The mushonga "Akineton": mirayiridzo kushandiswa, tsananguro, wongororo

The vanoshingaira fuma "Akinetona" riri biperiden hydrochloride. Hwendefa rinokwana 2 MG kuti basa fuma. Uyezve, kuvapo mamwe zvinoriumba (zviyo starch, mbatatisi starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, copovidone, karusiyamu rehydrogen phosphate dihydrate, talc, mvura yakachena) anotora zvinodhaka "Akineton".

Mirayiridzo kushandiswa, mufananidzo kunoratidza kuti nehwendefa chimiro mushonga une kushanda ruvara chena, Valium chimiro. Kune rimwe divi pahwendefa pane mukana munhu beveled muchinjikwa chimiro.

1 ml mhinduro rine biperiden lactate mune imwe mari 5 milligrams. Zvimwe zvinoriumba ndiwo: Kubayiwawo jekiseni mvura uye yavaibvisa lactate.

Pharmacological migumisiro

Main chirungiso biperiden - holinoblokator nechepakati chiito.

Matambudziko kunosanganisira mwoyo kugona cholinergic neuronal basa iri striatum, inova STRUCTURAL Unit extrapyramidal hurongwa.

The mushonga kunokonzera ganglioblokiruyuschimi zvazviri, antispasmodic uye mwero kukuvadza M-anticholinergic anokonzerwa panguva arikunze (antispasmodic).

Kushandisa zvinodhaka kunobatsira kubvisa muzvidimbu tremor, izvo unovapo kushandisa cholinergic zvinodhaka (semuenzaniso, pilocarpine) uye catalepsy uye tsandanyama Rigidity pavarwere pakugamuchira neuroleptics. It anokwanisa kufurira nokusagadzikana.

Pharmacokinetics

"Akineton" vakasungwa mapuroteni eplasma pa 91-94%. Plasma Clearance achava 11.6 ± 0,8 Rine mamiririta / Maminitsi / makirogiramu muviri uremu. A chete dose of nomumukanwa Pfungwa ine bioavailability anenge 33 ± 5%.

Zvinoenda zamu mukaka.

Biperiden rinoita zvizere mumuviri womunhu. In weti, nefuma hauna kutsunga mu unaltered chimiro. Mikuru metabolites vane bicycloheptane uye piperidine, izvo goho kubva mutsvina yadzo weti uye.

Elliminatsiya kuitwa maitikiro maviri, pamwe nehafu upenyu (T 1/2) maminitsi 90 muzana rokutanga kutotanga uye maawa 24 - wechipiri chokutambudzika. In varwere vakwegura, hafu upenyu zvinogona kuwedzera substantially.

zvairatidza

"Akineton" rakashandiswa extrapyramidal nepfungwa kunokonzerwa kwokubatsira vamwe mishonga (neuroleptics, antipsychotics).

Uyewo, kuti mushonga inoratidzwa kuti chirwere chirwere chinonzi Parkinson urwere, parkinsonism (mumiririri raitongwa yakasanganiswa kurapa ine hwaro)

Contraindications

Chinangwa zvinodhaka ichi hakuratidzwi kana uri hypersensitive kune basa wemafuta mushonga "Akineton".

Mirayiridzo yokushandisa anoudza kuti mushonga anofanira kudziviswa mune chirwere zvirwere mune murwere akadai prostate nedumbu, angled-kuvhara yemaziso, obstructive zvachinja ura (pylorus stenosis, akafa mitezo ileus Genesi).

Arrhythmia, pfari, zamu kudyisa, vakwegura, nhumbu ndiyo zvinhu umo "Akineton" raitongwa nokunyatsongwarira.

nemishonga

CNS nemishonga zvinozarurwa asthenia, kurukutika, lethargy, utera, chiveve, dzungu, kunzwa hanya, kufunganya, ndangariro vanotaura, kuvhiringidzika, aone zvinhu zvisipo, catalepsy, zvinodhaka nedoro zvinodhaka "Akineton".

Mirayiridzo kushandiswa kutaura divi-zvinokonzerwa uye vane chikamu chiratidzo - mydriasis, nyonganyonga akkommodasie.

Cardio-vascular hurongwa kunoratidzwa rokumuka kwemwoyo mwero (tachycardia); dzimwe nguva - deceleration (bradycardia); kana kushandisa imwe jekiseni chimiro gadziriro - zvinoderedza BP (hypotension).

Pamusoro chikamu zvomudumbu ino - muromo yakaoma, dyspeptic zviratidzo, kupatira.

On chikamu muviri - dzikira vangadikitira.

On chikamu nezvezvimwe zvinetso zvedundira - pavarwere vane akawedzera (hypertrophy) kweprostate gland - zvinogoneka chinetso vanhurume.

Neutachiona: okusafunga paganda, kuvaviwa.

Nzira Use

Nokuti intramuscular, intravenous, uye dzaiita piritsi chimiro wakafanira kugadzirira "Akineton".

Mirayiridzo dzokushandisa kunoratidza kuti kurapa "Akinetonom" kazhinji rinotanga kubva mishonga muduku dose zvikuru stepwise kunowedzera zvichienderana aida kuchirapa kushanda uye kuti nemishonga.

Adults ari kushandisa imwe nomumukanwa muchimiro rokugadzirira kutanga arapwe dose 1 MG 1-2 Kugamuchirwa masikati kana 2 MG rakakamurwa mishonga pazuva maviri. Uyezve, chipimo chemushonga anogona ngazviwedzerwe 8 MG maviri kusvika mana vakakamura mishonga. Zvisinei, dose haafaniri kuwedzera kupfuura 2 MG pazuva. Regai kusapfuudza kunonyanyisa chipimo chemushonga zvinoreva 6 kupinda Th-16 MG kwemazuva mashanu. Single dose injectable zvinodhaka fomu haafaniri kupfuudza 2.5-5 MG. dose ichi zvingadzokororwa pashure hafu yeawa, asi nhamba dzekushumira pazuva haafaniri kupfuudza 4 nguva. The kunonyanyisa dose kuti medicament mu injectable muchimiro 20 MG kwemazuva mashanu. Kana Zvakanyanya Kunaka Panguva Yepamuviri dose zvasvika, ipapo munhu yezwi mabiko "Akinetona kutadzisa."

Asi usakanganwa pamusoro wacho nzira murwere mumwe nomumwe ari pakugadzwa biperidenom mishonga.

Extrapyramidal zvokurwara anomuka nokuda ingestion dzimwe mishonga (antipsychotics kana neuroleptics) zvinoda basa ane pfuma kupiwa rimwe dose of 2 MG nomuromo kana parenterally. Dzokorora kwokubatsira vakati mishonga angava hafu awa ose. Zvisinei, sezvataurwa pamusoro apa, nhamba dzekushumira havafaniri kupfuudza 4 nguva. The zvokuudzwa dose anofanira kukamurwa munhu zvitatu mishonga.

Parkinson chirwere kunosanganisira vachiita mushonga zvakataurwa 6-8 MG muna 2-4 yakakamurwa mishonga kuti zuva, ari dose inogona kuwedzera zvishoma nezvishoma kusvika 6-16 MG.

Children pasi gore chinangwa rinoratidza zvinoita zvinodhaka ari injectable chimiro zvishoma nezvishoma, rimwe dose 1 MG kana 0.2 Rine mamiririta. Kana zera kubva gore rimwe makore matanhatu raitongwa 2 MG kana 0,4 Rine mamiririta. Kubva 6 kusvika 10 makore - 3 MG kana 0,6 Rine mamiririta. dose ichi zvingadzokororwa pashure hafu yeawa chete zvashata. In pamberi nemigumisiro pamusoro kwokubatsira mushonga kunofanira kwakaregwa jekiseni.
Munguva zvokuudzwa chimiro zvinodhaka mishonga zera kubva 3 kusvika 15 makore achitora chipimo chemushonga pakati 1-2 MG mumaawa 1-3 masikati.

Mahwendefa haagoni kunwa usina chawadya, uye iwe unofanira kunwa zvine mwero yakawanda mvura. At panowanikwa pamamiriro divi anokonzerwa kubva zvomudumbu ino anofanira kutora mushonga pakarepo pashure zvokudya, kuderedza kwokuomerwa kukanganiswa Impact zvinoreva "Akineton".

Mirayiridzo zvokushandisa zvinoratidza kuti kune yefodya chepfu mune vakuru mureza kunzwisisa kurapa kuri chinotarisirwa zvinodhaka ichi, uye ayo dose ndiyo 5-Th-Tb-10 MG nokuda injectable siyana, asi chete kacho kuti zvingakanganisa upenyu murwere.

Kana Kusvibisa Organic phosphorus wemisanganiswa biperiden dosing rinoitwa nomumwe zvichienderana kwokuomerwa maronda. Tanga kubva dose 5 MG zvakadyiwa intravenous kutarisira Kutarisirwa akadzokorora kusvikira zviratidzo rinyangarike chepfu.

ovhadhozi

Ovhadhozi kunoratidza raidudzwa anticholinergic matambudziko anokonzerwa mushonga "Akineton".

Mirayiridzo yokushandisa, vanachiremba chaiko kuteerera chokwadi kuti mishonga iyi mamiriro posimptomnaya (munyu pamusoro zvemwoyo uye kufema hurongwa, okisijeni kurapa, hyperthermia kururamiswa, munhu Urinary anobudisa mushonga zvishoma nezvishoma yakatarwa, kana zvakakodzera). Kunoda kutanga imwe cholinesterase inhibitor (physostigmine zvikurukuru) .

kudyidzana

"Akineton" apo kushandisa mamita-holinoblokatorami, zvinodhaka vane antihistamine uye antiepileptic chiito kunonatsiridza kuratidzwa yokupedzisira. Zvisinei, mawa kushanda metoclopramide kunoderedza ayo kuchirapa kushanda. Pane zvachose mushonga kusapindirana pamwe panyaya iyi. Kugadzwa quinidine kunowedzera nguva pangozi yokuita dyskinesia zviratidzo. M-cholinergic mugumisiro kunowedzerwa kana kushandisa levodopa.

Storage uye sero

Kutenga mushonga uyu zvinoda mushonga kuti anopa mishonga. Yokuchengetera "Akinetona" vanofanira kuteerera tembiricha, t. E. Ambient tembiricha haafaniri kupfuudza madhigirii 25 (Celsius akamboona). Tinoda pasingasvikire vana kuti nzvimbo "Akineton".

Manual anopa pasherefu upenyu zvinodhaka - makore mashanu.

Zvokungwarira

Kudomwa biperiden panguva yepamuviri uye achiyamwa (lactation) kunoda kuzviomesera zvairatidza.

Biperiden anogona kusvika mwana kuburikidza mukaka, zvichikonzera kwekanguva kukundikana achiyamwa kuti discontinuation zvinodhaka "Akineton".

Product Rondedzero rinotaura kuti kusarudza kugadzwa biperiden panguva yepamuviri uye lactation kufunga zvingakanganisa mucheche, mudumbu.

Vakwegura anova ngozi nokuda kurapwa pamwe chinodhaka ichi. Saka kugadza "Akineton" boka iri revanhu nokunyatsongwarira.

Kickaha kusavapo chero uchapupu kushandisa kuchengeteka pauduku, ndicho chikonzero kuti hairevi zvinodhaka vana "Akineton".

Description rekugadzirira (murayiridzo Chinyorwa) rinoti yokuti kungwarira kunodiwa kana kushandisa zvinodhaka izvi varwere tsviyo kana fibrillation.

With kushandiswa kwenguva refu anogona mishonga kuyanzva.

Ngozi caffeine chirwere hunosanganisira zvishoma nezvishoma kumira yokurapa "Akinetonom".

kushandisa doro-tune zvinwiwa anofanira kudziviswa panguva mishonga.

Treatment pamwe mushonga uyu zvinoda pakuzvinyima kutyaira motokari uye mitambo zvinhu zvinoda yakakwirira yevasungwa uye kukurumidza psychomotor siyana, sezvo anotakura nayo ngozi nokuda mukana dzungu.

"Akineton". Mirayiridzo kushandiswa. analogs

Anoreva zvakafanana gadziriro ndedzinotevera zvinhu: "Biperiden" "Mendileks" "biperiden hydrochloride".

"Akineton". Reviews

The mushonga iri nyanzvi pakurapa Parkinsonism chakamira pakunodengenyeka zvine vari pabazi iri wakagumiswa pashure pfupi penguva. Anoti zvakanaka akashivirira zvinodhaka "Akineton".

Feedback pamusoro forum kutaura nezvomukana kuratidzwa vamwe marwadzo apo achitora zvinodhaka.

Price "Akinetona". apo kutenga

Mari mhinduro kungava kumativi 800 rubles.

Price zvokuudzwa idzidziso "Akinetona" - 560-580 rubles.