Mushonga 'Pronoran'. Mirairo yekushandiswa

Mushonga we "Pronoran" (analogo yemishonga yakadai se "Tasmar", "Selegilin", "Parkon" nevamwe) inosanganiswa muchikwata che anti-Parkinsonics. Izvo zvinoshandiswa zvinoshandiswa ndi pyribedil. Mishonga inowanikwa mupepeti.

Mushure mekudya, izvo zvinoshandiswa zvinoshandiswa zvakakurumidza kubva mumagetsi. Iyo yakanyanya kukanganiswa kwemishonga inoonekwa mushure meawa. Kugadziriswa kwepurogiramu kwebhuroti "Pronoran" kunopa kusunungurwa zvishoma nezvishoma kwezvinhu zvinoshanda. Mucherechedzo wokurapa wemishonga unoenderera kwemaawa makumi maviri nemana.

Kufananidzira nzira yekuita kwechirwere "Pronoran", murayiridzo wekushandisa unoratidza kukwanisa kwayo kushandisa simba revasodilating (kuwedzera kupararira kweropa mumidziyo mumakumbo ezasi). Chirwere ichi chinokonzera dopaminergic kukurudzira kwemaitiro emagetsi eortex maviri panguva yokurara uye panguva yekumuka, uye inobatawo mabasa akasiyana-siyana anotungamirirwa neDopamine.

Mushonga we "Pronoran" murayiridzo wekushandisa unokurudzira chirwere cheParkinson se mono mishonga mumhando dzakakomberedzwa nekudengenyeka, kana sechikamu chetachiona chakaoma (zvakare kana pakutanga kwechirwere mumhando dzinofambidzana nekudengenyeka). Chirwere ichi chinorayirwa sechimwe chechirwere chechirwere chechirwere chekuziva kugadzirisa kwechirwere chekusingaperi uye neurosensory kusagutsikana nechekukwegura kwekukwegura (kusanganisira kuyeuka uye kuvhara kwekucherechedza). Zviratidzo zvinosanganisira zviratidzo zvehutachiona hwehupenzi hwechimiro (chinosanganisira kuderedza kuonekwa kwemaonero, kuderedza kusiyanisa, kuderedza nzvimbo inoonekwa). Sekuwedzera kwerapi, mushonga we "Pronoran" mirayiridzo yekushandiswa inokurudzira kupatsanurwa kwepakati nepakati kunobatanidza nekudzikisa zvipembenene zvemucheto wakaderera.

Hapana mishonga inorayirwa kuwira, hypersensitivity kune zvimwe zvinokonzera, yakaoma myocardial infarction nemamwe mishonga yemwoyo. Mushonga we "Pronoran" murayiridzo wekushandisa haugoni kutora nguva imwe chete neuroleptics, ine simba rakasimba remapurisa (kunze kwechirwere "Clozapine").

Pamusana pekushaikwa kwemashoko akatendeka pamusoro pekushanda nekuchengeteka kwekushandisa kwechirwere panguva yekuzvitakura uye lactation, haisi yakanyorerwa vakadzi vane pamuviri uye vanokanganisa.

Kutora mishonga "Pronoran" kunogona kukonzera kufara, kurutsa, kushungurudza. Izvi zviratidzo zvinopedzwa, kazhinji mushure mekugadzirisa maitiro. Mune zvimwe zviitiko, mishonga inogona kukuvadza kugona, kusawirirana kwepfungwa (kuvhiringidzika, kuzvidya mwoyo). Sezvo mutemo, zviratidzo zvinopera mushure mokunge mishonga ichigadziriswa. Kakawanda kazhinji pane inogona kuva nebasa reBP kana kuti orthostatic hypotension, iyo inokonzerwa nayo. Mishonga "Pronoran" (kuongororwa kwevarwere uye nyanzvi inopupurira pamusoro peizvi) inoshandiswa mune dzimwe nguva zvakanaka.

Mushonga unorayirwa mushure mokudya, mukati. Matafura haafaniri kuvharwa. Mushonga wacho unomedzwa wakakwana, wakanyudzwa mumhepo yakakwana nemvura.

Nokuda kwezvinhu izvi zvose zvinoratidza (kunze kwechirwere chePasinson), chirongwa chinokurudzirwa chimwe chetabhenakeri (50 milligrams). Tora mishonga kamwe chete pazuva. Kana zvichidikanwa (sekubvumirana nachiremba), inobvumirwa kuwedzera kuyerwa nehafu (makumi mashanu emamiriyoni kaviri).

Sezvo monotherapy yePalinson's disease, 150-250 milligrams (mahwendefa matatu kusvika mashanu) pazuva inorayirwa. Sechikamu chechirongwa chekubatanidza, muyero wemishonga "Pronoran" yakaderedzwa kusvika ku100-150 milligrams pazuva (kusvika pamapiritsi maviri kusvika matatu).

Kana murwere ane hutachiona hwehutachiona, chirwere chinopesana nehutachiona chinorongedzerwa panguva imwe chete nekutora mishonga.

Kushandiswa kwechirwere "Pronoran" kunofanira kuongororwa nenyanzvi.