Follicular rwekenza yelymphoma: zviratidzo, zvinokonzera, kurapwa. Nguva kuregererwa uye kuitazve follicular rwekenza yelymphoma

Rwekenza yelymphoma akadana chirwere chinobata ari nhengo dzinobudisa tishu. Panyaya iyi, njodzi masero otanga uye muchisimbisa vanotsamwisa disruptions mune chakaipa nokushanda kwenhengo zvomukati dzemuviri. Kure boka zvirwere zvakadai: Hodgkin nehosha (kana inonzi Hodgkin nehosha) uye vasiri Hodgkin kuti rwekenza yelymphoma (kusanganisira follicular vasiri Hodgkin rwekenza yelymphoma).

The nhengo dzinobudisa hurongwa. Chiiko ichi

Chikamu rokuzvidzivirira muviri wedu ndiye node, chikuru basa iyo - kudzivirira ose zvirwere nezvimwe zvirwere. Zviri richikurukura mugero kuburikidza iyo Urume runoita yakazonaka - node. Nokufamba capillaries vakachengeta node nodes apo node kunowedzerwa nemasero anokosha - lymphocytes. Pane subspecies akawanda. B lymphocytes ndivo mutoro vawana kutapata kuti zvirwere. Contact pamwe nayo utachiona, kubvisa zvachinokonzera uye kuzviisa mundangariro mangu. B lymphocytes - ndivo vamiririri zvinokosha paumbwe Mugumisiro kubaya. Most (80%) node vanoumba T lymphocytes. Ndivo kukonzera kuparara yamarudzi ose utachiona, mabhakitiriya. NK-masero zvinowanikwa node duku shoma (kusvika 10%). chikuru basa ravo - kuparadzwa zvaparadzwa masero vayo (kusanganisira chirwere ichi zvakadai follicular rwekenza yelymphoma).

Sei akaipa kwacho nhengo dzinobudisa ino

Neoplastic muitiro kachitanga kubva masero ari nhengo dzinobudisa ino (B masero). Maperembudzi panoonekwa kunyanya vakwegura, mune vana kuitika mune zvisingawanzoitiki zviitiko. Follicular rwekenza yelymphoma vakagamuchira zita raro nokuti kuti achinyanya inokanganisa vhudzi follicle. Kakawanda, namamota vari kuchengetwa pamutsipa, muhapwa, muhudyu. The peculiarity rwekenza yelymphoma uyu kuti varwere vanotsvaka rubatsiro kunonoka. The zvakakanganisa masero kupinda munzvimbo dzose zvomukati, vachivhiringidza basa ravo. Kunyange follicular rwekenza yelymphoma iiia zvakakwana anongokurukurwa zvakanaka kurapa, pashure nzendo nechirwere hatibvumiri kuti zvachose kubvisa chirwere.

Possible zvinokonzera chirwere

Chaiwo Zvikonzero kuti pave kukura kenza, nyanzvi haagoni kunzi. Zvisinei, pane zvakawanda zvinoita kuti vawedzere mukana malignancy. Mumwe wavo - Gene kunotouraya, chromosome. Kushanda vanoshorwa ezvinhu, zvachose kuonana ngozi vangabatsirawo anowedzera kuti mamiriro akadai follicular rwekenza yelymphoma. Zvinokonzera chirwere angava sezvinotevera: nemwaranzi dzokupisa, immunodeficiency kwakaderera muviri, uye autoimmune chirwere. Dzimwe nyanzvi kusiyanisa zvinhu zvakadai sokusvuta, akatora vamwe mishonga, uye kunyange kufutisa.

symptomatology rwekenza yelymphoma

Follicular rwekenza yelymphoma zviratidzo zviri nani simba, kunyanya kuchava kutanga kwekupwanyiwa. Chokutanga, kwave kune vamwe kuwedzera node nodes. Zvisinei, vava nyarara. Characteristically, kuti zvishomanana pakazvimba nguva anonyangarika, ipapo anoonekazve. Izvi zvinofanira kuva kunyanya kungwarira. Wedzerai muzvikamu uye sternum. Externally inogona kuratidzwa vangakosora, kupfupika mweya. Mukana duku run-kure nechiso. Mune zvimwe zviitiko, kutambura uye chirwatata. Follicular rwekenza yelymphoma zviratidzo zvinogona kuva zvakajairika: uremu, mukuru kuneta, utera muviri. Zvisinei, zviratidzo izvi - Kusara pane mutemo, vari kuchengetwa murwere mumwe chete kubva gumi. More chakakomba nzendo chirwere vanoonekwa ne kukuvara tsinga, kunyanya mumwongo. Panguva pfungwa dzungu, kuda kurutsa, uye pazvinobvira kufenda.

Kupatsanura kenza uye nzendo kuyerera

Kune mhando dzakawanda rwekenza yelymphoma. First - follicular. Zviri follicles hazvisi 75%. Kana pane vari kuwanda 25-75%, ichi ndicho follicular-diffuse subspecies. Mugore diffuse mhando kucherechedza asingasviki 25% follicles. Follicular rwekenza yelymphoma (iiia) kunoitika mumatanho dzakawanda. Panguva kutanga kwekupwanyiwa, nzvimbo imwe chete ari sei node nodes. Danho rechipiri iri dzinoratidzwa pathological muitiro chokuita migove miviri kana kupfuura (asi uri chete kurutivi diaphragm). Apo yechitatu-dhigirii sei nharaunda pamusoro mativi ose diaphragm. Wakakura zvikuru Danho mana. Kuchinja kuitika mune nhengo dzomukati uye hurongwa (nemwongo yawo, chiropa, etc.). Dzimwe nguva sezviverengo pavaipfuura rwekenza yelymphoma kuwedzera tsamba A kana B. Izvi zvinoratidza kuti follicular rwekenza yelymphoma zviratidzo zvinotevera mhando: "B" - pane kuchinja tembiricha muviri (uchitombova kuwedzera), uremu, vangadikitira usiku. Rwekenza yelymphoma C chivakashure "A" - humboo hapana zviratidzo.

Nzira diagnosing rwekenza yelymphoma

Chokutanga, nyanzvi (onco-hematologist) kuitisa kutarisana kuzviongorora murwere. Hazvina fanira histological kuongororwa dzokuenzanisira. Kuti aite izvi, mumwe biopsy rinoitwa. A chidimbu njodzi node raiva pedyo nebundu yabviswa uye aongororwe maikorosikopu. Zvinokosha kucherechedza matatu cytological Chirwere kuti inoda zvakasiyana. Chokutanga mhando kunoratidzwa pamberi centroblasts anosvika mashanu mumunda maonero maikorosikopu, wechipiri - kusvika 15 dzakabatana. Rudzi cytological kuvhunduka rechipiri zvinoda mishonga nokuti zvakakwana zvechisimba. Follicular rwekenza yelymphoma 3a cytological mhando ine zvikuru zvisingafadzi. fungidziro. Mumunda maonero maikorosikopu unokwanisa kuona zvakawanda anomera. Mukuwedzera, murwere unofanira kupa ropa (bundu zvezvinangwa, zvinonyatsorehwa pachisara), kupfuura Ultrasound kuongorora nhengo dzomukati, CT kana MRI. Kuti aone kana akarova nechepakati tsinga, musana vakabata fenzi kutsvakurudza zvimwe pamusoro kenza.

Follicular rwekenza yelymphoma. mabatiro

Mumakore achangopfuura, nhamba varwere chirwere chakadai yakawedzera zvinooneka. Kazhinji, kwokutanga akatadza kuona growths, nani murwere mikana kuchengetedza utano hwavo uye upenyu. Rwekenza yelymphoma kunoratidzwa munhu zvakanaka usimbe pamusoro, saka mune zvimwe zviitiko chiremba kusarudza rokumirira mutambo, vakatarira zvose kuchinja mumuviri womunhu. Izvi imhaka yokuti vaviri mishonga uye kuvhiyiwa haina vaedzwa zvakakwana uye mativi avo akaipa. Follicular rwekenza yelymphoma kuregererwa anogona kugara kwemakore akawanda. Kana mberi kenza kunotanga, mishonga yaifanira pakarepo. Pakati huru nzira kurapwa zvinofanira kuitwa nemwaranzi, mishonga, mishonga zvinodhaka. Zvichienderana rudzi rwekenza yelymphoma, remunharaunda kunogona kudzivisa zvinobvira zvazvo. In padariro wokutanga chirwere ya rekuregererwa chakanyorwa varwere vakawanda.

akatakura mishonga

Aggressive mishonga (uye zvinodhaka zvinganaka akawanda) mu tanga rwekenza yelymphoma kunogona kuderedza mukana wokuti dzokororo. Kwenguva refu nzira iyi kwainzi chikuru kurapwa kenza. Mishonga nechinangwa kuparadzwa bundu masero panguva chokuwanziridza yavo. Combination Formulations vanogona kufurira chirongwa weboka muzvikamu zvakasiyana, saka avo kushandiswa zvinobudirira. Zvisinei, mishonga ine kukuvadza pane dzimwe nhengo (ganda, bvudzi, uye zvichingodaro. N.). Chirwere zvinodhaka izvi uye mwongo. Panguva mushonga, munhu anova zvikuru kubatwa nezvirwere zvinotapukira kuonekwe akawanda mavanga uye ropa. kurapwa mishonga kazhinji kukonzera kunowedzerwa kugadzirwa uric acid, zvinoita kuti paumbwe itsvo namabwe. Zvisinei, zvose nenjodzi inonyangarika pashure pemavhiki mashomanana pashure kosi. Zvinofanira kucherechedzwa kuti vamwe mishonga zvinodhaka anogona kuderedza dzisingaoneki rikoshe nevanhu, afunge kushaya mbereko vakadzi.

Treatment pamwe Monoclonal Antibodies

Follicular rwekenza yelymphoma ikarapwa, uye mishonga mitsva zvakadaro monoclonal antibodies. Ivo zvinechinangwa kuparadza chete rwekenza yelymphoma masero. chidobi Izvi zvinonyatsoshanda akabatana mishonga. Monoclonal antibodies zvishoma kuderedza toxicity kuti makemikari. Varwere dzakaona ya rekukangamwirwa follicular rwekenza yelymphoma. Mune zvimwe zviitiko, zvinoita sema maitiro, saka kwokubatsira antibodies zvichiitika kwenguva yakati yokutanga. murwere pamberi kurapwa waida mwero antiallergic zvinodhaka.

chirwere dzokororo

Danae chirwere dzinoratidzwa anononoka kufambira mberi mune tanga, kuregererwa nguva anogona kugara kusvika makore 20. Kazhinji idzokororo follicular rwekenza yelymphoma kuchengetwa mhando 3a cytology. Muchiitiko chino, ungada kubvisa muchitokisi transplantation. Anenge apa wacho anoderedzerwa kunogona kuva mukoma (hanzvadzi), uye hama asiri ropa. The nzira rinoitwa Varwere kwete vanopfuura makore 70, inova ikarumbidzwa yakanaka kuti mishonga uye kuva inogutsa mamiriro utano. Mushure transplantation, kuvandudzwa zvinochengetwa munenge hafu varwere. Survival inotsamira zvinhu zvakawanda. Chokutanga, pavaipfuura chirwere kuchikosha, Morphology kuchinja (nokufanotaurirwa follicular rwekenza yelymphoma nani vanoshorwa iri danho rechina). Zvinofanira kucherechedzwa kuti kutsungirira nani pamwe chirwere zvevechiduku. Zvakakosha kuti ticherechedze rwekenza yelymphoma nenguva, saka hatiregi chokudzivirira bvunzo kubudikidza unyanzvi.