An chirwere autoimmune iri thrombocytopenic purpura

Nokuti nguva yokutanga chinhu autoimmune thrombocytopenic purpura, akarondedzerwa muna 1735 Verlgofa vaicherechedza chirwere mumakore gumi 'musikana. Parizvino pasi zita iri fomu vasanganiswa autoimmune thrombocytopenia, chikonzero autoaggression panguva iyo rotsva. Vanoonekwa Hemorrhagic diathesis pamwe kure kushayiwa maplatelet. Govera chenjera uye chisingaperi chimiro chirwere.

zvinokonzera

Chenjera thrombocytopenic purpura vanotambura kunyanya vana makore 2 kusvika 9 makore. Thrombocytopenic purpura muvana kunoratidzwa kamwe Pazvinotanga uye nokukurumidza kupora. Development kunotoda kurapwa kuratidzwa kazhinji kunoita chaikonzerwa noutachiona rokumusoro kufema turakiti kana zvomudumbu turakiti. Muna 10% kubva Muzviitiko chirwere chokuita kukura varicella utachiona, Epstein-Barr utachiona, majekiseni anodzivirira, BCG immunotherapy. Platelet kuparadzwa nokuda zvirwere kwaiita nhengo pane Zvakaitwa utachiwana.

Chirwere siyana thrombocytopenia zvisingaperi anopfuura 6 mwedzi anonzi idiopathic thrombocytopenic purpura. The mhaka chirwere harizivikanwi. Thrombocytopenic purpura kazhinji anotanga ari kuyaruka, kuyaruka. More nevakawanda vakadzi.

Clinical kuratidzwa kuonekwa zvishoma nezvishoma. Dzinoratidzwa vanotogara-inodzokororwa kana mazhinji kosi yacho chirwere. Pathogenetic Panobva hosha kwakawedzera uye nokukurumidza platelet kuparadzwa kuburikidza autoantibodies kuzorwa navo.

zvekuchipatara mufananidzo

Paganda varwere zviratidzo microcirculatory ropa mhando sezvo punctate petechial mapundu duku subcutaneous hematoma, purpura pamusoro nomumukanwa mucosa. Inozivikanwa nekudeura ropa pamusoro mucous membranes mhino, matadza. Kuchinja paganda kazhinji dziri pamberi pemvura hunde, okumusoro migumo. Yemanyorero paumbwe guru ropa panguva jekiseni nzvimbo. Apo neapo pangava ropa mukati sclera uye the retina, ropa kubva zvomudumbu turakiti. Vakadzi, mune hemorrhages ari ovaries. In kwazvo siyana renal chirwere ropa kunogona kuitika.

Thrombocytopenic purpura kungakonzera matambudziko ngozi dzakadai chepfungwa ropa uye subarachnoid ropa. Mamirire akanaka cuff bvunzo-Konchalovsky murimi-LEED: inotungamirwa hemorrhages mu ganda nzvimbo compression. Node nodes, chiropa uye chirwatata kwete mukuriswe.

Diagnostics

The chikuru chinoratidza murabhoritari ndiko kuti kuderedza uwandu maplatelet. kweropa nguva haina kutyora. Heparin yeplasma yakawedzera. Muzviitiko zvakawanda, pakutsvaga kuwedzera pamusoro immunoglobulin G maplatelet. Pashure chinokosha ropa rinotsanangurwa rikwanise Hemorrhagic kupererwa neropa.

mabatiro

Kana nechirwere thrombocytopenic purpura, varwere vanotanga kurapwa pamwe corticosteroids. Panguva kurapwa, varwere vakachengeta vachiwana yakawedzera platelet kuverenga kusvikira kuregererwa kwakakwana. Kushaya Kushanda corticosteroids uye immunomodulators ushandiswe delagil. Tiine ineffectiveness kuti kuchinja kurapa mukati 6 mwedzi dzinokurudzira achiita splenectomy.

Imwe nzvimbo yokurapa - kwokubatsira yakakwirira mishonga kuti immunoglobulin nokuda intravenous jekiseni nokuda 5 mazuva. Mugadzire izvi inactivate antibodies kuti vasunge uye kubvisa nemavhairasi, kwemabhakitiriya nezvimwe maantigen.

Muna 80-90% dzevarwere vari kwatangwa kupora kunoitika mukati 1-4 mwedzi. Mune zvimwe zviitiko, thrombocytopenic purpura hunogara kusvika mwedzi 12. The chirwere chirwere relapsing: ropa nguva chinjana pamwe nguva kanganwiro.