Sertoli masero (sustentotsit): shanda

Vakuru anokonzera kubereka nevanhu, akadana testes. Ivo anobudiswa zvepabonde masero - dzisingaoneki uye mahormone, zvakadai testosterone. The anatomical uye histological maumbirwo testes vari vanhurume yakaoma, sezvo zvitunha izvi vanoita akawanda mabasa. Vakanga vakatakura spermatogenesis - paumbwe uye kukura utachiona masero. manhu uyewo kuita kwemakemikari anobudiswa chaitika. Vari riri chaiyo homwe cutaneous - scrotum. Pane anodzokororwa chaiyo tembiricha, riri zvishoma kuvatumwa mune dzimwe nhengo dzomuviri.

Testes vane elliptical chimiro, saizi wavo anenge 4 masendimita refu uye 3 paupamhi. Kazhinji, pangava zvishomanana asymmetry ari gonads. Mumwe zai goko yakakamurwa partitions ive muzvizhinji kuti zvidimbu. Ane migero convoluted seminiferous dzichiumbwa testicular plexus. efferent ducts ayo kupinda epididymis. Pane aumbwa unorema dzisingaoneki - musoro. Gare gare - channel vanobatanidzwa mune vas deferens, iyo rwunotumirwa dundira. Uyezve, havana chokuwedzera uye zvinopfuura vamwe nhengo ngakuite dzokubereka nadzo - kweprostate. ichi pamberi, gwara achiumbwa munyika ejaculatory mutsinga dzinofamba nemukaka, rine nzira yokubudisa munzvimbo yacho urethra.

Histological nemamiriro manhu nevanhu

Male gonads ine spermatic tambo, uye interstitial tishu. Kunze cover dzavo albuginea. Iye chinomiririrwa connective batana tishu. Albuginea spliced nomuviri. Side kwayo richikora kuumba mediastinum testis. Panguva iyi, connective zvinyama rakakamurwa kuva muzvizhinji kuti tambo. Vanoumba lobules mukati vari convoluted tubules. Ivo vanomirirwa inotevera STRUCTURAL dzakabatana:

1. Sertoli masero - sustentotsit. Pamwe nemamwe masangano munyaya paumbwe ropa-testis nokuidzivirira.
2. Masero, kuburikidza icho vakatakura spermatogenesis.
3. Myofibroblasts. mamwe zita ravo - masero peritubular. The chikuru basa myofibroblast - ndiko kuti tibu- kukwidziridzwa pamusoro seminal mvura pamusoro crimped makwara.

Mukuwedzera, sechivako zai ane interstitial tishu. Zviri pamusoro 15%. Interstitial zvinyama chinomiririrwa zvinhu zvakadai Leydig masero, macrophages, capillaries uye zvichingodaro. D. Kana convoluted migero vane basa paumbwe dzepabonde masero, pane paumbwe uye kugadzirwa kwevarume mahormone.

Sertoli masero: mamiriro

masero Sertoli vane elongated chimiro. saizi yavo vanenge 20-40 microns. Uyu kumbonyanya chikuru STRUCTURAL dzakabatana zvakasiyana vanonzi kutsigira masero. Mune cytoplasm masero aya rine organelles zhinji. Pakati pavo:

1. Core. It ane kwemashifiti, dzimwe nguva - peya serin'i. The chromatin ari musimboti iri kuparadzirwa vanoiswa.
2. Smooth uye mafungu EPS. Chokutanga - ndiye anokonzera kugadzirwa kwezvinhu steroid mahormone, wechipiri - chinopa mapuroteni usage.
3. Golgi midziyo. Nemhaka organelle ichi, pane wokupedzisira kwetunhu, kuchengetwa uye kubviswa zvigadzirwa.
4. Lysosomes - vanobatanidzwa mune phagocytosis.
5. Microfilaments. organelles izvi zvinobatanidzwa munyaya kuibvisa pamusoro dzisingaoneki.

Uyezve, sero rimwe rine Sertoli mafuta usanganidzo. Sustentotsitov garo iri masvingo seminiferous tubules, uye muromo - zviso mu lumen zvavo.

Sertoli masero: shanda

Sertoli Sero rimwe zvakamisa hurongwa achiumba convoluted seminiferous tubules. Zvinokosha zvikuru, sezvo rinobatanidzwa nedanho spermatogenesis, uye kwetunhu varume mahormone. Pane zvinotevera kushanda Sertoli masero:

1. Trophic. zvinhu izvi zvinopa saibva dzisingaoneki masero pamwe okisijeni uye zvinovaka muviri.
2. Unodzivirira. Sero rimwe nerimwe rine cytoplasm lysosomes - organelles kuitawo phagocytosis. Ivo Sechipanji uye bikurudza kuti manyowa zvigadzirwa Somuenzaniso, zvimedu spermatids akafa.
3. Kupa ropa-testis nokuidzivirira. basa iri kunosimbiswa nemashoko pedyo sero-sero kuonana. The chipingamupinyi chinodiwa vaparadzane vanhurume masero kubva ropa uye zvinhu zviri mairi. Uyezve, rinovatadzisa ari kupinda kuti dzisingaoneki maantigen mu plasma. Izvi kunoderedza ngozi yokuva autoimmune kuzvimba.
4. Kwemakemikari anobudiswa basa. Masero Sertoli zvinobatanidzwa paumbwe bonde mahormone.

Sustentotsity zvakakodzera kuti paumbwe uye dzigadziridzwe chaiye ezvinhu umo dzisingaoneki kutanga zvakanaka. Zvinozivikanwa kuti Ionic Zvinoumba Sertoli masero akasiyana plasma. yavaibvisa wevasungwa dererei, uye potassium kugutsikana, nekusiyana, vakawedzera. Uyezve, muna Sertoli masero synthesize zhinji pakugadzira zvinoshingaira zvinhu. Pakati pavo - the prostaglandins, cytokines, follistatin, kukura zvinhu uye kupesana, opioids, etc ...

Nerevane maumbirwo Leydig masero

Leydig masero ndiwo mugove testicular interstitial tishu. saizi ravo microns anenge 20. The Munhurume gonads vanopfuura 200 * June ¹⁰ Leydig masero. The STRUCTURAL zviri zvinhu izvi huru denderedzwa neerekitironi foamy cytoplasm. Rine vacuoles ane mapuroteni lipofuscin. Zvinonzi inoumbwa ne kuora kwemafuta iri nguva yacho kwetunhu steroid mahormone. Mukuwedzera, muna cytoplasm ane 1 kana 2 nucleolus ine RNA uye mapuroteni. The chikuru basa Leydig masero - ndiko testosterone. Mukuwedzera, vari munyaya kwetunhu activin. fuma iyi kunomutsa kugadzirwa FSH muuropi.

Chii Sertoli muchitokisi chirwere?

Mumwe zvisingawanzoitiki nezvirwere ngakuite dzokubereka nadzo ndiyo Sertoli muchitokisi syndrome. Kuratidzwa chikuru chirwere ichi runoonekwa kuti kushaya mbereko. The chirwere wakabatana vachiberekwa anomalies, sezvo vakachengeta aplasia (chinokosha rutapudzo kana kusavapo) kuti embryo testicular tishu. Somugumisiro nokuvhunika iyi seminiferous tubules kutanga. The chete chaikosha asina kukuvadzwa - ndiye Sertoli muchitokisi. Chimwe zita chirwere ichi - a chirwere del Castillo. Chikamu Sertoli masero achiri kaviri degeneration Zvisinei, vakawanda vavo - vari muupenyu. Pasinei neizvi, epithelium pakati tubules atrophied. Spermatozoa zvokurwara ichi havana kuumbwa.

Vanotaura pamusoro mashandiro Leydig masero

Kana zvaparadzwa Leydig masero kwakakanganiswa chikuru basa ravo - testosterone kwetunhu. Somugumisiro, zviratidzo zvakadai:

1. Akaderedza kwetsandanyama.
2. Kusavapo yechipiri bonde zvatariswa (kukura kwomuviri bvudzi varume mhando, izwi).
3. Kutyora libido.
4. Shoma mapfupa arambe achirema.