Paunosarudza tetracycline. Mirayiridzo

Tetracycline ndeyeboka rezvem pharmacological remazita ane zita rimwe chete. Mune chimiro chayo chakachena, iyo ipilistine powder yeruva ruvara, inororless, inonaka inorwadza. Inoratidza kukwanisa kuderera kuparara kwete mumvura chete, asiwo mune doro. Zvimwe zvinowanzoita kuparara mune zvakasimba acid uye alkalis. Ane hygroscopicity. Nekugara kwenguva yakareba muchiedza kune imwe nzvimbo inosviba.

Izvozvo zvinoshandiswa mune zvemasitrocline zve tetracycline zvinobvumira kuti zviitanidzwe kune zvinhu zvehutachiona hwema antibacterial spectrum, inoratidzira britteriostatic property. Tetracycline inokonzera kushungurudzika pakuumbwa kwedambudziko pakati pe ribosome uye kutakura RNA, iyo inotungamirira kuvhiringidziro mukuita kweprotini synthesis. Ari kushanda maererano nehuwandu hwemashoko e-gram - negative, mabhakitiriya eGam-positive, uye anokwikwidza kurwisana nezvimwe zvipembenene zvakawanda.

Asi panewo urongwa hwehutachiona hunopesana neizvi. Zvakakosha kuonana nachiremba usati watora mishonga ine tetracycline. Mirayiridzo inopa ruzivo rwehuwandu chete uye haisi mutungamiri wekuzvirapa.

Ihwo hunoshamisa hweiyo chinhu chakakosha, 75-77%, yezvokudya zvekudya, izvo zvinokanganisawo nekudya kwezvokudya uye kuumbwa kwayo. Mushonga unotorwa usati wapedza kudya, kunyanya kana kudya kunova nemishonga yemakaka, inowedzera zvakanyanya kudarika pane isina chinhu mudumbu. Kurapa kunoitwa kunoitika apo mamwe mafungiro mumuviri anosvika, sekutonga, mazuva maviri okugadziriswa nguva dzose anodiwa pane izvi.

Tetracycline inoratidza hukuru hwakanaka hwekupinda muzvimedu zvakasiyana-siyana uye nhengo, zvipenyu zvehupenyu. Inogona kuunganidzwa mumapfupa, spleen, chiropa, matumire, meno. Iyo inokwanisa kukurira iyo placenta uye inopinda mumukaka wamai. Iyo chinhu chiri mumuviri womunhu kwenguva refu. Mumaawa 12 okutanga, itsvo dzinochenesa muviri we tetracycline kwe 10-20% yemutengo. Chikamu chemuti muhuwandu hwe5-10% yehuwandu neB bile inowira mumukati, asi kune mukana wekusarura zvishoma, uye iyo inodzoka zvakare mumuviri.

Itai tetracycline zviratidzo zvekushandisa mune zvirwere zvinotapukira. Neyo pneumonia uye kuputika kwezvirwere zvirwere, inorayirwa kutora mukati. Mafuta ane tetracycline, murayiridzo wekushandisa unokurudzira kushandiswa kwekurapa acne vulgaris uye mabhakitiriya ganda zvirwere. Mafuta ekuzora maziso ("Tetracycline Acos") pamusana pezvinodhaka izvi zvinoshandiswa kuporesa mabhakitiriya maziso. Itaiwo tetracycline madonhwe maziso.

Mishonga yakawanda ine zita ravo, semuenzaniso, "tetracycline-lekT". Inotaurira ruzivo rwehuwandu hwetetracycline huripo, murayiridzo wezvimwe zvinodhaka.

Usatadza kuona zvikamu zve "zvinopesana" uye "migumisiro". Usakurudzira kutora tetracycline mirayiridzo panguva yechipiri nechetatu mamiriyoni ekuzvitakura, panguva yea lactation uye vana vasati vava nemakore masere. Kuchenjerera kunofanira kushandiswa apo hypersensitivity pavanoshandisa mafuta uye madonhwe. Dzimwe nguva panguva yekugamuchira mishonga yeTetracycline ine mishonga, kusarudzo kusingadiwi kwomuviri kunogona kuitika.

Izvi zvinogona kuratidza sekuderera kwechido, kubuda kwekurutsa uye kushungurudza, kurarisa, glossitis, gastritis, esophagitis, predjazvennogo mudumbu, 12 duodenal ulcer; Kuonekwa kwehutachiona hwemapapa ehururimi, kuora kwemazuva uye zviratidzo zvemunopathological nezvimwe zvinhu zvisingadi. Chero mamiriro ose ezvinhu, kuora kwehutano huzhinji semugumisiro wokushandiswa kwemishonga chero ipi zvayo kunoda kubvunzurudza nechiremba anoenda. Zvinonyanya kukosha kurega kuzvipa-kurapa, pasinei nekuvapo kwebhuku rinotsanangurwa uye rakasiyana nemirairo.