"Paroxetine": mirayiridzo kushandiswa, wongororo. zvinodhaka analogues

Chii chinorehwa zvinodhaka "Paroxetine"? Mirayiridzo kushandiswa kwezvinodhaka zvichakurukurwa munyaya ino. Uyewo mariri iwe wava kuziva chero contra-zvairatidza uye anowanika kubva mishonga iyi, kana akanga chero marwadzo, mune ipi aripo uye kuti mushonga interacts nedzimwe zvinodhaka.

Zvinoumba, kavha uye chimiro zvinodhaka yokusunungurwa

Drug "Paroxetine" anoenderera mberi Sale muchimiro mapiritsi, film-zvemapuranga. Vane tenderera uye lenticular chimiro, ruvara chena, uye mukana munhu ine penyika.

The rinoita fuma runoonekwa nesu zvinoreva paroxetine hydrochloride hemihydrate. Uyewo, kuti mushonga waro sezvamunoita zvinotsigirwa zvinhu muchimiro colloidal nesilicon dioxide, microcrystalline cellulose, crospovidone, karusiyamu rehydrogen phosphate, copovidone, talc uye magnesium stearate.

Mahwendefa "Paroxetine" vari kutengeswa mhoni packs it zvezvimedu 10 iyo inoiswa munhu makadhibhokisi bhokisi.

The pharmacological zviito zvinodhaka

Chii chinodhaka "Paroxetine", iro analogues uchanzi zvishoma mberi? Inguva antidepressant. It is inhibitor pamusoro (zvokusarudza) kweserotonin reuptake uropi Tutsinga tunofambisa mashoko utwu. Izvi ndizvo anosarudza zvayo Anti-depressive zvinokonzerwa uye efficacy mukurapa mokutya rebipolar uye nyanyisa-muropa zvirwere.

Viewed Zivisa medicament ane pasi kwazvo sungano nokuda α2-, α1- uye β-adrenoreceptors uyewo mamita-holinoretseptorami, dopamine, 5HT1-kufanana, 5HT2-zvakadai uye histamine H1-receptors.

Ita psychomotor mabasa anotyora zvinodhaka "Paroxetine"? Reviews vanachiremba vanoti mushonga haana zvainoita dzevanhu psyche okusafarira. Uyezve, hazvingaiti potentiate ari depressant kukanganiswa panyaya iyi pamusoro psychomotor mabasa.

Zvichipomerwa vanotsvakurudza vanozivikanwa chinhu antidepressant kwakadaro simba simba ehupfumi chete kana chinotarisirwa pana dosages kupfuura avo inodiwa chinovhiringidza kweserotonin reuptake. Hatigoni kutaura kuti zvinodhaka izvi haakonzeri kuchinja rinokosha BP yomuropa, eeg uye kwemwoyo.

The pharmacokinetics ane zano wezvokurapa

zvinodhaka "Paroxetine" sezvo kunyura? Mirayiridzo yokushandisa, vanachiremba chaivo vanoti kuti pashure nomumukanwa kwokubatsira yezviri fuma wefodya kubva zvomudumbu turakiti uye rinoita kubudikidza chiropa.

The mira Kuwanda medicament muropa kubudirira kuburikidza mavhiki 1-1.7 pashure mharuro kurapika. The kushingaira wemafuta zvinodhaka riri munzvimbo yakakura akaparadzirwa munyama. Muchiitiko chino, zviri muzana imwe chete inowanikwa plasma. Kukurukurirana pamwe mapuroteni ari Unorudzi 95%.

Antidepressant rinoita ari chiropa. Somugumisiro, basa metabolites vari aumba. Vakakurumidza zvachose muviri, uye kuva pasi pharmacological basa uye vasina zvainoita kuchirapa zvinokonzerwa zvinodhaka.

zvinodhaka "Paroxetine" sezvo akaratidza? Ona, vemishonga ratings vanoti vanenge 64% yezviri fuma iri pauri pamwe weti, apo dzasara 36% - ari ura (mu bile).

The pharmacokinetics zvinodhaka iri rinokosha zvekuchipatara ezvinhu

Kuwanda vanoshingaira fuma iri plasma kunowedzera kutyora itsvo uye chiropa uyewo vakwegura.

Zvairatidza kuti kushandisa zano wezvokurapa

Mune zvimwe zviitiko, varwere vari ushandiswe antidepressant "Paroxetine"? pamusoro pokushandisa chishandiso gwaro rine zvinotevera mazita kuverengwa:

• chero mhando mwoyo, kusanganisira zvikuru endogenous, reactive, uye pamwe nokufunganya;
• kutya zvinetso, kusanganisira agoraphobia;
• nyanyisa-muropa nyonganyonga (OCD kana rakapfupikiswa);
• generalized kufunganya nyonganyonga;
• evanhu mwoyo chirwere, kana inonzi evanhu phobia.

Contraindications kuti kushandisa zano wezvokurapa

Mune zvimwe zviitiko, hapana nyaya haagoni kushandiswa varwere antidepressant "Paroxetine"? pamusoro pokushandisa chishandiso gwaro chinosanganisira zvinotevera mazita contraindications:

• kusagadzikana pfari;
• pamunhu yaizoshanda panguva kushandiswa monoamine oxidase FIs, uyewo imwe nguva-vhiki mbiri pashure kurega kwavo;
• chevana zera;
• pokuva nezamu;
• Hypersensitivity kuti mushonga zvinoriumba izvozvo;
• paanenge achiyamwa.

Shandisa nokungwarira zvakanyanyisa

In chii Muzviitiko zvinofanira kudzorwa yaunodya pamusoro antidepressant "Paroxetine"? Mirayiridzo dzokushandisa inotaura kuti gadziriro iyi chinotarisirwa nokungwaririra varwere vane chiropa kukundikana, angled-kuvhara yemaziso, renal kukundikana, zvokudarikidza, prostatic hyperplasia isiri yekenza, convulsive inoti, cardiac zvirwere, netsviyo. Uyezve, mashoko pamunhu yaizoshanda panguva kushandiswa mishonga ndonda uye cardioversion, uyewo mishonga kuti zvinowedzera mukana ropa. Tinofanira kubhadhara pfungwa pamberi zvinokonzera ngozi ropa zvinetso uye inosimudzira kwakadaro chirwere inoti.

Antidepressant "Paroxetine": sei kutora mushonga?

Tiri kufunga mushonga chinobviswa nomuromo kamwe pazuva (mangwanani) panguva chisvusvuro. Mahwendefa zvinofanira kumedzwa yose, kushambidzwa pasi pamwe pachena mvura.

Mumazana vhiki nhatu pashure pakutanga varapwe chipimo chemushonga iri kugadziridzwa nomumwe. Zvinonzi dzakwidzwa kugadziridzwa (kana zvakakodzera).

Munguva kwenguva refu mwoyo yakarumbidza chitsama medicament ndiyo 20 MG kamwe pazuva. Kana waida kuti dose iri zvishoma nezvishoma yakawedzera 10 MG. Max akagamuchira mushonga haafaniri kupfuudza 50 MG.

For nyanyisa muropa nyonganyonga kutanga dose ane antidepressant ndiyo 20 MG pazuva. Zvadaro, anowedzera kuti 10 MG. Zvavakabvumirana avhareji daily dose nokuti kutsaudzira yakadaro 40 MG. In chenjera faniro unogona ngazviwedzerwe 60 MG.

Kana murwere ane kunyonganiswa chirwere, unogona pakutanga kutora kusvika 10 MG zvinodhaka pazuva. Kuderedza zvaibvira ngozi vanetseka zviratidzo vari Zvakazoitwa dose zvinodhaka riri yakawedzera 10 MG. Paavhareji, kana akadaro kutsaudzira unogamuchirwa kushandisa 40 MG "paroxetine" mumaawa, kufadza nhamba - 50 MG.

Kana munzanga phobia kana mumagariro kufunganya zvinetso medicament kwokutanga vhoriyamu haafaniri kupfuudza 20 MG pazuva. Kana pashure kurapa kwakadaro zvinozoita haina kubudirira, 2 ipapo shomanana dose iri kuwedzera zvishoma nezvishoma kuti vaifanira, kuti zviri 50 MG pazuva.

In generalized mwoyo chirwere kuchirapa uye kutanga Vhoriyamu medicament ndiyo MG 20 pazuva

Kana murwere nechirwere chiropa kana itsvo kukundikana, zvavakabvumirana dose inofanira kuva 20 MG pazuva.

vanhu vakwegura rimwe zuva unogona ipere hapana anopfuura 40 MG ari kurapwa.

Kuitira kudzivirira ucharwadziwa kurega kutora mushonga inokurudzirwa zvishoma nezvishoma.

zviitiko ovhadhozi

Pane zviitiko ovhadhozi pamwe antidepressants akadai "Paroxetine", "Fluoxetine"? Nyanzvi dzinoti kushandiswa vakawanda mapiritsi chaizvoizvo kukanganisa muviri womunhu. Murwere ruzivo kuda kurutsa, muromo yakaoma, sinus tachycardia, kurutsa, kugwinha, tremor, bradycardia, mydriasis, nokusagadzikana, kushatirwa, vangadikitira, nystagmus, wakawedzera BP, somnolence, uye nodal mutinhimira.

In kumbonyanya zvisingawanzoitiki zviitiko apo kushandisa mushonga nedzimwe zvinodhaka psychotropic, uye doro kunogona comatose murwere kusiyana ari chiratidzo pamusoro ECG. In chakakomba ovhadhozi, murwere ari kweserotonin chirwere uye rhabdomyolysis.

Zvokuita mumamiriro ezvinhu akadaro? Kana zvinodhaka ovhadhozi "Paroxetine" vanofanira kuva gastric lavage, uye kutora kusashanda kabhoni. Kana zvakakodzera, symptomatic kurapwa.

nemishonga

Ndezvipi kurutivi migumisiro mishonga inogona kukonzera "Paroxetine"? Reviews vanachiremba vanoti chokushandisa ichi zvechokwadi kunobatsira kukura nenjodzi. Izvi zvinosanganisira zvinotevera ezvinhu uye zvirwere:

• Pamusoro chikamu nechepakati tsinga uye peripheral tsinga: zvokudarikidza, hope, kuvhiringidzika, tremor, kweserotonin chirwere, kurukutika, aone zvinhu zvisipo, kushaya hope, kutya, dzungu, depersonalization, kurukutika, vhunduka, nezvipusha, nokusagadzikana, kukanganwa, extrapyramidal wenyonganyonga, myoclonus, kuzvidya mwoyo.
• Zvetsandanyama nemapfupa maitiro: tsandanyama simba, arthralgia, myopathy uye myalgia.
• Pfungwa: Blurred uye madzerere yose.
• Urinary maitiro: kuita weti kakawanda kana Urinary chengetedzo.
• Zvomudumbu turakiti: zvakawedzera kana ungaderedza kudya, hepatitis, kuravira shanduko, muromo yakaoma, kuda kurutsa, manyoka, kurutsa, uye kupatira.
• Dzokubereka nadzo: anorgasmia, pabonde dysfunction, hyperprolactinemia kana galactorrhea, kusabetsera uye ejaculation zvirwere.
• Kumwoyo: orthostatic hypotension.
• Chisimbwa: kuvaviwa, mapundu, angioedema, uye urticaria, ecchymosis.
• Other variations: rhinitis, vangadikitira, kukodzera secretion pamusoro antidiuretic kemikari, hyponatremia.

Kudyidzana nevamwe vanachiremba nzira

Kushandiswa mawa pakati antacids hakurevi kukanganisa pharmacokinetic parameters uye Absorção de Água zvinodhaka "Paroxetine".

Contraindicated mumwe-nguva kushandisa mari pamberi pedu pamwe Mao FIs.

Mawa kugamuchirwa medicament "paroxetine" zvinodhaka kuti tunodzivisa chiropa makemikari, zvinoda achideredza wokutanga dose.

Antidepressant Kurebesa nekudeura ropa pakanyorwa imwe-nguva kushandisa "kuti warfarin."

Mawa kushandiswa medicament "paroxetine" pamwe tricyclic antidepressants, aspirin, atypical neuroleptics, NSAIDs uye zvinoreva phenothiazine dzakatevedzana kunoita ropa pakugwamba rikurumidze.

Mawa Kutarisirwa pamwe serotonergic nevasori (akadai se "tramadol" uye "sumatriptan") kungaita nyore kuti kunowedzera serotonergic migumisiro.

Zvakakosha kuyeuka!

Kuti tidzivise kukura munhu neuroleptic syndrome (nyanyisa), mushonga ne yokunyanyisa nokungwaririra "Paroxetine" ushandiswe varwere vari antipsychotics.

vanhu Older pamusoro pakanyorwa zvinodhaka zvingamuka hyponatremia.

Kana zviratidzo pfari uye zvokudarikidza antidepressant kurapa wokutanga anomiswa.

Muvhiki kwokurapa ne "paroxetine" wokutanga zvinoda kungwarira kuongorora murwere nokuda zvichibvira kuzviuraya.

Panguva mushonga vanofanira kurega doro nokuda kwavo kunowedzera muchetura kushanda.

chiremba kushandiswa

Drug "Paroxetine" haungopiwi vana, sezvo ayo kuchengeteka uye efficacy pakurapa varwere vari muboka iri havana dzakatangwa.

Antidepressant "Paroxetine": dzomuzana

The mushonga inogona kutsiviwa ne "Paroxetine"? Zvinofanira kucherechedzwa kuti mishonga iyi, pane wandei dzomuzana shoma. Pakati pavo, zvingava zvinokosha kuratidza zvinotevera zvinodhaka: "Reksetin", "Adepress", "pliz", "Apo-Paroxetine", "Aktaparoksetin", "Paxil", "sertraline", paroxetine hydrochloride hemihydrate, "" Sirestill "uye zvichingodaro.

Kutenga zvose mishonga izvi panguva chemishonga, iwe unogona chete mushonga.

Reviews kuti medicament

Drug "Paroxetine" anezvakawanda zvakavhenganiswa nezvaro, zvose kubva nyanzvi uye kubva varwere. Kudivi rimwe, iri anorumbidzwa nokuda chii hunoita kuti nokukurumidza kubviswa chero mhando mwoyo (kusanganisira zvakakomba endogenous, reactive, uye pamwe nokufunganya), uyewo kutya, nyanyisa-muropa, generalized uye zvemagariro kufunganya nyonganyonga. Kune vamwe - varwere vakawanda vanoti pakarepo mushure mushonga vanokurukura zvikuru vakawanda nenjodzi. Somugumisiro, vanhu vakatova kumisa kurapwa.

Kazhinji, nyanzvi dzinoti "Paroxetine" - ichi zvinobatsira chaizvo uye vakarongeka zvinodhaka kuzvigona basa basa nayo. Zvisinei, izvozvo zvinogona kushandiswa chete chahwo chinangwa nyanzvi.