Mirayiridzo yokushandisa, imwe analoginen "Cefotaxime" uye wongororo

"Cefotaxime" (zvairatidza kuti kushandiswa, mitemo kuti pakuverenga ari Zvakanyanya Kunaka Panguva Yepamuviri chipimo chemushonga, uyewo zvikuru nevanhu analogues achapiwa pazasi) ndiye ano Semi-chakaita zvokugadzirwa mushonga. Zviri husingakwanisi Beta-lactamases uye rinoshanda pamusoro vose giremu-akanaka uye giremu negative tusingaoneki. Mashandiro nokukanganisika Zvakaitwa nokuda kudzvinyirira kwaniso yenhengo inongoitika pezvakaitwa kuitika muchitokisi Kamudzira pakati utachiona.

The mushonga ari kupinda mumuviri, nemaune anoparadza cruciform coupling peptidoglycan, saka zvakakodzera kuti utachiona kuti tibu- kuenderera zvakasikwa madziro. Sezvo chikazozikamwa, antibodies uye FIs zvinhu kwakavharwa nenyama kurwisa masero - izvi zvikuru nyore chipfuro.

kusunungurwa Form

The medicament "Cefotaxime" (Chinyorwa majekiseni uye aizomupa zvipo sezvo chete wedunhu zvinobvira chokuendesa yezviri fuma) ari kusvitsa kune pharmaceutical pamusika chena kana tsvuku upfu, iyo inoshanda sezvo hwaro kugadzirira mhinduro. Ndiwo anonzi jekiseni ampoules.

The yepakutanga 10 Rine mamiririta vhoriyamu ndiro akagadzirwa segirazi rinoonekera. The chaiko guru reagent aripo chete chigadzirwa chikwata kunoenderana zvinodiwa chizvaro (0.5, 1.0 kana 2.0 magiramu).

pharmacokinetic Muchiitiko

Zvinofanira pakarepo kucherechedzwa kuti kwete ose analoginen "Cefotaxime" ane chete pharmacokinetic ehupfumi sezvo chepakutanga. Zvikurukuru kana pezvatinotaura mwero Absorção de Água yenhengo kubva jekiseni site yacho Absorção de Água pakati vamiririri izvi, kutonga nezvinooneka zvakataurwa vanoita zhinji, zviri nokukurumidza zvikuru kupfuura kutanga Absorção de Água mumwechete vachiri "Duataksa" kana "Tsetaksa". "Fani" The chikonzero iri muronga pakutanga mharidzo Morekuru. Nyanzvi mhinduro dzavo kusimbisa chokwadi chokuti Indian Generic pamusoro vanoumba "inogadzira mishonga kumwedzi" muchimiro kunzwisisa cephalosporin nomukaka izvo yekudyidzana DZEMUNHU DZINODZORA kuti muviri kuti zvimwe zvinhu.

Unowanikwa kuti "Cefotaxime" (kuverengwa enshrined mumaonero mutungamiriri munhu akapiwa mushonga, kutsakatisa ndingangokuvara kuenda pamberi ropa) akava hwakanyatsorwisa yakakwirira azvipire tichisunga kuti mapuroteni eplasma, apo ya microbicidal maturo kunosiyana-siyana mukati maawa 11-12. Kuva kutanga kuchinja mumiririri iri zvakaenzana richiparadzirwa mumuviri, kusanganisira mapfupa (kunonyanyisa pfungwa iri vakacherechedzawo muna myocardium uye nenduru dundira).

The chikuru wemafuta chiri anokunda placental mechidziro anova chinokosha pamusoro pericardium uye cerebrospinal mvura. Paavhareji hafu-upenyu intravenous donhwe aizomupa hakuiti pfuura awa rimwe chete intramuscular majekiseni - maminitsi zana-masere. Chero kungoramba kuunganidza zvinhu haina segwapa - chikamu zvakamisa hurongwa pamwe inenge yabudiswa muna bile uye mumwe (anenge 90%) - weti. Mukupera nyaya, nhamba vanoshingaira metabolites achingopiwa 20-30% of raitongwa dose, i.e. vanenge 70% of mhinduro kusiya muviri usina kuwana STRUCTURAL okunatsiridza.

zvairatidza kuti

nevasori izvi zvakanaka yakasimbiswa somunhu blocker nezvirwere uye anogumbura urongwa kumhanya tupukanana tusingaoneki, kunyanya nehanya cefotaxime. Uye uchapupu izvi zvidzidzo kurapwa kwete chete - mhedziso zvakafanana kunogona kuitwa pashure nokuverenga nhoroondo dzakawanda zvakanaka re pamusoro Website, musoro uri anobudirira zvinodhaka kurwisa utachiona. Front pharmacological zviito mushonga iri zvakakwana rakafara, asi kakawanda "riri kuona" vanowira chirwere kana chakasimba renal zvinetso kuitika uye Urinary turakiti, uyewo repamusoro kufema chirwere.

Ndinofanira kutaura kuti, kunyange kana Mhedziso nezvezvisikwa murwiyo ane analoginen "Cefotaxime", kana "Tsefasin" kana "Tsetaks" haagoni kupiwa kushandisa inobva kumusoro ezvinhu. Chokwadi ndechokuti vanhu vakawanda vanowanzopedzisira generics chete "hama kopi 'nokukanganisika muenzaniso mufananidzo maitiro yepakutanga, uye saka chaiwo mishonga kadhi kuti anofunga purogiramu uye chipimo chemushonga" kaviri "anofanira kuverenga ane ruzivo nyanzvi.

The chigadzirwa repakutanga inokurudzirwa kushandiswa kana:

• murwere nechirwere zvokurwara of kufema wemuTesitamende muchimiro nemabayo, pute kana bronchitis, uye vamwe mishonga musamutsa zvinodiwa mugumisiro;
• murwere kuvaremedza mberi kwemabhakitiriya yomumuzongoza;
• kuongorora kwakaratidza kuvapo endocarditis;
• ari postoperative nguva kukwanisa kudzivisa matambudziko ari muchimiro kuparadzwa zvatichiri ganda uye / kana Kamudzira dzinokosha nhengo;
• kutapuriranwa yomuchipatara akagara pfupa, uye intramuscular majekiseni zvinodhaka-anoreva zvakafanana havana kufurirwa pamusoro pavo;
• Giremu negative kana giremu positive rakapinda kokutsva maronda uye chirwere wakatsamwisa pamwero (kusvika sepsis);
• pane kudiwa matanho.

Nyanzvi Independent chiwanzo chokudavira kuti pane zvishoma chero analogue "Cefotaxime" anogona kuratidza zvakajeka kuratidzwa emuchina akanaka pamwe chirwere cheLyme. Zvinokosha Achiyeuka kuti akarondedzera yepakutanga, pasi nguva dzose chikumbiro, basa kurarama zvakakwana zvakanaka (comments, yakatsaurirwa kuna nuances ari kuchirapa Chokwadi, varwere anoiswa pamusoro forum).

Use uye chipimo chemushonga

"Cefotaxime" mirayiridzo (majekiseni, maererano vamwe vanachiremba uye varwere hainyanyoshanda sezvo mukumisa dropper) iri papi somunhu zvokusarudza kuita vaifarira rwisana zvikuru zvinokonzerwa noutachiona asingaurayiwi. Sezvambotaurwa, kune vatatu reagent pakukurukura nematunhu: ne donhwe aizomupa kana ndege, uyewo kuburikidza intramuscular jekiseni. Rakabatana mitemo nokuti kwegadziriro kushanda Urume hakuwaniki, saka zvakakosha kuziva pachine chimiro chourongwa zvinodhaka.

Mugadziri, zvikurukuru, anokurudzira kutevera algorithm ichi:

• nokuti / fung majekiseni: 1 giremu kuti upfu zvazvichanyungudutswa 4 ml mvura, lidocaine kana novocaine;
• nokuti intravenous jekiseni: 1 g yamarudzi zvinokosha kukurumidza mumvura chena (4 Rine mamiririta);
• nokuti / mu aizomupa: mune guchu maviri magiramu cefotaxime vanofanira kuwedzera 100 ml NaCl (0,9%) kana chete mashanu muzana shuga.

Delivery nguva reagent:

• pa / m majekiseni: 5-10;
• panguva / iri ndege musumo: 5.3 Maminitsi;
• kana kuisa dropper: 50-60 min.

Kukarukureta ose akanaka chipimo chemushonga uye kuronga kuvaka Zvakanyanya Kunaka Panguva Yepamuviri kugamuchira rinoitwa nomumwe. It inorangarira murwere zera uye muviri wake, uyewo mhando chirwere uye padariro kwayo kukura. Uyezve yakabvumira kugadziriswa kwemutemo wekuita yakaitwa kuchirapa munhoroondo.

Kunyange zvakadaro, mirayiridzo zvisinei rinopa mashoko Paavhareji dziine chikumbiro "cefotaxime" chinodhaka. Majekiseni (sezvo rakasanganiswa upfu, anorondedzerwa zvakadzama kumusoro, asi, Sezvineiwo, anenge zvose inofambiswa iri hunodzorwa yokuti jekiseni - muitiro zvinorwadza chaizvo uye kusingafadzi, kunyange zvose kunenge ose mugadziri), zvikurukuru, iri nachiremba nyore ezvinhu, dzinopaza maawa 4-12 uye rimwe dose pamusoro 1-2 magiramu. For dzinonetsa uye subcritical kukosha nezvezviitiko / sumo (pa mwero 2 d ose 4 maawa, asi kwete kupfuura 12 g / zuva).

Pediatricians wokusarudza zvaiitwa nomudzimu muduku muviri uremu murefu uye zvachose muviri maitiro ( "mureza" - kubva ndege majekiseni vaviri nhanhatu; 50-180 MG / kg).

nemishonga

Kana hurukuro imwe medicament "Cefotaxime" (majekiseni ratings hazvina kumeso sezvo donhwe aizomupa, sezvo / m sumo kunowanzoguma uchirwadziwa nokuti chikonzero ichi, sezvo ari "solvent" Kazhinji mashoko procaine kana lidocaine) hazvigoni kunze atypical chiito zvinoumba wegadziriro uye murwere nhengo.

bvumidzwa:

• sema "mhinduro" muchimiro pamwero mukuru urticaria, angioedema kana candidiasis;
• matambudziko ufanane nemudumbu (kurutsa, kuda kurutsa, kashoma - cholestatic jaundice);
• Zvirwere muropa (a ichidonhedzera platelet kuverenga, hemolytic kupererwa neropa uye m. p.).

migumisiro ovhadhozi

Kunwisa kuwedzera zuva nezuva zvinodiwa hwakazara dysbiosis uye encephalopathy; uyewo zvichida achiita ganda kusawirirana.

The chikuru Basa iri nechokwadi kuti chemabhazi reagent hurukuro kupinda mumuviri. Uyezve matanho zvinokosha kudzikamisa nokusungwa mamiriro nokushandiswa desensitizing pharmacological zvigadzirwa (pamwe zvichiongororwa nachiremba).

Maererano mugadziri contraindications

Maererano mashoko anopiwa yepamutemo okuti, "cefotaxime" (majekiseni vana, kazhinji ushandiswe pashure kusvika mwedzi 30., vasati vava kusvika I / aizomupa) hazvifaniri kushandiswa:

• panguva pamuviri;
• hypersensitivity kune zvimwe;
• Panovhurwa uye yokugumisa svota;
• Kana Zvikamu zviri enterocolitis kare kumiririrwa munhau.

zvinodhaka kwavatori

In chepakutanga mutungamiriri chinotaura nezvokuti vamwe mhinduro pasi chero ezvinhu haafaniri kupiwa pamwe chete (kubva mudziyo medical) ne asingaurayiwi rinoreva "cefotaxime".

Majekiseni (nokushandiswa donhwe tichitarisa pharmacological kusakarongeka pamwe zvinoumba zvimwe zvinodhaka, hapana chakasiyana / m jekiseni), zvikurukuru, kungakonzera kukuvara itsvo, kana "taura" anorondedzerwa gadziriro kuita chero aminoglycoside kana loop diuretic. Uyewo, interlocks tubular secretion tunodzivisa zvakasimba kurega muitiro kupiwa reactant uye zvinosimudzira zvibereko zvayo yevasungwa.

The akabatana antiplatelet uyewo chisingadiwi nokuda mukana ropa.

Special kurayira nzvimbo

"Cefotaxime" (tableted analogs, maererano wongororo uye mhinduro dziri zvishoma inobudirira) dzimwe nguva chinokurwadzai venhema Kumbusa mharidzo uye "spoofs" weti kuongorora kuti shuga wechokwadi.

Kana kwenguva refu kurapa metering chinoumba Zvinoumba Ropa yaifanira kwete asingasviki 1 nguva mumazuva 10.

Mumazuva kurapwa okutanga hakuiti haabatanidzi wakaomarara muchimiro manyoka. Uye, characteristically, analoginen "Cefotaxime" akadaro (vana pasi makore 12 nezve "understudy" haina varumbidzwa), sezvo "Fagotsef" navanachiremba mufananidzo yakafanana zvikuru ishoma.

Kunwa doro munguva kurapa pahwaro ari reagent iri zvachose wairambidza.

Ndeupi chaizvoizvo zvineringanidzo "Cefotaxime" kutokurudzira kushandiswa kuzvimirira nyanzvi?

Comments pamusoro "Sefotake" uye "Tsefantrale" ndi pakati zvinorondedzerwa pharmacological chigadzirwa yakavhenganiswa. Kutonga nezvinooneka wongororo yavo chinangwa vaiita kakawanda kupfuura kunyora mushonga mirayiridzo kutenga chete chete "Tsefabola" kana "mutero-on-makwikwi." Zvisinei, vamwe varwere chiwanzo chokudavira kuti mishonga zvinokonzerwa ivhu anotaurwa havaratidzi chinorondedzerwa uye mukana pakati kukura atypical siyana disproportionately kumusoro.

Apo forum mubvunzo wakamutswa kuti anobaya "cefotaxime" kuti haana kukuvara, vanachiremba vakawanda zano:

• bvunzo, uye haisi mhinduro kana kusagadzikana chaiyo chirungiso (kana chirwere chiri kuramba uye procaine rakasanganiswa upfu, ipapo chikonzero chokudavira kuti kunetseka - migumisiro chisimbwa pane zvakananga migumisiro nenhumbi);
• ngaatsvake munhu akadzikama kumwe.

Analysis siyana zvinoratidza kuti vakawanda "kuremekedza" pakati anoreva zvakafanana paakavapa "The Lorax." Zvisinei, asati yaitsiva mumwe reactant mumwe vanofanira nguva dzose kubvunza nyanzvi.