Mazhinji culturing tuvana ezvokunambira kunze kwomuviri waamai. Kukudziridza gametes uye anenge - chii?

Nokuti anopfuura makore makumi maviri vakaroorana vane matambudziko pamwe pamuviri uye kuberekwa kwomwana, aiva mukana muchimiro ezvokunambira kunze kwomuviri waamai muchangosangana chirongwa. Chokwadi, panguva iyoyo zviri zvikuru inodhura. muitiro, nemhaka asingasvavi nguva dzose kusangana zvomurayiro varwere, asi achiri mukana avo vanoda mwana wavo majini. mudumbu tsika nemagariro kunoita kusarudza chete chinonyanya chine musoro, uyewo kubvisa zvimwe zvirwere magene.

mazwi

Ezvokunambira kunze kwomuviri waamai muchangosangana - ndiyo kutungamirirwa pamuviri inoshanda, unosanganisira pakusangana ari zai kunze muchibereko chaamai uye embryo podsazhivaniya vakagadzirira kwemazuva mashanu nemanomwe.

The kurimwa tuvana - ndiko kutsigira kukura uye upenyu tuvana hwevanhu vasati kudyarwazve navo dumbu.

zvokukura IVF

IVF nzira ine matanho akawanda kana maitikiro:
1. kweiyi superovulation, mu zvakafanana pamwe richiona nezvezvabuda follicle Genesis uye kukura endometrium.
2. Follicle ponji.
3. oocyte pakusangana ezvokunambira kunze kwomuviri waamai uye culturing tuvana.
4. chakagadzirwa vanochengetedza luteal chokutambudzika kumwedzi.
5. mudumbu kusonanidzwa uye chirwere akazvitakura.

Vakadzi vaduku mukana IVF pasina superovulation.

Zvairatidza uye Contraindications kuti IVF

Zvinotarisirwa kuti ichi kuchinja rwekuchipatara kuvapo hadzi kushaya mbereko kuti husingakwanisi kwakajairika kurapa, chero kuti IVF anotipa soro ndingangokuvara pamuviri.

Contraindications zvakafanana:
- extragenital zvokurwara, kutyisidzira pamuviri;
- malformations uye deformations of dumbu;
- mapundu of dumbu uye ovaries;
- chenjera anogumbura zvirwere (kwete chete dzokubereka nadzo);
- kuvapo kenza munhau.

Kugadzirira IVF

Danho rokutanga - kuunganidzwa kwemari Kuongororwa uye kuziva miedzo pathologies. Kuti aite izvi, murwere unofanira kupfuura kuongororwa ropa kuti mahormone, uyewo detailed Analyses kuti vakawanda nemakemikari omuviri uye tollerantnost shuga. Akaita zvakafanira kushingaira pamusoro urogenital noutachiona uye Ultrasound yomunyika nhengo dzokubereka nadzo.

Partner anofanira kuita urume kuongorora kuti ritsigire asipo mukono kushaya mbereko. Hazvo achitora zodzera cytology uye colposcopy kuti asava pre-kenza ezvinhu. mai pamuviri vari kuitisa chidzidzo musi romoto zvirwere (rubella, toxoplasmosis, herpes, cytomegalovirus uye chlamydia), sezvo izvi kungaita yemberi kukura azvarwa. Panoperera ari Ultrasound Ongororo yacho mammary omumuviri uye thyroid.

Danho rechipiri rinoitwa pakarepo pamberi kurapwa. Inoitwa nhatu dzinotevera:
- vachizoenda kupfuura miedzo kuti HIV, nemavhairasi chiropa, njovhera, kuwana migumisiro ropa ravo boka uye kusapindirana kweropa chinhu;
- Women zvinofanira kuongororwa kuti shuga ropa, zvakakwana ropa count, weti, nemakemikari omuviri, uyewo kuziva nguva coagulation;
- amai vanepamuviri kunge akagumisa chiremba kuti hapana contraindications kuti pamuviri.

Nzira kuti IVF

First chiremba, mushure ose anodiwa nemiedzo, anodzidza ovarian dzishande mukadzi kuti kuwana mazai zvikuru utano. Pakatanga zvinodhaka rinotanga zuva 21 kumwedzi, uye inogara kwemwedzi. Panguva ino, chiremba anoramba monitors, sezvo follicle dzinokura uye anovaka endometrium ari dumbu uchishandisa Ultrasound. Uye sezvo mukadzi atora inoongorora pamusoro mahormone, kuti ndione mufananidzo yose. Panongotanga zai woibvisa, outpatient nzira kuitwa kurega kwavo. Zvisinei, izvi zvinogona kudzivisa zvimwe zvinhu:
- kushaya ovarian Kupindura dzishande;
- kuvapo adhesions ari pelvic mhango;
- diki ovulation;
- anovulatory kutenderera (apo follicles vakura ane zai). zvinhu zvose izvi zvinofanira kukurukurwa asati Vachinyora vaviri kutanga IVF.

Kana mangoti baba ramangwana kana kusazivikanwa anyatsoronga achapfuura zvinhu zvavo majini zvinogona kuitwa muchangosangana pakuvhiya. Yakareba ezvokunambira kunze kwomuviri waamai mutsika tuvana Zvakakodzera kusarudza kupfuura zvimwe muchando. Mushure memazuva mashanu kana matanhatu pashure muchangosangana, mazai aya vanoverengeka Kutamiswa mudumbu mudumbu amai. Papera vhiki mbiri, amai vanepamuviri donates ropa pachiyero kwevanhu chorionic gonadotropin (HCG) kuziva pamuviri.

Mazhinji kurimwa tuvana

Kakawanda, varwere vari kurapwa rubatsiro rwakadaro chaiyo zvokurapa, pane mibvunzo yakawanda. Mumwe wavo anoenda sezvizvi: "The tsika gametes uye tuvana chii?", The mhinduro iri nyore zvikuru uye kunzwisisa panguva imwe chete. Ndicho nzira naro embryo mupenyu kuti isina kuvakirwa mumuviri waamai. Mazhinji kurimwa tuvana ezvokunambira kunze kwomuviri waamai zvinodhura, yepamusorosoro nzira chinoda ruzivo chaizvo uye unyanzvi. Modern mumarabhoritari vari kuramba vari nani ari Nzira wekusangana uye michina. Ichangobva utsanzi - kurima tuvana muna EmbrioGen zvakatipoteredza. Zvimwe kukura Zvinhu anopa refu ndingangokuvara mudumbu muchibereko ari uterine pamadziro.

Pakuvamba, kurima tuvana akapa simuka chete musengwa pachikuva uye akaisa muna dumbu ane mazuva matatu mushure "pamuviri", asi midzi chete kota zvose zviitiko IVF. Asi pashure kuva nzira ezvokunambira kunze kwomuviri waamai mutsika tuvana kuti Blastocisto pachikuva, kubudirira nzira kwakawedzera. Izvi zvaida itsva tsika nevezvenhau uye incubators.

Zvayakanakira nezvayakaipira pamusoro nzira

nzira rwakadaro kuratidza tsika tuvana inotevera padanho.

1. Zvinobatsira kusarudza zvikuru vaizotibata tichitaura muchibereko tuvana.
2. It kunoderedza uwandu chromosomal abnormalities, sezvo Blastocisto Danho zvinoita kuronda uye kudzivirira.
3. Rine zvimwe vasiri kutaura.
4. It kunoderedza ngozi siyana pamuviri, nekuti zvakakwana vaviri chete anenge panzvimbo mashanu, sapakutanga, kuti ave nepamuviri.
5. Ectopic pamuviri rinowanikwa munguva isingasviki pamberi.

Zvisinei, pane zvazvakashatira nzira iyi. Chokutanga ndechokuti havasi nuclei zvose zvinogona kukura kusvika achida pachikuva. Vachiri mazai chenguva duku maitiro uye tsika nhau vachiri kugadzirisa, sezvo pedyo sezvinobvira dzinongoitika ezvinhu. Kana anenge asingasviki mana chinopukunyuka, ipapo mukana kuti vachava vakagadzirira kudyarwazve, ishoma zvikuru. Mumwe kubvisa, sapamazuva zvapfuura mushanduro IVF - hazvivimbisi mhedziso kubudirira. No chiremba-dzokubereka nadzo munyika haangavi ita kuti nzira iyi ndicho chokwadi chisingaperi. Masayendisiti vachiri kuedza kuti.

Side migumisiro IVF

Nemigumisiro pashure IVF, munguva iyo inoshandiswa kwenguva yakareba tuvana ndiwo:
- pamuviri pevana vakawanda sezvo akawanda embryo Kutamiswa mudumbu;
- ectopic pamuviri (kufamba hazvigoni kunze mudumbu mukati dumbu);
- kunyanya kweiyi pakati ovaries (ovarian hyperstimulation chirwere kunotungamirira mbereko);
- utachiona uye ropa.