Nemakemikari Kuongororwa kweropa. Alt uye AST: decoding waivako

Alanine, kana alt uye aspartate aminotransferase, kana AST, muri makemikari, izvo huri mumasero omuviri, uye vanobatanidzwa amino asidhi muviri. Ivo dziri chete masero nhengo dzomuviri uye ropa kupinda masero kunoitika chete kana kuora muzviverengero zvinokatyamadza makuvaro kana pathologies.

siyana zvirwere

Kunwisa kwevari alt kunoratidza kukura nhengo pathologies mumasero izvo zviripo ndiro kupfuura nhamba. Pane zvikonzero zvibereko alanine aminotransferase chiropa zvokurwara. Kusagadzikana uye marwadzo zvakarurama yokumusoro quadrant, manyoka, icteric staining ganda uye mucous membranes, flatulence, belching shungu - Ndiwo zviratidzo kuwedzera alt. Paaiita miedzo ropa kuti vawedzere alt uye AST anobatana kwakakwidziridzwa bilirubin yomuropa, apo pane kukura nehepatitis. Kazhinji Zvakawanikwa alt inoratidza chidzoke vamwe zvirwere. Alt wevasungwa uri zvakananga novimba mwero chirwere nekuomarara.

Necrotic kwacho cardiac tsandanyama muropa kunokonzera kusunungurwa makemikari izvi. Inosimudzira serum yavo inotaura pamusoro pokumuka mamwe kardiopatology: kukundikana, kuzvimba mwoyo tsandanyama. Uyezve, zvikonzero kuwedzera serum alt kuwanda anogona kuvapo ari kukuvara mumuviri ayo chokuita kukuvara tsandanyama rinenge uye pfungwa nomuviri zvemwana asati.

Nemakemikari Kuongororwa ropa pamusoro alt uye AST zvingaratidza chiropa chirwere, rwatata, mwoyo. Kana kardioinfarkte AST wevasungwa kunowedzera kakawanda, uye alt - zvishoma.

zvairatidza kuti

Nhengo dzemuviri zvine uwandu makemikari alt uye AST zvakasiyana, saka kuwedzera wevasungwa imwe enzayemu rinoratidza yakananga nhego maronda:

• alt dzinowanzotsigi- iri pachiropa, mwoyo, itsvo uye pancreatic masero. Kana kuparadzwa mitumbi izvi muropa asunungurwa yakawanda alt. Zvadaro, kusimbisa chirwere zvinokosha kudzidza panzvimbo alanine aminotransferase.

• AST dzinowanzotsigi- kuwanikwa tsinga, tsandanyama, chiropa uye mwoyo masero, uye mune miduku iri mumasero rwatata, yemapapu uye itsvo munyama. Saka, iyi nyaya yokudzidza ari aspartate aminotransferase.

A bvunzo ropa alt uye AST (inopangidza) inoratidza mamiriro nhengo. Kuwedzera kwavo uchapupu zvinyama kukuvara nhengo umo makemikari izvi dziri. Uye, naizvozvovo, akaderedza uchapupu chokuporesa. A zvishomanana kuwedzera alt ari trimester pamuviri wokutanga, zvinonzi anobvumirwa, asi anofanira kuzodzosera kuongorora ropa aminotransferase, kunzvenga kuvadza chiropa.

Nemakemikari Kuongororwa ropa (zviratidzo zviri alt, AST) riri basa apo fungira kardioinfarkt, ivo vachiri chiratidzo panguva chirwere ichi yakaoma. Tsanangudzo AST panguva nokukanganisika pachisara runoita rokuongorora uye kuongorora zvimwe zvachinja simba rinomutsa nomwoyo tsandanyama, chiropa zvirwere uye zvirwere striated musculature.

Kugadzirira ropa kuunganidzira kudzidza

Ropa nemakemikari omuviri kuongorora inotorwa kubva tsinga mangwanani usina chawadya. Panguva iyo kuongorora kufamba 8:00. kubva wokupedzisira kushandiswa foodstuff. 24 awa. kuti ropa zvakabudiswa hakubvumidzwi doro uye zvakakanyiwa namafuta uye mafuta zvokudya. Zvinokurudzirwa kuti kuderedza fiznagruzki. Pakarepo shure Ultrasound, X-ray, fluorography kudzidza, colonoscopy kana physiotherapy ropa haisi varumbidzwa kusarudza kuti pachisara zvikasadaro zvichanzi akavhiringika inopangidza nemakemikari omuviri. Kwevhiki 1-2. zvidzidzo nokukanganisika vanofanira kurega kutora mishonga. Kana hazvibviri kusangana ichi, nenzira chiremba pachisara katsamba pamusoro negashiro zvinodhaka uye dzavo chipimo chemushonga. Pazuva nokukanganisika kuongorora ropa (inopangidza pamusoro alt, AST) kunogona kuchinjwa rinorema fiznagruzki, uyewo kushandisa doro uye vakabata hemolysis.

Achiongorora zvaive bvunzo ropa - alt, AST: wokuyera

Chii vanoverengeka makemikari izvi zvinofanira kuchengetwa nenzira ropa utano hwevanhu? Kubudisa kemesitiri ropa (inopangidza alt, AST), mwero vakadzi - kubvira 31 kusvika 35 zviumbu muzana fő ropa. Kuti simba pabonde, mufananidzo uyu zvishoma zvakasiyana. Normal alt neropa varume (kudzidza nezvezvinhu zvipenyu decoding) - kubva 41 kusvika 50 U / L. In vacheche (kusvika 1 mwedzi.) Rinoenderana chakaipa pakuverenga 75 zviyero, kubva 2 kusvikira mwedzi 12. - hapana kupfuura 60 zviyero, uye kubva gore rimwe uye kusvika 14 makore - asingasviki 45 dzakabatana. Blood kuongorora (decoding alt, AST) rurefu chiratidzo zvingaratidza cirrhotic kukuvara kana rikwanise chiropa kuzvimba, congestive kana hemolytic jaundice, dzimwe chiropa chirwere (uye neoplasms r. H), angina mu nezvokubvuta danho, chenjera rheumatic carditis, myopathy, bile stasis , thromboembolic chirwere pulmonary embolism uye rikwanise pfungwa nomuviri zvemwana asati. Alt uye AST bvunzo ropa (decoding) pamwe kuwedzera zvairatidza kuchengetwa yaizoitika kukuvara, cardiac kuvhiya kana angiokardiografii. Inosimudzira AST zvazvingava 20-50 nguva mune zvimwe zviitiko, uchapupu chiropa chirwere, achiperekedzwa necrosis, hepatitis uye nemavhairasi etiology. Yakakwirira kwevari AST 2-5 nguva vanogona kutaura hemolysis zvirwere, tsandanyama kunotevera, rikwanise pfungwa nomuviri zvemwana asati uye neronda rinonyenga. Kana chinopedza mananara ari tsandanyama uye dermatomyositis vakachengeta ane 8-nedanga kuwedzera IZVOZVO.

coefficient Rytis

Kuti vawane kuongorora yakarurama mhinduro ropa alt uye AST (decoding) inoratidza ukama zviratidzi transferases. ukama Izvi zvinoratidza coefficient of Ritis inoitwa chimwe chidzidzo serum. Kana nhamba pamusoro ndozvakajairwa (N = 1,3), inoratidza kuvapo kardioinfarkta, uye kana zviri pasi pomureza zviratidzi - pamusoro nemavhairasi chiropa.

Sezvo aminotransferases vane zvinyama localization, ropa kuongorora kunoratidza decoding AST myocardial zvokurwara uye alt - chiropa zvokurwara, i.e. kuvapo cellular marara:

• Kana paine ane zvinopfuura 2 kana kakawanda, mumwoyo kuziva chomwoyo.

• A bvunzo ropa alt uye AST (inopangidza) akaratidza chinokosha zvakanyanyisa - uchapupu zvinotapuriranwa chiropa ari incubation nguva.

• By kuderedza aminotransferase zviratidzi - kushayikwa pyridoxine muviri. Pane vanoda difdiagnostiki pamuviri.

nzira

Kazhinji, ari serum transferase zviripo bhuku duku. nzira dzose kuvandudza nzira aminotransferase fanira achiona kuongorora.

Kutanga nokukanganisika kuongorora ropa (inopangidza pamusoro alt, AST) yechipiri inofanira kuitwa. Re-kuongorora zvimwe munhu (anyatsoronga) anenge mumwe pavatatu nyaya kuratidza kwomuzvarirwo siyana.

Next unofanira kunyatsofunga kuunganidza nhoroondo uye kuitisa kuongorora zvizere.

Basa Nhoroondo pakuita Decryption

Nhoroondo Past zvinosanganisira mashoko pamusoro negashiro mishonga, ropa, kuvapo jaundice kana chiropa chirwere, rwapedyo zvirwere chiropa kana kuvapo cirrhotic kwacho kwake abdominal marwadzo, kenza, chirwere cheshuga, kufutisa kana, Ukuwo, nokukurumidza uremu.

Family chiropa chirwere - ndiko doro nedoro, Wilson kuti chirwere , uye vamwe.

Kana alt uye bvunzo AST ropa (inopangidza) akaratidza kupfuura kwomuzvarirwo tsika mu isingasviki miviri nguva, zvakakodzera kuronga kutarisira uye rokuongorora 2-mudanga. Nzira iyi ndiyo Zvakanyanya Kunaka Panguva Yepamuviri varwere.

A bvunzo ropa alt uye AST - inopangidza mune zvimwe zvirwere

The zvishomanana kuwedzera lipid transferases anoratidza nonalcoholic chiropa kukuvara mhando, kusanganisira "mafuta chiropa", nonalcoholic steatogepatoz, nemavhairasi kuzvimba chiropa mune chirwere chimiro.

Mwero kuwedzera angawanika nemavhairasi kana zvinwiwa chiropa kuzvimba uye siyana chisingaperi chiropa chirwere kana pasina cirrhotic kukuvara nayo.

Yakakwirira nhanho runowanzoitika chakasimba zvikuru chiropa, chepfu kana zvinodhaka necrosis, kuvhunduka kana hepatic ischemia.

Hatigoni yakakwirira nhanho (kupfuura 2,000-3,000 U / L) iripo nokuda overdosing acetaminophen uye kushandisa nzira doro-nemataundi varwere vari kurohwa nehana uye / kana hepatic ischemia.

Zvinofanira kucherechedzwa, sezvo alt riri masero matsvuku eropa, zvakafanira kudzivirira akoromoke kwegadziriro serum kuti ongororo. Alt anogona kuderedzwa kana kuchengetwa serum kwemazuva anoverengeka.

Basa dzokurapa mano, makwenzi nezvimwe zvinhu

Kunyatsoverenga nhoroondo kupinza uye decoding rabhoritari zvabuda zvinokosha achizivisa zvinodhaka Kutemeswa kunowedzera transferases. Similar kukuvara chiropa dzakaonekwa muna 1-2% nyaya echirwere kuzvimba chiropa fomu. Vari chokuita nokutora nemishonga, antiepileptics, FIs ose hydroxymethylglutaryl-CoA reductase FIs, nonsteroidal Anti-anogumbura zvinodhaka uye medicaments nokuda nokurapa tibhii.

Nyore nzira yokuziva kuvimba kuti zvibereko aminotransferases pamwe chero nzira - yokubvisa nayo, uye kuchengeta enzayemu revarombo. No kukanzura kunoreva ukama ichi hazvigoni kutsunga.