Naiz (piritsi) - kudzidziswa Chinyorwa.

chipimo chemushonga fomu

Kugadzirira yakaitwa muna 3-zvinodhaka siyana - kuturika, dispersible mahwendefa uye kwakajairika. The kuturika ndiyo munhuwi dzinonakidza nepanomboratidza yellow ruvara uye zvikuru sevanhu kuravidza zvinodhaka ichi. The kuturika inogona redispersed nokubatana chinu.

Mahwendefa anogadzirwa anenge chena, pamwe zvishomanana yellowish tinge. Mahwendefa tenderera chimiro, biconcave, hukawanika ayo vaviri inotsvedzerera.

Hanayakanari sezvamunoita:

kuturika

Active fuma

• Nimesulide - 50 MG (5 ml kuturika)

Excipients:

• sorbitol
• shuga
• xanthan chemazino
• propyl
• methylparaben
• cucumber asidhi
• chihenge munuhwi
• Yellow dhayi WS
• glycerol
• polysorbate
• Yakanatswa mvura

dispersible mahwendefa

Active fuma

• Nimesulide - 50 MG (Table 1).

Excipients

• aspartame
• karusiyamu phosphate
• microcrystalline cellulose
• carboxymethyl starch
• zviyo starch
• talc
• magnesium stearate
• Colloidal nesilicon yakasviba
• chihenge munuhwi

mahwendefa

Active fuma

• Nimesulide - 100 MG (Table 1).

Excipients:

• magnesium stearate
• Karusiyamu rehydrogen Phosphate
• microcrystalline cellulose
• Anhydrous colloidal nesilicon
• zviyo starch
• Yavaibvisa starch glycolate
• Yakanatswa talc

The pharmacological zviito zvinodhaka

Pharmacological chiito chokuita zvikurukuru Hanayakanari - mapiritsi, mirayiridzo rine mashoko ose chipimo chemushonga siyana. The mushonga ari NSAID, rine ayo maumbirwo sulfonilidnuyu muzvikwata zvisina tsarukano. Nimesulide may chokuita FIs pamusoro Cox-2, saka kuti ane Anti-anogumbura uye marwadzo anokonzerwa, mukuwedzera, mushonga rine unonyaradza marwadzo anokonzerwa, asi zvishoma.

The mashandiro kuita zvinodhaka zvine chokuita kudzvinyirira pamusoro kwetunhu prostaglandins ari kuzvimba uye kudzvinyirira pamusoro paumbwe okisijeni radicals uye chinovhiringidza pakati myeloperoxidase kusunungurwa.

Pharmacokinetics

Hanayakanari zvakakwana wefodya kubva nemudumbu, kusvika kunonyanyisa kwayo muropa kare pashure 2 maawa. The mushonga ndiyo 99% mapuroteni akasungwa.

Kugadzirira nize - Mahwendefa muperekedzi iyo inotorwa kubva pamutemo manyuko, metabiliziruetsya ari chiropa uye yabudiswa muna weti, pamwe 98% of dose yakagamuchirwa ndiyo goho masikati.

umboo

• Rheumatic zvirwere kuti kuva kunze mekamudzira aka
• chemajoini
• Kuzvimba uye marwadzo pashure kuvhiyiwa
• Marwadzo anokonzerwa dysmenorrhea
• Nefivha uye marwadzo panguva rikwanise kuzvimba chokumusoro Airways

Side Migumisiro Hanayakanari

Mahwendefa, mirayiridzo izvo zvino, unogona kubereka divi-anokonzerwa siyana gadziriro uye nhengo:

Side Migumisiro chinodhaka, izvo chokuita zvomudumbu turakiti

• svoto
• chirungurira
• dumbu marwadzo
• ugare zvituru

Side Migumisiro chinodhaka, izvo chokuita nechepakati tsinga:

• nomusoro
• hope
• dzungu

Side Migumisiro chinodhaka, izvo chokuita neutachiona:

• erythema
• upundu
• urticaria

Other nemishonga:

• Chengetedzo mumuviri Urume
• oliguria
• bundu

Hanayakanari contraindications

Ko mazita contraindications umo Zvinokurudzirwa kudzivisa kutora zvinodhaka, uye kana zvakakodzera zvachose, chete mushure mekubvunza chiremba wako.

• Ropa kubva nemudumbu
• itsvo kutadza
• hepatic kukundikana
• Pregnancy uye lactation
• Peptic gastrointestinal chirwere

Drug kudyidzana nize

Mahwendefa, mirayiridzo kushandiswa asingasvavi kuguma kwakakwana uye nzwisisika mashoko ose zvinodhaka mukukurukurirana Pfungwa yaiva sezvinotevera: kwete yakarumbidza pamwe anotevera vamiririri - phenytoin, digoxin, chero diuretics, zvinodhaka lithium, anticoagulants, antihypertensive zvinodhaka, NSAIDs, methotrexate, cyclosporin .