Bile basa iri kugaya

Bile - chinhu chakavanzika chiropa hepatocyte masero. It rinoungana mune diki bile ducts, uye ipapo anopinda vanhuwo mutsinga dzinofamba nemukaka uye kuburikidza nayo - the gallbladder 12 uye duodenum. Mabasa mutumbi bile zvakakosha. Imwe yacho huru mashandiro - zviri munyaya dzinotsanagura kugaya.

Apo bile inochengeterwa?

Nduru dundira iri chekuchengeta tangi nokuda bile. Munguva vanoshingaira chokutambudzika kugaya, kana kubva mudumbu kupinda duodenum 12 kunopinda zvishoma ozeyewa zvokudya, pane ari dzinounzwa ayo kunonyanyisa chitsama. The chikuru mashandiro anoita bile kwevanhu - mugove kugaya uye kweiyi secretory basa uye motility pamusoro ura duku, iyo dzinovimbisa kubudiswa chikafu bolus.

Bile, iyo anosunungurwa mugomba zvomudumbu turakiti iri gallbladder, akadana vakura uye akasunungurwa zvakananga chiropa - vaduku, kana chiropa.

Process uye biliary excretion kuti bile

Muitiro generating chakavanzika hepatocytes (cholepoiesis) kunoitika dzose. Vakaita dzakatevedzana rokuchenesa ropa zvinhu zviri bile capillaries. Uyezve, nokuda reabsorption nemvura chicherwa munyu inoitika wokupedzisira paumbwe Kuronga secretory zvinwiwa. Izvi zviri kuitwa bile ducts uye gallbladder. Part of bile runoyerera zvakananga kupinda ura, kunonzi hepatic kana vaduku. Asi uremu yayo huru iri vaunganidza nduru dundira, izvo chinokambaira bile ducts. Gallbladder bile rinoungana, zvinova gobvu uye kuramba. Zviri zvasviba kupfuura chiropa.

Masikati, chiropa masero nedzevakuru kubereka anenge maviri litres ose secretions. Kutsanya iye asiri achipinda ura. Postprandial biliary excretion kunoitika (holekinez) muna 12-duodenum. Pane bile mabasa somunhu zvomudumbu, uyewo bacteriostatic uye pamutemo. E. Process pachahwo regulator kuti bile kugadzirwa uye biliary excretion.

Saka, zvikuru bile acids akabudiswa mugomba portal riparadzirwe (portal tsinga), kuti wakakwidzwa dzavo wevasungwa ari bile nziyo uye, naizvozvovo, muduku synthesized ne hepatocytes. Mashandiro anoita bile uye pancreatic muto zvinokosha kugaya.

ari Zvinoumba bile

The chikuru chezvinonhuwira bile asidhi vari cholic. Most (67%) - munhu cholic asidhi uye chenodeoxycholic. The yasara asidhi - chesekondari, kureva, nomukaka idzi acids zviviri: deoxycholic, alloholievaya, lithocholic uye ursodeoxycholic ...

Vose bile acids zvinowanikwa pakavanda ichi muchimiro yeimwe vane taurine uye glycine. Zviri yakawanda yavaibvisa uye potassium ions zvinopa alkaline kuita bile.

Mukuwedzera, Zvinoumba bile zvinosanganisira zvimwe Organic zvinhu :

• Phospholipids.
• Protein yeimwe, kureva immunoglobulins A uye M.
• Bilirubin uye biliverdin (bile pigments).
• Remafuta akawandisa.
• Mucin.
• Lecithin.

Uyewo, ions vane dzimwe simbi (zingi, mhangura, kutungamirira, magnesium, indium, mekuri), mavhitaminzi A, B, C.

Vose pamusoro zvinoriumba inhengo uye chiropa, gallbladder uye bile, asi anenge 5 nguva kuvatumwa avo wevasungwa rokutanga pane yechipiri.

bile basa

Ivo kunyanya chokuita basa nemudumbu. bile basa iri kugaya chokuita akatevedzana enzymatic siyana.

1. Under nawo pane emulsification kwemafuta, nokudaro kufambisa Absorção de Água yavo.
2. It neutralizes zvinokonzerwa pepsin (gastric muto mukuru zvinoriumba), rinogona kuparadza pancreatic makemikari.
3. Zvaanopa simba ari motility yacho ura duku.
4. Kunomutsa kugadzirwa madzihwa.
5. Gastrointenstialnyh zvaanopa simba kugadzirwa hormone, secretin uye cholecystokinin, izvo anobudiswa neZvapupu masero ari ura duku uye zvinobatsira kuti mutemo secretion pakati rwatata.
6. Rinodzivirira adhesion (adhesion) mabhakitiriya uye proteinaceous zvinoriumba.
7. It ane akambozvishandisa kuuraya utachiona zvainoita ura rinobatanidzwa paumbwe mutsvina yadzo.

Saka, mashandiro ari bile ari kugaya hunokosha. Zviri nokuda bile zvomudumbu muitiro, atanga mudumbu, anopfuurira uye inoguma iri ura zvakachengeteka.

Bile ukoshi kuti muviri womunhu

Saka, takaona kuti huru mashandiro bile chokuita zvomudumbu muitiro. Chii chinoitika kana, nokuti vamwe chikonzero, kuchinja Zvinoumba bile kana iye asingadi kupinda zvomudumbu turakiti? Nekushaya kana kusamuda kunotungamirira zvakakomba pathologies:

• Cholelithiasis.
• Steatorrhea.
• Gastroesophageal reflux chirwere (Gerd), uye vamwe.

cholelithiasis

zvokurwara Izvi zvinogona kuitika nokuda asina kudzikama Zvinoumba bile. Izvi zvinonzi lithogenic bile. ehupfumi akadaro vangadzidza panguva dzose zvikanganiso zviri zvokudya, zvinoti kana zvokudya hunodzorwa mafuta mhuka. chiropa bile mabasa kungakanganiswa somugumisiro zvirwere kwemakemikari anobudiswa. Uyezve, lithogenic ehupfumi ari hepatic secretion vangadzidza somugumisiro kusagadzikana lipid muviri, izvo kazhinji pamwe kuwedzera uremu muviri. Chikonzero kuchinja kubva bile sezvamunoita kunogonawo kuva chirwere uye hunokachidza kukuvara chiropa kana insufficiently kushingaira mararamiro (nokusarovedza muviri).

stearrhea

Sezvataurwa pamusoro apa, mashandiro chokuita bile emulsification kwemafuta. Kana kuti zvimwe chikonzero iri bile hunoguma iyerere kupinda ura duku tibatsirwe mafuta zvikasaitika, uye ivo muchamira kunze mutsvina yadzo. Ndizvowo zvinogona kuitika chete Kwevamwe iri hepatic secretion kuti bile acids (shanduko ayo sezvamunoita). Panyaya iyi, iyo mutsvina yadzo jena kana bvudzi uye zara mafuta kusachinja-chinja. zvokurwara iyi inonzi steatorrhea. With chirwere ichi, muviri hauna kukwana zvinokosha mafuta, mafuta acids uye mamwe mavhitaminzi. Nokuda steatorrhea vanotambura yakaderera bowel, t. To. Havasiyiwi kujairana chyme kwakadaro.

Kuongorora bile?

Kuti kuongorora marongerwo uye mashandiro bile, akashandisa nzira dzakawanda fractional duodenal intubation. nzira iyi ine matanho shanu:

1. Basal secretion pakati bile - ndiyo hurumende ichiisa nevakariri bile mutsinga dzinofamba nemukaka 12 secretion uye duodenal urikanwi. Rinotora maminitsi 15.
2. Secretory danho Kumbomira kana namahwindo sphincter kuti oddi. Ya kuyaruka uyu maminitsi 3.
3. Danho Kuparadzana of residual mugove A. bile rinovapo anenge 5 maminitsi.
4. Danho kuparadzana gallbladder bile migove B. Iyi nguva rinovapo kwemaminitsi anenge 30.
5. Voga kuti hepatic bile - mugove S. danho iri rinovapo anenge maminitsi 20.

Saka, mumwe mugove 3 of bile. Vose akasiyana mune sezvamunoita. Zvikuru kuramba bile vesical - mugove B. Rine mukuru yakawanda mafuta acids, bilirubin, uye dzimwe bile zvinoriumba.

Nzira iyi inobvumira kuti kudzidza yokuziva ehupfumi ose bile mumuviri, akafanana kwayo, kuwanda nduru dundira, mamiriro ezvinhu ari biliary turakiti , uye kuona localization ari pathological muitiro.