The mushonga "Concor VaK": zvairatidza kuti kushandiswa, dzomuzana chaiwo

Zvemwoyo vava zvinenge pakutanga muna mwero wokufa kwevanhu munyika. Uye nezvinetso izvi kuwana muduku ose gore. Kana yapfuura pamusoro myocardial infarction iwe wakati, raiva mubvunzo pamusoro pemakore dzinenge 45-50 makore, nhasi chirwere ichi rungatora, uye-makore 30.

Modern Pharmacy ane vakawanda medicaments kuti tirwise matambudziko "cardiac" panguva mumatanho akasiyana-siyana okukura zvirwere izvi. Rimwe boka zvinodhaka izvi Beta blockers. Nheyo kushanda mari idzi kuti adzikatidza Beta-adrenergic receptors mumwoyo. Mugumisiro uri kuderera mumoyo zvazvingava, iyo inotungamirira tikarega BP uye kuvandudza mukuru mamiriro ezvinhu munhu.

Beta-blockers zvino vakava zvakasiyana zvikuru. Imwe zvinowanzoshandiswa pokumuka matambudziko cardiac ndiye "Concor VaK." Zvinoratidza, wongororo kuti medicament munguva mushonga kuti zvakakwana runziro uye vanoda pakati varwere cardiac chirwere.

Huru zvinoriumba uye chimiro zvinodhaka yokusunungurwa

The chikuru chezvinonhuwira kugadzirira "Concor VaK" - bisoprolol hemifumarate. Ebetsero makabuda zvakakwana guru mazita zvinhu: zviyo starch, microcrystalline cellulose, crospovidone, magnesium stearate, colloidal nesilicon dioxide, anhydrous karusiyamu rehydrogen phosphate.

The mushonga runopiwa vatengi muchimiro chena film-zvemapuranga mahwendefa mwoyo-zvemapuranga (mu kwayo sezvamunoita - macrogol 400, dimethicone 100, gipromelaza, titanium yakasviba). Risk kumativi ose rinokamukana mu mahwendefa maviri "Concor VaK." Kavha medicament anogadzirwa foil Maronda akasiyana, rimwe nerimwe anogona soldered zvidimbu 10, 14, 25 kana 30.

Varwere vari kakawanda kuonekwa Pharmacies uye mushonga "Concor". Sezvo mazita aya mishonga maviri akafanana chaizvo, kazhinji vemishonga kupindura mibvunzo pamusoro musiyano "Concor" kubva "Concor VaK." Saka: musiyano chete iri uwandu zviri huru vanoshingaira zvinoriumba - bisoprolol. "Konkor" vatengi anogona kutenga mahwendefa ane ayo sezvamunoita iri 5 kana 10 MG kuti vanoshingaira chirungiso, apo "Konkor VaK" - 2.5 MG.

Vachizvida kuziva kuti kutenga mishonga-blockers mu chemishonga iri mishonga vanofanira kupa yachiremba mushonga.

pharmacodynamics

"Concor VaK" ane zvokusarudza Beta 1-adrenoceptor ichivharira simba. Musimboti zvachinokonzera - kukwanisa kudzvinyirira nokubata tsinga nomunhu ari adrenergic receptors. Nekuda kwechikonzero ichi mushonga anokwanisa kushanda antihypertensive, antiarrhythmic, antianginal migumisiro.

Vane chirwere cheBP chaizvoizvo "Concor VaK 'wongororo vanachiremba chokuita chokuti bisoprolol akazoita miniti vhoriyamu ropa. Uyezve, yakafanana chinovhiringidza akaita renin-angiotensin hurongwa. Mukuru kunotoda kushanda kunoitwa pashure 5 mazuva kugamuchira zvinodhaka. BP iri kudzikamiswa pakazopera mwedzi mishonga kurapwa chechipiri "Concor VaK."

Ppokazaniya medicament kushandiswa sezvo zvinovimbisa akatsiga antianginal migumisiro nokuderedza myocardial okisijeni kudiwa nokuda kuderera kwemwoyo. Uyewo, ndinofanira kutaura kuti kushandisa mishonga iyi inosimudzira prolongation kuti diastole.

Antiarrhythmic zvazviri rinoreva "Konkor VaK" nokuda ichivharira zvakaipa kupesvedzera zvinhu izvo zvinosanganisira rushoma pokudzora tsitsi kudzvinyirira pakati CNS Department, kudzvinyirira pezvakaitwa asike nemagetsi pulses ari sinus raiva pedyo nebundu, ari chinovhiringidza pakati Kugwina myocardium.

Kuti aratidze zvinodhaka, uye ndiani - kwete?

Ndezvipi zvinoita panguva "Concor VaK" zvairatidza kuti kushandiswa? Consumer ongororo zvisimbiswe yakakwirira kunyatsoshanda zvinodhaka. Zvinokurudzirwa kuti kutora kubata mwoyo nokukundikana uye kudzivirira kukura ezvinhu akadaro tanga. Kuti kuva chaiwo, vashandi utano varayire mashoko Beta-blocker kubvuma kurapwa nemishonga chisingaperi mwoyo kukundikana pamwe akaderedzwa rworuboshwe ventricular systolic chaitika. Kazhinji "Konkor VaK" nezvaro kufanana ACE FIs , diuretic vamiririri, cardiac glycosides.

Kuti hapana aiva nechido kupa mushonga pachayo pachavo, pasina chiremba wenyu mirayiridzo, zvinokosha kuti kuzivana anoyevedza mazita contraindications kuna nevasori "Concor VaK."

Kunze rokumanikidzirwa vose mishonga mirayiridzo kurambidza pamberi asingashiviriri kuti hurongwa hunoumba zvinodhaka uye murwere zera (makore anosvika 18 zvichibatanidzwa - hapana ruzivo pamusoro kubudirira uye kuchengeteka), kuchine zvakawanda zvikonzero uye mamiriro pasi izvo zvinodhaka chinobviswa nezvisingabvumwi.

"Concor VaK" mirayiridzo kushandiswa (analogues - yemhando Beta-blockers - vane mirayiridzo yakafanana iri inadmissibility kuti kubvuma) unorambidza varwere mwoyo kukundikana chakasimba uye chirwere decompensated insufficiency. Regai gadzai zvinodhaka womuchato iri kuparara uye cardiogenic kuvhunduka (chirwere kukonzerwa cardiac dysfunction). Mumwe haagoni kutora Beta-blocker kuti hombe zvarakasiya ose AV-conduction (II, III dhigirii AV-chigumbuso) pasina chinodzora kurova. Uyewo chikonzero chokuramba kugamuchirwa ndiyo kuvapo bradycardia (kwemwoyo (kwemwoyo) iri asingasviki 50 anorova / min.), Sinoatrial blockade (achiipa sinus zvechivhurumukira achipfuura sinoatrial mukomboni). Mishonga contraindicated pavarwere vane Prinzmetal angina (spasm rwengarava kuti zvokudya mwoyo, apo ST chidimbu elevation) uye kurwara sinus syndrome (SSS).

Musatora "Concor VaK" ne pasi systolic BP (pazasi 90 mm Art HG..), Pamberi asima kwazvo chimiro, avo vane nhoroondo yenhau chisingaperi obstructive pulmonary chirwere (COPD).

Uyezve kugadzirira "Konkor VaK" kushanda nezvisingabvumwi pamberi abnormalities munyika peripheral kweropa maitiro (kunyanya chokuita papera nzendo) nehosha Raynaud raMwari, pheochromocytoma (benign kana akaipa bundu APUD-maitiro), uye metabolic acidosis (kuchinja kwezvinhu asidhi-hwaro mwero yakananga kuwedzera acidity nokuda kuunganidza acidic zvigadzirwa vari munyama dzavo ndichisunga kana kusava kuparadza).

Marapirwo zvaiitwa uye bvumidzwa vhoriyamu bisoprolol

Maererano mirayiridzo, iyo Beta-blocker chinobviswa kamwe pazuva, kunyanya mangwanani, pashure kudya. Mapiritsi "Concor VaK" (kubva chii yaizova mishonga haina kushandiswa - kana ischemic mwoyo chirwere, chirwere chemwoyo, kana neBP) havafaniri kutsenga kana kuvatsakatisa akamedza rose uye ndikandoshamba pasi shoma mvura.

Kuti aite kuchirapa matanho kuti chirwere chemwoyo pamwe nokushandiswa kwezvinodhaka "Concor VaK" Zvinokurudzirwa kuti vaite titration ari dose. Musimboti mutoo sezvinotevera: mukati 1 ST vhiki vakagamuchira huwandu Beta-blocker tichitarisa bisoprolol ndiyo 1.25 MG 2-vhiki dose kaviri (2,5 MG) kwemaminitsi 3 3.75 MG. Munguva kubva 4th vhiki kusvikira pakuguma 7th dose ndiyo 5 MG daily Bisoprolol; 8 fung vhiki kusvika 11 ndipo - 7.5 MG. Kutanga kubva rechi12 vhiki akabvuma vaifanira 10 MG. The chipimo chemushonga zvinokosha (uye zvichiita) kuwedzera kungoita nechokwadi chokuti yapfuura anowanzoitwa akashivirira uye haakonzeri seasingabatsiri.

Pano panyika - ndivo mhinduro yomubvunzo wokuti pane "Konkor" rinosiyana "Konkor VaK": wechipiri musiyano wezvinyorwa (2,5 MG bisoprolol) rakanakira kutanga kuchirapa matanho panyaya kuramba chisingaperi mwoyo nokukundikana rinoti, apo wokutanga (5 kana 10 MG) ndiyo yakakodzera yokuzvigadzirisa kurapwa.

Kana pane dzimwe nguva pakanga dose kuchinja mwoyo nokukundikana zviratidzo, nyanzvi dzokurapa dzinokurudzira yakarurama chipimo chemushonga yacho yakafanana diuretics kana ACE FIs. Kana kwapera nguva kuwana chinzvimbo kuvandudza, zvinokosha kuramba chirongwa titration "Concor VaK."

Zvipatara pamwe kwezvinodhaka uyu kwenguva refu hunhu. The abolition of Beta-blocker zvinofanira chinozoiswa zvishoma nezvishoma, kunyanya varwere vanenge ischemic mwoyo chirwere.

Kunwisa mishonga: zvinokonzerwa uye kurapwa

Mirayiridzo kuti mushonga nguva dzose rinoperekedza piritsi "Concor VaK." Kubva dzavanoshumira kutora ndedzipiko contraindications, izvozvo inorondedzerwa kare. Zvino tichakurukura zvokuita kana, nokuti vamwe chikonzero, nezvisingabvumwi guru dose yatorwa.

Symptomatology ari sezvinotevera: kuva neBP uye bradycardia, bronchospasm, uye yakakwirira ndingangokuvara yomuropa anogona kutanga rikwanise mwoyo kukundikana.

Migumisiro nokugamuchira guru mishonga vanhu vakasiyana zvingasiyana zvokunyama. Zvichida, vaya vanotambura mwoyo kukundikana, dzine hanya zvinopfuura zvavakabvumirana chipimo chemushonga nachiremba wako. Chisarudzo chakanakisisa kuti murwere - kuona chiremba (kana zvichibvira kuzviita pachako) kana kukonzera "kutsanya". Zvichienderana papi mushonga rave kugamuchirwa, chiremba achasarudza matanho kuendeswa aivabatsira murwere ezvinhu.

Sezvo nokukurumidza zvinhu raiwanzoitwa gastric lavage uye negashiro absorbents (kusashanda kabhoni kana ayo analogues). Uyezve, zvichienderana nemamiriro ezvinhu, bisoprolol kurapwa kunogona akamiswa uye nokuda zvaida nguva nguva, muchipatara achakutsigira uye symptomatic kurapa.

Mirayiridzo "Concor VaK" zvairatidza kuti kushandiswa, zvokurapa nezvaro uye mamwe manyuko mashoko vakauya pfungwa nyanzvi uye vatengi kuti bisoprolol zvakaoma zvakakwana amenable kuti dialysis.

Negative kuratidzwa Chikumbiro "Concor VaK"

Sezvo chero mushonga, anokwanisa kupa "Concor VaK" nemishonga kunosiyana kuchinyanya pazuva hurongwa uye zvomukati.

With Panyaya kumwoyo, kupfuura kakawanda zvichemo dzevarwere pamusoro panowanikwa bradycardia uye BP (kunyanya vanhu vachitambura nekuora mwoyo nokukundikana), anogona kuva vasospasm. To muduku zvakadini zvingangodaro kuputsa AV-conduction, cardiac decompensation, achiperekedzwa peripheral edema.

Maonerwo Akaitwa CNS mushonga rinowanika zvishoma raidudzwa uye anogona kuva kuneta, nomusoro uye dzungu, kurukutika, hope chinovanetsa, uye nguva takamuka. Very kashoma, varwere chokunyunyuta pamusoro chinyamunhari chinorwadza, kurota zvinotyisa uye fungidziro. Kazhinji, zviratidzo izvi havana dziberekane zvikuru uye kuedzwa pashure pemavhiki 1-2 kubva pakutanga yokurapa ne "Concor VaK."

Zvairatidza kuti kushandiswa uye mazita contraindications zvinoomerera pfungwa varwere vane nhoroondo mashoko COPD uye asima, pane mukana bronchospasm. Kashoma kutaura zvakafanana sema rhinitis.

Pamusoro chikamu zvomudumbu turakiti kazhinji zvingakonzera kuda kurutsa, kurutsa, kupatira, manyoka, kunzwa kuoma kwakaita mucous mune nemumuromo mhango. Nezvahwo taura pamusoro kukura nehepatitis uye kuchinja mune chiropa makemikari.

Kuwedzera ose apa, varwere dzinoshuma kutarisana vachivavhiringidza uye conjunctivitis (zvisingawanzoitiki), pamusoro chinyamunhari chinorwadza ari mhuru tsandanyama uye tsandanyama simba, zvaipesana potency (kushoma chaizvo).

Of neutachiona kazhinji zvinoita mapundu, kuvaviwa uye akatsvuka.

"Concor VaK" uye pamuviri

Beta-blocker "Concor VaK" panguva pamuviri zvinogoneka chete zviitiko apo akatarisirwa zvinobatsira amai utano hwake kupfuura zvingakanganisa kukura kwemwana.

Chero Beta-blockers (uye "Concor VaK" pakati pavo), kuderedza ropa riyerere ari placenta uye nokudaro angava inokanganisa kukura mucheche utero. Kana uchiri basa kugamuchira pamuviri mishonga, vashandi vezveutano vanofanira kuramba kuongorora ropa riyerere ari placenta uye dumbu, uyewo kuchengeta kukura mwana. Mune chiitiko upi akaipa zvikonzero mukadzi uye mwana kunofanira pane dzimwe, dzimwe nzira kurapwa.

Pashure pakaberekwa mwana anofanira nyatsonzvera. Panguva 3 mazuva mwana anogona kuderedza padanho shuga muropa wokutanga, zvingadarowo bradycardia (akaderedza kwemwoyo) zviratidzo.

Sezvo vakadzi kuyamwisa, kuti mugove mashoko ose bisoprolol pamwe mukaka kana kuchengeteka kwayo haisi kuwanikwa mwana. Naizvozvo, kana zvakakodzera, vanogamuchira rinoreva "Concor VaK" iyi, zvakakosha kuti kusarudza kugumiswa lactation.

zvinodhaka zvakafanana

Muna mushonga "Concor VaK" dzomuzana (izhinji) kunowanzoitwa iri huru vanoshingaira chirungiso - bisoprolol. mishonga Self anogadzirwa Germany uye Norway. mishonga akadai "Aritel" zvinowanzoshandiswa pakati dzomuzana Russian, uye "Aritel VaK", "Biprol", "bisoprolol-Prana". Kunyange zvazvo yokupedzisira rinowanika munyika dzakawanda pasi pose, "bisoprolol din email" - Hungary, Israel, "bisoprolol-dzichiitirana" - Ukraine. Chaizvoizvo, zvakananga analogue ndiye "Concor".

Uyezve, kubva inonyanyoshandiswa vakashandisa nzira yakafanana anogona kunzi "Bidop" uye "Bidop VaK" "Biol" "Bisogamma", "Bisomor", "Kordinorm" uye "Kordinorm VaK", "Tiresias", "Niperten".

Kazhinji, pamazita analogues (anoreva zvakafanana) rakanyatsojeka rakafara uye yakasiyana-siyana, asi kugadzirisa mubvunzo chii kutsiva "Concor VaK" kuzvidzora isingagamuchiriki. The rworudyi kusarudza medicament nokuda yokutsiva ndokwaJehovha chete kupinda chiremba.

Kudyidzana nevamwe zvinodhaka

Zvakanaka efficacy uye tolerability kuti Beta-blockers zvingaita kushandiswa zvinodhaka maviri panguva imwe chete. Maererano mushonga "Concor VaK" (zvairatidza kuti kushandiswa, chaicho utano vashandi uye varwere zvinoratidza maitiro akadaro) kusashivirirana anogona kuitika kunyange kana zvakafanana pfungwa simba zvinodhaka atorwa kuburikidza shoma nguva mumwe.

Uyezve, varwere vachitora bisoprolol, zvinokosha kuziva chii allergens kuti immunotherapy kana atakatora kuti ganda miedzo aigona chirwise kukura zvikuru systemic neutachiona kana anaphylaxis. Kunogona kukonzera anaphylactic kuvhunduka uye mawa kushandisa bisoprolol uye iodinated musiyano nevasori kuti intravenous yaitonga.

Diuretics, sympatholytic zvinodhaka nezvimwe antihypertensive, bisoprolol rinoshandiswa pachiimbwa, kunogona kukonzera richikwidibira pamusoro BP.

Tetracycline antidepressants, antipsychotics, sedatives uye hypnotics zvinodhaka inoodza mwoyo musimboti tsinga. Mugumisiro jekiseni kana zvimwe zvinodhaka akafanana hypoglycemic kuti mukanwa yaitonga panguva kurapwa pamwe medicament "Konkor VaK" zvowedzera. Symptomatology dzichiri yomuropa (tachycardia zvikurukuru) inogona woutsinye kana Masked.

Chii kunotsvaka?

Vanhu "Concor VaK" riri basa application ndiyo inadmissible pachavo kuti vasavhiringidza kurapa kana kushandura zvavakabvumirana chipimo chemushonga pasina kutanga kurangana nachiremba wako. Muzviitiko zvakadaro zvinokwanisika kuwedzera mwoyo basa. Izvi ndezvechokwadi kunyanya varwere coronary tsinga chirwere. Kana zvinovawo zvakakodzera kuti zvokugumisa kurapwa mishonga "Concor VaK", mugadziri wezvinhu anokurudzira kuti imi muite izvi, zvishoma nezvishoma achidzikisa chipimo chemushonga.

At kuputa varwere kubudirira Beta-blockers kuvatumwa vasingakandi kuputa.

Vaya vanopfeka kuonana lenses, unofanira kuyeuka kuti Beta-blockers zvinogona kukonzera kuderera pagadzirwe kubvaruka mvura.

Kana murwere nezvechinhu chimwe chikonzero zvokuwedzera kuvhiyiwa, kugamuchira "Concor VaK" vanofanira kurega kutora zvose kwete asingasviki 48 maawa pamberi zvayo rufimbi. Kana Kuvhiya kunodiwa nokukurumidza, uye murwere atogamuchira mumwe Beta-blocker, nokuti mukuru yokutindivadza zvakafanira kusarudza mushonga shoma kunaka inotropic simba.

In mhedziso ndinoda kutaura kuti chero aifanira mishonga "Concor VaK" kuverengwa, wongororo pamatunhu kunyatsoshanda kudivi kuvarwere uye vashandi utano, chisarudzo pamusoro kugadzwa zita mumwe nomumwe munhu rinoreva "Concor VaK 'uye kwete mumwe Beta blocker, zvaifanira kuva chete kuti kupinda chiremba.