"Asparkam": kushanda uye rondedzero zvinodhaka

Kugadzirira "Asparkam" riri antiarrhythmic, diuretic zvinodhaka, chinangwa nokuda kudzorerwa electrolyte kusaenzana. The medicament rine wayo sezvamunoita ari potassium uye magnesium zvienzane zvikuru, i.e. avo zvinhu izvo zvinodiwa zvose metabolic kwendangariro.

Rinorevawo "Asparkam" kushanda riri zvemitambo. Somugumisiro migumisiro yayo pamusoro muviri kunowedzera nhamba mano chaiko kwevanhu. Somuenzaniso, "Asparkam" iri mukusimbisa muviri zvakakosha kutora kuti uderedze uremu. It kunodiwawo mukufamba kurovedza munzvimbo inopisa. mushonga uyu unobatsira pakarepo panowanikwa nezvipusha, sezvo anowedzera zviri K ions uye MG muchitokisi, uye compensates nokuda kushayikwa aspartic asidhi zvinoshamisa Inowedzera oxidative phosphorylation uye mberi inotungamirwa ATP. The chinodhaka yekudyidzana zvinowedzera mataurire chose zvose zviri skeletal tsandanyama uye optimizes ari motility ari nemudumbu (nokuda zvakazorodza acetylcholine kusunungurwa).

Kutyora Exchange K + sezvinoita mutemo, zvinotungamirira zvachinja excitability pamusoro pezvakaitwa tsinga uye naizvozvo tsandanyama. Yakakwana kufamba ions anoramba guru chaizvo gradient pamusoro K + H \ h yeplasma membrane. Mune rimwe asi duku mishonga pakati K + kunowedzera lumen ari coronary arteries, uye makuru - Narrows. Kureva zvinodhaka ane kunaka chronotropic chiito BATM uye, panguva dzakakwirira mishonga uye kwakakanganisa dromo- inotropic uye diuretic chiito ane srednevyrazhennym.

MG 2+ - Nde cofactor 300 enzymatic siyana. Uyewo chinhu chinokosha, izvo mune simba zvekushandisa.

The zvinoumba Pfungwa iyi zviri kuitika mu pakuenzanisa electrolytes, ivo ions ichifamba, Kamudzira permeability uye neuromuscular excitability.

MG 2+ rwuripowo maumbirwo DNA rinobatanidzwa mu RNA usage, tenzi chairema yedzinza, kukura masero panguva muchitokisi nokupesana.

Izvi mushonga "Asparkam" kushanda haiiti ayo nechokumusoro. It normalizes zvakawandisa catecholamine kusunungurwa mu mwoyo ezvinhu, uye pazvinobvira humwe lipolysis goho akasununguka mafuta acids.

Pregnant mushonga "Asparkam" chikumbiro zvinobvira muna aakatipa nguva kubva migumisiro ingestion vane pamuviri asi kurondedzerwa. Saka pane izvi, asati achitora nani kubvunza chiremba.

Drug "Asparkam" ane contraindications pakushandisa duku, ndiyo chero chimiro renal kukundikana uye hyperkalemia.

Funga nemishonga kuti zvinodhaka anogona nhaka. Somuenzaniso, zvinokwanisika kuda kurutsa, kusagadzikana kunogona kuitika zvishomanana unopfuta manzwiro ari epigastric nharaunda. Izvi zviitiko chaizvo kutsanya, kana nzira yokuderedza uwandu husingakuvadzi.

Chipimo chemushonga uye nzira chikumbiro "Asparkama" sezvinotevera: mushonga chinotarisirwa nomutsinga, aizomupa kana kuburikidza rinokosha metering mudziyo maererano "richadzipa".

For intravenous aizomupa mushonga, riri iri 1-2 Rine mamiririta ampoules 10 kana 2-4 ampoules 5 Rine mamiririta, rakasanganiswa 200 Rine mamiririta phys. mhinduro kana 5% D-shuga p.

Ya kurapwa "Asparkam" chinodhaka (kurishandisa pasina yokumbozorora) kunotemwa chete nokuda kupinda chiremba. Asi somunhu mutemo, ichi nguva hazvirevi kupfuudza mazuva gumi.

Tinofanirawo kutaura pamusoro zvichibvira migumisiro zvinodhaka ovhadhozi. Kana wakanyanya nokukurumidza intravenous kwokubatsira mushonga kana zvinodhaka kana achiita panguva dzakakwirira mishonga, anogona kuva hyperkalemia uye hypermagnesemia. Zvinonzi akaratidza kwazvo Hwakatsvuka ganda, nyota, pasi BP,-siyana pfari.

Muzviitiko zvakadaro, kukurumidza kukumbira rubatsiro. Kazhinji, kukurumidza karusiyamu gluconate mhinduro kutaurwa kana sezvo karusiyamu chloride 10% ari chipimo chemushonga pamusoro 10-40 Rine mamiririta (zvichienderana mwero zvakaoma ovhadhozi), akaita kuti normalize afemeruke uye hemodynamics zvimwe zvakakodzera symptomatic kurapwa.