Thyroid mahormone: panobva, kukosha zvokurwara

The muviri womunhu - a coherent maitiro umo pezvakaitwa zvose vari nokudzorwa mumwe. Uye muviri wose wayo sezvamunoita chinowedzera kuramba kuvimbika basa.

Pamwe uropi ndechimwe chezvinhu zvinokosha pamutemo zvigadziriswe - the kwemakemikari anobudiswa kwevanhu hurongwa. It anoita chiito yawo kwemakemikari anobudiswa omumuviri, izvo secrete mahormone rine zvimwe zvinhu uye yakananga tropism nokuda chipfuro masero. Saka thyroid shwanu inoita basa rinokosha mumuviri kukura uye kunokanganisa mhando dzose exchange. Iye rinozivisa thyroid mahormone, iyo inobatsira kuti mumuviri, mupfungwa kukura mune vana, zvinopa muviri uye simba nedzevakuru. Uyewo, kugadzirwa yavo nokudzorwa tsinga, kureva bioactive zvinhu pituitary uye hypothalamic anosunungura zvikonzero. Saka, thyroid mahormone nguva dzose pane pamwero muropa uye kuwedzera muviri kunyatsotarisirwa, nhoko dzavo anogonawo kunoratidza kusava thyroid nerevane ayodhini.

mahormone

Glandula thyroidea (thyroid) wanamatira kuti trachea uye chinosanganisira kurudyi nekuruboshwe lobes chokuita nevanhu nekamukwavarara. Direct kwetunhu thyroid mahormone rinoitwa mu follicles ayo akazara colloid mukati, iyo yakavakirwa mapuroteni - thyroglobulin. Mimwe iodination kuti tyrosine residues kwayo marongerwo kwaizotevera summation pamusoro yeimwe vakawana uye kuumbwa triiodothyronine uye tetraiodothyronine (T3 uye T4). Uyezve tireiodnye mahormone zvinobva thyroglobulin Morekuru wakanamatira uye akasunungura kupinda muropa murusununguko chimiro. Vane kuwanda siyana, uye dzinosiyana potency (T3 anomira yekudyidzana dzakaderera mishonga, asi ayo potency chikuru zvikuru kupfuura T4). Zvisinei, maratidzirwo mahormone pamusoro muviri zvakafanana: runogonesa mafuta uye carbohydrate muviri (wakawedzera shuga yomuropa) rukungiso gluconeogenesis, chiropa glycogen tunodzivisa inotungamirwa uye kuwedzera mapuroteni usage (nenzira kunyanya mari, Ukuwo, kuwedzera disintegration wevakabhuroka).

It kunoratidzwa yokuti varambe BP uye kwemwoyo uye muviri tembiricha, mhanyisa mupfungwa kwendangariro. In embryonic nguva thyroid mahormone ndivo mhosva Kusiyanisa kuti nyama yose muviri. In pauduku, inobatsira kuti kukura mupfungwa mwana. Mukuwedzera, ivo tiwedzere erythropoiesis, nechepazasi tubular reabsorption mvura.

chirwere

Mune dzimwe zvirwere, thyroid kemikari secretion ipfupi (hypothyroidism). Muchiitiko chino, anofanira kutsiviwa nemishonga. Izvozvo zvinogona kuko- nokushayikwa kugutsikana zvinhu zvakadaro BAKC thyroid mahormone? Drugs akashandiswa iyi - ndiye "Levothyroxine" (T4), "Liotironin" (T3) uye zvakasiyana-siyana zvinodhaka ayodhini tubhokisi. Sezvo kuvamirira, uye nekumwisa thyroid mahormone kukonzera metabolic zvirwere mumuviri kuti vari akaora pachena kutyorwa homeostasis uye psychomotor basa. The dhigirii kukuvara kunobva murwere zera (cretinism chete kuvana), padanho yokushomeka kana nekumwisa mahormone (hyperthyroidism 1, 2, 3 madhigirii). Pakupedzisira pane kupfupika mweya, palpitations, wakawedzera BP, kusagadzikana siyana exchange. Nokusava nekusiyana, ndokuramba muviri, murwere inova usimbe, hanya.