Product "Onbrez Brizhaler": mirayiridzo kushandiswa, akafanana, analogues, dose

Nokuti kurapa echirwere obstructive pulmonary chirwere hunhu yakazokudziridzwa uye vakaedzwa harmlessness ari itsva zvinodhaka "Onbrez Brizhaler 'mapikicha dzinoturwa pazasi.

General unhu

The mushonga kugadzirwa nenzira kambani Swiss AG "Novartis". Pane dosages zviviri (nenguva 0,300 MG uye 0,150 MG) medicament "Onbrez Brizhaler". Description rekugadzirira ndozvavava sechinhu chena upfu pamusoro inhalation, icho mumapepa mu capsules.

It sympathomimetic inhalation mumiririri kuti kubata obstructive zvirwere kufema hurongwa. Ndezvenguva beta2-agonists anyatsosarudza.

In zvakaoma gelatin capsules wechitatu yepamusoro dose saizi ine segirazi pasina ruvara chivharo uye hunde. Pamusoro pendi dema rinoshandiswa Logo boka, riri pazasi nokurohwa nhema pasi Kamudzira rine rokuti «IDL 150", riri pamusoro nokurohwa vatema.

In zvakaoma gelatin capsules rechitatu saizi dose duku rine segirazi pasina ruvara chivharo uye hunde. On yokumusoro hafu zvemapuranga Logo rebhuruu pendi boka, riri pazasi yebhuruu bhendi, uye rezasi chikamu Kamudzira rine yebhuruu chitaridzi «IDL 300", riri pamusoro rwebhuruu mutsetse.

mamiriro

Mumwe Kamudzira rine indacaterol maleate mune imwe mari 0,194 MG paminiti dose uye panguva 0,389 MG vakawanda chipimo chemushonga. The upiyona zvinoriumba rakashandiswa muchimiro mukaka shuga excipient, zvinogona kuchinja mukanyiwa mukati.

Complex ane Kamudzira goko "Onbrez Brizhaler" sezvamunoita, uye mirayiridzo chinosanganisira mazita ose zvokubikisa. The bemhapemha achiumbwa panguva dose pamusoro shellac, gelatin, simbi oxide uye ferric dema, mvura yakachena, propylene glycol.

yepamusoro chipimo chemushonga Kamudzira goko rine zvinhu siyanei. The bemhapemha achiumbwa pamwe shellac, gelatin, simbi oxide uye ferric dema wakachena aqueous unosvikirwa, propylene glycol, Brilliant ruvara rwebhuruu, titanium dioxide.

mashandiro pamusoro Action

Zvinodhaka "Onbrez brizhaler" User Application anotsanangura mugumisiro yezviri chirungiso indacaterol iyo kana makemikari ligand inowedzera mhinduro adrenozavisimyh beta2-receptors. Ichi pharmacological nezvinozoitika nokuda activation ari adenylcyclase enzayemu mukati masero, panguva iyo Inowedzera adenosine kuchinja mune samolecular muchimiro cyclic 3 ', 5'-adenosine monophosphate.

Kuwedzera rokupedzisira zvinoriumba ndiye kwakaderera tsandanyama ari Árbol pachaenzaniswa. Indacaterol rinoratidza mukuru basa chokuita beta2-receptors. selectivity Its zvakafanana zvinoitwa formoterol.

Capsules "Onbrez Brizhaler" kana inhaled zviratidzwa bronchodilatory dzomunharaunda chaizvoizvo ari kufema ino.

basa rayo riri interconnected pamwe akaderedza zvemapapu distension masvingo vane mwero kana zvakakomba obstructive chirwere mamiriro ari kunofambira mberi uye simba mamiriro.

Kamwe pazuva Kutarisirwa zvinotisvitsa chenguva zvinokosha kuita kuvandudzika ari kufema zvomukati. The rinoita fuma anotanga kuita nokukurumidza uye mumaminitsi 10 chinoratidza basa. Izvi zvakawanda zvinobudirira kupfuura nezvaizoitwa salbutamol ari dose pamusoro 0,200 MG kana salmeterol / fluticasone ari chipimo chemushonga pamusoro 0.050 / 0.500 MG. The kunonyanyisa basa indacaterol zvinogoneka pashure maawa 3-4 chete kubva yaitonga kubudikidza inhalation. Morning kana manheru kushandiswa kwezvinodhaka haachinji ayo bronchodilator maturo.

kuti anobata

Medicine "Onbrez Brizhaler" mirayiridzo Chinyorwa rinokurudzira kushandisa yokuzvigadzirisa kurapa pakati obstructive kuchinja bronchodilation turakiti kufema vari varwere pulmonary obstructive chisingaperi pezvakaita chirwere. Somugumisiro chirwere chakadai kurambidzwa mhepo aibuda zvinoderedza uwandu inhaled mhepo, kuva kupfupika mweya. The kutanga pavaipfuura chirwere chinogona chinozivikanwa chikosoro, sputum, dyspnea, uye hoarseness panguva simba mitoro.

How kushandisa

On mishonga "Onbrez Brizhaler" chipimo chemushonga uye nokutarisira kuti vakura kupendwa mirayiridzo. Kazhinji, vanachiremba vanoti zuva mari imwe inhalation zviri chimwe Kamudzira chipimo chemushonga kuti 0,150 MG. The nzira yakanga raitwa achishandisa inhaler kana brizhalera, ndizvo sechinhu adjunct kuti zvinodhaka. The chipimo chemushonga inogona yakawedzera chete nachiremba agadzwa.

In zvakakomba obstructive zvemapapu inhalation rinoitwa rimwe Kamudzira rimwe zuva ine dose pamusoro 0,300 MG. The nzira kwainge kwave kushandisa brizhalera. Maximum daily kwazvo pamusoro medicament kwaenzaniswa 0,300 MG.

Mishonga "Onbrez Brizhaler" kurayira Chinyorwa haibatanidzi amboshandurirwa chipimo chemushonga zvinodiwa varwere vakwegura. Inhalation hakusi akakodzera vana, vakanga vari basa chete pashure pemakore 18.

Kana maperembudzi pamwe kukundikana chiropa uye itsvo basa iri nepakati chimiro, chipimo chemushonga kugadziridzwa hauna kuitwa. With simba kutyorwa zviremera dzataurwa pamusoro apa regai kuitisa nemishonga mishonga.

Nokuti zvinodhaka "Onbrez Brizhaler" sei kushandisa wakaderedzwa chete inhalation brizhalerom chete yakasimba. Kamudzira mushonga hakusi akakodzera pakuparadza. Zvinofanira kushandiswa imwe nguva zuva nezuva. Kana paiva yokumbozorora kurapwa, haizopereri Kutarisirwa rinoitwa mu zvinotevera yakatarwa maawa zuva.

In mumwe rongedza idzidziso "Onbrez Brizhaler" midzi mudziyo nokuda inhalation mabhuku pepa uye dzine capsules pamwe weupfu mukati. The mushonga inopiwa kutaura, nechidzitiro, muvharo, nechigadziko uye bhatani lancing mudziyo.

Asati kuchinja ari inhaler pakavha chinobviswa. Kuvhura mudziyo anochengeta yakaderera chikamu chacho, uye ipapo vakatsauka nenzira mutauri.

Kubva pasuru atore mumwe Kamudzira nemaoko akaoma. Zvadaro akaiswa inhaler, akagara kune akasarudzwa nzvimbo. Regai kuisa mushonga mukati mutauri. Kuvhara mudziyo aine kombiyuta richinzwika.

Danho rinotevera richava kubaya yacho Kamudzira. Kuti izvi zvidaro, panzvimbo vertically vanopedza bundu Nemutengo kamwe pridavlivaniya mabhatani zviviri kuboora. Kazhinji, anzwike kurira schelchkoobrazny chinoratidza ponji Kamudzira unhani. Zvadaro achizviendesa mabhatani maviri inhaler mudziyo.

The mudziyo anonzi vakagadzirira bata uye kunogona kushandiswa. Pakutanga chikumbiro usati mutauri mumuromo mako, murwere anofema zvakadzika. Zvadaro anoisa kumicheto mumiromo, vakabata nayo zvakasimba vakarumanisa muromo. Brizhaler bata imwe yepamusoro richiripo uye kuitisa kukurumidza, yunifomu inhalation mhepo zvakadzama. Usabata Hardware bhatani kuti kuboora.

Pakuita maitiro evanhu akanzwa kurira, izvo yaunganidzwa kutenderera ari goko uye ipapo spraying zviri. Murwere ane inotapira kuravira mumuromo. Pasina kutsvakwa okuteerera chiratidzo zvinoda zvokudhinda inhaler kuedza munhu Kamudzira. Zvinokwanisika mumigwagwa yakawandisa motokari panguva nzvimbo pakusuma. Kana akatadza, ari Kamudzira chinobviswa tichibatsirwa chiedza taps on chikwata chawo. Hazvifaniri kuzodzosera wokudhinda kurutivi mabhatani. Apo vakawanda mukakuvadza Kamudzira vari dzichakoromorwa.

Panguva inhalation kungaita maitiro inzwi, ari mamiriro ichi murwere rinei mweya wake nokuda nguva inodiwa kudhonza anotaura akamirira dzaiita zvokutaurwa mhango. Chete ipapo patinofemera kunze mhepo. Izvi kudzivisa hachifadzi manyawi. Zvinonzi rambidzwa kuvhuvhuta kupinda mudziyo chubhu.

Kuongorora Kuwanikwa upfu mukati Kamudzira, mumwe anofanira kusimudza muvharo uye tarisa mumba inhaler. Kana akaona kuti Kamudzira mukati yakawanda, ipapo kuvhara kweguyo vadzokorora pamusoro matanho ose kuigadzira kuti evanhu. The Kamudzira rinocheneswa chose, kunyorwa kana maviri majekiseni nemishonga.

Inhalation kungakonzera jeko chikosoro. Chikonzero ichi ndiko kuwana wenguva dose kuti medicament. Dzimwe nguva zvinogona rova shoma upfu kubva Kamudzira iri nemumuromo mhango. Both kutyorwa hakufaniri nechikonzero chokunetseka.

Mushure inhalation murwere unofanira kuita mudziyo yokutanga, ichi vanoramba itaure chinhu Kamudzira goko kubviswa uye kuraswa nayo. Pipe ari ipapo kutura kuvhara muromo uye muvharo. Musarasa risina Kamudzira mukati huchashandiswa, sukurudza uye kuruka nayo.

With kavha mutsva havafaniri kushandisa yekare inhaler. Yokuchengetera kavha mudziyo uye ndiyo chete akakodzera Maronda akasiyana nzvimbo yakaoma.

On mushonga "Onbrez Brizhaler" Chinyorwa anokurudzira kuchengeta zvinyorwa manipulations kushandisa pakarenda mavanga, iro rinoshandiswa romukati pechiso rongedza. Kana vanhu zvizere uchayeuka kuti zvakakosha kubata inotevera inhalation.

For pavhiki kuchenesa mudziyo anofanira kupukuta pemvura wokunze uye rwomukati kufa yakachena, jira yakaoma. Usashandisa nemvura rokuchenesa. nhengo dzose inhaler inofanira rakaoma.

Features kurapwa

Mishonga "Onbrez Brizhaler" kurayira Chinyorwa harina kurumbidza kushandiswa mune varwere asima. Izvi zvinotsanangurwa maererano kushaya mashoko kuti zvaizoratidza kuti efficacy uye kuchengeteka chourongwa vanhu vakadaro.

Implementation angaperekedzwa inhalation vawedzere nehanya. Kana mukawana sema pezvakaitwa chokuita kufema akaoma kana kumedza, kuzvimba rurimi, miromo, uye chiso musoro, kunayisa muchimiro urticaria, kurapwa anofanira kuraswa uye rinopikisa zviito.

mishonga Inhalation anogona kutsamwisa bronchospasm gangaidzo mhando, akatakura ngozi upenyu murwere. Chero zviratidzo kukurumidza chikonzero Kudzimwa kurapwa uye kushandisa mishonga kubvisa kwacho.

Drug "Onbrez Brizhaler" anokwanisa mutoro chirwere, iyo Ndokusaka harishandiswi se chimbi matanho ari tanga rikwanise bronchospasm. Kana murwere akaramba achitowedzera kurwara ne mhingaidzo kuti mapapu pamusana inhalation zvokurapa, ipapo kuongorora murwere ezvinhu utano uye nzira kurapwa. Kwazvo kufadza zuva chipimo chemushonga ndechokungoti isingagamuchiriki.

Kana kuva zvikuru kurwisa (obstructive uye asthmatic), murwere kunoda rokukurumidzira muchipatara uye nokumutswa. Ndichibvunza kurapa vanofanira kutanga nokukurumidza sezvinobvira. Nokuti mushonga kurapwa nzira epinephrine, corticosteroids, aminophylline.

The chinodhaka inhaled pamwe zvavakabvumirana dosing kazhinji haakonzeri chinokosha chiito kumwoyo, mugumisiro wayo akafanana zvinhu kukonzera rudaviro adrenozavisimyh beta2-receptors. Very nokungwarira evanhu yaifanira kuti vanhu vane zvirwere myocardium uye ropa midziyo, kusanganisira mhando coronary insufficiency, cardiac mutinhimira shandurudzo, uye BP, convulsive pfari hunhu uye thyrotoxicosis. Kungwarira kunodiwa, uye kana vasiri fanana Achipindura kufurirwa zvinhu kuti kuti mhinduro beta2-adrenoceptor zvinhu.

The mushonga inokwanisa kuderedza huwandu potassium ions zvikuru muropa, nokudaro achiita kuvandudzwa anokuvadza pezvakaitwa mumwoyo uye nemidziyo. rutapudzo ichi muna K ⁺ ari yeplasma anoonekwa kuti kwenguva pfupi, hazvina haatarisiri replenishment. In kwazvo siyana Árbol mhingaidzo uye hypokalemia hwapedyo kushaya okisijeni. hypoxia Treatment kungada cardiac arrhythmia.

Inhalation kwokubatsira mukuru-dose zvinodhaka dzimwe kunowedzera muropa shuga yomuropa. Panyaya iyi, tinoratidza nokungwarira zvichiongororwa vanhu vari plasma wevasungwa shuga chirwere cheshuga. Kuti uzvidzivirire hyperglycemia havafaniri kushandisa mishonga kazhinji uye pamatunhu mishonga.

About medicament "Onbrez Brizhaler" nyanzvi mafungiro zvinoratidza murombo kugarisana zvinodhaka uye agonists beta2-adrenoceptor site ane refu chokupfeka.

Zvinoreva mashoko chete kubata obstructive kufema turakiti hurongwa kuchinja chirwere chimiro. Kana medicament zvisina kukodzera, akadai Árbol asima mhando, pane ngozi panowanikwa siyana zvakaoma umo murwere muchipatara uye vakatakura inubatsiyu.

No zvekuchipatara data, izvo kwaizoratidza Zvakaitwa indacaterol ari muitiro akatakura mwana pamberi chirwere obstructive pulmonary. Ndechipi zvinogona ine nezvainoita Muviri harizivikanwi. Vakadzi vari munzvimbo kubatwa zvinodhaka ichi kana unofanira kuwana inotarisirwa kubatsira kuti muviri kwaamai, izvo akapfuudza zvichibvira njodzi kuti mwana asati aberekwa. Kufanana nevamwe beta2-adrenergic agonists, mishonga relaxes anotsvedzerera tsandanyama ari dumbu, hunobata nesimba basa.

Panewo hapana ruzivo pamusoro raparadza indacaterol kana ayo metabolites mumukaka kwevanhu. Pane uchapupu kunyorerana chinoshingaira fuma, uyewo inhaled beta2-adrenergic vamiririri iri mammary omumuviri, iyo inosvitsa kudiwa pamusoro abolition zvinodhaka "Onbrez Brizhaler" achiyamwa.

Under nemadhiragi haisi nokuchinja kuorera varume nevakadzi, sezvinoratidzwa zvidzidzo dzokubereka nadzo.

The mushonga anogona kuva nezvahunoita chokufambisa zvakanaka kana basa pamwe zvigadziriswe yakaoma, sezvo hunokonzera tichibatwa dzungu uye havachanyatsogoni kutarisirwa.

Ndiani havafaniri kushandisa

The medicament "Onbrez Brizhaler" kurayira haushandi kana achaudzwa kunyanya aikanganiswa yezviri chirungiso, lactose kana zvimwe mamwe zvinoriumba.

Inhalation contraindicated vana pasi makore 18. Havadi kuti varwere vanenge kushaikwa Lapp-lactase, galactosemia, nhaka kusashivirira kuti lactose uye galactose mamorekuru.

Rinoreva "Onbrez Brizhaler": wongororo vanachiremba

Iye anonzi imwe Newest mishonga zvinhu kushandiswa mune obstructive pulmonary chirwere ari zvemapapu. Pane zvakawanda uchapupu efficacy uye kuchengeteka indacaterol. chokushandisa Izvi zvaisanganisira ari GOLD chirongwa dzine kurumbidza renyika kurapa echirwere obstructive pulmonary chirwere fomu.

miedzo Clinical yaiitwa pamwe kutora chikamu indacaterol vanenge 10 000 varwere vanenge chirwere ichi. Unowanikwa kuti kushingaira fuma ine chinokosha ukuru vanoshingaira pamusoro Pacifiers nezvimwe bronchodilators ano kuti zvinokosha kurapwa Khobzey.

On mishonga "Onbrez Brizhaler 'wongororo vanachiremba vanoti izvozvo ultradlitelnom chiito rimwe chete zuva nezuva kudya. The chigadzirwa anopa nokukurumidza bronchodilator efficacy pashure maminitsi mashanu pakupera evanhu.

Uyewo kuti mari "Onbrez Brizhaler" mhinduro anoratidza zvinoderedza mwero Kuipa mamiriro eutano pavarwere vane mhingaidzo pakati mumapapu. Panguva exacerbation kurwisa hurumende mberi nokukurumidza, murwere anoiswa muchipatara, panogona kuuya munhu inouraya mugumisiro. Muchipatara iri kudhura.

Zviri ano zvinodhaka kurapa Khobzey, chacho vanoshingaira mumiririri kuti mapapu nokuda inhalation pamusoro inhalation, iyo anoiswa Handheld mudziyo. The mushonga kunokonzera kutandara pamusoro anotsvedzerera tsandanyama ari Árbol sepombi, izvo zvinoita kuti akurumidze kuwedzera. Ichi chakakwirira kunyatsoshanda kunoderedza zviratidzo chirwere. Saka unogona kubvisa breathlessness pashure pemazuva 30 kubvira pakatanga evanhu. naizvozvo vakakodzerwa Kamudzira "Onbrez Brizhaler" nyaya dzinovaka. Kushandisa zvinodhaka anobvumira vanorwara munhu kuti kushingaira uye kutungamirira hwandaiva uye hunogutsa.

pfungwa wevarwere

A nzira "Onbrez Brizhaler" uchapupu vanhu vanotambura obstructive kukuvara yemapapu ari chirwere chimiro, achiratidza kubudirira inhalation. Pashure 5 mazuva kurapwa, varwere vakawanda vakaona zvinoderedza kupfupika mweya, uye pashure nzira yokurapa vanhu vakatanga kudzivisa, anenge kufema.

Capsules unogona kunzwiwa "Onbrez Brizhaler" wongororo kunaka. Vari chokuita nechitarisiko vamwe varwere akaora chinokosha zvemwoyo migumisiro. Izvi zvinosanganisira wakawedzera kwemwoyo uye cheBP. Kana zvakadaro kunoda kubviswa kurapwa pamwe mumiririri uyu.

analogs

Musoro medicament "Onbrez Brizhaler" kureva bronchodilator mishonga matanho anokosha. Ane waivako nani zvichienzaniswa mishonga pamusana salmeterol, formoterol uye tiotropium.

Medicament "Flomax" anonzi kuva analogue zvinodhaka Swiss. Inoitwa tiotropium bromide iro rinoshandiswa sezvo antiasthmatic zvinoriumba. It anogadzirwa muchimiro capsules, upfu zviri kuti inhalation ari dose kuti 0,018 MG. The rongedza rine zvidimbu 30 vavo, kuti izvo wanamatira imwe inhaler.

Chimwe nzira dzakadaro anonzi zvinodhaka "Salmeterol" sezvo metered aerosol nokuda inhalation. Mumwe dose mabhati 0,025 MG kana 0,050 MG salmeterol. Rinoreva kuti bronchodilator, sarudza beta2-Adrenomimeticalkie chiito.

Kusarudza agonist chiito pamusoro β2-adrenoretseptery zvinodhaka ndiko "formoterol" muchimiro upfu pamusoro inhalation, icho mumapepa mu capsules. Drug zvakaipa Árbol mhingaidzo mu obstructive zvirwere zvemapapu, bronchospasm mu asima, chisimbwa kuti mhepo inotonhora kana muviri.