugadzirisa kupisa uye kurwadziwa (chete panguva yekushandiswa), asi kufambira mberi kwechirwere hakuiti.

Contraindications for use

Nokuti "Ibuprofen" inoshandiswa nevarwere, isu takatsanangura pamusoro apa. Nezvokupikisa, zvinosanganisira zvinotevera zvemu murwere:

• Zvirwere zvinokonzera uye zvinouraya zvegumbo rekudya, kunyanya muchitambo chekuwedzera (somuenzaniso, ulcer we 12-типерстной gut, mudumbu, Crohn's disease, ulcerative colitis nonspecific);
• Hypersensitivity yemunhu kune zvinoshandiswa zvinoumba mishonga;
• Hypersensitivity yemurwere kune acid acetylsalicylic, pamwe nedzimwe NSAIDs, kusanganisira anamnestic data pamusoro rhinitis, kudzivirira kwechirwere, mikoko pashure pokutora NSAIDs kana acetylsalicylic acid;
• Zvirwere zvepamuviri zvechimiro chekuvhiringidza;
• Chirwere chisina kukwana kana chakakwana chekusagadzikana kune acetylsalicylic acid (inoratidzwa nenzira ye rhinosinusitis, urticaria, polyps mu mumasasa emusana, maronchial asthma);
• Period mushure mekugadzirisa arteri kupfurikidza nekubatanidza;
• Hemorrhagic diathesis, hemophilia nezvimwe zvinetso muropa coagulability (p., Hypocoagulation);
• Kurwara kusina kufanira kwakaratidza, zvirwere zvakasiyana-siyana zveropa;
• Kuita zvirwere zvinoputika, kubuda kwepamuviri ropa;
• Kukundikana kwemashizha kwakaratidzwa, kwakatsigira hyperkalemia;
• Chirwere chepfungwa chinopfuurira.

Ndezvipi zvimwe zvinopesana zvinowanikwa kune zvinodhaka Ibuprofen? Sirasi yevana haina kukurudzirwa kupa vana kusvika mwedzi mitatu, uye mamwe maitiro emishonga - kusvika kumakore matanhatu. Uyewo, mushonga uyu haufaniri kushandiswa panguva yekuzvitakura.

Kucherechedza kugamuchira

Ndezvipi pasi pemamiriro ezvinhu anofanirwa kushandisa ini mushonga "Ibuprofen" nekuchenjerera zvakanyanya? Kushandisa (kubvunzurudza pamusoro peizvi zvichazobudiswa gare gare) zvechirwere ichi kune vakwegura, pamwe chete nevanhu vane mwoyo wakakundikana, chirwere chepfungwa chepamusoro uye chinonzi ischemic heart chirwere chinofanira kunyatsodzorwa nechiremba.

Uyewo, nekuchengetedzwa kwakanyanya iyi mishonga inorayirwa kune zvirwere zvinokonzerwa nehutachiona, dyslipidemia, chirwere cheshuga, zvirwere zvinokonzerwa nehutachiona (pwere), kusvuta, kupinda mukati, kunwa doro nguva dzose, chiropa chinonzi cirrhosis, gastritis, nephrotic syndrome, hyperbilirubinemia, colitis, zvirwere zveropa zvisingazivikanwi uye panguva yemazamu Kudyisa.

Nzira dzokushandisa mushonga

Nzira dzekushandiswa kwegadziriro iyi dzinobva kune maitiro ayo ekubudiswa.

• Syrup.

Ibuprofen inoratidzirwa kuvanai? Mirayiridzo yekushandisa inotaura kuti, maererano nemapiritsi, sirasi inoita zvakakurumidza. Usati washandisa iyo fomu, bhodhoro rinofanira kuzununguswa zvakakwana. Muyero wemishonga iyi inofanira kuongororwa chete nevanachiremba, zvichienderana nemamiriro emurwere.

• Makandulo.

Zvinyorwa "Ibuprofen" zvakasikwa zvakanyanya kune vacheche. Dzinoshandiswa rectally uye dzinotanga kuita mushure maminitsi makumi matatu. Ne febrile kana chirwere chinorwadza, chirwere chimwe chete chemushonga uyu chinokwana 5-10 mg pa1 kg yehutakadzi hwemwana. Isa ma kenduru zvichida panguva dzemaawa matanhatu nemaawa matanhatu.

• Gel, mafuta.

Ndinofanira kushandisa sei mafuta eIbuprofen? Gel, ruvara rwe 1.5 cm, rinoshandiswa kune chiremera chine kumira kwemazuva. Inofanirwa kuve yakangwarira kudzivisa kuwana mishonga mumuche uye maronda akazaruka. Kana zvisina kudaro, mushonga wacho unofanira kushambidzwa pakarepo nemvura inodziya.

• Mapiritsi.

Ndiyo mapiritsi "Ibuprofen" anokuvadza vana here? Mirayiridzo yekushandisa inotaura kuti iyi fomu yemishonga haifaniri kupa vana kusvika kumakore matanhatu.

Tora mishonga iyi inofanira kuva pakati pekudya. Kazhinji inorayirwa muwandu we 5-10 mg pa 1 kg yehutatu hwomunhu katatu pazuva. Muchiitiko ichi, chirwere chezuva nezuva hachifaniri kunge chinopfuura 20 mg pa kg.

Ne rheumatoid arthritis, pamwe chete nedzimwe zvirwere zvezvibatanidza, mushonga unorayirwa muhuwandu hwe 40 mg / kg (asi kwete kupfuura).

Mhosva yekudarika

Kana uchinge uchitora madhadhi akakwirira emurapa, murwere anogona kuwedzera zviratidzo zvinotevera: kuora mwoyo, kuvhara, kurwadziwa mumimba, kurara, kusuruvara, tinnitus, kuora mwoyo, metabolic acidosis, kuora musoro, kushaya simba kwemazino, coma, bradycardia, kuderedza ropa, fibrillation Atrial, kuporesa kusungwa uye tachycardia.

Kurapa - kukurumidzira gastric rinopisa (mukati memaminitsi 60 mushure mekudarika kwepamusoro), kugamuchirwa kwekabhoni, soro realkaline uye diuresis yakamanikidzwa.

Migumisiro Yechiri

Ko kugadzirira "Ibuprofen" kunobatsira here kuitika kwekusateerera kwakashata? Gel kushandiswa kwekunze hakuna kumbokonzera migumisiro isina kunaka. Kana iri yemhando yemuromo yemishonga, inogona kukonzera zvinotevera:

• Dambudziko remuviri, kuderera kwechido, kusuruvara mumuromo, kurutsira, kurwara kwemucosa, kuora mwoyo, aphthous stomatitis, chirwere, kuoma kana kutsamwa kwezwi mumcosa, flatulence, pancreatitis, kuvimba;
• Hepatitis;
• Bronchospasm, dyspnea
• Kunzwa kuora mwoyo, ruzha kana kuchera munzeve, kunzwa kurasikirwa;
• Hashariswa uye maziso akaoma, scotoma, zvinokonzera tsvina dzemagetsi e-optic, kuwedzera kusina kujeka kana kuora kwemaonero, edema emawere emaoko uye conjunctiva;
• Kushushikana, kuora musoro, kufungidzira, dutu, kuora mwoyo, kuzvidya mwoyo, kuora mwoyo, kusuruvara uye kutya, kubotsira, kuputika kwepfungwa, aseptic meningitis;
• Tachycardia, mwoyo kusakundikana, kuwedzerwa kweropa;
• Kukundikana kwakanyanya kweainal, polyuria, allergic nephritis, nephrotic syndrome, cystitis;
• Kushanda kweganda, Quincke's edema, pruritus, exudative erythema multiforme anaphylactoid reactions, fever, anaphylactic shock, dyspnea, bronchospasm, Stevens-Johnson syndrome, eosinophilia, epidermal necrolysis toxic, allergenic rhinitis;
• Kuwedzera kwekutuka;
• Anemia, thrombocytopenic uye thrombocytopenia purpura, leukopenia, agranulocytosis;
• Kusuruvara kwemuviri mucosa, kubuda ropa.

Inofanirawo kuonekwa kuti kutora mishonga iyi kunogona kuchinja mhando dzinotevera ma laboratory:

• Serum creatinine concentration (yakawedzera);
• Kubvisa nguva nguva (kuwedzera);
• Kuchenesa kwe creatinine (kunoderera);
• Serum glucose (concentration);
• Hemoglobin kana hematocrit (inogona kuderera);
• Chiitiko chechiropa transaminases (kuwedzera).

Kana kukanganisa kwakadaro kuchiitika, iwe unofanira kumira pakarepo kutora mishonga uye taura nachiremba.

Mazano Anokosha

Kurapwa nemishonga "Ibuprofen" inofanira kuitwa muchidimbu chiduku, izvo zvicharatidza maitiro ekurapa ekurapa. Nzira yerapi inofanira kuva shoma.

Kana kurapwa kuchiitwa kwemazuva mazhinji, zvinodiwa kuti iongorore itsvo uye chiropa, pamwe chete nemufananidzo wehutachiona ropa.

Apo zviratidzo zvegastropathy zvinoratidzika, kuchenjerera kutarisa mamiriro emurwere kunokosha. Inofanira kusanganisira esophagogroduodenoscopy, pamwe chete nemafuta emashiripiti uye kuongorora ropa (kuongorora hemoglobin).

Kubatana Kwemishonga

Izvo zvisingadikanwi kuunganidza mushonga weIbuprofen ne acetylsalicylic acid uye dzimwe NSAIDs. Izvi zvinokonzerwa nekuti iyo inogona kuderedza kupesana nekuputika uye antiplatelet migumisiro yemishonga iyi.

Panguva imwechete yekugamuchira mishonga inofungidzirwa ne thrombolytic uye anticoagulant magadzirira chiitiko chekusimudzirwa kwemafupa kunomutsa.

"Cefaferazone", "Cefamandol", valproic acid, "Cefotetan" uye "Plikamycin" inowedzera mikana ye hypoprothrombinemia.

Zvinodhaka zvinodzivisa kupfigira kweputi, zvishoma nezvishoma uye kuwedzera majekesa epurasma yeIbuprofen.

Ichi chinodhaka chinowedzera kukanganisa kwemishonga yemishonga, inowedzera migumisiro yekunyoresa anticoagulants, fibrinolytics uye antigregregants.

Mhinduro dzevarwere pamusoro pemishonga

Mushonga we "Ibuprofen" unozivikanwa kwazvo pakati pevarwere. Iyo yakagadzirirwa senhare inoshanda inopesana nekuputika, iyo ine maitiro akawanda ekubudiswa.

Maererano nemhinduro dzevarwere, iyi mishonga inotanga kuita zvakakurumidza. Inobvisa kunyange kurwadziwa kwakanyanya muzvibatanidza nemisungo, uye kunobvisawo misoro uye kuputika kwezvakasiyana-siyana.

Nharo yega yemishonga iyi ndeyekuvapo kwehuwandu hwemigumisiro uye zvinopesana. Maererano nekurongororwa kwevarwere, mushonga we "Ibuprofen" unowanzokonzera kurwadziwa kwepamuviri, kusuruvara, chirwere uye kurutsira, uye kunokonzera kuonda uye kuora mukati mutsva yematumbo. Saka, shandisa mishonga iyi inokurudzirwa mumadhesiti maduku, uyewo kwenguva pfupi. Munzira iyi iwe unogona kubvisa marwadzo syndromes uye panguva imwe chete usingafungi maitiro ega.