Parvovirus chirwere kuvana: zviratidzo, kurapwa, matambudziko, kudya

Zvinosuruvarisa zvirwere haringanzi vaiona husiri nyore kuwana. matambudziko akafanana dzakaona kakawanda muna chiremba tsika. Maererano Statistical zvidzidzo, kuti zvevakomana, kazhinji kunyorwa parvovirus utachiona vana.

Kakawanda chirwere chacho munyoro. Zvisinei, zvinhu zvakadaro kunogona kuva nengozi zvikuru. Ndokusaka vabereki vakawanda vanofarira ruzivo nezvechirwere ichi. Chii chiri chikonzero? Ndezvipi zviratidzo parvovirus chirwere rokutanga? Zvinetso zvipi zvinogona vasangana panguva kurapwa? Pane inoshanda matanho? Mhinduro dzemibvunzo iyi ichava kubatsira vaverengi vazhinji.

Parvovirus chirwere: chii?

izwi zvakadaro mushonga ano rinoshandiswa kutsanangura kusachengeteka kukuru zvirwere icho pamwe maronda erythroid mwongo uye ukuwo, kwenguva kusagadzikana hematopoiesis kwendangariro.

Kakawanda chirwere parvovirus utachiona vana. Zviratidzo zvacho zvingave zvakasiyana kubva tembiricha kumuka uye vakawanda zvakawanda zvive uye kupedza erythema, arthralgias uye kunyange aplastic zvinetso. Asi vakuru vakaita chirwere kunoitika ndoda kakawanda.

The kukonzera chirwere

Utachiona hwakakura parvovirus chirwere - munhu parvovirus B19, raiva mhuri parvoviruses. Zvinokosha kucherechedza kuti chete utachiona kugozha ngozi vanhu. Pakazosvika nzira, causative mumiririri sezvayakawanikwa kuEngland muna 1975, panguva tsvakurudzo ropa. The zita "B19" wakagamuchira kubva serum yokuenzanisira, izvo zvakanzi pakutanga dzoga.

utachiwana Izvi duku, kuti dhayamita asingasvavi kupfuudza 20-25 nm. Haana yokunze goko, uye ichazivikanwa noku icosahedral capsid fomu. Structural mapuroteni komberedza mumwe "+" uye mumwe "-" DNA. Zvinofanira kucherechedzwa kuti tisawirirane ichi utachiwana rakanyatsojeka nemishonga kwokunze kwezvakatipoteredza - unogona kukurira kutonhora 60 madhigirii kwemaawa 16.

B19 utachiwana hakusi kushingaira pachinhu mhuka. Under Murabhoritari mamiriro unogona kurimwa chete nokushandisa erythrocyte aizotangira masero, izvo zvinobva kwevanhu mumwongo achiine rukuvhute tambo, kana fetus chiropa.

zvirwere izvi kuitika chero nguva yegore, asi panomuka vakawanda nevakawanda yechando yomunakamwe. Panguva denda muzvikoro uye nemamwe masangano achirwara anenge 20-60% vana. Zvisinei, vakawanda vaiva neutachiona chirwere kunoitika pasina oneka zviratidzo.

kutapukirwa nzira haisi aizvinzwisisa. Zvinofungidzirwa kuti unogona kuti utachiona panguva kwaaita mutakuri chirwere, asi chete kana chirwere chake chiri padariro viremia (utachiona vachishingaira Anowanza munyama). Nemavhairasi nezvimedu akasunungura kupinda nharaunda pamwe chakavanzika uye madzihwa kubva yokumusoro kufema turakiti. Uyezve, utachiona hunogona kutapukira pamwechete neropa kubva mai mwana panguva pamuviri.

Nokuda kwazvo kuparadzirwa utachiona, vabereki vakawanda nhasi vari kufarira mubvunzo kuti chii zviratidzo parvovirus hwemukondombera achabatsirwa. Treatment, matambudziko, dziviriro - ichi zvose zviri mashoko anokosha chaizvo kuti unofanira zvachose kuverenga.

pathogenesis chirwere

Parvovirus chirwere muvana hunovapo mumatanho maviri. In wokutanga kutotanga pane chinoshingaira utachiona kuberekana, kudhaka, uyewo kusarudzwa nemavhairasi inoramba kupinda kwezvakatipoteredza (varwere zvakanaka panguva ino vari zvikuru chinotapukira).

mazuva matatu mushure muviri utachiwana kuonekwa nevakawanda zviratidzo kudhaka, izvo vakafanana vanhuwo kurwara kana kuchitonhora. Zvikurukuru, varwere chokunyunyuta pamusoro chills, zvishoma nefivha, kurukutika uye tsandanyama marwadzo, achirwadza, zvishoma kuvaviwa, nomusoro. Around iyoyi, paiva zvishomanana kuderera Chizenga pamwero, huchavapo kwemazuva 7-10. Kudzidza ropa kunogona kuonekwa munyoro neutropenia, thrombocytopenia uye node.

Mushure anenge 17-18 mazuva pashure chirwere anotanga danho rechipiri chirwere. Kubereka uye utachiwana voga wakagumiswa. 20-22 zuva mwana atore maitiro ganda mapundu, uye kunyange pashure pemazuva mashoma - marwadzo majoini. Ukuwo, zviratidzo izvi hadzisi dzose nyaya - vamwe vana vanotambura nechirwere sechinhu chakajairika chirwere.

Parvovirus chirwere muna vana nevakuru yechipiri chokutambudzika achabatsirwa pagadzirwe dzakananga antibodies - immunoglobulin M uye G, mazita zviri zvikuru kuti zvakakodzera kuongorora chirwere. Sezvineiwo, zviri immunoglobulins G zvinochengeterwa muropa kwenguva refu, dzimwe nguva muupenyu. Laboratory kudzidzwa zvinoratidza kuti vanopfuura hafu yevagari vepasi ine antibodies izvi, kunyange zvazvo vakawanda vavo chirwere kwapfuura zvachose kuzviona.

Varwere vanenge kwazvo kupererwa, kana immunodeficiency (kusanganisira HIV), uchatamisa chirwere zvakawanda kunzwisisa. Kazhinji pamusoro yaitwa parvovirus basa vakachengeta nokuparadzwa zvikuru mumwongo uye nokudaro kutyora chakaipa dzinotsanagura hematopoiesis kusvikira ezvinhu upenyu pangozi. Uyezve, mune varwere kushayikwa dziviriro yezvirwere mumuviri pezvakaitwa hadzina wakagumiswa viremia, nemavhairasi kuberekana mberi, achiperekedzwa zvikuru maronda muviri.

rwarisa erythema

Parvovirus chirwere muvana (mufananidzo) kunowanzoguma nechitarisiko erythema. ezvinhu akadaro anonzi vakawanda nokuratidzwa chirwere. Uyezve, kazhinji vachinzi "chirwere wechishanu". Zita iri zvakaitika mukupera kwezana remakore rechi19, sezvo yakafanana chirwere mumwe matanhatu rakajairika zvirwere, ayo achiperekedzwa ganda kuratidzwa.

Kakawanda, zvinoita sezvo parvovirus chirwere Vana - imwe kuputika riri muchimiro mavara akajeka uye mavara makuru kuonekwa kunyanya pamatama (chiratidzo ichi anonzi "nembama padama"). Kakawanda, okusafunga maculopapular, asi dzimwe nguva kunogona kuva vesicular kana Hemorrhagic. Vamwe vana vanogona kushivirira utachiona nyore, apo vamwe vakanyunyutira chakakomba kuvaviwa. The mapundu rinopararira nokukurumidza pamusoro muzvidimbu asi kazhinji kacho haazombotaurwi roga pashure pemazuva mashoma.

Kunyange zvakadaro, mumakore mashomanana mavhiki, mugamuchire kudzokororwa kwemakomo. Kakawanda izvi zviri kuitika tikafunga kurovedza muviri, overheating, hypothermia, kushambira, rakapinza kuchinja kwemamiriro okunze kana pasi anoshungurudza ezvinhu.

Chenjera chearthritis uye arthralgia ne chirwere

Pakarepo kuchitaura kuti mwana ane parvovirus chirwere haawanzopiwi achiperekedzwa kwemajoini chirwere. Kunyange zvakadaro, kuomesa ichi ichiri zvichibvira, uye kazhinji richiwanika munyika kuyaruka (vasikana vari tichikurumidza chiitiko ichi).

Joint kukuvara kunogona kuitika zvose pamusoro mukuru dzipi akabatwa chirwere, saka kuva chete kuratidzwa kwayo. Inonyanyoshandiswa kuchengetwa kukuvara majoini chiningoningo, ruoko, neketani dzomumakumbo mabvi, kunyange iri dzidziso chirwere anogona kukonzera kuzvimba chero rwakashodoka. Dzimwe nguva varwere vane arthralgias, achiperekedzwa mangwanani kuomarara. Kunyange zvakadaro, zvinoita uye zvizere kukura ehosha.

Ndizvo mune zvimwe zviitiko kwakafanana parvovirus utachiona vana. matambudziko aya, Zvisinei, hazvirevi kunotoreva kuparadzwa articular shwashwa uye kazhinji zvakaitika shure shomanana pachavo. Apo neapo marwadzo uye kuomarara pakati mapfundo inoramba kwemwedzi, dzimwe nguva kunyange makore - mune nyaya idzi, mamwe chirwere uye dzokurapwa matanho.

aplastic dambudziko

Parvovirus chirwere iri kazhinji mhaka anonzi aplastic dambudziko. Zviri tsvarakadenga nengozi ezvinhu, icho pamwe nokuvhiringidzirwa kwomuzvarirwo hematopoiesis. Kune mamwe mapoka ngozi, kusanganisira mukana ane dambudziko iri yepamusoro zvikuru. Zvikurukuru, mumugariro anowanzoonekwa kuchengetwa varwere chisingaperi hemolytic kupererwa, autoimmune kupererwa neropa, thalassemia, fermentopathy. Zvinhu Risk zvinosanganisirawo jeko muchitokisi kupererwa neropa uye paroxysmal kuzvirotera hemoglobinuria uye nenhaka microspherocytosis.

Zvaipesana hematopoiesis - izvi zvinogona kutungamirira vana parvovirus hweHIV. Zviratidzo aplastic dambudziko - wakaomarara kupererwa, icho pamwe chete zvikuru simba, hope, uye nemuumbi pallor ganda. Kudzidza, ungawana kuti erythroid masero mumwongo hatisi. Kazhinji pane rakapinza ichidonhedzera Chizenga pamwero kune pasi, kutyisidzira upenyu zviratidzo. Muzviitiko zvakadaro, hazvibviri kuita pasina ropa.

Zvinofanira kucherechedzwa kuti akapoteredza aplastic dambudziko pane chinoshingaira viremia - the nemavhairasi muwande nokukurumidza, kupinda muropa uye kupinda mune dzimwe nzvimbo dzomuviri. Varwere chirwere ichi vari vatakuri chirwere.

Intrauterine noutachiona uye nemigumisiro yayo

In gynecological uye obstetric tsika dzimwe nguva yakanyorwa fetus parvovirus hweHIV, zviratidzo izvo chiziviso zvakawanda zvakaoma. Pakarepo zvinokosha kuziva kuti kakawanda, utachiona mai panguva pamuviri haiiti kuti chirwere ari mudumbu uye hapana zvinokonzerwa pamusoro mudumbu asina.

Kunyange zvakadaro, njodzi kuchiripo. Maererano Statistical Data uye wongororo kuti vanoita, kazhinji utachiona kunotungamirira yematambudziko rokutanga kana chechipiri trimester akazvitakura. Chirwere fetus munyama (zvikurukuru normoblasts uye erythroblasts) munenge 13% dzokushungurudzwa kukonzera vaingoerekana pamuviri.

Pane mamwe matambudziko. Tikafunga kukura chirwere mune dzisiri zvirwere hydrops mwana hwapedyo. Unogona kugamuchira zvikuru kupererwa neropa uye mwoyo kukundikana, zvichitungamirira rufu azvarwa.

Ukuwo, kana pamberi chirwere zvinogoneka kuziva vachiri Danho (kushandisa Ultrasound) uye vane akakodzera kurapa, mwana azvarwa utano pasina matambudziko (dzimwe nguva lagging mumashure kwomuviri, kufuta kunonoka). Mune zvimwe zviitiko, mwana achangobva kuberekwa akaonekwa vachiberekwa kupererwa neropa uye hypogammaglobulinemia, izvo, zvisinei, muri inowirirana upenyu uye rinorapika.

Pakadaro, kana mukadzi ane mimba ari kuonana vanayo vanhu, Zvinokurudzirwa kuti tiite nguva dzose Ultrasound bvunzo, uyewo kuti vape ropa kuona padanho Arifa-fetoprotein uye titer pamusoro antibodies - zvinobatsira kuziva dambudziko achiri pachikuva, uye inowedzera mikana rakabudirira uye kwakakwana kupora.

Modern nzira nechirwere

Parvovirus chirwere muvana uye vakuru kunoda kwazvo kuongorora chirwere. Chokutanga, chiremba anounganidza nhoroondo uye anoyera. The kunotoda mufananidzo hazvisi kufanana nevamwe zvirwere, saka kuva nechokwadi kuti kuitisa okuwedzera rabhoritari nemiedzo.

Zvikurukuru, mufambiro ropa hwomwana ivhu uye nyama kuyera titers nezvevamwe immunoglobulins M uye G. Sezvo mutemo, uwandu IgM simuka pazuva rechitatu pashure activation yacho chirwere. Asi yakawanda immunoglobulin G ari kuchengetwa kunyange gore pashure chirwere. Kana aplastic Shamhu ari ivhu akatsunga kwete chete refu mari mapuroteni asiwo utachiona uye ayo DNA. Uyezve, mwongo zvidzidzo vanogona kuzviona erythroid hypoplasia uye kuvapo noruzhinji vaRafa erythroblasts.

In nechirwere kwezvirwere Varwere immunocompromised ari antibody haigoni kuwanikwa, asi zvinokwanisika govera vakawanda nemavhairasi inoramba.

Kana totaura nechirwere pamusoro intrauterine noutachiona, pane kudiwa kwazvo Ultrasound bvunzo (kubatsira wanikidza fetus hydrops). Uyewo vakaperekedza rabhoritari kuedza ropa raamai uye Líquido mvura kuvapo nemavhairasi DNA uye yakananga antibody.

Parvovirus chirwere muvana: mabatiro

Paunoona kunyange zvishoma nokufungirana kuvapo chirwere yakadai vanofanira kuona chiremba. nyanzvi chete anoziva sei kurapa parvovirus hutachiona.

Zvinokosha kucherechedza kuti vanyoro nguva mwana asingadi kunyange zvinoda muchipatara. Kunyange zvakadaro, vanofanira tikadzivisa kukurukurirana ayo vanhu hwakanaka, sezvo danho rokutanga chirwere iwayo chinotapukira. Sei kurapwa kumba parvovirus chirwere kuvana? Komorowski, inozivikanwa wevana, rinokurudzira mubhedha zororo. Mwana anofanira zororo, tikanwa zvinwiwa zvakawanda (kubvisa zviratidzo kudhaka). Asi rinoita kutamba uye kurovedza muviri zviri contraindicated. Vabereki vanofanira kuomerera nemitemo utsanana, kugeza maoko ako pashure kuonana mwana, kuita kugara akanyorova kuchenesa, kuchinja mubhedha wakaisvonaka uye t. D.

No zvisinganyanyi kukosha chikamu kurapwa zvokudya. Kana parvovirus chirwere mwana anoda zvokudya zvinovaka muviri mupfumi pamatunhu-mafuta uye nyore digestible chikafu. Zvinokoshawo kuti utarisire kuti ndiro chipo mune zvakakwana mari mavhitamini uye zvicherwa kuti aifanira kusimbisa zvirwere (kuva nechokwadi kuti unosanganisira michero nemiriwo ari Muterere). Uyewo, zvokudya zvinofanira kuva akapfuma simbi uye mhuka mapuroteni, sezvo chirwere iri pamwe kupererwa neropa uye Chizenga mumatunhu kuderera.

Kazhinji, chirwere zviratidzo inonyangarika voga pashure pemavhiki 1-2. Kunyange zvakadaro, mune zvimwe zviitiko, zvinoda chaiwo kurapwa. Somuenzaniso, kana ari kushanda zvinoda nefivha antipyretic zvinodhaka ( "asipurini", "paracetamol" "Analgin" and said.). Kana murwere dzakabudirira yemajoini vane zviratidzo izvi zvikaramba zviripo kwevhiki dzakati wandei, zviri kushandiswa here kuti nonsteroidal Anti-anogumbura zvinodhaka ( "Ibuprofen", "diclofenac", "Nurofen" uye zvichingodaro. N.).

Kana totaura pakurapa varwere immunocompromised, zvinokwanisika intravenous immunoglobulin, rine antibodies yakananga kuna B19 utachiwana. Nzira iyi haripi mushonga wakakwana, asi zvinobatsira kudzvinyirira basa chirwere. Zvakakomba aplastic dambudziko kunoratidza kuti matsvuku eropa kuwedzerwa.

The chirwere chimiro parvovirus chirwere

Mune zvimwe zviitiko, kana untreated kana isina kukodzera kurapa anova chisingaperi rikwanise chimiro chirwere. mamiriro akadaro ngozi zvikuru, sezvo zviratidzo aro zvishoma raidudzwa. Zvakaoma rokuongorora uye kurapa. Chirwere parvovirus chirwere iri achiperekedzwa kupererwa, kunoitika muna mafungu. Kazhinji, chimiro ichi chirwere inova mhosva idiopathic mwongo aplasia erythroid mafupa. Rasa chirwere ichi ndicho zvakaoma. ropa uye kwokubatsira immunoglobulin kubatsira kuchengetedza zvakajairika nemuviri.

The chikuru nzira muzvidzivirire

Zvinogona kucherechedzwa kuti parvovirus utachiona ari mwana kunogona kuva zvechokwadi ngozi. Saka, vabereki vakawanda vanofarira mibvunzo pamusoro kana zvinobudirira mishonga dziripo.

Zvinosuruvarisa kuti mushonga pamusoro utachiwana saka kure haako. Asi nokushingaira nezvokumwe mukana mushonga kuti aizorega kukonzera kukura chirwere, asi vane immunogenic ehupfumi. Zvinogoneka kuti mushonga wakadaro vachiri kuonekwa munguva yemberi iri pedyo.

Mune zvimwe zviitiko, vanhu kutevera kuonana neutachiona kutokurudzira kurapa pamwe intravenous immunoglobulin. Zvikurukuru, nzira dzakadaro vanoonekwa pamuviri, varwere chirwere hemolytic kupererwa neropa kana Immune Deficiency. Zvisinei nhasi haina chaizvo kutsunga, kana prophylaxis yakadaro inoshanda chaizvo.

The chete nzira kudzivirira utachiwana kushaya kuonana vatakuri chirwere, izvo, zvinosuruvarisa regai kuva nyore kudaro. Uyezve, Zvinokurudzirwa kuchengeta zvakanaka utsanana, akadai maoko Washing pashure kuonana varwere, vasati vachidya, uye zvichingodaro. D.

Varwere chisingaperi zvirwere, uyewo vaya vakaona aplastic dambudziko zvinoshingaira Distributors hweHIV. Ndokusaka vanoda nokukurumidza muchipatara kusvika kutapuriranwa dhipatimendi uye kushaya zvakananga vachionana vanhu hwakanaka kusvikira apedza mushonga.