The follicular phase of the menstrual cycle

The follicular phase ndiyo chikamu chekutanga chekuvhara mazai, iyo inoratidzwa nekukura nekutsvaga kwehupfumi.

Iro follicular phase kana, sezvinonziwo, estrogen, inotanga kubva pazuva rokutanga rokutanga kuenda kumwedzi uye rinogumira kusvikira mavha mavari anokura imwe kana kuti yakawanda inowanikwa follicles. Kuguma kwechikamu ichi kuve-ovulation.

Nguva yaro inogona kunge yakasiyana zvachose. Kazhinji kacho, kunonoka kwekuenda kumwedzi kunowanikwa nenzira chaiyo nekuda kwekureruka kwekutsvaga kwehupenzi. Chinhu chinokosha chinokanganisa kukwana kweiyo nzira ndiyo nguva inotarisirwa kuti muviri upike kusvika pamiganhu yeestrogen.

Maererano nekushanda uye morphological changes mu ovary, mutambo wegore negore unogona kugoverwa muzvikamu zvakadai:

1) The follicular phase;

2) Ovulatory;

3) Luteal;

4) Kuenda kumwedzi.

Chikamu chekufamba-famba kunotungamirira kuhutano kunonzi follicular. Kazhinji zvinongotora hafu yekutanga yekufamba, asi dzimwe nguva inogona kugara kwenguva refu. Ivhareji yehupenyu nguva ndeye mazuva makumi mana. Chero kusvibiswa kubva pane nhamba iyi kunokonzerwa chete nekureba kwenguva ye follicular phase.

The follicular phase inoratidzwa nekuwedzera kuwedzerwa kwepakati uye kusunungurwa kwe inhibin uye estradiol. Uyezve, kuwanda kwemahomoni aya hakuwedzereri mukushambadzira kwe systemic, asiwo mu follicular fluid. Pane imwe mazuva maviri kusati kwasvika kwekuenda kumwedzi kunotanga kukurudzirwa kweporolicle kubva pakuzorora kwayo kana kuti chimiro chikuru.

Nenguva ino muhutari, iyo yemaviri muviri inouraya , iyo yakaumbwa munguva yakapfuura. Chigumisiro cheizvi ndechekuderera kwakapinza mumusana weestradiol, progesterone uye inhibin (yekupedzisira maviri kusvika zvishoma).

Mumazuva 4-5 echikamu chino, mavambo makuru evarian follicles vanoramba vachienda uye vanoramba vachizorora. IHollicle-stimulating hormone (FSH) inotanga kukonzera kupararira kwemasero, ayo basa rawo rinowedzera. Mhedzisiro inowedzera mukuumbwa kwe androgens kubva kune estrogen, iyo inogadzirwa nemasero emagetsi.

Kubatanidza follicles panguva ino kazhinji hauna imwechete yemasero follicular akapoteredza oocyte. Mukuwedzera, kuunganidza kuduku kwe follicular fluid kunooneka pakati pemasero aya. Iyo hormone inopisa-inotanga inotanga kukurudzira kuonekwa kwehuwandu huwandu hwezvinyorwa zveLH nezvayo zvinogamuchirwa. Uye izvi zvinowedzera kushushikana kwaro hormone luteinizing.

Iro follicular phase inoratidzwawo nezvokuti musi wechitanhatu wechitanhatu wechinomwe humwe hwemaperembudzi anobuda anotanga kutonga. Iyo inongoramba ichiwedzerwa uye mushure mokunge ovulating inenge yezuva 13-15 hwekufamba. Iko inonzi follicle yakakurumbira inoratidzwa nepamusoro-soro mitotic ye follicular cells, iyo yakakwirira yakawanda ye follicle-stimulating hormone mu follicular fluid.

Zvisizvo zvinoratidzira follicles zvinowedzera kuwedzera kwe androgens uye estrogen, uye izvi zvinoratidza kuti basa re aromatase rakaderedzwa mu follicular masero. Zvinyorwa izvi zvisina simba zvinotungamirirwa ne reverse development (atresia). Androgens ndiyo chinhu chinonyanya kukosha mukududzirwa kweatresia.

Iyo yakaderera uye yepakati follicular chikamu chekuenda kumwedzi inoratidzika nekuwedzera kukura kwekushandiswa kwe inhibin B uye estradiol, uye izvi zvinotadzisa kugadziriswa kwema follicle-stimulating hormone neye pituitary gland uye kukura kwe follicles matsva kunoguma. Kuwedzera kwezvakanyorwa zve-estradiol kunotungamirirawo kuwedzera mukuchengetedzwa kwemakironi emakondomu uye kuwedzerwa kwehutano hwehuvha kusvika kune gonadotropins. Mukuwedzera, chiyero cheestrogen chakakonzera kukura kwe endometrium. Kuchinja kwakadaro kunonzi "chikwata chekuwedzera".