"Passazhiks": mirayiridzo kushandiswa. "Passazhiks": zvairatidza kuti kushandiswa, dzomuzana chaiwo

Kurutsa dzepanguva akadana kuputika muromo (dzimwe nguva achishandisa mhino), zviri mudumbu kana duodenum 12. Fani iyi imhaka zvinoderedza venhau tsandanyama.

Panguva kurutsa kuti goho mugove mudumbu yakavharwa uye muviri wake zvachose vagadzikana. In wokupinda ichi kuzarurwa, uye kuwedzera yegurokuro uye kunanzvana mhango.

All rakarondedzera dzepanguva chiito inotongwa kurutsa centre, riri munzvimbo medulla oblongata. mamiriro uyu munhu anogona kuonekwa zvinotapuriranwa, chepfu, kuunganidza zvinokachidza zviri muropa, pamwe peritoneal nokushatiriswa maronda, gastritis, vakadzi vane pamuviri uye nevamwe.

Episodic kurutsa haina achiperekedzwa ropa, uye asingauyi vanotyisidzira upenyu murwere. Asi kana izvi inodzokororwa kakawanda, zvinogona kutungamirira zvakakomba. Izvi zvinosanganisira kupera mvura mumuviri uye electrolyte kusaenzana zvinogona kutungamirira kurufu. Ndokusaka zvakakosha kuona chiremba kana kwenguva nenguva kurutsa. Also kunodiwa kutora mishonga chaiyo, izvo zvinobatsira kuti vanhu vasaziva dzepanguva.

Chinonyanya dzakakurumbira antiemetics anosanganisira mushonga akadai "Passazhiks". Zvairatidza kuti kushandiswa kwezvinodhaka, uye mirayiridzo zvichakurukurwa pazasi.

Release chimiro, akafanana uye chiputiriso

In chii chimiro aripo zvinodhaka "Passazhiks"? Consumer ongororo kukuzivisai kuti zvingagadziriswa chakatengeswa muchimiro chewable mahwendefa. Ivo vari kugara mu Maronda akasiyana uye makadhibhokisi bhokisi, ukuwo.

The rinoita chirungiso vaiona zvinodhaka anoita domperidone. Ebetsero zvinhu zvinoshandiswa vari aspartame, xylitol, lactitol, magnesium stearate uye menthol.

pharmacological unhu

Mirayiridzo kushandiswa ( "Passazhiks" rinofanira kushandiswa bedzi mushonga) rinoshuma kuti pomutumwa anoonekwa ane Anti-emetic zvinodhaka. It is antagonist nechepakati dopamine receptors.

Active medicament anokwanisa kuwedzera ya peristaltic sunga iri antrum mudumbu uye duodenum 12. Rinotaurawo Inowedzera kuti Kuburitswa mu zviri zviri zvomudumbu turakiti (panguva deceleration acho), anobvisa kuda kurutsa uye kurutsa, kunowedzera mataurire esophageal sphincter (nechepazasi chikamu).

Tinofanira kuonawo kuti domperidone nani havaratidzi chinopinda kuti ropa-uropi nokuidzivirira. Ndokusaka kushandiswa mishonga iyi kashoma achiperekedzwa extrapyramidal siyana.

Zvinofanira kucherechedzwa kuti domperidone anokwanisa kukurudzira prolactin kusunungurwa kubva pituitary.

Action (antiemetic) zvinodhaka izvi nokuda pokudzora mubatanidzwa gastrokinetic uye dopamine daka ari chemoreceptor rukungiso wongoramba. Zvinofanira akati kuti nefuma une maturo wakakomba pamusoro gastric secretion.

kinetic ehupfumi

Ndezvipi yokusafa kinetic parameters medicament "Passazhiks"? Mirayiridzo dzokushandisa chinoratidza kuti pashure kutora chewable piritsi, zvinoshingaira chirungiso riri zvikuru nokukurumidza wefodya unopinda muropa.

Domperidone ane pasi bioavailability (vanenge 15%). kunonyanyisa wevasungwa Its iri kuchengetwa pashure maminitsi 65.

Neb gastric acidity anogona kuderedza zvinodhaka Absorção de Água.

Maererano nenyanzvi, domperidone iri rinoparadzirwa mune nyama siyana. Kana uropi, wevasungwa zvinodhaka mairi iri duku. Kukurukura mapuroteni eplasma anenge 92-93%.

Kuonawo kuti zvinodhaka "Passazhiks" (Mahwendefa) rinoita muna chiropa uye dumbu rusvingo. Output nayo nomukombiyuta ura (anenge 66%) neitsvo (vanenge 33%).

The hafu upenyu zvinodhaka ndiko maawa 7-8. In zvakakomba renal kukundikana akapiwa chinguva iri miforo.

umboo

Viewed medicament nachiremba svoto uye kurutsa-siyana mavambo, kusanganisira Organic uye dzichipfekeka zvirwere, nemwaranzi marapirwo uye chirwere. Uyewo, chokushandisa ichi inogona kunzi ari toxemia, achitora morphine, kudya kutyorwa, kushandiswa "Levodopa", "Apomorphine" uye "Bromocriptine".

Zvii zvimwe zviitiko, mishonga angashandiswa "Passazhiks"? Mirayiridzo dzokushandisa inoratidza kuti mushonga uyu rinowanzoshandiswa ushandiswe panguva atony ari nemudumbu (kusanganisira postoperative), hiccups, radiopaque uye endoscopic zvomudumbu turakiti zvidzidzo. Also vaiona mushonga kunodiwa kuti mhanyisa peristalsis mune chirwere dzokuvhiya, dyspeptic zvirwere yomuka somugumisiro kunonoka gastric Kuburitswa mu, esophagitis, uye gastroesophageal reflux.

Mahwendefa "Passazhiks", zvinoratidza zviri kukurukurwa pamusoro zvakanaka unooneka sokuti nokuzara mudumbu, flatulence, bloating manyawi, gastralgia, chirungurira uye belching.

Contraindications

Kana uchifanira kushandisa piritsi "Passazhiks"? Mirayiridzo yokushandisa, wongororo akashuma zvinotevera contraindications zvinodhaka pasi kukurukurwa:

• hypersensitivity;
• Vana vari pasi pemakore 5 years, uyewo vana yairema kusvika 20 makirogiramu;
• prolactinoma;
• fenilketonuriyaiya.

Zvinofanira kucherechedzwa kuti mudziyo hakuratidzwi kana injini kweiyi mudumbu kunogona kuva nengozi (nokuti gastrointestinal ropa, perforation, kana zvokuimba mhingaidzo).

Chenjerera zvinodhaka izvi zvinogona kushandiswa varwere renal kana hepatic insufficiency panguva yepamuviri uye lactation.

Mahwendefa "Passazhiks": mirayiridzo kushandiswa

Chewable mahwendefa "Passazhiks" varumbidzwa kutora pamusoro ¼ awa vasati vachidya.

In chisingaperi dyspepsia vakuru kugadza 10 MG dose (1 piritsi) katatu pazuva. Kana zvakakodzera, mishonga inogona kutorwa panguva yokurara.

Vana vakuru 5 years, chokushandisa ichi kupa 2,5 MG pa 10 kg asi kurema muviri katatu pazuva uye, kana zvakakodzera, ndisati ndarara.

In subacute kana chakasimba inoti (svoto uye kurutsa) raitongwa varwere vakura 20 MG kanokwana rimwe zuva, uye pamberi yokurara. Vana vakuru 5 makore inokurudzirwa kutora 5 MG zvinodhaka pa 10 kg asi kurema muviri kanokwana rimwe zuva uye panguva yokurara.

In renal kukundikana zvinoda chipimo chemushonga kugadziridzwa multiplicity kugamuchira hapana zvinopfuura 1-2 nguva masikati.

The kunonyanyisa chipimo chemushonga kurapwa pazuva nokuda nevakura 80 MG (kureva 8 mahwendefa). Panyaya vana, hazvifaniri kuva kupfuura 10 MG pa 10 makirogiramu kurema mwana.

nemishonga

kana nenjodzi chewable mapiritsi "Passazhiks" kukonzera? Nyanzvi Guest vanoti chokushandisa ichi kunogona kukonzera nemigumisiro dziri:

• zvinopfuura intestinal chinyamunhari chinorwadza;
• extrapyramidal Migumisiro;
• kuwedzera prolactin wevasungwa munguva plasma;
• galactorrhea, gynecomastia uye dysmenorrhea;
• mapundu, uye urticaria.

Zviratidzo ovhadhozi

Ndezvipi zviratidzo ovhadhozi anogona kukonzera mishonga "Passazhiks"? Manual rinoti akadaro mananara zvinosanganisira hope, nekuvhiri- ngika uye extrapyramidal siyana.

Zvinokurudzirwa kuti kutora neactivated charcoal uye bvunza chiremba kunorapwa mamiriro ezvinhu akadaro.

Kudyidzana nevamwe zvinodhaka

Mawa kurapwa nemishonga "Passazhiks" pamwe anticholinergics anogona neutralize mugumisiro wokutanga.

The akabatana antacids kunoderedza bioavailability kwayo.

Kana zvabatanidzwa uye domperidone medicaments zvichivhiringidza ari isozyme CYP3A4 (semuenzaniso, asingaurayiwi macrolides, azole antifungals boka, imwe antidepressant "Nefazodone" HIV runovharidzira mamwe FIs), murwere anogona kuona kuwedzera wevasungwa yezviri fuma muropa.

mishonga Viewed haadi kuchinja wevasungwa kuti digoxin mu yeplasma uye paracetamol. Hazvina kunze kuti kukanganisa Absorção de Água mishonga (panguva aishanda nomuromo) pamwe kunonoka kusunungurwa vanoshingaira chirungiso kana enteric-Coated.

Achiyamwa uye pamuviri

Drug "Passazhiks" rambidzwa kutora panguva pamuviri.

Panguva naka pabonde domperidone wevasungwa munguva mukaka kakapetwa zvina kudzika kupfuura plasma. Hazvina kuzivikanwa kuti ichi ane inokanganisa vana. Naizvozvo, kana zvakakodzera, kushandiswa kwezvinodhaka panguva lactation achiyamwa anofanira vakarega.

Mahwendefa "Passazhiks": dzomuzana uye mutengo

Mari mari iri pamusoro 220-360 rubles. Kana akakumbira, kuti antiemetic zvinodhaka inogona kutsiviwa neimwe mishonga yakadai "Motilium" pamusoro, "Domstal", "Kinedril", "Avioplant", "Doprokin-C", "Diskineton", "Emeset", "Motinol" uye saizvozvo. d.

Zvinofanira akayeuka kuti vose mari idzi dzingava maitiro avo. Naizvozvo, kuzvishandisa panzvimbo "Passazhiksa" kunofanira chete pashure zano chiremba.

Reviews kugadzirira

Vazhinji varwere kubatwa mishonga iri mubvunzo, kutaura pamusoro wayo yakakwirira kunyatsoshanda. Maererano vanoshandisa, ichi chinomirira akanaka nokukurumidza kubvisa kunzwa svoto uye chinonditadzisa kurutsa.

Zvinofanira kucherechedzwa kuti mishonga iyi inogona kubatwa zvimwe zviratidzo. Somuenzaniso, rinowanzoshandiswa panguva uremu mudumbu kana abdominal distention. Panyaya iyi, mahwendefa chewable varumbidze kutora rimwe panguva katatu pazuva kwemazuva mashanu.

The chikuru zvipi kugadzirira "Passazhiks" rinoreva marwadzo yomuka pamusoro mabiko wayo, uyewo kuvapo contraindications siyana.