Types uye jekiseni chiito. tafura

Modern pharmacology inopa chirwere cheshuga guru zvakawanda jekiseni gadziriro. Uye nhasi tichataura pamusoro chii mhando jekiseni vari.

Jekiseni: Types

iripo gadziriro All jekiseni vanokamurwa muzvikamu zvitatu (zvichienderana chiito uye mishonga mugumisiro nguva):

• "Short";
• "Medium";
• "Long".

"Short" insulins

Zviri pfupi-kuita jekiseni kugadzirira kunowanzoitwa ushandiswe varwere vane ropa shuga nematambudziko.

Mushure pomutumwa anopinda muviri, rwunotanga kushanda mukati maminitsi matatu. Izvi rinoshandurwa nawo zvikuru vakarongeka kuerera nemishonga inoshandiswa pakurapa chirwere cheshuga. Kazhinji, kwakadai jekiseni raitongwa pamwe jekiseni kwenguva refu chiito.

Kuti tizive sarudzo, unofanira kufunga zvinhu zvinotevera:

• General ezvinhu omurwere;
• kupinza nzvimbo zvinoreva;
• chipimo chemushonga.

The inonyanya kufarirwa jekiseni kugadzirira anotanga kuita munguva maminitsi 15 pashure nehurumende wokutanga. Zvinoreva "Apidra", "Humagol" uye "Novorapid".

Features

Pakati mukuru-nokukurumidza kwevanhu jekiseni gadziriro ndiko kupa "Homorap" uye "Rapid Insumad". Musiyano pakati pavo iri kushanda kwete. The musiyano chete - mu uwandu Zvakasara aripo kwayo Zvinoumba amino acids.

By insulins "nokukurumidza" mhuka mavambo ndeyakewo zvinodhaka "Insulrap SPP", "Iletin II Kugara" uye vamwe. Vari anowanzodanwa nachiremba mhando II cheshuga. Mari kubva muchikwata ichi vanosanganisira kwayo Zvinoumba mapuroteni ane zvakasiyana chimiro, uye saka hazvisi akakodzera varwere vose. Somuenzaniso, "Kutsanya," insulins mhuka mavambo hakufaniri nachiremba vanhu vane miviri havasi vanokwanisa processing lipids mhuka.

Mabiko, chipimo chemushonga, kuchengetera "pfupi" insulin yakakodzera

Kutora zvinodhaka pakarepo pamberi zvokudya. Muchiitiko chino, izvozvo Inowedzera kugaya zvokudya jekiseni maturo kunoitika anenge pakarepo.

"Fast" jekiseni anogona kupiwa nemuromo pre-kudyara kuti imvura ezvinhu.

Kana tsika subcutaneous kwokubatsira zvinodhaka, asi jekiseni ngazviitwe anenge 30 maminitsi asati yakarongwa kudya.

The chipimo chemushonga mumwe munhu ane chirwere cheshuga, vakasarudzwa nomumwe. Adult dose achava 8-24 inokwana zviyero pazuva, uye vana - hapana kupfuura 8 dzakabatana.

Tuvana gadziriro pa + 2- + 8 inegumi. Nokuti ichi zvakakodzera pasherefu pamusuwo mufiriji.

"Avhareji" insulins

Chirwere cheshuga vanofanira kutora zvinodhaka kuti dzinotsigira vakakwana ropa shuga yomuropa. Asi mumwe mhando chirwere cheshuga zvinoda mumwe mhando jekiseni. Sezvo mushonga une avhareji kureba, rinoshandiswa panyaya apo shuga inoda zvishoma nezvishoma cleavage. Asi zvinogona kushandiswa, kana pari zvisingaiti kushandisa "pfupi" jekiseni.

Zviri "pakati" insulin yakakodzera

Drugs vane akawanda zvinhu:

• vanotora zvazviri achangogara maminitsi 10 pashure adhimini;
• zvinoreva zvinotora zvikuru nguva refu kuti apedzise disintegration.

Insulins izvi mhando kunogona zvakasiyana kushingaira chawo, zvikurukuru, jekiseni isophane kana zinc. Zvikurukuru zvakanaka nekusimba zvinotevera zvinodhaka:

• pakati jekiseni dzevanhu - rinoreva "Protafan", "Humulin", "Monotard" uye "Homolong";
• pakati mhuka pfuma - mishonga "Berlinsulin", "Monotard HM" uye "Iletin II".

"Long" insulins

Kuti nenguva nhanganyaya zvinodhaka achibvumira chirwere cheshuga vanakidzwe noupenyu pasina kusagadzikana kunokonzerwa nemupristi zviri shuga muropa. Chii chinosiyanisa ichi mhando jekiseni kugadzirira nemamwe marudzi uye vane-refu achiita jekiseni zviripo - hurukuro iyi.

Jekiseni musiyano mukuru hazvisi kuti kubata zvinodhaka dzimwe nguva inogara refu kupfuura maawa 24.

Uyezve, marudzi ose refu-kuita jekiseni racho sezvamunoita zvine makemikari catalysts kuti pave-refu nokushanda zvinodhaka. Naivowo kunonotsa Absorção de Água kuti shuga. The kuchirapa nezvinozoitika maawa anenge 4-6 uye nguva chiito kunogona kuva maawa anosvika 36.

Long-kuita jekiseni: chii siyana zviripo

The anowanzodanwa ushandiswe mishonga ndivo "deterministic" uye "glargine". The musiyano mukuru - kunyange ropa shoma.

Insulins pamwe kwenguva refu nguva chiito ndeyakewo kugadzirira "Ultratard," "Ultralente iletin-1", "Huminsulin" "Ultralong" etc.

Somushonga zvigadzirwa vari chairayirwa kupinda chiremba, izvo mberi kunobatsira kudzivisa matambudziko akasiyana-siyana ari muchimiro nemishonga.

Use uye kuchengetera mushonga

Jekiseni ichi mhando kunogona kutarisirwa chete jekiseni. kamwe chete mumuviri zvokuti anotanga kushanda. Anobaya kuisa honokono, chidya kana buttock.

Asati kushandiswa, chinu anofanira kuzununguswa kubatanidza mariri vakatodzidza rekuchikoro kusachinja-chinja. Pashure kuti takagadzirira kushandiswa.

The sezvamunoita anochengeterwa pasi chete ezvinhu sezvo pfupi-kuita jekiseni. Kwakadaro tembiricha kuzvidzora kunodzivisa paumbwe flakes uye pelletising musanganiswa, uyewo oxidized zvinodhaka.

Baya jekiseni jekiseni oga, dzimwe nguva kaviri pazuva.

Rakatanga jekiseni

Kusiyana jekiseni - kwete chete panguva chiito, asi mavambo. Govera zvinodhaka mhuka uye jekiseni akafanana vanhu.

Nokuti muchikwata mishonga rokutanga inoshandisa rwatata renguruve uye mombe. The zvipenyu maumbirwo jekiseni anobudiswa kubva nhengo yenguruve, zvakakodzera vanhu zvikuru. Musiyano hazvisi vasingakoshi chaizvo - mumwe chete amino acid.

Asi yakanakisisa zvinodhaka Chokwadi, insulins yevanhu, izvo anoshandiswa kakawanda. Achishandisa kugadzirwa zvinogoneka nenzira mbiri:

1. nzira yokutanga ndiyo yokutsiva mumwe amino kukodzera. Muchiitiko chino, munhu semisynthetic jekiseni.
2. Mune nzira kubudisa mushonga zvinobatanidzwa E. coli wechipiri, kukwanisa synthesize mapuroteni. Izvi uchava biosynthetic nzira.

Similar vanhu jekiseni kugadzirira vane uwandu zvakanakira:

• kubudisa kutsvakwa kuchirapa kushanda zvinoda kutungamirira mishonga zviduku;
• lipodystrophy kukura kunoitika nekaupenyu Kazhinji;
• chisimbwa kune zvinodhaka riri kushanda kwete kuchengetwa.

dhigirii yokuzvinatsa

Zvichienderana mwero yokuchenesa akakamurwa:

• chinyakare;
• monopikovye;
• monocomponent.

Traditional insulins vari pakati wokutanga jekiseni kugadzirira. Ivo zviri zvayo sezvamunoita guru siyana mapuroteni tsvina, iyo yakava mhaka kakawanda neutachiona. Pari kugadzirwa gadziriro yakadaro yekudyidzana ipfupi.

Zvinoreva Monopikovye jekiseni ane shoma nouipi (mukati zvinogamuchirika mwero). Asi monocomponent insulins anenge akachena zvakakwana, nokuti mari nouipi vasingadiwi, kunyange isingasviki rezasi muganhu.

misiyano mikuru "pfupi" uye "nguva" jekiseni

Sezvaunogona kuona, Mhando jekiseni (Table inoratidza zvakajeka izvi) zvisingapindirani anokosha zviratidzo. Uye izvi zvimwe zvinhu zvinoda kuonekwa.

Takurukura mhando dzose iripo insulin yakakodzera uye zvazvinoita pane dzemuviri. Tinovimba kuti mashoko zvave zvichibatsira. Stay utano!