'Sulfasalazine' zvinoreva. Mirayiridzo yokushandisa

The mushonga "sulfasalazine Eh" rinorambidza anogumbura, Anti-rheumatic, immunosuppressive, intestinal bacteriostatic mumiririri. The mashandiro chiito inobva yezviri zvinoriumba zvinodhaka ehupfumi.

Zvinobudirira salazosulfapyridine fuma chiri mushonga kubva boka sulphonamides. Rokuti ane bacteriostatic basa pamusoro gonococcus, streptococci, diplococci, E. coli.

Active chirungiso 5-aminosalitsillovaya asidhi ane Anti-anogumbura ehupfumi, rinobatsira kuti kudzvinyirira pamusoro prostaglandin usage uye chinovhiringidza kuti cyclooxygenase.

Rinoreva "Sulfasalazine" (mirayiridzo kushandiswa rine mashoko akadaro) inoperera kuchinja lymphocytes uye kuchititadzisa monocytes. The mushonga kunokanganisa cellular, uye humoral kutapata.

The medicament iri havaratidzi woga kubva nemudumbu.

The mushonga "Sulfasalazine" mirayiridzo Chinyorwa anokurudzira kuti mune maronda proctitis, nonspecific colitis (maronda). In pathologies izvi, kuti medicament zvaishandiswa pakurapa exacerbations uye sezvo yokuzvigadzirisa marapirwo ari kanganwiro.

Rinoreva "Sulfasalazine" mirayiridzo Chinyorwa anokurudzira ari Crohn nehosha (pa mwero uye nounyoro siyana exacerbation).

The mushonga zvakare nachiremba dzinonzi rheumatoid arthritis (hwanana pamwe).

Medicament "Sulfasalazine" mirayiridzo Chinyorwa anokurudzira kuti pashure kudya. The chipimo chemushonga inofanira kusimbiswa nomumwe zvinoenderana kwokuomerwa zviratidzo uye zvingakonzerwa nemishonga.

Kazhinji, munhu mukuru yakagoverwa 500 kusvika 2000 milligrams runa pazuva kuderedza chirwere zviratidzo. Zvadaro, murwere akachinjirwa yokuzvigadzirisa kurapwa. The chipimo chemushonga muchiitiko ichi - 500 milligrams katatu, vana kanomwe pazuva. Duration kurapwa - mishoma.

The chipimo chemushonga vana kubva mashanu makore manomwe - 250-500 milligrams matatu kusvika katanhatu pazuva, makore manomwe - nguva 0.5 magiramu matatu kusvika matanhatu pazuva.

Adult kuchirapa dose - 1.5-3 magiramu. Sezvo tsika zvinoratidza, mugumisiro kunoitika pashure matanhatu kusvika gumi vhiki. Ramba kurapa kwemwedzi dzinenge mitanhatu.

The mushonga iri contraindicated vanenge kupererwa, porphyria, chinoratidzwa zvirwere chiropa kana itsvo, hypersensitivity (kusanganisira salicylates, sulfonamides). Regai taurira mushonga "Sulfasalazine" vana makore mashanu. Chiri contraindicated panguva lactation. Kana zvakakodzera, kushandisa mishonga paanenge achiyamwa, vanofanira kusarudza kugumiswa lactation.

Panguva pamuviri, mushonga inogona raitongwa zvakasimba maererano zvairatidza ari shoma kuchirapa dose pasi zvokurapa achitarisirwa. Hatina kutokurudzira kutora zvinodhaka "Sulfasalazine" iri chekupedzisira chemwedzi mitatu yenhumbu.

Vazhinji kukanganiswa zviitiko medicament chipimo chemushonga kunobva wokurera uye mugumisiro basa salazosulfapiridina (active chirungiso).

The mushonga anogona kukonzera peripheral nephropathy, dzungu, interstitial nephritis, kushaya hope, tinnitus. Munguva pakurapa zvirwere kunogona kuitika munguva itsvo, manyoka, kupererwa neropa, maronda ari zvemapapu rinenge leukopenia, kushaya mbereko uye oligospermia (inopfuura). Nenjodzi uyewo kurutsa, pfungwa nomuviri zvemwana asati, agranulocytosis, anaphylactic kuvhunduka, kupererwa neropa, urticaria. Mune zvisingawanzoitiki Muzviitiko, chirwere ichi chinogona kuonekwa mune peripheral tsinga basa, ganda zvavaifunga.

Over kushandiswa zvinodhaka inokurudzirwa kuti tikanwa zvinwiwa zvakawanda.

Hapana uchapupu kana zvinodhaka "Sulfasalazine" analogs yezviri fuma.

Asati kushandisa zvinodhaka, nyanzvi dzinokurudzira kuzivana naye pfupiso.