Analogue pamusoro Plavix.

Mumwe aibatanidza antiplatelet mishonga iri chinodhaka, "Plavix". Nhasi chiri kakawanda inoshandiswa mukurapa, zvakadai somunhu analogue pamusoro Plavix zilt. The mushonga sezvamunoita inosanganisira clopidogrel uye acetylsalicylic acid. The chikuru zviito mishonga kugadzirira inoendeswa chinovhiringidza pakati ADP-Kanotokonya mhosva aggregation masero eropa (zvikurukuru maplatelet). A runoratidza kugadzirira zviri kusingarapiki nokusungwa ADP-receptors, iyo inosvitsa mudanga kukanganisa aggregation. Somugumisiro Kanotokonya basa anodzorerwa chete parufu rekare uye kwetunhu maplatelet matsva. Ndizvo marongerwo uye mashandiro chiito pamusoro analogue pakati Plavix - zilta.

Clopidogrel (Plavix analogue) rinoshandiswa nenzira chipimo chemushonga pamusoro 75 milligrams. Pazuva achitora zvinodhaka wokutanga wakaratidza chinokosha attenuation kuti platelet aggregation basa. Pamusoro Zvakazoitwa kushandisa zvinodhaka maturo inowedzerawo. Hour Cycle mishonga gadziriro ndiko avhareji matatu mazuva manomwe. Pashure discontinuation zvinodhaka maturo zvinonzi kuchengetwa (kwete zvakazara achiudza kusvikira akawanda platelet nziyo) mumwe nguva mashanu mazuva manomwe.

Salicylic asidhi hunokonzera chinovhiringidza kuti platelet aggregation nokuda kusingarapiki chinovhiringidza pamusoro cyclooxygenase (Cox-1). Somugumisiro, akaderedza thromboxane usage uye attenuated vasoconstriction. Sezvo kuna clopidogrel vakafurira kushanda anodzokororwa pamusoro poupenyu masero eropa (maplatelet).

Sei kushandisa analogue pamusoro Plavix uye mushonga pachayo? Kushandiswa kupfuura zvinowanzovapo mubatanidzwa antiplatelet ARV unoruramiswa pangozi yokuva pakati vascular thrombosis chero nzvimbo pamberi atherosclerotic maronda.

Pane mumwe akakurumbira zvikuru analogue pamusoro Plavix - listab. Zvisinei, iye, kufanana nevamwe vakawanda (klopilet, lopirel, plargil, detromb, plogrel, Trocken, kardutol), haasi zvinowanzoshandiswa ano okurapa.

Plavix kana zilt?

vanachiremba Most akazendamira akananga pakushandisa Plavix, sezvo kushanda kwayo kwave akaratidza nemiedzo randomized. Umbowo zvinodhaka angosimuka shure muna 2007 uye mumakore mashanu apfuura, zvinoshingaira kushandiswa chete akasimbisa musoro "yakanakisisa chigadzirwa". Kana zilta, ayo kushanda, sezvataurwa ne vanachiremba pachavo, yakati kudzika kupfuura akataura, saka zvichienzaniswa kwayo ishamwari nekuda yakambomira yokurapwa haagoni. Zvikurukuru, masayendisiti anodavira kuti pasi kunyatsoshanda okupedzisira imhaka Kusakwana muzvigadzirwa basa mukugadzira chezvinodhaka. Biophysics chete cherechedza vamwe kusawirirana mune samolecular chivako pakati Plavix uye ayo analogue.

Kana mutengo, izvozvo yekudyidzana anorasikirwa Plavix ziltu. Saka, mutengo rokutanga katatu kukosha wechipiri. Muzviitiko zvizhinji, mari zvinodhaka kunotungamirira kudiwa kushandisa va neudhadha dzomuzana. On yevimbiso vanachiremba kumakiriniki ano, kana iwe usingagoni kutenga Plavix zvinodhura havafaniri kutenga isingadhuri analogue rayo - zilt. Chose asiye kubvuma zvinodhaka hakuna inokurudzirwa.

Zvazvakadaro mushonga se "Ko Plavix," ipapo ndiko kuzivikanwa yakawedzerwa chipimo chemushonga imwe chikamu zvinoriumba (100 uye 75 MG pamusoro salicylic acid, uye clopidogrel, ukuwo).

Zvinosuruvarisa kuti musi kugadzira michina "Plavix" medicament, uyewo yaro constituent zvinoriumba vari kudhura chaizvo, zvinoita kuti kudhura kurapwa. Kubatsira achitsigira varwere shoroma kuuya analogues zviri mufashoni mishonga yakanaka kwazvo.