Hypogonadism nevanhu: Zviratidzo neMarapirwo

Full nokushanda muviri womunhu haugoni kufungwa pasina zvakakodzera kushanda bonde omumuviri, kugadzirwa mahormone. Chero kukundikana munyika ino kunotoreva kuti kwaita somatic zvirwere. Dyslipidemia, atherosclerosis, kufutisa, uropi ischemia - ichi hachisi mazita yose zvichibvira yematambudziko. In zvokurapa mabhuku akawana tsanangudzo dzakawanda kutyora kwakadaro. Somuenzaniso, testicular androgen kukanganisika kana insufficiency. Zvisinei, pakati pavo, zvikuru akavimbika uye chinonyanya yakarurama vaiona rokuti "hypogonadism" nevanhu. Kuti ichi chinoreva, nokuti chipi chikonzero unovapo kana chinogona kupera - mibvunzo aya akapa mhinduro hwakadzama nhasi nyaya.

tsanangudzo pfupi pamusoro chirwere

Hypogonadism - chirwere dzinoratidzwa dzichipfekeka kushaikwa bonde mumasero. The vamiririri akasimba pabonde dzinoturwa kuruboshwe uye zvakarurama jende. Nature akapa zvikuru aiwanzopiwa wokushanda izvozvo nhamba yavo. Testicular zvinyama aikanganiswa dzezvakatipoteredza ngozi siyana. Kana kurasikirwa dzichipfekeka nemano muviri anofanira Reserve ane mhando. Rokuzvivandudza rakaita kuti irambe mano testes iwayo mwero.

chinangwa chavo chikuru - kuti kubereka. Kushaikwa kugona kubudisa urume kuwana muviri munhurume dzokubereka nezvaanogona. Zvigadziriswe dzakadaro kutyorwa vakaisa pane kutanga kwekupwanyiwa dzokubereka kutenderera. Naizvozvo, kushaya mbereko, kukura iyi background, zvinonzi vaiona ngozi chaizvo. Dzosai basa kanganisika masero testicular zvinyama kwakaoma zvisingaiti.

Hypogonadism nevanhu dzinoratidzwa anotevera zvinhu:

• zvishoma nezvishoma zvinoderedza padanho bonde mahormone;
• kuderera kwemitambo Qualitative uye quantitative maitiro urume;
• hypoplasia of sikarudzi;
• hormone nepfungwa yose muviri.

Maererano nenhamba, kuti urwere pakati hypogonadism nevanhu kunoitika muna 1% vemo nyika. Zvisinei, mashoko aya ndiwo dikidiki, sezvo vari kufungwa chete vakanyorwa zviitiko zvokurwara. Treatment hako kunze pasi pokudzora ane endocrinologist uye andrologist. The anowanzodanwa kushandiswa kemikari mishonga. Kana basa kusvikira ineffectiveness mapurasitiki kuvhiyiwa uye prosthetics nhengo dzokubereka nadzo.

The kukonzera chirwere

Kukura pathological muitiro kunoitika pamusana kuderedza anogadzirwa mahormone kana nyonganyonga biosynthesis. By etiological zvikonzero chirwere zvinosanganisira:

• vachiberekwa malformations anokonzerwa nokuchinja testicular marongerwo uye / kana seminiferous tubules;
• simba pamusoro muviri zvinokachidza vanaamai ramangwana (doro, chikakananda, zvinodhaka);
• kumbotambudzika nemwaranzi kana mishonga;
• kushandiswa kwenguva refu kuti hormone, antibacterial zvinodhaka;
• zvirwere zvinotapuriranwa mavambo (orchitis pashure gwirikwiti, mumps, vesicles);
• varicose mutsinga of manhu;
• pekugara kunzvimbo dzine ezvinhu ipa zvakatipoteredza.

The zvinokonzera hypogonadism nevanhu kuti Maumbirwe pathological muitiro. Mumwe nomumwe wavo kunoratidzwa imwe ndima.

mhando kutyorwa

Zvichienderana chiri kukonzera panowanikwa kukundikana gonads rakakamurwa chikuru, chesekondari, uye anonzi zera. Sei zvakasiyana? The chikuru chimiro maperembudzi zvimwe inonzi testicular zvokurwara. Panyaya iyi, pakanga pakaputsika testes kushanda zvichiitika pasi pokudzora kwokunze kunaka zvinhu. Secondary hypogonadism nevanhu Rinobatanidzwa ne abnormalities vari anorimwa "pituitary-hypothalamus". ino zvinoberekwa mahormone anokonzera kushanda testes. Age musiyano wezvinyorwa chirwere anoonekwa kuti sechibereko munhurume kubereka. Its zvinokonzera, vanachiremba havagoni kutsanangura nhasi.

Zvinotevera kupatsanura anobva nguva muupenyu kwaiva chirwere. Embryonic chimiro kunoratidzwa nezve pathological kwacho munguva uterine kukura. Prepubertal chirwere asati pakuyaruka (makore anenge 14). Postpubertatnom musimboti maperembudzi kunoitika pashure okuguma kukura kwezvinhu yechipiri dzepabonde zvatariswa.

Akapiwa uwandu androgens anogadzirwa, kusiyanisa zvinotevera akasiyana chirwere:

1. Hypergonadotrophic hypogonadism. Varume, chimiro ichi chirwere kunooneka pacharo muchimiro nokuparadzwa testicular testicular tishu. Zvinonzi pamwe zvakawedzera kugadzirwa pituitary mahormone. Panguva iyoyowo zviratidzo zviri testosterone yekudyidzana ipfupi.
2. Hypogonadotropic hypogonadism. It dzinoratidzwa yadzikira kwetunhu gonadotrophins. Izvi zvinoderedza uwandu testosterone anobudiswa.
3. Normogonadotropic hypogonadism. Varume, chimiro ichi pathological muitiro kunotungamirira nokuvhiringidzirwa pakati manhu, asi kugadzirwa pituitary mahormone romuzvarirwo. The chirwere runowanzotaurwa nezvarwo kufutisa.

Zvichienderana etiology itsika kusiyanisa vachiberekwa, ndakawana uye idiopathic siyana. Mukupera nyaya, chikuru chinokonzera chirwere havasati.

chikuru hypogonadism

The chirwere kunogona vawana uye vachiberekwa. Kakawanda, zvokurwara rinowanikwa mune utero. Mukomana akaberekwa aine mboro diki uye chinhu underdeveloped scrotum. Sezvo kuchinja ari kurapwa mufananidzo chirwere mutates. In kuyaruka vakomana vane chirwere dzakaonekwa kufuta, gynecomastia kutanga anokuzviratidza uye vakaderera bvudzi muviri.

Vakatodzidza chikuru hypogonadism nevanhu ikabuda iri kuzvimba seminal mumasero pasi zvinotevera zvirwere:

• orchitis;
• vesicles;
• epididymitis;
• mumps;
• Chicken pox.

Ichi chimiro chirwere ichaongororwa kuti rakajairika. It kunoitika muna rimwe kubva shanu varume kare chirwere mbereko.

Secondary hypogonadism

Secondary hypogonadism kungava vachiberekwa kana vawana. Kana hosha chokutanga pashure pokumuka kukodzera secretion pakati pituitary uye hypothalamic mahormone. It kunowanzoguma nemagene zvirwere:

• Prader chirwere - Willie;
• Maddock urwere;
• Pasqualini syndrome.

The vawana chimiro chirwere inowanzopiwa kunokonzerwa kuzvimba meninges. Pakati pavo vane yomumuzongoza, arachnoiditis uye encephalitis.

Zviratidzo zviri chirwere muvana vaduku

The kunotoda Mufananidzo pathological muitiro dzinongoita pakutsvaga murwere zera. kukura kwayo kubva pazera iri kazhinji pamwe anotevera zviratidzo:

• Nyonganyonga pakuyaruka;
• evnuhoidizma pakuonekwa zviratidzo (zvakanyanyisa yakakwirira kukura, mapendekete diki, maoko nemakumbo refu);
• kusavapo wrinkles vari scrotum;
• duku kukura yemukomana;
• gynecomastia.

In pamberi mumwe kana kupfuura zviratidzo dziri pamusoro hwobva watarisa Profile nyanzvi.

Zviratidzo zviri zvirwere kuyaruka

Kukura hosha iri kuyaruka kunoratidzwa chete zviratidzo, kuti prepubertal. Clinical mufananidzo kungaita ungaderedza libido uye kufuta. Kuona chiremba inowanzopiwa dzakaonekwa hypoadrenalism uye thyroid. Nechokunze, varwere vechiduku zvakajeka akaratidza underdevelopment pamusoro tsandanyama hurongwa.

Zviratidzo zviri chirwere nedzevakuru

Hypogonadism mune varume vakuru kupfuura makore 30 iri shoma raidudzwa. The chirwere achabatsirwa nechitarisiko pazvirugu akawanda mafuta pamusoro muviri. Skin pamusoro nguva chisanyanya aimbova elasticity uye yaoma. Rinooneka kuneta, mupfungwa lability, tsika mwoyo. Zvinosuruvarisa muchipatara kubatwa varume asina mhosva. Kazhinji kana totaura mwana kana kusagadzikana erectile chaitika.

Izvi kushaya pfungwa pachavo utano hwavo vanogona kuguma zvakakomba. The pathological muitiro anotanga chikasanyenga chete pamusoro dzokubereka nadzo, asi zvishoma nezvishoma kutamira dzimwe nhengo uye munyama. Kusavapo nomazvo hanya zvinogona kuremadza.

nzira nechirwere

Musatya nechirwere vakamhanyira hypogonadism nevanhu. Kuti mamiriro ichi zvinoreva kuudza chiremba pakutanga kubvunza. Pashure nechitarisiko chirwere zviratidzo hwobva kutaura anokwanisa mukoti. Pasinei kumbonyanya rakajeka kunotoda mufananidzo, yekusimbisa chirwere vanofanira chaidzo kunotoda wakatarwa. Chinosanganisira zvinotevera mabasa:

• panyama ongororo;
• Pelvic Ultrasound;
• karyotype;
• urinalysis;
• urume;
• bvunzo ropa nokuti mahormone.

The Ongororo iri basa mumwe murwere nomumwe. Naizvozvo, mazita kunotoda kurapwa zviitiko zvingasiyana zvishoma. chiremba inosimbisa kana anoramba rokutanga zvokuongorora pahwaro ari ndawana zvabuda, ibasa kurapa.

Features kurapwa

Selection imwe nzira yokurapa zviri chiremba uye akatsunga kufungisisa zvinokonzera chirwere. Mabatirwo hypogonadism nevanhu kazhinji ane zvinangwa dzakawanda: chinorwisa zvirwere zvikuru, kudzivirira mwana, kudzivirira panowanikwa namamota ari testicular tishu.

Vachiberekwa uye prepubertal siyana zvokurwara vari kunowanzoguma mbereko. Kubvisa dambudziko iri hazvibviri. Kana endocrinocytes anochengeterwa testes, Zvinokurudzirwa dzishande mishonga. Vana ushandiswe hormone zvinodhaka, uye vakuru - vanofanira androgens. Pasina kwemakemikari anobudiswa mahormone vanofanira kunwa hwose.

In yechipiri chimiro pathological muitiro gonadotropic ushandiswe zvinodhaka duku chipimo chemushonga. Kana zvakakodzera, vari pamwe chete testosterone. A basa pakurapa chirwere ndezvevanhu jimunasitikisi uye kugamuchira vhitamini zvivako.

zvinodhaka All vari ushandiswe nomumwe zvichienderana utano chinzvimbo uye zera murwere. kushandiswa kuzvitsinhanisa mishonga pamwe hormone yomuchipatara haina varumbidzwa dzimwe nguva. Somuenzaniso, mune kenza maronda kweprostate. Chirwere zvemapapu chirwere, kusvuta, havachanyatsogoni mafuta muviri uye kufema kurwiswa - vane hama contraindications. Mumamiriro ezvinhu aya, chisarudzo pamusoro kubvuma testosterone zvinodhaka yatorwa nomumwe.

kuvhiya kupindira

Kana hypogonadism nevanhu kunokonzerwa vakaremara kukura pabonde nhengo, achiratidza kuvhiyiwa. Nhasi, zvakasiyana-siyana zvaramba kuti kupindira rinoshandiswa kubvisa chirwere. Somuenzaniso, pamwe hypoplasia iri mboro inoshandiswa phalloplasty, panyaya undescended testis rinoitwa relegation. muchibereko chakaita zvokugadzirwa testis kuitwa kubvisa kuremara zvizorwa. Chero remapazi izvi rinoitwa kushandisa microsurgical nzira.

The for kupora

Primary hypogonadism, kunyanya vachiberekwa, zvinogona yapera kugadziriswa. Zviri pamusoro kudzorera anatomical uye dzichipfekeka nemano yemukomana. Zvisinei, mushonga ano kuti normalize ejaculation kuita. The chete kuita kuti vawanezve kubereka - IVF dzisingaoneki kubudikidza fenzi. Saka vnutriyaichkovy spermatogenesis anofanira kuchengetedzwa.

Chimwe kushurudzira anotarisira varwere nechirwere hypogonadism yechipiri. Varume, pakurapa chirwere kakawanda kupa migumisiro yakanaka. Naizvozvo, vanachiremba kazhinji havagoni chidzosai pamuviri ushande.

matanho

Dzakananga kudzivirira chirwere ichi haina dzakabudirira. Pakati mukuru vanorumbidza pavadzidzisi vanodana zvinotevera:

• nokukurumidza kurapwa chero chirwere;
• kudya zvinovaka muviri, kushaya tsika dzakaipa, kurovedza muviri;
• richipfuura rokuongorora panguva "munhurume" vanachiremba kuzvidzivirira nechiyero kamwe pagore.

Mazano aya zvinosuwisa, hakusi nguva zvinogoneka kudzivisa hypogonadism nevanhu. Panguva yokutanga kuonekwa hwobva kutsvaka rubatsiro kubva mazvikokota. Kwokutanga chiremba taurira kurapwa, nokukurumidza vachatitaka apore.