Loperamide hydrochloride. Loperamide hydrochloride - nokurairirwa Chinyorwa

Chii chinodhaka "Loperamide hydrochloride '? A mhinduro nzwisisika kuti mubvunzo uyu anogona kuwanikwa zvinhu inopiwa nyaya. Uyezve, isu vachakuudza zvizere sei kutora mishonga, kana uye chii chipimo chemushonga.

Vhuṱanzi

The medicament "Loperamide hydrochloride" chinhu symptomatic chinodhaka iro rinoshandiswa kurapa chakasimba uye chisingaperi manyoka. mushonga Izvi atengeswa pasina mushonga uye vakatengesa anenge ose chemishonga mukana wekuti mutengo.

Pharmacological migumisiro

Kugadzirira "Loperamide hydrochloride" mirayiridzo iri nested mu atorwa, kunoderedza motility uye Matauriro anotsvedzerera tsandanyama pamusoro ura uye kuchititadzisa peristalsis muviri, kuwedzera zvikuru kupfuura nemunyika nguva yaro zviri. Nokudaro, akauya medicament rine antidiarrhoeal kushanda. Zvinofanira kucherechedzwa kuti zvinodhaka "Loperamide hydrochloride" anotanga kuita nokukurumidza chaizvo. Pamusoro negashiro zvinodhaka ichi mukati kuchirapa kushanda rinovapo kwemaawa anenge 4-6.

Pharmacokinetics

mumwe medicament kwakadaro wefodya ari ura rakanyatsojeka murombo (anenge 40%). Nokuda mukuru kufanana receptors ari intestinal masvingo, uyewo mukuru mwero biotransformation panguva ndima yokutanga kuburikidza chiropa yeplasma kwevari unmodified pakuderedza mushure mekugamuchira zvinoreva 2 MG (1 Kamudzira) idukusa 2 kumar / Rine mamiririta. The kunonyanyisa wevasungwa yezviri fuma pashure kushandiswa inotoda zvasvika pashure maawa anenge 2,5, uye mushure capsules - pashure pemaawa 5. Unosungira kuti mapuroteni eplasma kunoitika muna 97%. mushonga uyu rinoita muna chiropa uye rinobva muchidimbu kubva weti, sezvo verlauf pamwe bile, uyewo pamwe mutsvina yadzo.

Release chimiro mishonga kwayo sezvamunoita

Kugadzirira "Loperamide hydrochloride," kushandiswa inorondedzerwa hereinafter, iri kutengeswa muchimiro:

• Fuma upfu kuti mhinduro.
• 2 MG pamahwendefa, inoiswa mumba atorwa zvidimbu 50, 30, 20 kana 10.
• 2 MG capsules akaisa mukati pasuru 30, 20 kana 10 zvidimbu.
• Gelatin zvakaoma capsules tsvuku, izvo ane chena upfu pamwe yezviri zvinoriumba - loperamide hydrochloride. Mumwe Kamudzira rine 2 MG kuti basa fuma. Kunze anomirirwa medicament rine wayo sezvamunoita uye ebetsero zvinhu: talc, chibage starch, lactose, magnesium stearate uye colloidal silica. Gelatin capsules vari kutengeswa muna atorwa zvidimbu 20 kana 10.

Ndokupi zvine basa kuchatibatsira loperamide hydrochloride? Kushandiswa fuma iyi pharmacology uye anobvumira mishonga yakadai "Imodium" uye "Diara". Zvisinei, kubva muzana yayo iri Formulations izvi iduku zvikuru pane zviri munhoroondo medicament.

Drug "Loperamide hydrochloride": chii chinorehwa?

Maererano mirayiridzo, mushonga kunodiwa kutora zvinotevera nyaya:

• Kuti normalize Chair pa ileostomy.
• Kana metabolic zvirwere uye intestinal Absorção de Água, izvo zvinokonzerwa kamwe uye achinje zvikuru muna zvokudya kana senguva Zvinoumba zvekudya (Somuenzaniso, panguva kudya, rwendo).
• Webetsero mushonga mu noutachiona manyoka.
• Sezvo symptomatic pakurapa chakasimba kana chirwere manyoka (sema, mwaranzi, mushonga kana mabviro mupfungwa).

Contraindications pakushandisa mishonga

Mune zvimwe zviitiko, haugoni kushandisa zvinodhaka "loperamide" (Mahwendefa)? Yakapiwa mishonga rinoti hazvina pachii:

• intestinal mhingaidzo;
• manyoka, izvo kwamuka nokuda nemanyoka, chenjera pseudomembranous enterocolitis kana zvimwe zvirwere zviri zvomudumbu turakiti;
• diverticulosis;
• chenjera maronda colitis;
• hypersensitivity.

Zvinofanira kucherechedzwa kuti zvinodhaka izvi antidiarrheal vana vanofanira kupiwa chete-gore 4. Uyewo, maererano nemirayiridzo, rinoreva "loperamide" iri contraindicated ari trimester pamuviri rokutanga uye munguva lactation. With hanya zvikuru mushonga wacho nachiremba chiropa kukundikana.

The medicament "Loperamide hydrochloride": mirayiridzo kushandiswa

Mahwendefa uye capsules zvinodhaka kutorwa nomuromo pasina dög. The chipimo chemushonga zvinodhaka kunoenderana makore murwere uye chirwere kukuvadza.

In chenjera manyoka nedzevakuru sezvo wokutanga dose raitongwa 4 MG zvinodhaka uye ipapo - ne 2 MG pashure mumwe defecation (kana cheya achiri mvura).

In chisingaperi manyoka yokutanga dose ndiyo 2 MG. Kutsigira kurapa nokuti vakuru vanofanira zvakavakwa kuitira kuti murwere pachituru maitikiro yaiva 1 kana 2 nguva pazuva. The kunonyanyisa dose daily - 16 MG.

The kuchirapa mugumisiro kutora mushonga wakadaro anova mumaawa 48. Kana, zvisinei, nokuti mazuva 2-4, tichishandisa kusvika 16 MG zvinodhaka zuva nezuva, haugoni kubudirira zvinodiwa mugumisiro, nguva dzose unofanira kubvunza chiremba, uyo akavanunura hwokufungazve chirwere. Kushandisa zvinodhaka zvinogona kudzokororwa, asi kana dzakananga chete kurapwa kana kudya zvinenge zvataurwa hakurevi normalize chair.

Kana vana, kwakadaro mushonga rinofanira kushandiswa makore 4 chete okuberekwa. The dose zvakare novimba makore murwere uye kukomba kwechirwere chacho.

Vacheche kubvira 4 kusvika 7 apfuura, mushonga unofanira kupiwa 3-4 kanomwe pazuva kusvika 1 MG. Duration yokurapa ndiyo 3 days. Vana 7 kusvika 12 makore raitongwa nguva mana pazuva 1 piritsi nokuda 5 mazuva. In chenjera manyoka kwokutanga chipimo chemushonga vana vanofanira kuva 1 Kamudzira. Kufadza daily dose vana - 8 MG.

Kana mwana manyoka aona pashure chiito chimwe nechimwe defecation munguva refu, nguva dzose inofanira kupiwa 1 Kamudzira, asi kwete kupfuura 6 MG pa 20 kg asi kurema muviri pazuva. Kana mwana asingadi kuenda maawa anopfuura 12 kusvika chimbuzi, uye pashure normalization kuti chetsoka kugamuchirwa akapa nokuda mushonga vari zano kurega.

zvinodhaka ovhadhozi

Kana ovhadhozi pamwe zvinodhaka izvi murwere zvinotevera zvarakasiya zvinogona kuonekwa:

• kuvhiringidzika Kufambisa nemafambiro;
• constriction of vadzidzi;
• vadhakwa;
• hope;
• yakawedzera skeletal tsandanyama inzwi;
• bowel mhingaidzo;
• kufema mwoyo.

Kubata vakadaro pathological inoti vanachiremba kazhinji zvinodhaka "Naloxone" rinoshandiswa mawa symptomatic kurapa.

nemishonga

Zvinofanira kucherechedzwa kuti pashure pokushandisa kugadzirira "Loperamide hydrochloride" varwere vanogona zvakasiyana nemishonga. Kakawanda zvaitika nekushandisa kwenguva yakareba zvinodhaka. Saka kumiririrwa medicament kungaita zvinotevera nemishonga:

• flatulence;
• electrolyte abnormalities;
• kurutsa;
• intestinal chinyamunhari chinorwadza;
• dzungu;
• gastralgia;
• svoto;
• hypovolemia;
• hope;
• muromo yakaoma.

In vana vaduku, mumwe mushonga kunowanzokonzera kusagadzikana mudumbu, uyewo ganda rashes. Very kashoma medicament "Loperamide hydrochloride" anogona kukonzera Urinary chengetedzo kana intestinal mhingaidzo.

Kana pashure 2 Mazuva ano mananara regai kunyangarika, uye murwere haafungi nani, nguva dzose unofanira kubvunza chiremba, uyo Utare mumwe (akafanana) chigadzirwa. Kana mushonga asingadi kubatsira, zvakanakisisa aone kuti zvirwere kuti manyoka.

zvinodhaka kwavatori

Maererano mirayiridzo, apo kushandisa kugadzirira "Loperamide hydrochloride" uye "Cholestyramine" wokutanga kunyatsoshanda anogona kudukupiswa. Kana uchida kushandisa mushonga pamwe rinoreva "Co-trimoxazole" kana "Ritonavir", unofanira kuziva kuti ayo bioavailability iri yekudyidzana ichiwedzerwa.

Zvokungwarira

Drug "Loperamide hydrochloride" zvinofanira nokungwaririra kunyanyisa mune hepatic vanotaura. Zvinonzi zvakare haana varumbidzwa kurishandisa mune izvi zvekuchipatara ezvinhu apo chinovhiringidza pamusoro intestinal peristalsis. Pasina zvakakwana kuchirapa kushanda pashure 2 Mazuva pashure kwokubatsira zvinodhaka zviri chinodiwa kunatsiridza nechirwere ari chiremba uye kubvisa chirwere Genesi manyoka.