Rinoreva "simvastatin" mirayiridzo iri kushanda se hypolipidemic zvinodhaka ndohwaJehovha boka, uye statins muri FIs pamusoro HMG-reductase mhando CoA. medicament uyu prodrug, sezvo chimiro chayo aripo namahwindo, unonzi lactone mhete iyo, tapinda munhu muviri hydrolyzed. The mushonga "Simvastatin" (Kuraira pamusoro pokushandisa ichi anotarira) kunobatsira kuderedza ropa kwevari triglycerides uye lipoprotein uye zvachose remafuta akawandisa. Panguva iyoyowo kuva muviri chaizvoizvo rinotanga pashure anenge gumi kana gumi nemana mazuva kubvira pakutanga kushandiswa, uye kufadza mugumisiro kunoitwa mune wechina svondo rechitanhatu.
The mushonga kunyanya muchimiro biconvex kumativi pamahwendefa. The Zvinoumba pellet nechimwe sezvo chikuru vanoshingaira chirungiso ane milligrams makumi simvastatin. Zvimwe zvinoriumba vari lactose, polyvinylpyrrolidone, karusiyamu stearate, cucumber acid, hypromellose, microcrystalline cellulose, butylated hydroxyanisole, ascorbic acid, chibage starch, titanium dioxide, talc uye Macrogol 4000.
Taurira lipid-richikwidibira zvinodhaka "Simvastatin" mirayiridzo Chinyorwa rinokurudzira Somuenzaniso, kunorapwa vanhu chirwere chikuru hypercholesterolemia. Zvisinei, kushandisa mudziyo muchiitiko ichi zvakakodzera chete kana varombo zvokudya. "Simvastatin" mushonga kuri zvakanaka wakanyatsokodzera kuti mishonga hypercholesterolemia vasanganiswa. Zvairatidza uye anosanganisira zvirwere zvakadai hypertriglyceridemia.
Tora mahwendefa aya ari zvachose hazvitenderwi kuti vanhu chirwere chakakomba siyana zvirwere chiropa uye zvakakomba renal insufficiency. Kana iwe uri hypersensitive kuti simvastatin kana ebetsero zvinoriumba nyanzvi akafanana dzinokurudzira kurega kutora lipid-richikwidibira zvinodhaka "Simvastatin". Mirayiridzo dzokushandisa haafaniri kupa mushonga varwere vasina asvika makore gumi nemasere okuberekwa, vakadzi vane pamuviri uye vanaamai vechiduku achiyamwa. With hanya huru inofanira kushandisa izvi mapiritsi varwere chiropa chirwere, hypotension kana netsviyo. In chisingaperi udhakwa uye zvikuru cheitsvo kutora mushonga "Simvastatin" kunofanira chete kuva pasi zvokurapa achitarisirwa. Mukuwedzera, ndandanda hama contraindications anosanganisa wakawedzera uye ungaderedza skeletal tsandanyama matauriro.
Kusvikira zvingakonzerwa nemishonga kuti kushatiriswa zvinodhaka yaunodya "Simvastatin", chinhu chokutanga pano zvakafanira govera ngozi pfungwa nomuviri zvemwana asati, peripheral neuropathy, hypotension, myopathy, volchanochnopodobnogo urwere, rhabdomyolysis uye thrombocytopenia. Uyezve, pfari kunogona kuitika, dzungu, flatulence, kurasikirwa kudya, angioedema, mapundu, Flushing, urticaria, eosinophilia, photosensitivity, vasculitis, fivha, tsandanyama paresthesia, alopecia, uye kupererwa neropa.